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  3. Paclikaas Nab 100 Injection 1's

Paclikaas Nab 100 Injection 1's, Pack of 1 INJECTION
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Paclikaas Nab 100 Injection 1's is used to treat various types of cancers, including ovarian and breast cancer (in advanced/spreading state or after surgery) and advanced-stage non-small cell lung cancer. It contains ‘Paclitaxel’, which stops cell division and prevents certain cancer cell growth. Sometimes, Paclikaas Nab 100 Injection 1's may cause common side effects, such as nausea, vomiting, mild diarrhoea, and joint or muscle pain. It is not recommended for children below 18 years.

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Composition :

PACLITAXEL-100MG

Manufacturer/Marketer :

Anakaas Life Bio Science Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Paclikaas Nab 100 Injection 1's

Paclikaas Nab 100 Injection 1's belongs to the group of anti-cancer medicines called anti-microtubule agents used to treat various types of cancers, including ovarian and breast cancer (in advanced/spreading state or after surgery) and advanced-stage non-small cell lung cancer.

Paclikaas Nab 100 Injection 1's contains ‘Paclitaxel’, which works by stopping cell division and preventing the growth of certain cancer cells.

In some cases, Paclikaas Nab 100 Injection 1's may cause common side effects, such as nausea, vomiting, mild diarrhoea, and joint or muscle pain. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Consult your doctor if you are pregnant, breastfeeding, think you may be pregnant or are planning pregnancy. Paclikaas Nab 100 Injection 1's is not recommended for children below 18 years. Inform your doctor about your health condition and medications to rule out any side effects.

Uses of Paclikaas Nab 100 Injection 1's

Treatment of Ovarian cancer, breast cancer, non-small cell lung cancer

Directions for Use

Paclikaas Nab 100 Injection 1's will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Paclikaas Nab 100 Injection 1's belongs to the group of anti-cancer medicines called anti-microtubule agents used to treat various types of cancers, including ovarian and breast cancer (in advanced/spreading state or after surgery) and advanced-stage non-small cell lung cancer. It may also be used when other treatments have failed or in combination with other treatments. Paclikaas Nab 100 Injection 1's may also be indicated in patients with Kaposi’s sarcoma (cancer that develops from the cells that line lymph or blood vessels) associated with AIDS (Acquired Immuno-Deficiency Syndrome), where other treatments have not been effective. Paclikaas Nab 100 Injection 1's contains ‘Paclitaxel’, which works by preventing the growth of certain cancer cells. 

How Paclikaas Nab 100 Injection 1's Works

Paclikaas Nab 100 Injection 1's contains ‘Paclitaxel’, which works by stopping cell division and preventing the growth of certain cancer cells.

Storage

Store in a cool and dry place away from sunlight
Side effects of Paclikaas Nab 100 Injection
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.
  • If you experience symptoms such as mouth ulcers, redness, difficulty in swallowing or talking, abdominal pain, and painful bowel movements as a drug side effect, consult your doctor as they may adjust the dose if necessary or prescribe alternative medication.
  • Practice good hygiene, such as washing your hands regularly, to prevent infection.
  • Drink plenty of water to keep your mucous membranes hydrated and promote healing.
  • Avoid spicy or acidic foods, which can irritate the mucous membranes and exacerbate inflammation.
  • Increase your intake of omega-3 fatty acids, found in fatty fish, nuts, and seeds, to reduce inflammation.
  • Follow a soft food diet to reduce discomfort and promote healing.
  • Eat well-cooked food to minimize infection risk.
  • Practice good hand hygiene to prevent infections.
  • Avoid crowds and people with illnesses to reduce exposure.
  • Wear a mask when necessary to lower infection risk.
  • Rest adequately to support your body's healing process.
  • Stay hydrated by drinking plenty of water.
  • Regularly monitor blood cell counts for changes.
  • Seek immediate medical help if symptoms like fever, chills, or fatigue occur.
  • Consult your doctor right away if concerning symptoms arise.
  • Follow your doctor's guidance on managing myelosuppression and infection prevention.
  • Your doctor may recommend regular liver function tests (LFT) to monitor liver enzyme levels.
  • To support your liver, eat a healthy diet with lots of fruits, vegetables, lean proteins, and healthy fats.
  • Avoid eating processed meats, sugary foods, and unhealthy fats.
  • Limit your alcohol consumption, since too much can worsen liver function and contribute to high levels of Alkaline Phosphatase (ALP).
  • Stay active with regular exercise, drink plenty of water, and try to avoid harmful chemicals that can damage your liver.
  • Quit smoking to lower the risk of elevated ALP levels.
  • Try taking pain relievers like paracetamol, ibuprofen or naproxen to releve discomfort and pain.
  • Avoid strenuous activities that worsen muscle and joint pain.
  • Do gentle stretching exercises to enhance muscle flexibility and reduce joint pain.
  • Apply cold or warm compresses to your joints and muscles for pain relief.
  • Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • If your joint/muscle pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.

What if I have taken an overdose of Paclikaas Nab 100 Injection 1's

As Paclikaas Nab 100 Injection 1's is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Do not take Paclikaas Nab 100 Injection 1's if you are allergic to any of its components, if your white blood cell or platelet count is very low, if you have a serious uncontrolled infection, and Paclikaas Nab 100 Injection 1's has to be given for the treatment of Kaposi’s sarcoma (cancer that causes lesions in soft tissues), or if you have severe liver problems. Inform your doctor if you have heart disease, abnormal blood cell counts, irregular heartbeat, tingling, numbness, or burning sensation in fingers or toes, visual problems, if you are on radiation therapy, or if you have Kaposi’s sarcoma and have a sore or inflamed mouth. Also, inform your doctor if you are pregnant, breastfeeding, think you are pregnant or planning pregnancy.

Drug-Drug Interactions

verifiedApollotooltip
PaclitaxelBaricitinib
Severe
PaclitaxelClozapine
Severe

Drug-Drug Interactions

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PaclitaxelBaricitinib
Severe
How does the drug interact with Paclikaas Nab 100 Injection:
Coadministration of baricitinib and Paclikaas Nab 100 Injection can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Paclikaas Nab 100 Injection if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
PaclitaxelClozapine
Severe
How does the drug interact with Paclikaas Nab 100 Injection:
Combining Paclikaas Nab 100 Injection with Clozapine can increase the risk of infection.

How to manage the interaction:
Taking Paclikaas Nab 100 Injection with Clozapine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
PaclitaxelTofacitinib
Severe
How does the drug interact with Paclikaas Nab 100 Injection:
Taking Tofacitinib with Paclikaas Nab 100 Injection may increase the risk of infection.

How to manage the interaction:
Although taking Paclikaas Nab 100 Injection and Tofacitinib together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
PaclitaxelRitonavir
Severe
How does the drug interact with Paclikaas Nab 100 Injection:
Taking Ritonavir and Paclikaas Nab 100 Injection may significantly increase the blood levels of Paclikaas Nab 100 Injection.

How to manage the interaction:
Taking Ritonavir with Paclikaas Nab 100 Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. In case of any unusual symptoms, consult a doctor. Do not stop using any medications without talking to a doctor.
PaclitaxelThalidomide
Severe
How does the drug interact with Paclikaas Nab 100 Injection:
Taking thalidomide together with Paclikaas Nab 100 Injection may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Paclikaas Nab 100 Injection together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
PaclitaxelCladribine
Severe
How does the drug interact with Paclikaas Nab 100 Injection:
Combining Cladribine with Paclikaas Nab 100 Injection can increase the risk of developing serious infections.

How to manage the interaction:
Taking Paclikaas Nab 100 Injection with Cladribine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
PaclitaxelEtanercept
Severe
How does the drug interact with Paclikaas Nab 100 Injection:
When Etanercept is used with Paclikaas Nab 100 Injection, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Etanercept and Paclikaas Nab 100 Injection, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
PaclitaxelInfliximab
Severe
How does the drug interact with Paclikaas Nab 100 Injection:
Combining Infliximab with Paclikaas Nab 100 Injection can enhance the breakdown of Paclikaas Nab 100 Injection in the body. This can reduce the treatment outcomes and can increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Paclikaas Nab 100 Injection with Infliximab together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Paclikaas Nab 100 Injection 1's Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Consult your doctor

It is not known if alcohol interacts with this medicine. Please consult your doctor.

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Pregnancy

Unsafe

Paclikaas Nab 100 Injection 1's must not be given during pregnancy unless clearly necessary, as it may cause birth defects. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Paclikaas Nab 100 Injection 1's.

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Breast Feeding

Unsafe

Avoid breastfeeding whilst on treatment with Paclikaas Nab 100 Injection 1's. Do not restart breastfeeding until your doctor tells you it is safe to do so.

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Driving

Caution

Paclikaas Nab 100 Injection 1's may cause dizziness, tiredness, or nausea. Drive or operate heavy machinery only if you are alert.

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Liver

Caution

Do not use Paclikaas Nab 100 Injection 1's if you have severe liver problems. If you have a history of liver disease, inform your doctor before receiving Paclikaas Nab 100 Injection 1's.

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Kidney

Consult your doctor

If you have a history of kidney diseases, inform your doctor before receiving Paclikaas Nab 100 Injection 1's. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

bannner image

Children

Unsafe

Paclikaas Nab 100 Injection 1's is not recommended for children below 18 years due to a lack of data on the safety and effectiveness.

Have a query?

FAQs

Paclikaas Nab 100 Injection 1's is used to treat Ovarian cancer, breast cancer, non-small cell lung cancer.

Paclikaas Nab 100 Injection 1's works by stopping cell division and preventing the growth of certain cancer cells.

Paclikaas Nab 100 Injection 1's might cause sterility which could be permanent. Please talk to your doctor if you have any concerns.

The most common side effect of Paclikaas Nab 100 Injection 1's is hair loss. The hair may grow back after the treatment with Paclikaas Nab 100 Injection 1's is finished. However, consult your doctor if you have any concerns.

Yes, Paclikaas Nab 100 Injection 1's is cytotoxic. It works by interfering with the growth of cancer cells, preventing them from dividing and causing them to die. However, its cytotoxic nature also means it can affect normal, healthy cells, potentially leading to side effects.

Yes, Paclikaas Nab 100 Injection 1's is considered a vesicant. A vesicant is a chemical substance that, if it leaks out of the vein (extravasation), can cause blistering of the skin and surrounding tissues. If Paclikaas Nab 100 Injection 1's accidentally leaks during intravenous (IV) infusion, it may lead to inflammation, blistering, or even tissue necrosis. Your healthcare provider will take precautions to ensure the drug is infused properly and monitor the infusion site for any signs of leakage. If extravasation occurs, the infusion should be stopped immediately, and steps should be taken to minimize the damage.

Paclikaas Nab 100 Injection 1's is an effective cancer treatment with a low risk of cardiac side effects. Your healthcare team will closely monitor your heart function to ensure your safety. They'll watch for any changes in heart rhythms or blood pressure, and work with you to manage any potential issues. With careful monitoring, you can receive this life-saving treatment with confidence.

Paclikaas Nab 100 Injection 1's is a natural product derived from the bark of the Pacific yew tree (Taxus baccata). It is a chemotherapy medication used to treat various cancers, including breast, ovarian, and lung cancer.

The common side effects of Paclikaas Nab 100 Injection 1's include nausea, vomiting, mild diarrhoea, and joint or muscle pain. Not everyone will experience all of these side effects, and they typically resolve once the treatment is stopped. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

No.7/25, Alagiripuram, 1st Street, Bharadeeswarar Colony, Ko dambakkam, Chennai, Kodambakkam, Chennai City Corporation, Chennai, Tamil Nadu.
Other Info - PAC0265

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:44 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.3891.pdf
  2. https://www.hpra.ie/img/uploaded/swedocuments/bc90e8f4-7d4f-46f8-a688-85f51b83406b.pdf
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