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  1. Home
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  3. P-20 Tablet 10's

Prescription drug
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P-20 Tablet 10's, Pack of 10 TABLETS
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Extra 15% Off with Bank Offers
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
P-20 Tablet is used to treat glaucoma, oedema (fluid retention), and epilepsy. Besides this, it is also used to reduce the severity and duration of altitude/mountain sickness symptoms like upset stomach, headache, shortness of breath, dizziness, drowsiness, and fatigue. This medicine works by reducing the production of fluid inside the eye. It helps treat oedema by lowering the fluid build-up and facilitating its removal through urine.
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Composition :

ACETAZOLAMIDE-250MG

Manufacturer/Marketer :

Sunways (India) Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About P-20 Tablet

P-20 Tablet belongs to a group of medicines called carbonic anhydrase inhibitors used to treat glaucoma, oedema (fluid retention), epilepsy, and to treat and prevent altitude/mountain sickness. Glaucoma is an eye condition that causes damage to the optic nerve due to abnormally increased pressure in the eye. Epilepsy is a disorder of the nervous system due to disturbed nerve cell activity in the brain. Fluid retention is a condition in which fluids are accumulated in the body tissues.
 
P-20 Tablet contains ‘acetazolamide’, which inhibits carbonic anhydrase enzyme. This inhibitory action decreases the secretion of aqueous humour, thereby lowers intraocular pressure. P-20 Tablet inhibits the carbonic anhydrase enzyme; this helps retard abnormal, excessive discharge from central nervous system neurons, thereby helps treat certain dysfunctions of the central nervous system such as epilepsy. P-20 Tablet reduces the activity of carbonic anhydrase, thereby helps lower fluid retention.
 
You are advised to take P-20 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as nausea, vomiting, diarrhoea, headache, and increased urination. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
 
Avoid taking P-20 Tablet if you are pregnant, think you are pregnant or planning for pregnancy. Consult your doctor if you are breastfeeding. P-20 Tablet is not recommended for children as safety and effectiveness have not been established. P-20 Tablet might cause dizziness and drowsiness; so, drive only if you are alert. Keep your doctor informed about your health condition and the medicines you are taking to prevent any side effects/interactions.

Uses of P-20 Tablet

P-20 Tablet used in the treatment of Glaucoma, Fluid retention/edema, Epilepsy/seizures, Mountain sickness. The detailed uses of P-20 Tablet are as follows:

  • Glaucoma Treatment: P-20 Tablet reduces intraocular pressure by decreasing aqueous humor production, helping to manage glaucoma symptoms.
  • Epilepsy Management: P-20 Tablet is used as an adjunct in treating certain types of seizures, such as tonic-clonic and absence seizures.
  • Mountain Sickness Prevention: P-20 Tablet helps to prevent and reduce symptoms of mountain sickness.
  • Edema Treatment: P-20 Tablet reduces excess fluid in the body, often caused by congestive heart failure or medications.

Have a query?

Directions for Use

  • P-20 Tablet can be taken with or without food. However, taking it with food may help prevent stomach upset.
  • It is usually taken 2-3 times daily or as advised by your doctor.
  • Swallow P-20 Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

P-20 Tablet belongs to a group of medicines called carbonic anhydrase inhibitors used to treat glaucoma, oedema (fluid retention), epilepsy, and to treat and prevent altitude/mountain sickness. P-20 Tablet works by inhibiting the carbonic anhydrase enzyme. This inhibitory action decreases the secretion of aqueous humour, thereby lowering intraocular pressure. P-20 Tablet inhibits the carbonic anhydrase enzyme; this helps retard abnormal, excessive discharge from central nervous system neurons, thereby helps treat certain dysfunctions of the central nervous system, such as epilepsy. P-20 Tablet reduces the activity of carbonic anhydrase, thereby helping lower fluid retention. P-20 Tablet may also be used to treat muscle weakness/periodic paralysis and to lower the increased pressure in the areas surrounding the spinal cord and brain.

How P-20 Tablet Works

P-20 Tablet contains ‘acetazolamide’, which inhibits carbonic anhydrase enzyme. This inhibitory action decreases the secretion of aqueous humour, thereby lowers intraocular pressure. P-20 Tablet inhibits the carbonic anhydrase enzyme; this helps retard abnormal, excessive discharge from central nervous system neurons, thereby helps treat certain dysfunctions of the central nervous system such as epilepsy. P-20 Tablet reduces the activity of carbonic anhydrase, thereby helps lower fluid retention.

Storage

• Store in a cool and dry place away from sunlight.• Keep P-20 Tablet out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of P-20 Tablet
  • Change positions or take a break from activity to relieve symptoms.
  • Avoid postures that put a lot of pressure on just one area of the body.
  • If you have vitamin deficiency, take supplements or change your diet.
  • Exercise regularly like cycling, walking or swimming.
  • Avoid sitting with your legs crossed.
  • Clench and unclench your fists and wiggle your toes.
  • Massage the affected area.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Take a balanced diet rich in protein, vitamins, and minerals.
  • Increase calorie intake if necessary, especially for children with poor appetite.
  • Engage in regular moderate-intensity exercise.
  • Promote healthy movement patterns in children.
  • Ensure adequate sleep duration by establishing a consistent sleep schedule.
  • Practice relaxation techniques like deep breathing or meditation.
  • Limit caffeine, alcohol and tobacco intake.
  • If you experience or encounter any severe allergic reaction, stop using medication and consult the doctor right away.
  • Tell your doctor about the allergic reaction, including the medication taken and any symptoms experienced.
  • Your doctor will evaluate the severity of the reaction and determine the best course of action.
  • To ensure a full recovery, follow your doctor's advice, attend scheduled follow-up appointments, and undergo recommended tests to monitor progress and adjust treatment as needed.

What if I have taken an overdose of P-20 Tablet

Take P-20 Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take P-20 Tablet if you are allergic to any of its contents; if you have severe kidney/liver problems, chronic non-congestive angle-closure glaucoma, Addison’s disease, if you have low sodium and/or potassium levels or high chlorine levels. Inform your doctor if you have lung problems, kidney stones, electrolyte imbalance, adrenal gland problems, diabetes, or heart problems. Avoid taking P-20 Tablet if you are pregnant, think you are pregnant or planning for pregnancy. Consult your doctor if you are breastfeeding. P-20 Tablet is not recommended for children as safety and effectiveness have not been established. P-20 Tablet might cause dizziness and drowsiness; so, drive only if you are alert. P-20 Tablet might make your skin sensitive to sunlight; therefore, wear protective clothing and sunscreen whilst going out.

Drug-Drug Interactions

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AcetazolamideCisapride
Critical
AcetazolamideAmiodarone
Severe

Drug-Drug Interactions

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AcetazolamideCisapride
Critical
How does the drug interact with P-20 Tablet:
Co-administration of Cisapride with P-20 Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking P-20 Tablet with Cisapride lead to an interaction, please consult a doctor before taking it. Consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not discontinue the medications without consulting a doctor.
AcetazolamideAmiodarone
Severe
How does the drug interact with P-20 Tablet:
Coadministration of amiodarone with P-20 Tablet may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Even though Amiodarone and P-20 Tablet interact, they can be used if prescribed by a doctor. If you have heart issues or electrolyte imbalances, you may be at higher risk. If you experience sudden dizziness, lightheadedness, fainting, shortness of breath, weakness, drowsiness, confusion, muscle pain, nausea, vomiting, or rapid heartbeat, get medical attention. Do not discontinue any medications without consulting a doctor.
AcetazolamideZonisamide
Severe
How does the drug interact with P-20 Tablet:
Co-administration of P-20 Tablet with Zonisamide may increase the risk or severity of metabolic acidosis (elevated levels of acid in the blood) and kidney stones.

How to manage the interaction:
Although there is a possible interaction between P-20 Tablet and Zonisamide, you can take these medicines together if prescribed by your doctor. If you experience symptoms such as fever, sudden back pain, abdominal pain, blood in the urine, tiredness, loss of appetite, irregular heartbeat, decreased sweating, trouble thinking clearly, and rapid breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AcetazolamideDroperidol
Severe
How does the drug interact with P-20 Tablet:
Co-administration of Droperidol can enhance the effects of P-20 Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction between P-20 Tablet and Droperidol, you can take these medicines together if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away: dizziness or lightheadedness, fainting, difficulty breathing, heart palpitations, weakness, feeling sleepy or confused, muscle pain, or feeling nauseous or vomiting. Do not stop using any medications without talking to a doctor.
AcetazolamideAspirin
Severe
How does the drug interact with P-20 Tablet:
Coadministration of Aspirin with P-20 Tablet may cause side effects.

How to manage the interaction:
Although there is a possible interaction between aspirin and P-20 Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as ringing in your ears, headache, nausea, vomiting, dizziness, confusion, hallucinations, or rapid breathing, fever, and seizure, please contact a doctor. Do not stop using any medications without talking to a doctor.
AcetazolamideSalsalate
Severe
How does the drug interact with P-20 Tablet:
Co-administration of P-20 Tablet together with Salsalate can cause ringing in your ears, headache, nausea, vomiting, dizziness, confusion, hallucinations, rapid breathing, fever, seizure (convulsions).

How to manage the interaction:
There may be a possibility of interaction between P-20 Tablet and Salsalate, but it can be taken if prescribed by a doctor. If you have any of these symptoms, like ringing in your ears, headache, feeling sick, throwing up, feeling dizzy, feeling confused, breathing fast, having a fever, or having a seizure, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
AcetazolamideTopiramate
Severe
How does the drug interact with P-20 Tablet:
Co-administration of P-20 Tablet with Topiramate may increase the risk of metabolic acidosis (elevated levels of acid in the blood) and kidney stone formation.

How to manage the interaction:
Although there is a possible interaction between P-20 Tablet and Topiramate, you can take these medicines together if prescribed by a doctor. If you experience symptoms of metabolic acidosis such as tiredness, loss of appetite, irregular heartbeat, trouble thinking clearly, and rapid breathing, contact a doctor immediately. Also, if you experience signs or symptoms of kidney stones, such as sudden back pain, abdominal pain, and blood in the urine, or if you have decreased sweating or a fever, contact your doctor immediately. Do not stop using any medications without consulting a doctor.
AcetazolamidePimozide
Severe
How does the drug interact with P-20 Tablet:
Co-administration of P-20 Tablet with Pimozide may increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between P-20 Tablet and Pimozide, you can take these medicines together if prescribed by a doctor. If you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats during treatment with pimozide, contact a doctor immediately. Also, inform your doctor if you experience signs of electrolyte disturbance such as weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. Do not discontinue the medication without consulting a doctor.
AcetazolamideDronedarone
Severe
How does the drug interact with P-20 Tablet:
Co-administration of P-20 Tablet with Dronedarone may increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between P-20 Tablet and Dronedarone, you can take these medicines together if prescribed by a doctor. If you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats during treatment with Dronedarone, contact a doctor immediately. Also, inform your doctor if you experience signs of electrolyte disturbance such as weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. Do not discontinue the medication without consulting a doctor.
AcetazolamideMetformin
Severe
How does the drug interact with P-20 Tablet:
Co-administration of Metformin with P-20 Tablet may increase the risk of Lactic acidosis (excessive lactic acid production in the blood).

How to manage the interaction:
Although there is a possible interaction between Metformin with P-20 Tablet, you can take these medicines together if prescribed by a doctor. However, if you have symptoms such as weakness, muscle pain, chest pain contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

GLAUCOMA:

  • Avoid intake of baked foods such as cakes, cookies, doughnuts or fried items such as French fries and stick margarine as these foods may worsen glaucoma and damage the optic nerve.

  • Limit coffee intake as it may increase pressure in the eye. Replace coffee with green tea.

  • Avoid exercises such as any position where the head is lower than the body, like an inverted yoga pose, as it may increase pressure in the eye. Doing selective exercises is advised for glaucoma patients.

EPILEPSY:

  • Exercising regularly helps in maintaining weight and improving overall health. 

  • Rest well, and get plenty of sleep.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.

  • Have a seizure response plan to help those around you know what to do.

  • Prepare your living area; small changes may help reduce the risk of physical injury during a seizure.

  • Understand what triggers seizures and try reducing or avoiding them.

  • Please pay attention to overall health, as it can help reduce seizure activity.

  • Install an alarm or emergency device to get assistance during a seizure attack.

FLUID RETENTION:

  • Limit salt intake.

  • Consume foods rich in magnesium, such as nuts, dark chocolate, whole grains, and leafy vegetables.

  • Include foods rich in vitamin B6, such as potatoes, bananas, meat, and walnuts.

  • Potassium reduces water retention, therefore, include potassium-rich foods such as avocados, tomatoes, and bananas.

  • Avoid refined carbohydrates.

  • Walking can help reduce fluid retention.

Habit Forming

No

Therapeutic Class

ANTIGLAUCOMA AGENTS

All Substitutes & Brand Comparisons

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Alcohol

Caution

Avoid or limit alcohol consumption as it might lead to increased drowsiness.

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Pregnancy

Unsafe

P-20 Tablet belongs to pregnancy category C. Avoid using P-20 Tablet if you are pregnant, think you are pregnant or planning for pregnancy. Please consult your doctor if you have any concerns regarding this.

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide if P-20 Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

P-20 Tablet might cause dizziness and drowsiness. Drive or operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Avoid taking P-20 Tablet if you have severe liver problems. Please consult your doctor if you have any concerns regarding the usage of P-20 Tablet in patients with liver impairment.

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Kidney

Caution

Dose adjustment may be needed. Avoid taking P-20 Tablet if you have/had severe kidney problems. Please consult your doctor if you have any concerns regarding the usage of P-20 Tablet in patients with kidney impairment.

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Children

Unsafe

P-20 Tablet is not recommended for children as safety and effectiveness have not been established.

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Heart

P-20 Tablet should be taken with caution in patients with heart problems. Therefore, please inform your doctor before using P-20 Tablet .

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Geriatrics

Caution

P-20 Tablet should be given with caution in elderly patients due to an increased risk of side effects. Talk to your doctor if you have any concerns.

FAQs

P-20 Tablet used to treat glaucoma, oedema (fluid retention), epilepsy, and to treat and prevent altitude/mountain sickness.

P-20 Tablet is used as an adjunct in the treatment of epilepsy. It inhibits the carbonic anhydrase enzyme; this helps retard abnormal, excessive discharge from central nervous system neurons, thereby helps treat seizures.

P-20 Tablet promotes diuresis of abnormal fluid retention due to congestive heart failure. Fluid retention or oedema is the accumulation of fluid in the body tissues.

P-20 Tablet helps reduce the severity and duration of symptoms of altitude/mountain sickness, such as headache, stomach upset, dizziness, drowsiness, fatigue, and shortness of breath.

To treat your condition effectually, continue taking P-20 Tablet for as long as your doctor has prescribed it. Do not be reluctant to speak with your doctor if you experience any difficulty while taking P-20 Tablet .

Country of origin

India

Manufacturer/Marketer address

1002-1003, 10th Floor, Windfall, Sahar Plaza, J.B.Nagar, Andheri-Kurla Road, Andheri (East), Mumbai-400059. Maharashtra, India.
Other Info - P200001

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Nov 18, 2025 | 7:25 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.2785.pdf
  2. https://www.drugs.com/mtm/acetazolamide.html
  3. https://www.medindia.net/doctors/drug_information/acetazolamide.html
  4. https://medlineplus.gov/druginfo/meds/a682756.html
  5. https://www.hpra.ie/img/uploaded/swedocuments/dcab200a-a221-43b4-9d71-5354d3cbc36a.pdf
  6. https://www.medsafe.govt.nz/consumers/cmi/d/Diamox.pdf

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