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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Penegra 50 Tablet is used to treat erectile dysfunction (impotence) in adult men. Additionally, it may also be used to treat pulmonary arterial hypertension (high blood pressure in the lungs) in adults to improve the ability to exercise and to slow down clinical worsening. It contains Sildenafil, which works by relaxing the blood vessels in the penis, thereby allowing the blood to flow into the penis when the person is sexually excited. Thus, it helps treat erectile dysfunction. It relaxes blood vessels, increases the blood supply to the lungs and reduces the workload of the heart. Thereby, helps to treat pulmonary hypertension. In some cases, it may cause side effects such as headache, nausea, dizziness, indigestion and stomach upset. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

SILDENAFIL-50MG

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Penegra 50 Tablet

Penegra 50 Tablet belongs to the group of medicines called phosphodiesterase type-5 (PDE 5) inhibitors primarily used to treat erectile dysfunction (impotence) in adult men. Additionally, Penegra 50 Tablet may also be used to treat pulmonary arterial hypertension (high blood pressure in the lungs) in adults to improve the ability to exercise and to slow down clinical worsening.
 
Penegra 50 Tablet works by relaxing the blood vessels in the penis, thereby allowing the blood to flow into the penis when the person is sexually excited. Thus, Penegra 50 Tablet helps treat erectile dysfunction. Penegra 50 Tablet relaxes the blood vessels, increases the blood supply to the lungs and reduces the workload of the heart. Thereby, treating pulmonary hypertension.
 
You are advised to take Penegra 50 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Penegra 50 Tablet may cause side effects such as headache, nausea, dizziness, indigestion and stomach upset. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Do not take Penegra 50 Tablet if you are allergic to any of the components or if you are taking nitrate medicines or riociguat (a drug used to treat pulmonary hypertension). Penegra 50 Tablet is not recommended for use in children. Consult your doctor if you experience hearing or visual impairment. Avoid consumption of alcohol as it may impair your ability to get an erection. Taking Penegra 50 Tablet after a heavy meal might take longer time for the medicine to work; therefore you are advised to take Penegra 50 Tablet with light meals.

Uses of Penegra 50 Tablet

Treatment of Erectile dysfunction (impotence) and pulmonary arterial hypertension.

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water as a whole. Do not crush, break or chew the tablet. Syrup/Suspension: Shake the bottle well before use. Take the prescribed dose using the measuring cup provided by the pack.Powder for oral suspension: Check the label for directions before use. Add the prescribed quantity of water to the powder, close the cap and shake vigorously for 30 seconds. Take the prescribed dose using the dosing syringe.Sachet: Open the sachet and consume the entire contents.Orally disintegrating strip: Keep the strip in the mouth and allow it to disintegrate. Do not swallow as a whole. Avoid handling the strip with wet hands.Jelly: Place the jelly in the mouth or under the tongue and allow it to dissolve.Effervescent tablets: Check the label for directions and take it as advised by the doctor. Dissolve the effervescent tablet in half a glass of water and consume the solution immediately.

Medicinal Benefits

Penegra 50 Tablet belongs to the group of medicines called phosphodiesterase type-5 (PDE 5) inhibitors, primarily used to treat erectile dysfunction (impotence) in adult men and pulmonary arterial hypertension (high blood pressure in the lungs) in adults to improve the ability to exercise and to slow down clinical worsening. Penegra 50 Tablet works by relaxing the blood vessels in the penis, thereby allowing the blood to flow into the penis when the person is sexually excited. However, Penegra 50 Tablet helps the person to get an erection only if he is sexually stimulated. Penegra 50 Tablet relaxes the blood vessels, increases the blood supply to the lungs and reduces the workload of the heart. Thereby treating pulmonary hypertension.

How Penegra 50 Tablet Works

Penegra 50 Tablet works by relaxing the blood vessels in the penis, thereby allowing the blood to flow into the penis when the person is sexually excited. Thus, Penegra 50 Tablet helps treat erectile dysfunction. Penegra 50 Tablet relaxes the blood vessels, increases the blood supply to the lungs and reduces the workload of the heart. Thereby, treating pulmonary hypertension.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Penegra 50 Tablet

  • Headache
  • Nausea
  • Dizziness
  • Indigestion
  • Stomach upset

What if I have taken an overdose of Penegra 50 Tablet

Do not take more than the prescribed dose of Penegra 50 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Penegra 50 Tablet if you are allergic to any of the components, if you are taking medicines called nitrates which are used to treat angina or chest pain, or guanylate cyclase stimulator medicines (used to treat heart failure and PAH). Inform your doctor if you have/had heart problems such as angina, heart attack, irregular heartbeat, or heart failure, blood circulation problems, low blood pressure, eye or ear problems, sickle cell anaemia (an abnormality of red blood cells), multiple myeloma (cancer of bone marrow), leukaemia (cancer of blood cells), stomach ulcer, bleeding problems, problems with the shape of the penis or Peyronie's disease (a condition that causes painful erections).

Drug-Drug Interactions

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SildenafilAmprenavir
Critical
SildenafilNitroprusside
Critical

Drug-Drug Interactions

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SildenafilAmprenavir
Critical
How does the drug interact with Penegra 50 Tablet 4's:
Coadministration of Amprenavir and Penegra 50 Tablet 4's can increase the blood levels and effects of Penegra 50 Tablet 4's.

How to manage the interaction:
Taking Amprenavir and Penegra 50 Tablet 4's together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SildenafilNitroprusside
Critical
How does the drug interact with Penegra 50 Tablet 4's:
Coadministration of Penegra 50 Tablet 4's with Nitroprusside can increase the risk of developing low blood pressure.

How to manage the interaction:
Taking Penegra 50 Tablet 4's with Nitroprusside together is generally avoided as it can lead to an interaction, it can be taken only if prescribed by your doctor. If you experience any side effects such as dizziness, lightheadedness, headache, or heart palpitations you should seek immediate medical attention. Do not discontinue any medications without consulting your doctor.
SildenafilRitonavir
Critical
How does the drug interact with Penegra 50 Tablet 4's:
Coadministration of Ritonavir and Penegra 50 Tablet 4's may significantly increase the blood levels of Penegra 50 Tablet 4's.

How to manage the interaction:
Taking Penegra 50 Tablet 4's with Ritonavir together is generally avoided as it can possibly result in an interaction, it can be taken only if your doctor has advised it. If you notice any of these symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact a doctor. Do not discontinue any medications without consulting a doctor.
SildenafilAtazanavir
Critical
How does the drug interact with Penegra 50 Tablet 4's:
Combining Atazanavir and Penegra 50 Tablet 4's can increase the blood levels and side effects of Penegra 50 Tablet 4's.

How to manage the interaction:
Taking Atazanavir and Penegra 50 Tablet 4's together is avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SildenafilIsosorbide dinitrate
Critical
How does the drug interact with Penegra 50 Tablet 4's:
Coadministration of Isosorbide dinitrate and Penegra 50 Tablet 4's can increase the risk of low blood pressure.

How to manage the interaction:
Taking Isosorbide dinitrate and Penegra 50 Tablet 4's together is generally avoided as it can lead to an interaction, it can be taken only if advised by your doctor. However, if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity) contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SildenafilIndinavir
Critical
How does the drug interact with Penegra 50 Tablet 4's:
Coadministration of Indinavir and Penegra 50 Tablet 4's can increase the blood levels and side effects of Penegra 50 Tablet 4's.

How to manage the interaction:
Taking Indinavir and Penegra 50 Tablet 4's together is avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SildenafilDarunavir
Critical
How does the drug interact with Penegra 50 Tablet 4's:
Combining Darunavir and Penegra 50 Tablet 4's can increase the blood levels and effects of Penegra 50 Tablet 4's.

How to manage the interaction:
Taking Darunavir and Penegra 50 Tablet 4's together is avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SildenafilTelaprevir
Critical
How does the drug interact with Penegra 50 Tablet 4's:
Combining Telaprevir and Penegra 50 Tablet 4's can increase the blood levels and effects of Penegra 50 Tablet 4's.

How to manage the interaction:
Taking Telaprevir and Penegra 50 Tablet 4's together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SildenafilFosamprenavir
Critical
How does the drug interact with Penegra 50 Tablet 4's:
Coadministration of Fosamprenavir and Penegra 50 Tablet 4's can increase the blood levels and effects of Penegra 50 Tablet 4's.

How to manage the interaction:
Taking Fosamprenavir and Penegra 50 Tablet 4's together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SildenafilRiociguat
Critical
How does the drug interact with Penegra 50 Tablet 4's:
Co-administration of Penegra 50 Tablet 4's with Riociguat may lower the blood pressure.

How to manage the interaction:
Taking Riociguat and Penegra 50 Tablet 4's together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, flushing, headache, and nasal congestion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintaining a healthy weight, eating balanced diet and regular exercising may help you manage erectile dysfunction.

  • Avoid consumption of alcohol as it may temporarily impair your ability to get an erection.

  • Avoid usage of tobacco.

  • Share intimate time with your partner.

Habit Forming

No

Therapeutic Class

PDE5-INHIBITORS

Penegra 50 Tablet Substitute

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Alcohol

Unsafe

You are advised not to consume alcohol as it might temporarily impair your ability to get an erection.

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Pregnancy

Caution

For erectile dysfunction: Penegra 50 Tablet is not indicated for the treatment of sexual problems in women.For pulmonary arterial hypertension: Consult your doctor if you are pregnant. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

For erectile dysfunction: Penegra 50 Tablet is not indicated for the treatment of sexual problems in women.For pulmonary arterial hypertension: Consult your doctor if you are breastfeeding. Your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Caution

Penegra 50 Tablet may cause dizziness and blurred vision, therefore you are advised to drive and operate machinery only if you are alert.

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Liver

Caution

Penegra 50 Tablet should be used with caution in patients with liver impairment/liver disease. Dose adjustment may be needed in such patients.

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Kidney

Caution

Penegra 50 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed in such patients.

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Children

Unsafe

Penegra 50 Tablet is not recommended for children under the age of 18.

FAQs

Penegra 50 Tablet is primarily used to treat erectile dysfunction (impotence) in adult men. Additionally, Penegra 50 Tablet may sometimes be used to treat pulmonary arterial hypertension (high blood pressure in the lungs) in adults to improve the ability to exercise and to slow down clinical worsening.
Penegra 50 Tablet works by relaxing the blood vessels in the penis, thereby allowing the blood to flow into the penis when the person is sexually excited.
No, do not take Penegra 50 Tablet with nitrates. Taking Penegra 50 Tablet with medicines used to treat angina/chest pain such as nitrates/nitroglycerin may cause severe lowering of blood pressure. Consult your doctor if you have a history of heart attack/stroke.
Caution is advised if Penegra 50 Tablet is taken with alpha-blockers or blood-pressure-lowering medicines. Penegra 50 Tablet relaxes and widens the blood vessels; this causes a decrease in blood pressure. Therefore, if Penegra 50 Tablet is taken along with blood-pressure-lowering medicines it might cause further lowering in blood pressure. Consult your doctor if you are taking alpha-blockers or anti-hypertensives.
In some cases, Penegra 50 Tablet may cause sudden vision loss in one or both eyes. Stop taking Penegra 50 Tablet and consult your doctor immediately if you experience a sudden decrease or loss of vision.
Penegra 50 Tablet may cause low blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking; instead, lie down and get up slowly only when you feel better.
You can take Penegra 50 Tablet with or without food. However, if you take sildenafil with a high-fat meal, it will take longer for the medication to start to work. therefore, you are advised to take Penegra 50 Tablet with light meals.
Never take 2 doses at the same time. It could lead to severe adverse events.
Penegra 50 Tablet is only available with a prescription.
Penegra 50 Tablet has been demonstrated to be effective in treating premature ejaculation (PE). However, it should be taken only if prescribed by the doctor.
It is not always the best choice to use long term. It's possible to develop long-term side effects from sildenafil treatment. Seek medical attention if you have any concerns regarding this.
The combination of nitrates with sildenafil is contraindicated. This combination must be avoided as it can produce significant hypotension and is potentially fatal.
Sildenafil's vasodilating action affects both the arteries and the veins, causing small decreases in systolic and diastolic blood pressures. However, clinically significant hypotension is rare.
Most men aged 18 and over can take Penegra 50 Tablet for erectile dysfunction.
There's no clear evidence to suggest that taking sildenafil reduces fertility in either women or men. Speak to your doctor before taking it if you're trying to get pregnant.
Penegra 50 Tablet has no acute effects on the male fertility profile.
While Penegra 50 Tablet may increase blood flow to the penis, it doesn't raise blood pressure.
Penegra 50 Tablet is an effective and well-tolerated treatment for erectile dysfunction in men with diabetes if prescribed by the doctor.
You can take Penegra 50 Tablet, an erectile dysfunction medication, every day, up to the maximum recommended dosage of 100mg.
Take Penegra 50 Tablet as needed before engaging in sexual activity. The optimal time to take sildenafil is around an hour before sexual activity, however it can be taken anytime between 4 hours and 30 minutes before. Sildenafil should not be taken more than once every 24 hours.
Yes, you can consume alcohol while taking Penegra 50 Tablet. However, drinking excessively can make it more difficult to achieve an erection. If you're taking sildenafil to treat erectile dysfunction, don't consume too much alcohol before taking it.
Penegra 50 Tablet is not suitable for some people. To make sure it's safe for you, speak to your healthcare professional before taking sildenafil.
Penegra 50 Tablet should never be used in children for erectile dysfunction. In general, sildenafil should not be used for pulmonary arterial hypertension in children, especially for chronic use.
If you experience a prolonged or painful erection for 4 hours or more, contact your doctor immediately.
In some cases, it may cause side effects such as headache, nausea, dizziness, indigestion and stomach upset.
Penegra 50 Tablet treats erectile dysfunction by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection.
Take Penegra 50 Tablet as needed before sexual activity. The best time to take sildenafil is about 1 hour before sexual activity. Swallow it as a whole with a glass of water as a whole. Do not crush, break or chew the tablet.

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Other Info - PEN0007

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