Palonosar Injection belongs to a class of drugs called antiemetics used to prevent nausea and vomiting during chemotherapy. Nausea is a feeling of uneasiness of the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

Palonosar Injection contains Palonosetron which works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.

Palonosar Injection will be administered by a healthcare professional; do not self-administer. In some cases, you may experience diarrhoea, constipation, dizziness or headache. Most of these side effects of Palonosar Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Palonosar Injection or any other medicines, please tell your doctor. Palonosar Injection may be given to children above 1 month in doses as advised by a doctor based on the child's body weight. If you are pregnant or breastfeeding, please inform your doctor before taking Palonosar Injection. Drive only if you are alert as Palonosar Injection may cause tiredness or dizziness. You are recommended to avoid heavy meals and take small nourishing snacks throughout the day. Drink plenty of water to avoid dehydration.

Palonosar Injection contains Palonosetron which blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting during chemotherapy.

• Diarrhoea
• Constipation
• Dizziness
• Headache

If you are allergic to Palonosar Injection or any other medicines, please tell your doctor. Palonosar Injection may be given to children above 1 month in doses as advised by a doctor based on the child's body weight. If you are pregnant or breastfeeding, please inform your doctor before taking Palonosar Injection. Drive only if you are alert as Palonosar Injection may cause tiredness or dizziness. You are recommended to avoid heavy meals and take small nourishing snacks throughout the day. Drink plenty of water to avoid dehydration.

Drug-Drug Interaction: Palonosar Injection may interact with antidepressants (citalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, escitalopram, duloxetine, venlafaxine), heart-related drugs or high blood pressure (quinidine, amiodarone, nicardipine), antibiotics (moxifloxacin, erythromycin), antiemetic (domperidone), antipsychotic drugs (thioridazine, quetiapine, chlorpromazine, haloperidol).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have blocked bowel, repeated constipation, heart problems or imbalance of potassium and magnesium in the blood, inform your doctor before taking Palonosar Injection.

• CITALOPRAM
• FLUVOXAMINE
• PAROXETINE
• SERTRALINE
• ESCITALOPRAM
• DULOXETINE
• VENLAFAXINE
• QUINIDINE
• AMIODARONE
• NICARDIPINE
• MOXIFLOXACIN
• ERYTHROMYCIN
• DOMPERIDONE
• THIORIDAZINE
• QUETIAPINE
• CHLORPROMAZINE
• HALOPERIDOL

• Eat a healthy diet and a low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.
• Also, if you like to vomit at a specific time, avoid eating your favourite food at that particular time as your taste for that food may get turned off.
• Drink any other liquid at least 30 minutes after eating food.
• If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

Nausea and vomiting: Nausea is a feeling of uneasiness of the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth. In short, nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). There is a receptor located in our brain known as the chemoreceptor zone (CTZ) that controls vomiting.