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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Nov 23, 2024 | 4:49 PM IST
Paximant-LS Tablet 10's is used in the treatment of depression. It contains Clonazepam and Paroxetine, which increases levels of a calming chemical in the brain and also increases the serotonin hormone levels that improve mood, behaviour and prevent symptoms of depression. It may cause common side effects such as nausea, vomiting, diarrhoea, memory impairment, uncoordinated body movements, drowsiness, low sexual desire and delayed ejaculation. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

La Mante Healthcare

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Paximant-LS Tablet 10's

Paximant-LS Tablet 10's belongs to a group of medicines called ‘antidepressants’. It is used in the treatment of depression. Depression is a common mood disorder, which negatively affects a person's daily life described as feelings of sadness, loss, or anger. Depression symptoms can vary from mild to severe and can include: feeling sad, thoughts of death or suicide, loss of interest, weight loss or gain unrelated to dieting, trouble sleeping, loss of energy, feeling worthless or guilty and difficulty thinking.

Paximant-LS Tablet 10's is a combination of two drugs: clonazepam and paroxetine. Clonazepam increases levels of a calming chemical, gamma-amino-butyric-acid (GABA), in your brain. Paroxetine increases the serotonin hormone levels that improve mood, behaviour and prevent symptoms of depression.

You are advised to take Paximant-LS Tablet 10's for as long as your doctor has prescribed it for you depending on your medical condition and response to the treatment. In some cases, you may experience certain common side-effects such as nausea, vomiting, diarrhoea, memory impairment, uncoordinated body movements, drowsiness, low sexual desire and delayed ejaculation. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

To treat your condition effectually, continue taking Paximant-LS Tablet 10's for as long as your doctor has prescribed. Do not take Paximant-LS Tablet 10's if you are pregnant or breastfeeding unless prescribed by the doctor. Paximant-LS Tablet 10's causes drowsiness, sleepiness, do not drive unless you are alert. Paximant-LS Tablet 10's should not be given to children and adolescents aged 18 years for treating depression. Avoid consuming alcohol along with Paximant-LS Tablet 10's as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Paximant-LS Tablet 10's

Treatment of Depression

Medicinal Benefits

Paximant-LS Tablet 10's is a combination of two drugs: clonazepam and paroxetine. Clonazepam is a benzodiazepine, which works by increasing levels of a calming chemical, gamma-amino-butyric-acid (GABA), in your brain. Paroxetine is an antidepressant that increases the serotonin hormone levels that improve mood, behaviour, and prevent symptoms of depression.

Directions for Use

Take Paximant-LS Tablet 10's with or without food. Paximant-LS Tablet 10's should be swallowed as a whole with a glass of water; do not chew or crush it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Paximant-LS Tablet 10's

  • Nausea
  • Vomiting
  • Diarrhoea
  • Memory impairment
  • Uncoordinated body movements
  • Drowsiness
  • Low sexual desire and delayed ejaculation

Drug Warnings

Do not take Paximant-LS Tablet 10's if you are allergic to Paximant-LS Tablet 10's or any other ingredients in it. Tell your doctor if you are taking antidepressants, antipsychotic medication, antihypertensives, or pain medication. Talk to your doctor if you have a history of seizures, bipolar disorder, suicide attempts, or schizophrenia. Patients with liver diseases, diabetes, heart disease, lung disease and bleeding disorders should use Paximant-LS Tablet 10's with caution. Please do not stop the treatment abruptly as it can cause withdrawal reactions. Paximant-LS Tablet 10's is not recommended to use in children and adolescents under 18 years of age as it increases suicidal tendencies in this population. Consult your doctor immediately if you experience suicidal thoughts such as killing or harming yourself while on this medication. Do not take Paximant-LS Tablet 10's if you are pregnant or breastfeeding unless prescribed. Paximant-LS Tablet 10's causes drowsiness and dizziness, do not drive unless you are alert. Avoid consuming alcohol along with Paximant-LS Tablet 10's as it could lead to increased drowsiness and dizziness.

Drug Interactions

Drug-Drug Interactions: Paximant-LS Tablet 10's may have interaction with pain killers (tramadol, aspirin, acetaminophen/hydrocodone, and pethidine), narcotic pain relievers(morphine, codeine), blood thinners (warfarin), cholesterol medications (pravastatin), fits medication (phenobarbital, phenytoin, sodium valproate or carbamazepine), anti-depression medication (aripiprazole, escitalopram), blood pressure medications (metoprolol) and medications to treat heartburn, stomach problems (Cimetidine).

Drug-Food Interactions: Avoid consuming alcohol along with Paximant-LS Tablet 10's as it may increase the sedative effects, and one can also experience impairment in thinking and judgment.

Drug-Disease Interactions: Paximant-LS Tablet 10's may have interactions with disease conditions such as heart problems, acute alcohol intoxication, epilepsy, glaucoma, renal/liver disease, respiratory depression and drug dependency.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • PREGABALIN
  • METOPROLOL
  • HYDROCODONE
  • QUETIAPINE
  • ALPRAZOLAM
  • CETIRIZINE
  • ARIPIPRAZOLE
  • ZOLPIDEM
  • LAMOTRIGINE
  • SERTRALINE

Habit Forming

Yes

Diet & Lifestyle Advise

  • Maintain a healthy and well-balanced diet. 
  • Do not take stress as it may aggravate your condition.
  • Limit alcohol intake and quit smoking.
  • Engage in social activities frequently as it may improve self-esteem and confidence. 
  • Limit caffeine intake.
  • Maintain a healthy diet and exercise regularly helps in improving overall health and boosts self-esteem.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.
  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in proper maintenance of neurotransmitters. 
  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.
  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosts self-esteem, and provides restful sleep.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Special Advise

  • Paximant-LS Tablet 10's causes drowsiness. Avoid doing activities that require your complete focus and attention like driving when on this drug.
  • Abrupt stoppage of Paximant-LS Tablet 10's can lead to significant withdrawal symptoms. Always discuss with your doctor about decreasing the dosage before completely stopping its usage.
  • Avoid consuming alcohol while on this medication as it can lead to dangerous side effects.
  • Paximant-LS Tablet 10's is unsafe for usage if you're pregnant or are planning to get pregnant. Discuss with your doctor in such situations about changing/replacing the medicine with safer alternatives.
  • To avoid getting addicted to this drug take it only in prescribed quantities and only as directed by your doctor. Do not self-medicate.

Disease/Condition Glossary

Depression: It is a mood disorder characterised by the feeling of sadness, unhappiness, anger, hopelessness or loss that interferes with a person’s daily activities. Depression can also influence some chronic health conditions and relationships. The exact cause of depression is unknown, but it may be associated with mental problems, trauma, family history, drugs use, and medical conditions.

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Alcohol

Caution

Avoid consumption of alcohol while taking Paximant-LS Tablet 10's as it may cause an increased sedative effect.

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Pregnancy

Unsafe

Paximant-LS Tablet 10's may cause toxic effects to the fetus. So, it is not recommended for use in women who are pregnant or planning to become pregnant.

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Breast Feeding

Caution

Paximant-LS Tablet 10's should be used with caution in breastfeeding mothers. Your doctor may advise you to stop breastfeeding while taking this medication.

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Driving

Caution

Do not drive or operate heavy machinery as Paximant-LS Tablet 10's may cause drowsiness.

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Liver

Caution

Paximant-LS Tablet 10's should be used with caution in patients with severe liver impairment. Dose adjustments may be required in such cases.

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Kidney

Caution

Paximant-LS Tablet 10's should be used with caution in patients with kidney problems. Dose adjustments may be required in such cases. If you have any concerns regarding the use of Paximant-LS Tablet 10's in patients with kidney problems, please consult a doctor.

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Children

Caution

Paximant-LS Tablet 10's should not be used in children unless prescribed by a child specialist.

Country of origin

India

Manufacturer/Marketer address

802, Safal Prelude, nr. Ashwaraj Bunglow, nr. Prahlad Nagar Road, Prahlad Nagar, Ahmedabad, Gujarat 380015
Other Info - PAX0110

FAQs

Paximant-LS Tablet 10's is used in the treatment of depression.
Paximant-LS Tablet 10's causes sleepiness, drowsiness, and dizziness. Do not drive or operate machinery if you experience these symptoms after taking Paximant-LS Tablet 10's.
Paximant-LS Tablet 10's causes weight gain due to increased appetite. Eat a healthy diet and exercise regularly to maintain a healthy weight.
Do not discontinue Paximant-LS Tablet 10's without consulting your doctor as it could lead to recurring symptoms. To treat your condition effectually continue taking Paximant-LS Tablet 10's for as long as prescribed. Moreover, stopping this medicine suddenly may result in withdrawal symptoms. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Paximant-LS Tablet 10's.
Paximant-LS Tablet 10's may cause decreased sex-drive, problems with erection and orgasm. Consult your doctor if you have any concerns regarding this.
Dry mouth could be a side-effect of Paximant-LS Tablet 10's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Some patients experienced increased suicidal thoughts or actions in the first few months of the treatment with Paximant-LS Tablet 10's. Report to your doctor immediately if you notice any changes in your behaviour or mood while on this medication.
Yes, the use of Paximant-LS Tablet 10's can cause sleepiness as a side effect. It's important to avoid driving or operating heavy machinery until you know how Paximant-LS Tablet 10's affects you.
No, it's not safe to drink alcohol while taking Paximant-LS Tablet 10's. Alcohol can increase the sedative effects of Paximant-LS Tablet 10's, leading to increased drowsiness and dizziness. It's best to avoid alcohol to prevent these increased side effects.
Paximant-LS Tablet 10's typically takes several weeks to show full effects, but it may differ from person to person. However, it’s important to complete the full course of treatment as prescribed by your doctor.
Store the Paximant-LS Tablet 10's at room temperature protected from light and moisture. Keep it out of reach of children.
The common side effects of Paximant-LS Tablet 10's are nausea, vomiting, diarrhoea, memory impairment, uncoordinated body movements, drowsiness, low sexual desire and delayed ejaculation. If any of these side effects persist or worsen, please consult doctor.

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