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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
PTU Tablet is an anti-thyroid medicine that regulates the synthesis and release of thyroid hormones by mellowing down the activity of the thyroid gland. This medicine is mainly used in the treatment of hyperthyroidism, graves disease, enlarged thyroid (toxic goitre), and thyrotoxicosis. You may experience side effects like nausea, indigestion, headache, body pain or a mild rash.
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Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About PTU Tablet

PTU Tablet belongs to the group of anti-thyroid drugs used in the treatment of overactive thyroid (hyperthyroidism), Grave’s disease, thyrotoxicosis, and enlarged thyroid (toxic goitre). PTU Tablet may also be used to lower very high levels of thyroid hormone prior to surgery or radioactive iodine treatment.

PTU Tablet contains 'Propylthiouracil' that regulates the synthesis and release of thyroid hormones by mellowing down the activity of the thyroid gland.

Take PTU Tablet as prescribed. In some cases, PTU Tablet may cause side effects such as nausea, indigestion, headache, body pain or a mild rash. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist. 

It is advisable to inform the doctor if you are allergic to any of the components of PTU Tablet . Keep your doctor informed if you suffer from any autoimmune disorders, blood disorders or liver disease. Consult your doctor if you are pregnant, planning to get pregnant, or if you are breastfeeding. PTU Tablet may cause dizziness, so drive only if you are alert.

Uses of PTU Tablet

Treatment of Hyperthyroidism, Graves Disease, Enlarged thyroid (toxic goitre), and Thyrotoxicosis

Directions for Use

Take PTU Tablet exactly as directed by the physician. Swallow it as a whole with a full glass of water. Do not crush, chew or break it.

Medicinal Benefits

PTU Tablet is an anti-thyroid drug used to treat hyperthyroidism and diseases that produce an overactive thyroid. It contains propylthiouracil. PTU Tablet works by inhibiting the formation of new thyroid hormones, thereby regulating the amount of thyroid hormone in the body and slowing down the thyroid gland that was otherwise in overdrive. Hence, PTU Tablet helps in treating and controlling the symptoms of excess thyroid hormone in the body, including anxiety, palpitation, a racing heartbeat, swelling in the neck (goitre), and weight loss. PTU Tablet may also be used to lower very high levels of thyroid hormone prior to surgery or radioactive iodine treatment.

How PTU Tablet Works

PTU Tablet contains 'Propylthiouracil' that regulates the synthesis and release of thyroid hormones by mellowing down the activity of the thyroid gland.

Storage

Store in a cool and dry place away from sunlight

Side Effects of PTU Tablet

  • Nausea
  • Stomach upset
  • Vomiting
  • Muscle pain
  • Rash
  • Hair loss

What if I have taken an overdose of PTU Tablet

Never take more than the prescribed dose. Bloody, black, or tarry stools, a high fever, itchy skin, pale skin, and swelling are signs of an overdose of PTU Tablet . If you experience any of these symptoms, seek emergency medical help.

Drug Warnings

It is advisable to inform the doctor if you are allergic to any of the components of PTU Tablet . Keep your doctor informed if you suffer from any autoimmune disorders, blood disorders or liver disease. Consult your doctor if you are pregnant, planning to get pregnant, or if you are breastfeeding. Inform your doctor if you have recently had any surgery or are about to undergo surgery or a dental procedure.

Drug-Drug Interactions

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PropylthiouracilClozapine
Severe
PropylthiouracilMethimazole
Severe

Drug-Drug Interactions

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PropylthiouracilClozapine
Severe
How does the drug interact with PTU Tablet 100's:
Combining PTU Tablet 100's with Clozapine can increase the risk of infection.

How to manage the interaction:
Taking PTU Tablet 100's with Clozapine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, and pain during urination. Do not stop using any medications without a doctor's advice.
PropylthiouracilMethimazole
Severe
How does the drug interact with PTU Tablet 100's:
Taking PTU Tablet 100's with Methimazole can increase the risk of side effects.

How to manage the interaction:
Co-administration of PTU Tablet 100's with Methimazole can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
PropylthiouracilKetoconazole
Severe
How does the drug interact with PTU Tablet 100's:
Coadministration of Ketoconazole and PTU Tablet 100's may increase the risk of liver problems.

How to manage the interaction:
Although taking Ketoconazole and PTU Tablet 100's together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience fever, chills, joint pain, itching, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
PropylthiouracilTeriflunomide
Severe
How does the drug interact with PTU Tablet 100's:
Coadministration of Teriflunomide with PTU Tablet 100's can increase the risk of liver problems.

How to manage the interaction:
There may be a possibility of interaction between PTU Tablet 100's and Teriflunomide, but it can be taken if prescribed by a doctor. However, if you experience any symptoms such as fever, chills, joint pain, itching, tiredness, abdominal pain, dark urine, light stools, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without first talking to your doctor.
PropylthiouracilLeflunomide
Severe
How does the drug interact with PTU Tablet 100's:
Taking PTU Tablet 100's with leflunomide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Leflunomide with PTU Tablet 100's can possibly result in an interaction, but they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain, unusual bleeding, itching, fatigue, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PropylthiouracilCarbamazepine
Severe
How does the drug interact with PTU Tablet 100's:
Taking PTU Tablet 100's with carbamazepine can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between PTU Tablet 100's and Carbamazepine, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without first talking to your doctor.
PropylthiouracilFluphenazine
Severe
How does the drug interact with PTU Tablet 100's:
Coadministration of Fluphenazine with PTU Tablet 100's can increase the risk of developing infections.

How to manage the interaction:
Co-administration of PTU Tablet 100's with Fluphenazine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, or burning urination. Do not discontinue any medications without first consulting your doctor.
PropylthiouracilMipomersen
Severe
How does the drug interact with PTU Tablet 100's:
Coadministration of Mipomersen with PTU Tablet 100's can increase the risk of liver problems.

How to manage the interaction:
Taking PTU Tablet 100's with Mipomersen together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms such as fever, chills, joint pain, tiredness, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue any medications without first consulting your doctor.
PropylthiouracilLomitapide
Severe
How does the drug interact with PTU Tablet 100's:
Coadministration of lomitapide with PTU Tablet 100's can increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between PTU Tablet 100's and Lomitapide, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as fever, chills, joint pain, itching, tiredness, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue any medications without first consulting a doctor.
PropylthiouracilDeferiprone
Severe
How does the drug interact with PTU Tablet 100's:
Coadministration of Deferiprone with Clozapine can increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between PTU Tablet 100's and Deferiprone, you can take these medicines together if prescribed by your doctor. However, contact a doctor if you experience any symptoms of infection, such as fever, chills, diarrhea, sore throat, muscle aches, or burning during urination. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Stick to a low-iodine diet to regulate the level of thyroid hormones in your body.
  • Opt for non-iodised salt, tea, egg whites, honey, maple syrup, fresh fruits, potatoes, and cauliflower to lower the iodine levels in your diet.
  • Make sure your intake of calcium, vitamin D, zinc, iron and selenium is adequate as these are very important in maintaining thyroid health. Have healthy fats, lean meats, green leafy vegetables and oily fish to regulate thyroid functioning.
  • Limit alcohol and caffeine consumption and stop smoking as these may have a negative effect on health. 
  • One of the symptoms of hyperthyroidism is anxiety and stress. Keep your mind at peace by regularly practising meditation.
  • Doing yoga can also be effective in controlling your thyroid hormones and keeping them in check.

Habit Forming

No

Therapeutic Class

THYROID AND ANTITHYROID AGENTS
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Alcohol

Caution

Not enough studies exist to establish the effects of alcohol on PTU Tablet . However, caution is advised. Please consult your doctor if you have any concerns.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or planning to become pregnant. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Safe if prescribed

PTU Tablet is safe if prescribed during breastfeeding. Please consult a doctor if you have any concerns.

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Driving

Caution

If you experience any side effects of PTU Tablet such as dizziness or drowsiness, do not drive.

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Liver

Caution

Exercise caution before using PTU Tablet in case of established liver disease. Please consult your doctor to address any concerns.

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Kidney

Safe if prescribed

PTU Tablet is probably safe on the kidney. Please consult your doctor to address any concerns.

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Children

Caution

PTU Tablet is not recommended for use in children below 6 years of age. Please consult your doctor if you have any concerns.

FAQs

PTU Tablet belongs to the group of anti-thyroid drugs used in the treatment of overactive thyroid (hyperthyroidism), Graves disease, thyrotoxicosis, and enlarged thyroid.
PTU Tablet works by inhibiting the production of new thyroid hormone and quietening an overactive thyroid gland.
No, PTU Tablet is strictly not recommended in case of hypothyroidism as PTU Tablet is an anti-thyroid drug.
In case you have missed a dose, take the missed dose as soon as possible. However, if it is almost time for the second dose, simply resume your regimen with the following dose. Do not take a double dose in any case.
Protruding eyes can be caused by hyperthyroidism because the skin around the eyes gets inflamed due to overstimulation by an excess of thyroid hormones circulating in the body and hence it bulges, creating the effect of protruding eyes.
Not enough studies exist to explain the effects of PTU Tablet on fertility. Please consult your doctor in case of any concerns or if you are trying to conceive.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - PTU0002

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