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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Paribest 40Mg/0.4Ml Inj Pfs is used to prevent or treat blood clots caused by medical conditions, such as unstable angina, after an operation or long periods of bed rest due to illness, after a heart attack, and the formation of blood clots in the dialysis machine tubes. It contains Enoxaparin, which prevents existing blood clots from growing larger, allowing your body to break them down and prevent them from harming you. Also, it inhibits the formation of new blood clots in your blood. It may cause side effects such as increased liver enzymes, skin rash (hives,urticaria), itchy red skin, bruising or pain at the injection site, and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

ENOXAPARIN-10MG

Manufacturer/Marketer :

Swiss Criticure

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Paribest 40Mg/0.4Ml Inj Pfs

Paribest 40Mg/0.4Ml Inj Pfs is used to prevent or treat blood clots caused by medical conditions, such as unstable angina, after an operation or long periods of bed rest due to illness, after a heart attack, and the formation of blood clots in the dialysis machine tubes. A blood clot is a mass of blood that forms when platelets, proteins, and cells in the blood stick together. A blood clot can occur in any body part, leading to a heart attack, stroke, and organ damage (even coma or death).

Paribest 40Mg/0.4Ml Inj Pfs contains Enoxaparin, which is a low molecular weight heparin that works by preventing existing blood clots from growing larger, allowing your body to break them down and prevent them from harming you. On the other hand, it inhibits the formation of new blood clots in your blood.

Paribest 40Mg/0.4Ml Inj Pfs will be administered by a healthcare professional; do not self-administer. Side effects of Paribest 40Mg/0.4Ml Inj Pfs include increased liver enzymes, skin rash (hives, urticaria), itchy red skin, bruising or pain at the injection site, and headache. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, report to your doctor immediately. 

If you are known to be allergic to Paribest 40Mg/0.4Ml Inj Pfs or any other medicines, inform your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before receiving the Paribest 40Mg/0.4Ml Inj Pfs. Also, disclose to your doctor if you have any pre-existing medical conditions like a stomach ulcer, recent surgery of the brain or eyes or spine, recent bleeding stroke, diabetes, high blood pressure, or recent onset of stroke or kidney or liver disorders. Also, let your doctor know if you are underweight or overweight or if you have high levels of potassium in your blood.

Uses of Paribest 40Mg/0.4Ml Inj Pfs

Treatment and prevention of blood clots

Directions for Use

Paribest 40Mg/0.4Ml Inj Pfs will be administered by a qualified healthcare professional. Kindly do not self-administer.

Medicinal Benefits

Paribest 40Mg/0.4Ml Inj Pfs contains Enoxaparin, which is a low molecular weight heparin (LMWH) that helps to treat harmful blood clots due to medical conditions, including unstable angina, after an operation or long periods of bed rest due to illness, after a heart attack, and blood clots forming in the tubes of your dialysis machine. Paribest 40Mg/0.4Ml Inj Pfs works by stopping existing blood clots from getting any bigger; this helps your body break them down and prevents them from causing you harm. On the other hand, it stops new blood clots from forming in your blood.

How Paribest 40Mg/0.4Ml Inj Pfs Works

Paribest 40Mg/0.4Ml Inj Pfs contains Enoxaparin, which is a low molecular weight heparin that works by preventing existing blood clots from growing larger, allowing your body to break them down and prevent them from harming you. On the other hand, it inhibits the formation of new blood clots in your blood.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Paribest 40Mg/0.4Ml Inj Pfs

  • Bleeding
  • Increases in liver enzymes
  • Bruise more easily than usual
  • Pink patches on your skin 
  • Skin rash (hives, urticaria)
  • Itchy red skin
  • Bruising or pain at the injection site
  • Decreased red blood cell count
  • High platelet counts in the blood
  • Headache

What if I have taken an overdose of Paribest 40Mg/0.4Ml Inj Pfs

The overdose of Paribest 40Mg/0.4Ml Inj Pfs is unlikely as it is administered by a doctor. However, if you suspect any adverse reactions or unusual symptoms while on treatment with Paribest 40Mg/0.4Ml Inj Pfs, please inform your doctor immediately.

Drug Warnings

Patients should inform the doctor if they are on active treatment with this Paribest 40Mg/0.4Ml Inj Pfs before any surgery is scheduled. If you are known to be allergic to Paribest 40Mg/0.4Ml Inj Pfs or any other medicines, inform your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using the Paribest 40Mg/0.4Ml Inj Pfs. Before using this Paribest 40Mg/0.4Ml Inj Pfs, disclose to your doctor if you have any pre-existing medical conditions like stomach ulcer, recent surgery of the brain or eyes or spine, recent bleeding stroke, diabetes, high blood pressure, or recent onset of stroke or kidney or liver disorders, And also let your doctor know if you are underweight or overweight or if you have high levels of potassium in your blood.

Drug-Drug Interactions

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EnoxaparinMifepristone
Critical
EnoxaparinDefibrotide
Critical

Drug-Drug Interactions

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EnoxaparinMifepristone
Critical
How does the drug interact with Paribest 40Mg/0.4Ml Inj Pfs:
Combining Mifepristone with Paribest 40Mg/0.4Ml Inj Pfs can increase the risk or severity of side effects of vaginal bleeding.

How to manage the interaction:
Taking Paribest 40Mg/0.4Ml Inj Pfs with Mifepristone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience prolonged, excessive bleeding, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
EnoxaparinDefibrotide
Critical
How does the drug interact with Paribest 40Mg/0.4Ml Inj Pfs:
Combining Defibrotide with Paribest 40Mg/0.4Ml Inj Pfs can increase the risk of bleeding.

How to manage the interaction:
Taking Paribest 40Mg/0.4Ml Inj Pfs with Defibrotide is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
EnoxaparinIbrutinib
Severe
How does the drug interact with Paribest 40Mg/0.4Ml Inj Pfs:
Co-administration of Ibrutinib with Paribest 40Mg/0.4Ml Inj Pfs can increase the risk or severity of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Ibrutinib and Paribest 40Mg/0.4Ml Inj Pfs, but it can be taken if prescribed by a doctor. If you have any symptoms like unusual bleeding or bruising, dizziness, black or bloody stools, coughing up blood, vomiting blood, severe headache, or weakness, contact a doctor immediately. Do not stop using any medications without a doctor's advice.
EnoxaparinStreptokinase
Severe
How does the drug interact with Paribest 40Mg/0.4Ml Inj Pfs:
Taking streptokinase can enhance the blood-thinning effects of Paribest 40Mg/0.4Ml Inj Pfs which can increase the risk or severity.

How to manage the interaction:
Taking Paribest 40Mg/0.4Ml Inj Pfs with Streptokinase together can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like pain in the middle of your back, feeling numb, problems with your bowels or bladder, bleeding, very heavy bleeding that could be dangerous, complications, bruises, feeling dizzy or lightheaded, seeing red or black stools, having a severe headache, bleeding, vomiting, or feeling weak it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
EnoxaparinTirofiban
Severe
How does the drug interact with Paribest 40Mg/0.4Ml Inj Pfs:
Combining Tirofiban with Paribest 40Mg/0.4Ml Inj Pfs can increase the risk of bleeding.

How to manage the interaction:
Taking Paribest 40Mg/0.4Ml Inj Pfs with Tirofiban together can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away back pain, numbness, constipation, bleeding, bruises, dizziness, lightheaded, red or black stools, severe headache, weakness, or vomiting blood. Do not discontinue any medications without consulting a doctor.
EnoxaparinOmacetaxine mepesuccinate
Severe
How does the drug interact with Paribest 40Mg/0.4Ml Inj Pfs:
Combining Paribest 40Mg/0.4Ml Inj Pfs with Omacetaxine mepesuccinate can increase the risk or severity of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Paribest 40Mg/0.4Ml Inj Pfs and Omacetaxine mepesuccinate, but it can be taken if prescribed by a doctor. If you notice any symptoms like bleeding, bruising, dizziness, or severe headache, it's crucial to contact a doctor right away. They can help you address these concerns and prevent any serious complications. Do not stop using any medications without talking to a doctor.
EnoxaparinPhenylbutazone
Severe
How does the drug interact with Paribest 40Mg/0.4Ml Inj Pfs:
Taking Paribest 40Mg/0.4Ml Inj Pfs together with phenylbutazone can increase the risk or severity of bleeding complications.

How to manage the interaction:
Although taking Paribest 40Mg/0.4Ml Inj Pfs and Phenylbutazone together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these signs like difficulty with bleeding, bleeding, bruising, swelling, throwing up, headache, feeling lightheaded, weakness, or blood in your urine or stools it's important to contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EnoxaparinRuxolitinib
Severe
How does the drug interact with Paribest 40Mg/0.4Ml Inj Pfs:
Taking Paribest 40Mg/0.4Ml Inj Pfs with ruxolitinib can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Paribest 40Mg/0.4Ml Inj Pfs with Ruxolitinib together can result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms like bleeding, bruising, dizziness, severe headaches, black or tarry stools, weakness, and vomiting other symptoms to watch out for include black or tarry stools, weakness, and vomiting. Do not discontinue any medications without consulting a doctor.
EnoxaparinPonatinib
Severe
How does the drug interact with Paribest 40Mg/0.4Ml Inj Pfs:
Combining Paribest 40Mg/0.4Ml Inj Pfs with Ponatinib can increase the risk or severity of bleeding.

How to manage the interaction:
Although taking Paribest 40Mg/0.4Ml Inj Pfs and Ponatinib together can cause an interaction, it can be taken if your doctor has suggested it. If you notice symptoms like severe headaches, vomiting, weakness bleeding, bruising, dizziness, or black stools, it is recommended to contact a doctor right away. Other concerning symptoms. Do not discontinue any medications without consulting a doctor.
EnoxaparinKetorolac
Severe
How does the drug interact with Paribest 40Mg/0.4Ml Inj Pfs:
Taking Paribest 40Mg/0.4Ml Inj Pfs and ketorolac together can increase the risk or severity of bleeding problems.

How to manage the interaction:
Although taking Ketorolac and Paribest 40Mg/0.4Ml Inj Pfs together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A low cholesterol diet and a regular exercise regime complement treatment with Paribest 40Mg/0.4Ml Inj Pfs effectively.
  • As a precautionary measure, you are recommended not to consume alcohol, or junk food items from outside, stick to a freshly prepared home-cooked meal and rest properly for a speedy recovery.
  • And also, trying to replace most of your saturated fats with unsaturated fats can reduce total cholesterol and LDL in a short time.
  • Foods like avocados, olive oil, fatty fish, and nuts contain many heart-healthy unsaturated fats, so eating them regularly is beneficial.
  • Option for foods high in vitamin K (liver, leafy green vegetables, or vegetable oils) as Paribest 40Mg/0.4Ml Inj Pfs may lower Vitamin K in your body.
  • Avoid drinking alcohol as it increases the risk of gastrointestinal ulcer/bleeding.
  • Cranberry juice, grapefruit juice, noni juice, and pomegranate juice may interact with Paribest 40Mg/0.4Ml Inj Pfs and lead to unwanted side effects. Hence try to avoid these juices while taking Paribest 40Mg/0.4Ml Inj Pfs.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Paribest 40Mg/0.4Ml Inj Pfs Substitute

Substitutes safety advice
  • Enoxa-K 60 Injection 0.6 ml

    577.80per tablet
  • Enoxaflo 40 mg Injection 0.4 ml

    423.00per tablet
  • Unox 60Mg/0.6Ml Inj

    536.40per tablet
  • Enoclot 60 mg Injection 0.6 ml

    by AYUR

    573.75per tablet
  • Paribest 60Mg/0.6Ml Inj Pfs

    639.90per tablet
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Alcohol

Caution

Limit intake of alcohol as it may increase the risk of bleeding.

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Pregnancy

Caution

Paribest 40Mg/0.4Ml Inj Pfs is not recommended for use in pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Paribest 40Mg/0.4Ml Inj Pfs.

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Breast Feeding

Caution

Paribest 40Mg/0.4Ml Inj Pfs is not recommended for use in breastfeeding unless clearly necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Paribest 40Mg/0.4Ml Inj Pfs.

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Driving

Safe if prescribed

It does not affect your ability to drive.

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Liver

Caution

If you have a history of liver diseases or pre-existing liver conditions, please inform your doctor before taking this Paribest 40Mg/0.4Ml Inj Pfs. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

If you have a history of kidney diseases or pre-existing kidney conditions, please inform your doctor before taking this Paribest 40Mg/0.4Ml Inj Pfs. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

It is not recommended for treatment in children under 18 years of age as safety and efficacy have not been established.

FAQs

Paribest 40Mg/0.4Ml Inj Pfs is used to prevent or treat blood clots caused by medical conditions, such as unstable angina, after an operation or long periods of bed rest due to illness, after a heart attack, and the formation of blood clots in the dialysis machine tubes.
Paribest 40Mg/0.4Ml Inj Pfs contains Enoxaparin, which is low molecular weight heparin or LMWH. Paribest 40Mg/0.4Ml Inj Pfs works by stopping existing blood clots from getting any bigger. This helps your body to break them down and prevents them from causing you harm. On the other hand, it stops new blood clots from forming in your blood.
Yes, this Paribest 40Mg/0.4Ml Inj Pfs is given based on your age and body weight. If you have low body weight, the chances of increased risk of bleeding are high, so mostly low doses are prescribed by your doctor. You may be monitored closely for signs of clot formation.
No, do not take this Paribest 40Mg/0.4Ml Inj Pfs if you have a stomach ulcer. Please inform your doctor about this condition before receiving it.
Yes, Paribest 40Mg/0.4Ml Inj Pfs may cause bleeding. If you notice purple spots on the skin or unusual bruising, blood in urine, black tarry stools, or unusual bleeding from the gums or nose, please inform your doctor immediately as these are signs of bleeding more easily.
Increases in liver enzymes are the most common side effect with Paribest 40Mg/0.4Ml Inj Pfs. Regular lipid profile tests are recommended to avoid any additional complications.
Paribest 40Mg/0.4Ml Inj Pfs typically starts showing its effect within 1 to 2 hours and it remains in the body for about 12 hours.
No, Paribest 40Mg/0.4Ml Inj Pfs dosage should be given exactly as prescribed by the doctor.
Paribest 40Mg/0.4Ml Inj Pfs contains Enoxaparin as it active ingredient.
Paribest 40Mg/0.4Ml Inj Pfs is mostly prescribed for angina (chest pain), deep vein thrombosis (blood clot in veins) and as a post-surgery precautionary step.
Yes, there are many substitutes available in the market. However, please note that all these substitutes have the same composition and thus should be administered with the same set of precautions.
Paribest 40Mg/0.4Ml Inj Pfs will be administered by a doctor or nurse in the hospital or clinic. Do not self-administer.
Bleeding is one of the side effects of Paribest 40Mg/0.4Ml Inj Pfs in some individuals. If you experience any kind of unusual symptoms such as black tarry stool, unusual bleeding, etc., inform the doctor immediately.
The side effects of Paribest 40Mg/0.4Ml Inj Pfs include bleeding, increases in liver enzymes, bruise more easily than usual, pink patches on your skin, skin rash (hives, urticaria), itchy red skin, pain or bruising at the injection site and headache. If these side effects persist or worsen, please inform your doctor.
The dose and duration of Paribest 40Mg/0.4Ml Inj Pfs is prescribed by a doctor based on the underlying condition and the patient’s response to the treatment.
Paribest 40Mg/0.4Ml Inj Pfs is injected beneath the skin. Fix the medicine dose and make a fold by pinching the skin of your stomach between your finger and thumb. After cleansing the area, hold the syringe like a pencil and insert the full length of the needle into the skin fold. Inject Paribest 40Mg/0.4Ml Inj Pfs and discard the syringe as instructed by your doctor. Follow the instructions given by the doctor strictly. In case of any doubt or any reactions associated with the medicine, contact your doctor.
Tell your doctor if you have a heart valve fitted or have high blood pressure, gastric ulcer, kidney problems or diabetes. Also, let your doctor know if you ever had a reaction to heparin or had a recent stroke, spinal or brain surgery. The chances of complications and side effects increase in these conditions.
Store Paribest 40Mg/0.4Ml Inj Pfs below 25°C. Do not freeze. Keep it out of reach and sight of children.
Yes, Paribest 40Mg/0.4Ml Inj Pfs is used in the treatment of heart attack and chest pain once the patient has received the standard treatment. It is administered along with another blood thinner like aspirin. As it is a blood thinner, it prevents the blood from clotting and prevents any further episodes and complications.
Yes, you can push the air bubbles into the injection site. Removing the air bubbles causes loss of the medicine thereby changing the prescribed dose.

Country of origin

India

Manufacturer/Marketer address

3709, G.I.D.C., Phase Iv, Vatva, Ahmedabad 382 445 , Gujarat., India.
Other Info - PAR1032

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