P-Zole ISR Capsule is a combination medicine used to treat acidity, GERD (gastro-oesophagal reflux disease), and peptic ulcers. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). Peptic ulcers are sores that develop on the inner lining of the intestine and stomach.

P-Zole ISR Capsule is a combination of two drugs: Pantoprazole and Itopride. Pantoprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Itopride works by accelerating gastric emptying and improves gastric sensitivity and tension. It also has anti-emetic action. Together, P-Zole ISR Capsule helps in preventing acid reflux, thereby providing relief from acidity.

You are advised to take P-Zole ISR Capsule as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as headache, nausea, stomach pain, dizziness and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor before taking P-Zole ISR Capsule if you have a history of gastrointestinal bleeding, mechanical perforation/obstruction, or movement disorder. On long-term treatment, P-Zole ISR Capsule may cause osteoporosis and hypomagnesemia (low levels of magnesium). Consult your doctor if you are pregnant or breastfeeding. P-Zole ISR Capsule may cause drowsiness, so drive only if you are alert. P-Zole ISR Capsule should not be given to children as safety has not been established. Avoid consuming alcohol along with P-Zole ISR Capsule as it could lead to increased drowsiness and can elevate the production of stomach acid.

P-Zole ISR Capsule is a combination of two drugs: Pantoprazole and Itopride. Pantoprazole belongs to a group of medicines called proton pump inhibitors, whereas itopride belongs to a group of medicines called prokinetic agents. P-Zole ISR Capsule is used to treat gastro-oesophageal reflux disease (reflux of gastric contents into the oesophagus), and peptic ulcers. Pantoprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Itopride works by accelerating gastric emptying, and improves gastric sensitivity and tension. It also has anti-emetic action. Together, P-Zole ISR Capsule helps in preventing acid reflux, thereby providing relief from acidity.

• Headache
• Nausea
• Stomach pain
• Dizziness
• Diarrhoea

Do not take P-Zole ISR Capsule if you are allergic to any of its contents. Inform your doctor before taking P-Zole ISR Capsule if you have a history of gastrointestinal bleeding, mechanical perforation/obstruction, or movement disorder. P-Zole ISR Capsule may cause osteoporosis and hypomagnesemia (low magnesium) on long-term treatment. Consult your doctor if you are pregnant or breastfeeding. P-Zole ISR Capsule may cause dizziness, so drive only if you are alert. P-Zole ISR Capsule should not be given to children as safety has not been established. Avoid consuming alcohol along with P-Zole ISR Capsule as it could lead to increased drowsiness and can elevate the production of stomach acid. Keep your doctor informed about your medications and health condition to rule out any side-effects.

Drug-Drug Interactions: Inform the doctor if you are taking pain killers (aspirin, naproxen), an antidepressant (duloxetine), hypothyroidism (levothyroxine), statins (atorvastatin), blood thinner (clopidogrel), and vitamin (vitamin b12).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform the doctor if you have gastrointestinal bleeding, mechanical obstruction or perforation, Clostridium difficile-associated diarrhoea (CDAD), liver disease, bone fractures, or hypomagnesemia (low levels of magnesium).

• ASPIRIN
• NAPROXEN
• DULOXETINE
• LEVOTHYROXINE SODIUM
• ATORVASTATIN
• CLOPIDOGREL
• CYANOCOBALAMIN

• Eat smaller meals more often.

• Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

• Maintain a healthy weight by regular exercising.

• Avoid lying down after eating.

• Avoid tight-fitting clothes.

• Maintain a healthy weight by regular exercising.

• Practise relaxation techniques and avoid stress by doing yoga or meditation.

• Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda. 

• Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.

Acidity: The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like GERD, acidity, and peptic ulcers.

Gastroesophageal reflux disease (GERD): Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, sour or bitter taste in the mouth, and difficulty swallowing.

Peptic ulcers: They are sores that develop on the lining of the stomach and intestine due to erosion of the stomach's protective lining. Symptoms include nausea, changes in appetite, bloody or dark stools, unexplained weight loss, vomiting, and indigestion.