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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Oxo-TZ Tablet is used to treat various infections caused by bacteria and protozoans. It is used to treat a wide variety of infections caused by susceptible Gram-positive organisms, Gram-negative organisms, anaerobes, and protozoa such as dysentery (inflammation of the colon) and malaria. It contains Ofloxacin and Tinidazole, which kills bacteria and parasites that cause infections and prevents the further spread of the infection. It may cause side effects such as nausea, vomiting, stomach pain, loss of appetite, headache, etc. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Ind Swift Laboratories Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Oxo-TZ Tablet

Oxo-TZ Tablet is a combination of medicine called 'antibiotics' primarily used to treat various infections caused by bacteria & protozoans. Oxo-TZ Tablet is used to treat a wide variety of infections caused by susceptible Gram-positive organisms, Gram-negative organisms, anaerobes, and protozoa. Examples of infection caused by protozoa include dysentery (inflammation of the colon) and malaria. 

Oxo-TZ Tablet is a combination of two antibiotics: Ofloxacin and Tinidazole. Ofloxacin helps in treating and preventing a wide range of bacterial infections. It is bactericidal in nature, which means it works by killing bacteria that cause infections. It inhibits bacterial cells' process, ultimately destroying the bacteria, thereby preventing the further spread of the infection. Oxo-TZ Tablet is a broad-spectrum antibiotic against most Gram-negative bacteria, many Gram-positive bacteria, and some anaerobes bacteria (that live without oxygen). On the other hand, Tinidazole kills parasites and anaerobic bacteria responsible for causing infections. It works by damaging their genetic material called DNA. 

Oxo-TZ Tablet should be taken in the dose and duration your doctor advises. It is recommended to take it with food and be taken at a fixed time to achieve maximum effect. You may sometimes experience nausea, vomiting, stomach pain, loss of appetite, headache, etc. Most of these side effects of Oxo-TZ Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Please consult your doctor immediately if you experience any allergic reaction symptoms such as rashes, itching, swelling, or shortness of breath.

Inform your doctor if you have any lung disease, muscle weakness (myasthenia gravis), sleeping disorder or difficulty sleeping (sleep apnoea), severe liver disease, or problem with alcohol or other prescription recreational drugs. Inform your doctor if you plan to get pregnant, are pregnant, or are breastfeeding. Use of Oxo-TZ Tablet is associated with an increased risk of tendinitis and tendon (tough tissue that connects muscle to bone) rupture in all ages. People taking Oxo-TZ Tablet who are over 60 years are at high risk, especially those taking anti-allergic medicines like corticosteroid drugs. Oxo-TZ Tablet is contraindicated in people with kidney/heart diseases and those who have had lung transplants, should its use is not recommended.

Uses of Oxo-TZ Tablet

Treatment of Bacterial infections, Protozoal infections.

Directions for Use

This medicine can be taken with or without food (excluding dairy products). Oxo-TZ Tablet should not be used unless prescribed by a doctor. Always take this medicine exactly as your doctor has told you. Check with your doctor if you are not sure. Tablet: Swallow the tablet with water; Do not chew or crush the medicine.Suspension: Shake the bottle well before each use. Take/administer the prescribed dose using the measuring cup/dosing syringe/dropper.

Medicinal Benefits

Oxo-TZ Tablet contains antibiotic Ofloxacin and Tinidazole, which helps treat and prevent a wide range of bacterial infections caused by Gram-negative bacteria, Gram-positive bacteria and some anaerobic bacteria (that live without oxygen). It is bactericidal and works by killing bacteria that cause infections by preventing the formation of their cell wall required for living. It also inhibits the repairing of bacterial cells. Altogether it kills the bacteria. Oxo-TZ Tablet has the advantage of good penetration in most deep tissues and body fluids. Hence, it is also suitable for the treatment of deep tissue and bone bacterial infections. 

How Oxo-TZ Tablet Works

Oxo-TZ Tablet is a combination of two antibiotics: Ofloxacin and Tinidazole. Ofloxacin helps in treating and preventing a wide range of bacterial infections. It is bactericidal in nature, which means it works by killing bacteria that cause infections. It inhibits bacterial cells' process, ultimately destroying the bacteria, thereby preventing the further spread of the infection. Oxo-TZ Tablet is a broad-spectrum antibiotic against most Gram-negative bacteria, many Gram-positive bacteria, and some anaerobes bacteria (that live without oxygen). On the other hand, Tinidazole kills parasites and anaerobic bacteria responsible for causing infections. It works by damaging their genetic material called DNA.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Oxo-TZ Tablet

  • Nausea
  • Vomiting
  • Headache
  • Headache
  • Metallic taste 
  • Stomach pain
  • Loss of appetite
  • Dryness in the mouth

What if I have taken an overdose of Oxo-TZ Tablet

Do not take more than the prescribed dose of Oxo-TZ Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Oxo-TZ Tablet if you are allergic or have had a severe reaction to Ofloxacin or other quinolone or fluoroquinolone antibiotics such as Delafloxacin, Gemifloxacin, Levofloxacin, Moxifloxacin, and Ciprofloxacin. Taking Oxo-TZ Tablet may increase the chances of developing tendinitis (swelling of a fibrous tissue that connects a bone to a muscle) or having a tendon rupture (tearing of a fibrous tissue that connects a bone to a muscle). Inform your doctor if you have or have ever had a kidney, heart, or lung transplant, kidney disease, a joint or tendon disorder such as rheumatoid arthritis (an autoimmune condition of joints causing pain, swelling, and loss of function), seizures (fits), epilepsy or if you participate in regular physical activity. Taking Oxo-TZ Tablet may worsen muscle weakness in people with myasthenia gravis (a nervous system disorder that causes muscle weakness) and cause severe difficulty breathing or death. Dairy products should be avoided along with Oxo-TZ Tablet . And also, exposure to sunlight should be avoided while taking Oxo-TZ Tablet as it may cause increased phototoxicity or photosensitivity. Patients with epilepsy and irregular heartbeat (QT prolongation) should tell their doctor before taking Oxo-TZ Tablet . 

Drug-Drug Interactions

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OfloxacinMesoridazine
Critical
OfloxacinPimozide
Critical

Drug-Drug Interactions

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OfloxacinMesoridazine
Critical
How does the drug interact with Oxo-TZ Tablet 10's:
Using Mesoridazine together with Oxo-TZ Tablet 10's can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Mesoridazine with Oxo-TZ Tablet 10's is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
OfloxacinPimozide
Critical
How does the drug interact with Oxo-TZ Tablet 10's:
Coadministration of Oxo-TZ Tablet 10's with Pimozide can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Oxo-TZ Tablet 10's with Pimozide together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinBepridil
Critical
How does the drug interact with Oxo-TZ Tablet 10's:
Using bepridil together with Oxo-TZ Tablet 10's drugs can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Oxo-TZ Tablet 10's with Bepridil can cause an interaction, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop using any medications without consulting a doctor.
OfloxacinCisapride
Critical
How does the drug interact with Oxo-TZ Tablet 10's:
Coadministration of Oxo-TZ Tablet 10's with Cisapride can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Oxo-TZ Tablet 10's with Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor. Note: Cisapride is no longer available on the market. Cisapride should only be taken if prescribed by a doctor and closely monitored.
OfloxacinZiprasidone
Critical
How does the drug interact with Oxo-TZ Tablet 10's:
Coadministration of Oxo-TZ Tablet 10's with Ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Oxo-TZ Tablet 10's with Ziprasidone together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinSaquinavir
Critical
How does the drug interact with Oxo-TZ Tablet 10's:
Coadministration of Oxo-TZ Tablet 10's with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Oxo-TZ Tablet 10's with Saquinavir together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinAmiodarone
Critical
How does the drug interact with Oxo-TZ Tablet 10's:
The combination of Amiodarone and Oxo-TZ Tablet 10's may significantly increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Although Amiodarone and Oxo-TZ Tablet 10's interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without consulting a doctor.
OfloxacinThioridazine
Critical
How does the drug interact with Oxo-TZ Tablet 10's:
Coadministration of Oxo-TZ Tablet 10's with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Oxo-TZ Tablet 10's with Thioridazine together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinHalofantrine
Critical
How does the drug interact with Oxo-TZ Tablet 10's:
Using halofantrine together with Oxo-TZ Tablet 10's can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Oxo-TZ Tablet 10's with Halofantrine can cause an interaction, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
OfloxacinDisopyramide
Critical
How does the drug interact with Oxo-TZ Tablet 10's:
Coadministration of Oxo-TZ Tablet 10's with Disopyramide can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Oxo-TZ Tablet 10's with Disopyramide together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do not drink or eat many caffeine-containing products such as coffee, tea, energy drinks, cola, or chocolate. Oxo-TZ Tablet may increase nervousness, sleeplessness and anxiety caused by caffeine.
  • Probiotics should be taken after taking the full course of Oxo-TZ Tablet to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria. 
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet. Make sure you drink plenty of water or other fluids daily while taking Oxo-TZ Tablet .
  • Avoid alcoholic consumption with Oxo-TZ Tablet as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Oxo-TZ Tablet in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Oxo-TZ Tablet Substitute

Substitutes safety advice
  • Oflox TZ Tablet 10's

    by AYUR

    15.35per tablet
  • Oflomac TZ 200 mg Tablet 10's

    10.40per tablet
  • OFLOMAC TZ 100MG TABLET

    11.43per tablet
  • OFLOMAC TZ 400MG TABLET

    11.43per tablet
  • ZANOCIN TZ TABLET 10'S

    3.42per tablet
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Alcohol

Unsafe

Alcohol is not known to cause any unpleasant side effects if taken along with Oxo-TZ Tablet . But intake of alcohol with Oxo-TZ Tablet may damage your liver. So consuming alcohol should be avoided with Oxo-TZ Tablet .

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Pregnancy

Caution

Oxo-TZ Tablet is a pregnancy Category C medicine. It is not known whether Oxo-TZ Tablet will affect pregnancy. Hence, the intake of Oxo-TZ Tablet should be avoided if you are pregnant or planning to become pregnant, as it may harm your foetus. Please consult your doctor.

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Breast Feeding

Caution

Oxo-TZ Tablet is excreted in human milk. But the amount of Oxo-TZ Tablet absorbed by the nursing infant is unknown. So, it may be unsafe to be used while breastfeeding. Please consult your doctor.

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Driving

Caution

Oxo-TZ Tablet can affect alertness and coordination. So, driving vehicles and operating machinery which requires concentration should be avoided.

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Liver

Caution

Oxo-TZ Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may have to adjust the dose if there are symptoms of nausea, vomiting, loss of appetite, dark-coloured urine, or yellow discolouration of the skin/eye.

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Kidney

Caution

Oxo-TZ Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Oxo-TZ Tablet is not recommended for use in children and adolescents below 18 years of age.

FAQs

Oxo-TZ Tablet is used to treat various infections caused by bacteria and protozoans. It is used to treat a wide variety of infections caused by susceptible Gram-positive organisms, Gram-negative organisms, anaerobes, and protozoa. Examples of infection caused by protozoa include dysentery (inflammation of the colon) and malaria.
Not recommended. A patient with a transplanted kidney might be taking an immunosuppressive drug like cyclosporin which is contraindicated with Oxo-TZ Tablet failing the efficacy of the Immnosuppresant drug. There are chances of rejection of the transplanted kidney in the patient and, hence, not recommended to take Oxo-TZ Tablet without a doctor's consultation.
Do not consume alcohol or alcohol-based products while taking Oxo-TZ Tablet and at least 3 days after your treatment commences. You may experience unpleasant side effects such as fast heartbeats, nausea, vomiting, sweating and tingling under your skin.
Yes, after taking Oxo-TZ Tablet , you may have diarrhoea. Oxo-TZ Tablet is an antibiotic that kills or prevents bacterial growth, so some good intestinal bacteria that aid digestion might also get killed. So, drink plenty of fluids and take probiotics to prevent excessive loss of fluids from the body (dehydration).
It is advised not to take Oxo-TZ Tablet should not be taken along with dairy products as it might affect the absorption and efficacy of Oxo-TZ Tablet . However, you can take it with a meal that includes these foods or drinks.
Oxo-TZ Tablet makes your skin sensitive to sunlight, known as photosensitivity. So, prolonged exposure to sunlight or ultraviolet light should be avoided. In case of emergency, you should always wear sunscreen before going out.
If you miss a dose of Oxo-TZ Tablet , take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.
Take Oxo-TZ Tablet either 2 hours before or 2 hours after taking an antacid, multivitamin, or other product that has calcium/magnesium/aluminium/iron/zinc, antiulcer agent (sucralfate) or anti-HIV drug (didanosine).
No, Oxo-TZ Tablet should be taken in the dose and duration as advised by the doctor. If you take it in more than the recommended dose, it might cause unpleasant side effects. If you think your symptoms are not improving, please consult your doctor
Oxo-TZ Tablet contains lactose so tell your doctor if you are intolerant to some sugars.
It is advised to tell your doctor if you are already taking Warfarin before taking Oxo-TZ Tablet as it can increase the time it takes for blood clotting.
Take Oxo-TZ Tablet for as long as it is prescribed by your doctor. It is important to complete the full course of treatment for effective results.
Yes, Oxo-TZ Tablet can cause dryness in the mouth as a side effect. If you experience this, it's important to stay hydrated by drinking plenty of water, taking regular sips throughout the day, and keeping some water by your bed at night.
You are recommended to take your doctor’s advice before taking Oxo-TZ Tablet if you are breastfeeding as Oxo-TZ Tablet might enter breast milk and harm the unborn child.
Yes, a metallic taste may occur as a side effect of using Oxo-TZ Tablet . This is usually temporary and can be managed by chewing sugar-free gum or mints, brushing your teeth after meals, and drinking plenty of water. If this side effect persists, consult your doctor.
The use of Oxo-TZ Tablet is harmful for patients with known allergy to ofloxacin or tinidazole. It should be avoided in patients with a history of tendinitis (inflammation of the tendons), or tendon rupture upon using ofloxacin or any other medicine which belongs to the same group (quinolone group) of antimicrobial agents and in patients with some neurological disorders, kidney, or heart diseases.
Store the Oxo-TZ Tablet in a cool and dry place at room temperature away from light. Keep it out of reach of children.
Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform if your symptoms are getting worse while using this Oxo-TZ Tablet .
No, you should not stop taking Oxo-TZ Tablet even if you feel better. Complete the full course of treatment as prescribed by your doctor. If you stop using Oxo-TZ Tablet too early, your infection may worsen.
Oxo-TZ Tablet may affect alertness and coordination. Therefore, do not drive until you know how this medication affects you.
The common side effects of Oxo-TZ Tablet are nausea, vomiting, stomach pain, loss of appetite, headache and dryness in the mouth. If any of these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

SCF- 250, Ground Floor,Motor Market, ManimajraChandigarh - 160101, India.
Other Info - OXO0014

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