Pause-500 Tablet belongs to the class of medications called ‘anti-fibrinolytic drugs’ used to treat abnormal or unwanted bleeding. It is used to control bleeding in conditions such as heavy periods (menorrhagia), nose bleeds (epistaxis), cervical surgery (conization of the cervix), prostate surgery (post-prostatectomy), bladder surgery (post-cystectomy), bleeding inside the eye (traumatic hyphaema) and a hereditary disease called angioneurotic edema (HANO). The solution form of this medicine is used before tooth removal (dental extraction) in hemophiliacs (people who bleed more easily than normal).

Pause-500 Tablet contains ‘tranexamic acid’, which belongs to the class of ‘anti-fibrinolytic agents’. It is generally used for short-term treatment of bleeding. It acts by regulating the breakdown of blood clots. It blocks the release and action of plasmin, an enzyme essential for the breakdown of clots present in the blood. This effect helps to slow down the bleeding.

Pause-500 Tablet should be taken as advised by your physician. The dose and duration of the medicine will be decided by your doctor based on your health condition. Pause-500 Tablet may not cause any side effects when used orally. However, some patients may experience certain side effects, such as feeling sick (nausea), diarrhea, and itchy skin. These side effects usually go away on their own. If you develop any other serious side effects, such as vision problems while using Pause-500 Tablet , consult your doctor immediately.

Pause-500 Tablet should be avoided if you are allergic to it or if any other ingredients are present in it. Do not take this medicine if you have a history of kidney disease, thrombosis (formation of blood clots in the blood vessels), disseminated intravascular coagulation (a disease where blood clots form throughout your body) , and seizures (fits). Inform your doctor if you are taking birth control pills or fibrinolytic agents (medicines that dissolve blood clots). Also, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding.

Pause-500 Tablet contains ‘tranexamic acid’, which belongs to the class of ‘anti-fibrinolytic agents’. It acts by regulating the breakdown of blood clots in the body. It blocks the release and action of plasmin, an enzyme essential for the breakdown of clots in the blood. This effect helps to slow down abnormal bleeding.

• Nausea
• Diarrhea
• Itchy skin
• Pain at the injection site
• Vision problems
• Vomiting

Before taking Pause-500 Tablet , inform your doctor if you notice blood in your urine (except during periods), or have a history of uncontrollable bleeding, disseminated intravascular coagulation (DIC) (a disease where blood clots form throughout your body), irregular periods, and kidney disease. Also, inform your doctor if you or your family has a history of thrombosis (formation of blood clots in the blood vessels). Let your doctor know if you are taking medicine to treat a hereditary disease called angioneurotic oedema (HANO) every day for a long time. Your doctor may advise regular eye tests and blood tests to check your vision problems and also liver/kidney functioning. Inform your doctor if you are using birth control pills, including the patch, vaginal ring, and an intrauterine device (IUD), as there is a risk of deep vein thrombosis (a condition in which a blood clot is formed in the deeper vein, mostly the legs). Inform your doctor if you are using fibrinolytic agents (drugs that break blood clots) such as streptokinase, as they may stop the effect of Pause-500 Tablet . Inform your doctor if you are pregnant, planning to become pregnant or breastfeeding.

Drug-drug interactions: Pause-500 Tablet may interact with birth control pills, fibrinolytic drugs (streptokinase, urokinase, reteplase, alteplase, and tenecteplase, etc.), an antipsychotic drug (chlorpromazine), and a drug used to treat blood cancer (tretinoin) and progestins (levonorgestrel).

Drug-food interactions: No interactions found.

Drug-disease interactions: Pause-500 Tablet should not be used in patients with a history of colour vision defect, active intravascular clotting, intracranial haemorrhage, seizures (fits) and renal dysfunction.

• CHLORPROMAZINE
• TRETINOIN
• STREPTOKINASE
• UROKINASE
• ALTEPLASE
• RETEPLASE
• LEVONORGESTREL

• Ask your doctor about the exercises you prefer based on your health condition.
• Stay hydrated and consume plenty of fluids. Fluids are necessary to maintain blood flow in your body.
• Consume fresh fruits and vegetables. Consult a dietitian and prepare a diet plan. Eating healthy can help you to recover faster.

• Your doctor may suggest regular eye check-ups while taking Pause-500 Tablet .
• Increased risk of blood clot formation when co-administered with a combination oral contraceptive. Consult your doctor before taking any medication.

Menorrhagia: It is a condition characterized by heavy or prolonged bleeding during menstrual periods which last for more than seven days

Epistaxis: Bleeding from the nose when the blood vessels of the nose lining burst. This can occur due to dryness or nose injury.

Post-operative bleeding: It is bleeding after surgery due to the blood vessel rupture. Some people may experience mild to severe bleeding due to cuts made during surgery.

Traumatic hyphema: This is a condition characterized by blood in the anterior chamber of the eye due to a blunt injury. It may also result in vision loss.

Hereditary angioneurotic edema (HANO): It is a hereditary disease that causes recurrent painless swelling under the skin.

Dental Procedures: It is a procedure involving dental issues during which bleeding occurs.