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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:38 PM IST
Palicalm 6mg Tablet ER is used to treat schizophrenia and manic depression (or bipolar disorder). It contains Paliperidone which works by blocking the effects of chemical messengers in the brain (dopamine and serotonin), thereby helping improve mood, behaviour and thoughts. This medicine may sometimes cause side effects such as sleepiness, depression, anxiety, restlessness, shortness of breath, abdominal pain, dizziness and headache. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Composition

PALIPERIDONE-6MG

Manufacturer/Marketer

Reliance Formulation Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Palicalm 6mg Tablet ER

Palicalm 6mg Tablet ER belongs to a group of medicines called 'antipsychotics' used to treat schizophrenia and manic depression (or bipolar disorder). Palicalm 6mg Tablet ER also treats short-term treatment of long-term aggression in people with Alzheimer's dementia and mentally disabled children. Schizophrenia is a mental condition in which the person may feel, hear or see things that are not there, believe things that are not true, or feel unusually suspicious or confused. Manic depression, or bipolar disorder, is a severe brain disorder in which a person experiences extreme mood swings (variance in thinking) and frequent mood and behaviour changes. 

Palicalm 6mg Tablet ER contains 'Paliperidone' that works by blocking the effects of chemical messengers in the brain (i.e., dopamine and serotonin), thereby helping improve mood, behaviour and thoughts. Palicalm 6mg Tablet ER elevates the symptoms of the disease and prevents them from returning. 

Take Palicalm 6mg Tablet ER as your doctor has prescribed it. In some cases, you may experience common side effects such as Parkinsonism, difficulty sleeping, sleepiness, depression, anxiety, restlessness, shortness of breath, abdominal pain, dizziness and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Palicalm 6mg Tablet ER for as long as your doctor has prescribed. Do not take Palicalm 6mg Tablet ER if you are pregnant or breastfeeding unless prescribed. Palicalm 6mg Tablet ER causes drowsiness and dizziness, do not drive unless you are alert. Palicalm 6mg Tablet ER can be given to children if prescribed by the doctor for treating conduct disorder. Palicalm 6mg Tablet ER should not be given to children for treating schizophrenia or mania. Avoid consuming alcohol with Palicalm 6mg Tablet ER as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Palicalm 6mg Tablet ER

Treatment of Schizophrenia, Manic depression (bipolar disorder).

Medicinal Benefits

Palicalm 6mg Tablet ER belongs to a group of medicines called antipsychotics used to treat schizophrenia in adults and children above 13 years old and bipolar disorder in children at least ten years of age. Palicalm 6mg Tablet ER also treats short-term treatment of long-term aggression in people with Alzheimer's dementia and mentally disabled children. Palicalm 6mg Tablet ER improves mood and behaviour in people with an imbalance of chemicals known as neurotransmitters in their brains. Thus, Palicalm 6mg Tablet ER relieves psychotic symptoms like delusions, hallucinations, confusion, disturbing thoughts and lack of self-awareness. Besides this, it also treats irritability symptoms in children with autism who are 5-16 years of age.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Palicalm 6mg Tablet ER

  • Difficulty in sleeping
  • Sleepiness
  • Depression
  • Anxiety
  • Restlessness
  • Shortness of breath
  • Abdominal pain
  • Dizziness
  • Headache 

Drug Warnings

Do not take Palicalm 6mg Tablet ER if you are allergic to Paliperidone or any of its contents. Do not take Palicalm 6mg Tablet ER if you are pregnant or breastfeeding unless prescribed. Palicalm 6mg Tablet ER causes drowsiness and dizziness, do not drive unless you are alert. Palicalm 6mg Tablet ER can be given to children above ten years if prescribed by the doctor for treating a mental condition like schizophrenia and bipolar disorder. Avoid consuming alcohol along with Palicalm 6mg Tablet ER as it could lead to increased drowsiness and dizziness. Rise slowly from sitting or lying position as Palicalm 6mg Tablet ER causes orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing). Inform your doctor before taking Palicalm 6mg Tablet ER if you have diabetes, as Palicalm 6mg Tablet ER can cause an increase in blood sugar levels. Palicalm 6mg Tablet ER may not be suitable for people with a history of prolactin-dependent breast cancer as Palicalm 6mg Tablet ER increases prolactin levels. Palicalm 6mg Tablet ER should not be used in adults to treat dementia-related psychosis. 

Drug Interactions

Drug-Drug Interactions: Palicalm 6mg Tablet ER may have interaction with medicines used to treat schizophrenia and bipolar disorder (aripiprazole), anxiety disorders (lorazepam, diazepam, alprazolam), depression (citalopram, duloxetine, fluoxetine, escitalopram, trazodone, sertraline), allergy (diphenhydramine, hydroxyzine), mania (divalproex sodium), fits (gabapentin, clonazepam, lamotrigine, pregabalin ), pain (oxycodone, tramadol), asthma (albuterol), psychosis (quetiapine).

Drug-Food Interactions: Palicalm 6mg Tablet ER may interact with alcohol, obesity, and high cholesterol levels.

Drug-Disease Interactions: Palicalm 6mg Tablet ER may have interactions with dementia (memory loss), CNS depression, liver disease, seizures, low blood pressure, diabetes, lipid alterations, weight gain, parkinsonism, acute alcohol intoxication, neuroleptic malignant syndrome (occurs due to reaction with anti-psychotic drugs), Tardive dyskinesia (repetitive, involuntary movements), irregular heartbeat (with QT interval prolongation), kidney impairment/disease, blood abnormalities, lipid alterations, Priapism (prolonged erection of the penis), and hyperprolactinemia (higher levels of prolactin in the blood).

Drug-Drug Interactions Checker List

  • ARIPIPRAZOLE
  • LORAZEPAM
  • DIAZEPAM
  • ALPRAZOLAM
  • CITALOPRAM
  • DULOXETINE
  • FLUOXETINE
  • ESCITALOPRAM
  • TRAZODONE
  • SERTRALINE
  • DIPHENHYDRAMINE
  • HYDROXYZINE
  • DIVALPROEX SODIUM
  • GABAPENTIN
  • CLONAZEPAM
  • LAMOTRIGINE
  • PREGABALIN
  • OXYCODONE
  • TRAMADOL
  • ALBUTEROL
  • QUETIAPINE

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga.
  • Follow a regular sleep pattern.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Special Advise

While taking Palicalm 6mg Tablet ER, you may become more sensitive to extreme temperature conditions (like too hot or too cold), so it is advisable to avoid getting too hot or too hot or dehydrated, especially during summer. Drink plenty of fluid and water to cope with this condition. 

Disease/Condition Glossary

Schizophrenia: It is a condition in which the person may see, hear or feel things that are not there, believe things that are not true, or feel unusually suspicious or confused. Symptoms include hallucinations, delusions, thought disorders, movement disorders, disorganized thinking, loss of interest, lack of emotions, etc.

Manic depression (bipolar disorder): It is a serious brain disorder in which a person goes through unusual mood changes (mood swings) and frequent changes in his/her behaviour and thinking.

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Palicalm 6mg Tablet ER as it may cause increased drowsiness and lower your blood pressure.

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Pregnancy

Caution

Avoid taking Palicalm 6mg Tablet ER if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Palicalm 6mg Tablet ER can pass into the breastmilk, so it is not safe to breastfeed while taking Palicalm 6mg Tablet ER. Inform your doctor before taking the Palicalm 6mg Tablet ER; your doctor will decide whether the Palicalm 6mg Tablet ER can be taken by breastfeeding mothers or not. Tell your doctor if your baby has symptoms of dizziness or tremor.

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Driving

Unsafe

Palicalm 6mg Tablet ER causes tiredness, dizziness and vision problems. Do not drive or operate machinery without consulting your doctor.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

The safety and efficacy of Palicalm 6mg Tablet ER are not established in children under the age of 18 years.

Country of origin

India
Other Info - PA65593

Author Details

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FAQs

Palicalm 6mg Tablet ER is used to treat schizophrenia and manic depression (or bipolar disorder).
Palicalm 6mg Tablet ER works by balancing the chemical messengers called neurotransmitters and blocking the effect of dopamine and serotonin located in the brain, thereby helps in improving mood, behavior and thoughts.
Palicalm 6mg Tablet ER causes tiredness, dizziness and vision problems. So, it is advisable not to drive or operate machinery without consulting your doctor. It may also lower your blood pressure on sudden standing leading to dizziness, so try to get up easily to avoid this.
Palicalm 6mg Tablet ER may cause an increase in blood glucose (sugar) levels. So, regular monitoring of blood sugar levels is advised while taking Palicalm 6mg Tablet ER. Diabetes patients should consult a doctor before taking Palicalm 6mg Tablet ER.
Yes, orthostatic hypotension could be a side-effect of Palicalm 6mg Tablet ER. Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking; instead, lie down and get up slowly only when you feel better. People taking Palicalm 6mg Tablet ER are advised to regularly monitor their blood pressure levels to avoid such unpleasant events.
Palicalm 6mg Tablet ER may make you sweat less, making you more likely to get heatstroke. Avoid doing things that may cause you to overheat, such as hard work or exercise in hot weather, or using hot tubs. When the weather is hot, drink a lot of fluids and dress lightly.
Dry mouth could be a side-effect of Palicalm 6mg Tablet ER. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.
Palicalm 6mg Tablet ER is known to cause increased mortality in people who are elderly with dementia. So, please inform your doctor if you have dementia; before starting Palicalm 6mg Tablet ER.

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