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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Palnon 0.25 mg Injection 5 ml is used to prevent nausea and vomiting during chemotherapy. It contains Palonosetron, which blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone) located in the brain. Thus, it prevents nausea and vomiting. Common side effects of Palnon 0.25 mg Injection 5 ml are diarrhoea, constipation, dizziness or headache.
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Composition :

PALONOSETRON-0.25MG

Manufacturer/Marketer :

Medion Biotech Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Palnon 0.25 mg Injection 5 ml

Palnon 0.25 mg Injection 5 ml belongs to a class of drugs called antiemetics used to prevent nausea and vomiting during chemotherapy. Nausea is a feeling of uneasiness of the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

Palnon 0.25 mg Injection 5 ml contains Palonosetron which works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.

Palnon 0.25 mg Injection 5 ml will be administered by a healthcare professional; do not self-administer. In some cases, you may experience diarrhoea, constipation, dizziness or headache. Most of these side effects of Palnon 0.25 mg Injection 5 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Palnon 0.25 mg Injection 5 ml or any other medicines, please tell your doctor. Palnon 0.25 mg Injection 5 ml may be given to children above 1 month in doses as advised by a doctor based on the child's body weight. If you are pregnant or breastfeeding, please inform your doctor before taking Palnon 0.25 mg Injection 5 ml. Drive only if you are alert as Palnon 0.25 mg Injection 5 ml may cause tiredness or dizziness. You are recommended to avoid heavy meals and take small nourishing snacks throughout the day. Drink plenty of water to avoid dehydration.

Uses of Palnon 0.25 mg Injection 5 ml

Treatment of Nausea and vomiting

Directions for Use

Palnon 0.25 mg Injection 5 ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Palnon 0.25 mg Injection 5 ml contains Palonosetron which blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting during chemotherapy.

How Palnon 0.25 mg Injection 5 ml Works

Palnon 0.25 mg Injection 5 ml contains Palonosetron which works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Palnon 0.25 mg Injection 5 ml

  • Diarrhoea
  • Constipation
  • Dizziness
  • Headache

What if I have taken an overdose of Palnon 0.25 mg Injection 5 ml

As Palnon 0.25 mg Injection 5 ml is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Palnon 0.25 mg Injection 5 ml may cause bluish colour of the fingernails, lips, skin, palms, or nail beds, collapse, gasping to breathe, paleness of the skin, and seizures.

Drug Warnings

If you are allergic to Palnon 0.25 mg Injection 5 ml or any other medicines, please tell your doctor. Palnon 0.25 mg Injection 5 ml may be given to children above 1 month in doses as advised by a doctor based on the child's body weight. If you are pregnant or breastfeeding, please inform your doctor before taking Palnon 0.25 mg Injection 5 ml. Drive only if you are alert as Palnon 0.25 mg Injection 5 ml may cause tiredness or dizziness. You are recommended to avoid heavy meals and take small nourishing snacks throughout the day. Drink plenty of water to avoid dehydration.

Drug-Drug Interactions

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PalonosetronZiprasidone
Critical
PalonosetronVenlafaxine
Severe

Drug-Drug Interactions

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PalonosetronZiprasidone
Critical
How does the drug interact with Palnon 0.25 mg Injection 5 ml:
Combining Palnon 0.25 mg Injection 5 ml with Ziprasidone can increase the risk of side effects.

How to manage the interaction:
Taking Ziprasidone with Palnon 0.25 mg Injection 5 ml is not recommended, please consult your doctor before taking it.
PalonosetronVenlafaxine
Severe
How does the drug interact with Palnon 0.25 mg Injection 5 ml:
When venlafaxine is taken with Palnon 0.25 mg Injection 5 ml, it can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Although there is a possible interaction between Venlafaxine and Palnon 0.25 mg Injection 5 ml, you can take these medicines together if prescribed by a doctor. However, if you experience any of the following symptoms: confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhoea, seek immediate medical attention. Do not discontinue any medications without consulting a doctor.
PalonosetronBuspirone
Severe
How does the drug interact with Palnon 0.25 mg Injection 5 ml:
Using Buspirone together with Fenfluramine can increase the risk of a serious condition called serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is a chemical that plays a role in overall wellbeing and especially a mood stabilizer).

How to manage the interaction:
Co- administration of buspirone along with Palnon 0.25 mg Injection 5 ml can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
PalonosetronDoxepin
Severe
How does the drug interact with Palnon 0.25 mg Injection 5 ml:
The combined use of Palnon 0.25 mg Injection 5 ml and doxepin can increase the risk of serotonin syndrome(A condition in which a chemical called serotonin builds up in your body) and increase the risk of irregular heart rhythms.

How to manage the interaction:
Co-administration of Palnon 0.25 mg Injection 5 ml and Doxepin can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, diarrhoea, sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
PalonosetronAmitriptyline
Severe
How does the drug interact with Palnon 0.25 mg Injection 5 ml:
Combining Palnon 0.25 mg Injection 5 ml with Amitriptyline can increase the risk of serotonin syndrome.(A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Although using Palnon 0.25 mg Injection 5 ml and Amitriptyline together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken amitriptyline. Do not discontinue any medications without consulting a doctor.
PalonosetronAmiodarone
Severe
How does the drug interact with Palnon 0.25 mg Injection 5 ml:
Coadministration of Amiodarone with Palnon 0.25 mg Injection 5 ml can lead to or increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Amiodarone with Palnon 0.25 mg Injection 5 ml together is avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PalonosetronVilazodone
Severe
How does the drug interact with Palnon 0.25 mg Injection 5 ml:
When Vilazodone is taken with Palnon 0.25 mg Injection 5 ml, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Vilazodone and Palnon 0.25 mg Injection 5 ml, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-call a doctor right away. Do not stop using any medications without a doctor's advice.
PalonosetronHydroxychloroquine
Severe
How does the drug interact with Palnon 0.25 mg Injection 5 ml:
The combined use of Palnon 0.25 mg Injection 5 ml and Hydroxychloroquine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of palponosetron and Hydroxychloroquine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
PalonosetronPentazocine
Severe
How does the drug interact with Palnon 0.25 mg Injection 5 ml:
Taking Palnon 0.25 mg Injection 5 ml with Pentazocine may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a possible interaction between Pentazocine and Palnon 0.25 mg Injection 5 ml, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
PalonosetronClomipramine
Severe
How does the drug interact with Palnon 0.25 mg Injection 5 ml:
The combined use of Palnon 0.25 mg Injection 5 ml with clomipramine can increase the risk of serotonin syndrome (Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body, causing signs and symptoms ranging from mild (shivering and diarrhea) to severe (muscle rigidity, fever, and seizures)).

How to manage the interaction:
Although taking clomipramine and Palnon 0.25 mg Injection 5 ml together can cause an interaction, it can be taken if your doctor has suggested it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and a low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.
  • Also, if you like to vomit at a specific time, avoid eating your favourite food at that particular time as your taste for that food may get turned off.
  • Drink any other liquid at least 30 minutes after eating food.
  • If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Palnon 0.25 mg Injection 5 ml Substitute

Substitutes safety advice
  • Palonoget 0.25 mg Injection 5 ml

    132.30per tablet
  • Palibout 0.25 Injection 5 ml

    33.26per tablet
  • Palmocet 0.25 Injection 5 ml

    130.50per tablet
  • Chepatron 0.25mg Injection

    128.57per tablet
  • Palostar 0.25mg Injection

    26.82per tablet
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Alcohol

Caution

The interaction of alcohol with Palnon 0.25 mg Injection 5 ml is unknown. Please consult a doctor before consuming alcohol with Palnon 0.25 mg Injection 5 ml.

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Pregnancy

Consult your doctor

Palnon 0.25 mg Injection 5 ml is given to pregnant women only if the doctor thinks the benefits outweigh the risks. Please inform your doctor if you are pregnant.

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Breast Feeding

Consult your doctor

Please inform your doctor before taking Palnon 0.25 mg Injection 5 ml if you are breastfeeding. Palnon 0.25 mg Injection 5 ml is given to breastfeeding women only if the doctor thinks the benefits are greater than the risks.

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Driving

Caution

Palnon 0.25 mg Injection 5 ml may cause tiredness or dizziness in some people. Therefore, avoid driving or operating heavy machinery if you feel tired or dizzy after taking Palnon 0.25 mg Injection 5 ml.

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Liver

Safe if prescribed

Palnon 0.25 mg Injection 5 ml may be safe to use in patients with liver problems if prescribed by a doctor. However, if you have any concerns regarding this, please discuss them with your doctor.

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Kidney

Safe if prescribed

Palnon 0.25 mg Injection 5 ml may be safe to use in patients with kidney problems if prescribed by a doctor. However, if you have any concerns regarding this, please discuss them with your doctor.

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Children

Caution

Palnon 0.25 mg Injection 5 ml may be given to children above 1 month in doses as advised by a doctor based on the child's body weight.

FAQs

Palnon 0.25 mg Injection 5 ml is used to treat nausea and vomiting.
Palnon 0.25 mg Injection 5 ml contains Palonosetron which works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.
You are not recommended to take erythromycin with Palnon 0.25 mg Injection 5 ml as it may increase the risk of severe irregular heart rhythm. However, please consult your doctor before taking other medicines with Palnon 0.25 mg Injection 5 ml.
Palnon 0.25 mg Injection 5 ml may cause constipation as a side effect. It is not necessary for everyone taking Palnon 0.25 mg Injection 5 ml to experience this side effect. However, if the condition persists or worsens, please consult a doctor.
Palnon 0.25 mg Injection 5 ml should be used with caution in patients suffering from heart problems as it may worsen the condition. Therefore, inform your doctor if you have any heart problems before taking have Palnon 0.25 mg Injection 5 ml so that the dose may be adjusted appropriately.

Country of origin

India

Manufacturer/Marketer address

409, 4Th Floor, Devika Tower, Chander Nagar, Surya Nagar, Ghaziabad-201011, Uttar Pradesh, India
Other Info - PAL0291

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