PALOZAC 0.50MG TABLET belongs to a class of drugs called antiemetics used to prevent nausea and vomiting during chemotherapy. Nausea is a feeling of uneasiness of the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

PALOZAC 0.50MG TABLET contains Palonosetron, which works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone—CTZ) in the brain. Thus, it prevents nausea and vomiting.

Take PALOZAC 0.50MG TABLET as prescribed by your doctor. You are advised to take PALOZAC 0.50MG TABLET for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience diarrhoea, constipation, dizziness or headache. Most of these side effects of PALOZAC 0.50MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to PALOZAC 0.50MG TABLET or any other medicines, please tell your doctor. PALOZAC 0.50MG TABLET is not recommended for children. If you are pregnant or breastfeeding, please inform your doctor before taking PALOZAC 0.50MG TABLET. Drive only if you are alert as PALOZAC 0.50MG TABLET may cause tiredness or dizziness. You are recommended to avoid heavy meals and take small nourishing snacks throughout the day. Drink plenty of water to avoid dehydration.

PALOZAC 0.50MG TABLET contains Palonosetron, which blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone—CTZ) in the brain. Thus, it prevents nausea and vomiting during chemotherapy.

• Diarrhoea
• Constipation
• Dizziness
• Headache

If you are allergic to PALOZAC 0.50MG TABLET or any other medicines, please tell your doctor. The oral form is not recommended for children. However, the injection may be given to children above one month as advised by a doctor. If you are pregnant or breastfeeding, please inform your doctor before taking PALOZAC 0.50MG TABLET. Drive only if you are alert, as PALOZAC 0.50MG TABLET may cause tiredness or dizziness. You are recommended to avoid heavy meals and take small nourishing snacks throughout the day. Drink plenty of water to avoid dehydration.

Drug-Drug Interaction: PALOZAC 0.50MG TABLET may interact with antidepressants (citalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, escitalopram, duloxetine, venlafaxine), heart-related drugs or high blood pressure (quinidine, amiodarone, nicardipine), antibiotics (moxifloxacin, erythromycin), antiemetic (domperidone), antipsychotic drugs (thioridazine, quetiapine, chlorpromazine, haloperidol).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have blocked bowel, repeated constipation, heart problems or imbalance of potassium and magnesium in the blood, inform your doctor before taking PALOZAC 0.50MG TABLET.

• CITALOPRAM
• FLUOXETINE
• FLUVOXAMINE
• PAROXETINE
• SERTRALINE
• ESCITALOPRAM
• DULOXETINE
• VENLAFAXINE
• QUINIDINE
• AMIODARONE
• NICARDIPINE
• MOXIFLOXACIN
• ERYTHROMYCIN
• DOMPERIDONE
• THIORIDAZINE
• QUETIAPINE
• CHLORPROMAZINE
• HALOPERIDOL

• Eat a healthy and low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating over sweet food and include more salty food, especially if you have been vomiting.
• Also, if you like to vomit at a specific time, avoid eating your favourite food at that particular time as your taste for that food may get turned off.
• Drink any other liquid at least 30 minutes after eating food.
• If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else do cooking or use prepared food from the freezer.

Nausea and vomiting: Nausea is a feeling of uneasiness of the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth. In short, nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). There is a receptor located in our brain known as the chemoreceptor zone (CTZ) that controls vomiting.