Pacroma XL 1% Cream 30 gm is used to prevent allergies, including swelling, itching, redness, heat, and pain caused by certain skin problems such as dermatitis (itchy, swelling of the skin) and eczema (itchy, cracked, swollen or rough skin). Eczema is a condition in which skin patches become inflamed, itchy, cracked and rough. Dermatitis is a skin condition that causes itchy, dry skin or a rash on swollen, reddened skin. 

Pacroma XL 1% Cream 30 gm contains Pimecrolimus works by stopping the immune system from producing chemical substances that may cause eczema. When the skin reacts to any type of allergens, such chemical substances are released normally. It acts inside the skin cells and causes inflammation and characteristic redness and itching of eczema. Pacroma XL 1% Cream 30 gm is used to treat swelling, itching, redness, heat, and pain caused by skin problems such as eczema or atopic dermatitis (itchy, cracked, swollen or rough skin).

Use Pacroma XL 1% Cream 30 gm as prescribed by your doctor. Your doctor will advise the appropriate dose depending on your medical condition. Avoid contact of Pacroma XL 1% Cream 30 gm with nose, mouth, or eyes. If Pacroma XL 1% Cream 30 gm comes into contact with these areas accidentally, rinse it with water thoroughly. Common side effects of Pacroma XL 1% Cream 30 gm include burning, irritation, itching, and redness at the application site. Most of these side effects of Pacroma XL 1% Cream 30 gm do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Avoid using Pacroma XL 1% Cream 30 gm if you are allergic to it. If you are pregnant or a nursing mother, you are advised to consult your doctor before using Pacroma XL 1% Cream 30 gm. Do not use Pacroma XL 1% Cream 30 gm in more than prescribed doses or for a prolonged time as it may cause adverse effects. Avoid consuming alcohol while using Pacroma XL 1% Cream 30 gm as it can make your skin (particularly on your face) flushed or red and feel hot. If you have a weakened immune system (immunocompromised), have erythroderma (redness of almost the entire body), or a skin condition called Netherton’s syndrome (a disorder that affects the skin, hair and immune system) and skin malignancies (tumours), and skin infections (including chickenpox or herpes), inform your doctor before starting Pacroma XL 1% Cream 30 gm.

Pacroma XL 1% Cream 30 gm contains Pimecrolimus is a class of medications called topical calcineurin inhibitors with anti-inflammatory properties, specifically treating inflammation of the skin called atopic dermatitis (eczema). It works by stopping the immune system from producing chemical substances that may cause eczema. When the skin reacts to any type of allergens, such chemical substances are released normally. It acts inside the skin cells and causes inflammation and characteristic redness and itching of eczema. Pacroma XL 1% Cream 30 gm is used to treat swelling, itching, redness, heat, and pain caused by certain skin problems such as eczema or atopic dermatitis (itchy, cracked, swollen, or rough skin) in children (aged 2 years and above), teenagers, and adults. When used to treat early signs and symptoms, Pacroma XL 1% Cream 30 gm can prevent progression to severe flare-ups.

• Mild irritation
• Skin redness
• Burning sensation at the site of application

Do not use Pacroma XL 1% Cream 30 gm to areas of the skin affected by an active viral infection such as cold sores (herpes simplex) or chickenpox. Pacroma XL 1% Cream 30 gm may be associated with an increased risk of severe herpes simplex skin infection (eczema herpeticum). Therefore if you develop painful sores anywhere on your body, tell your doctor immediately. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Pacroma XL 1% Cream 30 gm. Pacroma XL 1% Cream 30 gm is not recommended for children below 2 years of age. Avoid using Pacroma XL 1% Cream 30 gm on open wounds, windburned, sunburned, irritated, or dry skin. Do not cover or wrap the treated area with a bandage unless your doctor advises, as it may cause harmful effects. Avoid contact of topical Pacroma XL 1% Cream 30 gm with nose, mouth, or eyes as it may irritate. If Pacroma XL 1% Cream 30 gm comes in contact with these areas accidentally, rinse with water thoroughly. Avoid smoking or going near naked flames as the fabric (bedding, clothing, dressings) that is in contact with Pacroma XL 1% Cream 30 gm catches fire and burns easily.  If you have a weakened immune system (immunocompromised), have erythroderma (redness of almost the entire body), or a skin condition called Netherton’s syndrome (a disorder that affects the skin, hair and immune system), and skin malignancies (tumours), please inform your doctor before starting Pacroma XL 1% Cream 30 gm. Avoid excessive exposure to sunlight, sun lamps, and tanning beds while using Pacroma XL 1% Cream 30 gm. If you are outdoors after applying Pacroma XL 1% Cream 30 gm, wear loose-fitting clothing, and appropriate sunscreen, and minimise the time you spend in the sun.

Drug-Drug Interaction: Pacroma XL 1% Cream 30 gm may interact with antifungals (fluconazole, itraconazole, ketoconazole), calcium channel blockers (diltiazem, verapamil), antiulcer (cimetidine) antibiotics (clarithromycin, erythromycin, troleandomycin,  metronidazole),  androgenic hormones (danazol),  immunosuppressant  (cyclosporine), HIV protease inhibitors (indinavir, ritonavir, delavirdine), anti-TB (isoniazid), an antidepressant (nefazodone, fluoxetine, fluvoxamine), oral contraceptives (birth control pills).

Drug-Food Interaction: Pacroma XL 1% Cream 30 gm may interact with alcohol. Therefore, avoid the consumption of alcohol with Pacroma XL 1% Cream 30 gm.

Drug-Disease Interaction: If you have skin areas that have cancers or pre-cancers, Netherton's syndrome, skin infections (including chickenpox or herpes), or a weak immune system, inform your doctor before taking Pacroma XL 1% Cream 30 gm.

• FLUCONAZOLE
• ITRACONAZOLE
• KETOCONAZOLE
• DILTIAZEM
• VERAPAMIL
• CIMETIDINE
• CLARITHROMYCIN
• ERYTHROMYCIN
• TROLEANDOMYCIN
• METRONIDAZOLE
• DANAZOL
• CYCLOSPORINE
• INDINAVIR
• RITONAVIR
• DELAVIRDINE
• ISONIAZID
• NEFAZODONE
• FLUOXETINE
• FLUVOXAMINE

• Eat foods rich in quercetin (a flavonoid), such as apples, cherries, broccoli, spinach and blueberries.

• Consuming food rich in probiotics helps in developing the immune system against allergies.
• Limit intake of food that might trigger allergies, such as dairy products, soy, eggs, and nuts.
• Avoid the consumption of foods with excess sugar as it may flare up inflammation.
• Include fruits, vegetables, whole grains, healthy fats and fish in your diet.
• Reducing stress and maintaining a regular sleep pattern would be helpful.
• Avoiding getting in contact with harsh soaps, detergents and rough fabrics.
• Use mild soap while taking baths and prefer warm baths. Avoid harsh products on your skin.
• Do not scratch or pick your skin to avoid getting the affected area infected.

• Avoid contact of Pacroma XL 1% Cream 30 gm with nose, mouth or eyes. In case Pacroma XL 1% Cream 30 gm comes in contact with these areas accidentally, rinse with water thoroughly.

• If you have extensive eczema, you may need to stop using Pacroma XL 1% Cream 30 gm before having any vaccinations. Your doctor will be able to tell you if this is necessary.

• Consult your doctor if no improvement occurs after 2 weeks or if your eczema gets worse.

• Do not apply Pacroma XL 1% Cream 30 gm to areas of the skin affected by an active viral infection such as cold sores (herpes simplex) or chickenpox.

• Do not use Pacroma XL 1% Cream 30 gm without a break for a long time unless told to do so by the doctor.

Atopic dermatitis (eczema): is a skin inflammatory condition characterized by red and itchy rashes. The most common cause of eczema is allergies. Contact with soaps, dyes, chemicals or other irritants may trigger rashes. Avoiding the triggers helps to prevent flare-ups of eczema. Dermatitis is a common skin condition associated with dry, itchy or swollen skin.