Pakmine 30mg Injection

Pakmine 30mg Injection is used to treat functional bowel or irritable bowel syndrome (IBS). Pakmine 30mg Injection reduces spasms (sudden involuntary contraction) of the muscles in the stomach and intestines. Irritable bowel syndrome is an intestinal disorder that causes stomach pain, wind, constipation, and diarrhoea.

Pakmine 30mg Injection contains ‘Dicyclomine,’ also known as Dicycloverine. Dicyclomine belongs to the class of ‘anticholinergic/anti-muscarinic agents’ with antispasmodic activity. Pakmine 30mg Injection blocks the activity of acetylcholine (acetylcholine is a neurotransmitter that sends signals to nerve cells) by binding to muscarinic receptors on smooth muscle. This process helps relax smooth muscles and inhibits natural gut movements. Thus, it prevents spasms in the muscles of the stomach and intestine.

Pakmine 30mg Injection will be administered by a healthcare professional. Your doctor will advise the appropriate dose based on your medical condition. It shows common side effects like dizziness, drowsiness, light-headedness, weakness, nervousness, blurred vision, dry mouth, nausea, constipation, and trouble sleeping. These side effects may not occur in every patient using this medication and differ individually. If the side effects persist longer or worsen, please consult your doctor.

Let your doctor know if you are allergic to any medications. Inform your doctor if you have liver, kidney, heart disease, or other medical histories before receiving Pakmine 30mg Injection. Some antacids may inhibit the absorption of Pakmine 30mg Injection; hence, maintain a time gap between the intake of antacids and Pakmine 30mg Injection. Pakmine 30mg Injection may cause blurred vision, dizziness and drowsiness; hence, do not drive or operate machinery until you feel better. Let your doctor know if you are pregnant and breastfeeding before taking Pakmine 30mg Injection. This medicine is not recommended for children below six months of age.

Pakmine 30mg Injection contains ‘Dicyclomine,’ also known as Dicycloverine. Dicyclomine is an ‘anticholinergic/anti-muscarinic agent’ with antispasmodic activity. Pakmine 30mg Injection effectively treats irritable bowel syndrome (IBS). It works by blocking the activity of acetylcholine by binding to muscarinic receptors on smooth muscle. This process helps relax the smooth muscles, inhibits natural gut movements, decreases gastric acid secretion, and controls excessive gastrointestinal secretions. Thus it prevents spasms in the muscles of the stomach and intestines. Pakmine 30mg Injection is also used to relieve stomach cramps, bloating, and pain in the stomach and intestine.

• Dizziness
• Drowsiness
• Light-headedness
• Weakness
• Nervousness
• Blurred vision
• Dry mouth
• Nausea
• Constipation
• Trouble sleeping 

Let your doctor know if you are sensitive to Pakmine 30mg Injection or its inactive components. Pakmine 30mg Injection should be used with caution and only under doctor’s supervision if you have stomach/intestinal problems like slow gut, bowel blockage, acid reflux, ulcerative colitis (inflammation of the colon), and diarrhoea due to intestine surgeries like ileostomy and colostomy. Also, inform your doctor if you have any liver or kidney diseases, urinary retention problems (enlarged prostate), glaucoma, high blood pressure, heart diseases (irregular heart rhythm, coronary artery disease, heart failure), nervous system disorders, and myasthenia gravis (muscle weakness) before using Pakmine 30mg Injection. This medicine may cause blurry vision and sleepiness affecting your mental focus; hence do not drive or operate machinery until you feel better. Tell your doctor if you are pregnant, planning pregnancy, or a nursing mother before being treated with Pakmine 30mg Injection.

Drug-Drug Interaction: Pakmine 30mg Injection may interact with other anticholinergics (amantadine), heart-related drugs (quinidine), opiate pain medicines (meperidine), anti-emetics (metoclopramide), common cold medicines (diphenhydramine), muscle relaxants (cyclobenzaprine), high blood pressure medications (metoprolol), anti-glaucoma agents, and antacids.

Drug-Food Interaction: Avoid fatty foods, alcohol, caffeine and other triggering foods that can worsen your IBS.

Drug-Disease Interaction: Brief your doctor if you have a medical history of stomach/intestinal problems, liver or kidney diseases, glaucoma, high blood pressure, heart diseases, urinary retention problems, nervous system disorders, and myasthenia gravis before using Pakmine 30mg Injection.

• AMANTADINE
• QUINIDINE
• MEPERIDINE
• METOCLOPRAMIDE
• DIPHENHYDRAMINE
• CYCLOBENZAPRINE
• METOPROLOL

• Avoid or limit the intake of alcohol and caffeine.
• Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
• Limit taking high-fibre foods and drinks containing chocolate, milk, alcohol, caffeine, fructose, sorbitol, carbonated drinks, fried, and fatty foods. 
• Do not have large meals at a time; instead, try having small and simpler meals at regular intervals, including fresh fruits and vegetables.
• Practice yoga and recreation techniques to manage your emotional stress.
• If you are lactose intolerant, avoid using dairy products since they can worsen your IBS.
• If you cannot take dairy products, it is advised to include other calcium-rich foods like leafy greens, beans, nuts, and seeds.
• Drink plenty of fluids and dress lightly to prevent heatstroke and dehydration.
• Avoid overly sweating activities like hard exercises and using hot tubs.

Irritable Bowel Syndrome (IBS): IBS is also known as IBS colitis, mucous colitis, spastic colon, nervous colon, and spastic bowel. It is an inflammatory bowel disease that affects the large intestine. Symptoms of an IBS include abdominal pain, bloating, diarrhoea, mucus in stools, wind, constipation, tiredness, anxiety, depression, heartburn, indigestion, and headaches. IBS can be controlled by managing diet, excluding certain intolerant foods, lifestyle and stress. It is commonly found in people in their late teens to early 40s.