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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:39 PM IST
Panzynorm HS Tablet is used for the treatment of exocrine pancreatic insufficiency (pancreatin enzyme deficiency) due to cystic fibrosis (an inherited disorder that damages the lungs and digestive system), chronic pancreatitis (inflammation of the pancreas), or other conditions. It contains Pancreatin, which help in the digestion of food. It mixes thoroughly with the food and helps in digestion as it passes through the gut. In some cases, it may cause certain common side effects such as nausea, mild stomach pain, diarrhoea, and mild skin rash. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Composition

PANCREATIN-360MG

Manufacturer/Marketer

Zydus Cadila

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Panzynorm HS Tablet

Panzynorm HS Tablet is a pancreatic enzyme supplement indicated for the treatment of exocrine pancreatic insufficiency (pancreatin enzyme deficiency) due to cystic fibrosis (an inherited disorder that damages the lungs and digestive system), chronic pancreatitis (inflammation of the pancreas), or other conditions. Exocrine pancreatic insufficiency occurs in people whose bodies do not make enough of their own enzymes.

Panzynorm HS Tablet contains Pancreatin, which is a combination of digestive enzymes such as porcine-derived lipases, proteases, and amylases. These enzymes help in the digestion of food. Panzynorm HS Tablet mixes thoroughly with the food and helps in digestion as it passes through the gut.

You are advised to take Panzynorm HS Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Panzynorm HS Tablet may cause certain common side-effects such as nausea, mild stomach pain, diarrhoea, and mild skin rash. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Inform your doctor before taking Panzynorm HS Tablet if you have gout, asthma, or any disease condition. Consult your doctor before taking Panzynorm HS Tablet if you are pregnant or breastfeeding. Panzynorm HS Tablet may cause dizziness, so drive with caution. It is unknown whether alcohol interacts with Panzynorm HS Tablet ; please consult your doctor if you have any concerns regarding this. Panzynorm HS Tablet can be given to children if prescribed by the doctor; the dose depends upon the child’s age and body weight.

Uses of Panzynorm HS Tablet

Treatment of Pancreatic insufficiency (pancreatin enzyme deficiency).

Medicinal Benefits

Panzynorm HS Tablet is a pancreatic enzyme supplement indicated for the treatment of exocrine pancreatic insufficiency (pancreatin enzyme deficiency) due to cystic fibrosis (an inherited disorder that damages the lungs and digestive system), chronic pancreatitis (inflammation of the pancreas), or other conditions. Pancreatin is a combination of digestive enzymes such as porcine-derived lipases, proteases, and amylases. These enzymes help in the digestion of food. Panzynorm HS Tablet mixes thoroughly with the food and helps in digestion as it passes through the gut. Panzynorm HS Tablet may also be used to treat steatorrhea (oily, smelly stools due to lack of fat absorption). 

Directions for Use

Capsule/Minimicrospheres: Swallow it as a whole with a glass of water; do not chew or crush the capsule/minimicrospheres.Granules: Mix the granules in apple/pineapple/orange juice or yoghurt; swallow the mixture directly without chewing. Do not mix pancreatin with very hot food/liquids.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Panzynorm HS Tablet

  • Nausea
  • Mild stomach pain 
  • Diarrhoea
  • Mild skin rash

Drug Warnings

Do not take Panzynorm HS Tablet if you are allergic to pork (pig), cow or buffalo products. Consult your doctor if you experience stomach pain, swelling, constipation, and vomiting as patients taking Panzynorm HS Tablet with cystic fibrosis may develop a rare bowel condition called fibrosing colonopathy. Inform your doctor before taking Panzynorm HS Tablet if you have gout, asthma, or any disease condition. Consult your doctor before taking Panzynorm HS Tablet if you are pregnant or breastfeeding. Panzynorm HS Tablet may cause dizziness, so drive with caution. It is unknown whether alcohol interacts with Panzynorm HS Tablet ; please consult your doctor if you have any concerns regarding this. Panzynorm HS Tablet can be given to children if prescribed by the doctor; the dose depends upon the child’s age and body weight.

Drug Interactions

Drug-Drug Interactions: Panzynorm HS Tablet may interact with calcium, iron, and calcium supplements. 

Drug-Food Interactions: No interaction found/established. 

Drug-Disease Interactions: No interaction found/established. 

Drug-Drug Interactions Checker List

  • CALCIUM
  • CALCITRIOL
  • FERROUS SULPHATE
  • IRON

Habit Forming

No

Diet & Lifestyle Advise

  • Eat small portions of meals 3-5 times a day as larger meals make the digestive system work overtime.

  • Include diet rich in fruits and vegetables.

  • Avoid processed, deep-fried foods as they are hard to digest.

  • Maintain a balanced diet which includes proteins, carbohydrates, and fats. 

  • Stay hydrated by drinking enough water as it helps the digestive system to function smoothly.

  • Avoid highly processed foods which contain trans-fat, hydrogenated fats, and saturated fats. Instead of include foods containing monounsaturated, polyunsaturated and omega-3 fatty acids. Include olive oil, peanut oil, seeds, nuts, salmon, and tuna fish as they contain healthy fats

  • Avoid foods rich in fibre such as brown rice, barley, lentils, and peas as they might interfere with the enzyme activity.

  • Avoid or limit alcohol consumption as it can cause increased damage to the pancreas.

Special Advise

  • Try to avoid taking an antacid within 1 hour before or after you take Panzynorm HS Tablet . Simultaneous use of antacids containing calcium carbonate and/or magnesium hydroxide may lead to pancreatin deficiency. 

Disease/Condition Glossary

Exocrine pancreatic insufficiency: Pancreas play an important role in the digestion of food. It produces enzymes which help in the breakdown of food and absorption of nutrients. Exocrine pancreatic insufficiency occurs in people whose bodies do not make enough of their own enzymes. This leads to the inability of proper food digestion due to the pancreas' lack of a digestive enzyme. Exocrine pancreatic insufficiency could occur due to various conditions such as cystic fibrosis (an inherited disorder that damages the lungs and digestive system), pancreatitis (inflammation of the pancreas), diabetes, celiac disease (inability to digest gluten), pancreatic cancer, inflammatory bowel disease, Zollinger-Ellison disease, pancreatic or stomach surgery. Exocrine pancreatic insufficiency symptoms include abdominal pain, bloating, diarrhoea, flatulence, weight loss, and steatorrhea (loose, fatty, smelly stools). 

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Alcohol

Caution

It is unknown whether alcohol interacts with Panzynorm HS Tablet . Please consult your doctor if you have any concerns regarding this.

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Pregnancy

Caution

Panzynorm HS Tablet belongs to pregnancy category C. Consult your doctor before taking Panzynorm HS Tablet if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Panzynorm HS Tablet passes into breast milk. Consult your doctor before taking Panzynorm HS Tablet ; your doctor will decide whether Panzynorm HS Tablet can be taken by breastfeeding mothers or not.

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Driving

Safe if prescribed

Panzynorm HS Tablet does not affect your ability to drive. However, Panzynorm HS Tablet may cause dizziness. So not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor before taking Panzynorm HS Tablet if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Panzynorm HS Tablet if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

Panzynorm HS Tablet can be given to children if prescribed by the doctor. The dose depends upon the child’s age and body weight.

Country of origin

INDIA

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads, Ahmedabad – 380015, Gujarat, India.
Other Info - PAN0834

Author Details

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FAQs

Panzynorm HS Tablet is used to treat Pancreatic insufficiency (pancreatin enzyme deficiency).
Panzynorm HS Tablet contains ‘pancreatin enzymes’ breakdown food and converts it into energy. Panzynorm HS Tablet is a combination of amylase (to digest starch), protease (to digest protein) and lipase (to digest fat). Thus, together it fulfils the digestive enzymes requirements in the pancreatitis conditions (inflammation of the pancreas), pancreatic cancer, post-surgery of the pancreas, and steatorrhea (loose fatty stool due to poor fat absorption). Â
Panzynorm HS Tablet might interfere with the absorption and reduce the effectiveness of folic acid and iron. To prevent this, maintain a minimum gap between both.
Diarrhoea might be a side-effect of Panzynorm HS Tablet . Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience watery diarrhoea or if you find blood in stools. Do not take anti-diarrhoeal medicine on your own.
Mixing Panzynorm HS Tablet with non-acidic food or liquids, chewing or crushing may cause irritation in the mouth. It might also change the way Panzynorm HS Tablet works in the body. Do not hold Panzynorm HS Tablet or its contents in your mouth.
To treat your condition effectually continue taking Panzynorm HS Tablet for as long as your doctor has prescribed it. Many patients will need to take Panzynorm HS Tablet for the rest of their lives. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Panzynorm HS Tablet .
Pancreatin is a pancreatic enzyme derived from the pancreatic organs of pigs used for food. Consult your doctor before taking Panzynorm HS Tablet if you are allergic to the pig (pork), cow products or buffalo products.
Panzynorm HS Tablet may cause side effects such as nausea, mild stomach pain, diarrhoea, and mild skin rash. If the side effects persist or worsen, consult the doctor.
Panzynorm HS Tablet is safe to be used in children if prescribed by the doctor. The dose depends upon the child’s age and body weight.
Take Panzynorm HS Tablet during or immediately after eating a meal or a snack and drink plenty of water.
Panzynorm HS Tablet is safe to be taken if prescribed by the doctor. Do not take Panzynorm HS Tablet if you are allergic to any of its ingredients, pig or pork products.
Panzynorm HS Tablet should be swallowed as a whole with water. Drink plenty of liquid every day.
Include fruits, vegetables, whole grains, lean meats, poultry without skin, fish, yoghurt, cheese, and non-fat/low-fat milk. Avoid high-fat, deep-fried, and buttered foods.

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