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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Oct 9, 2024 | 12:40 PM IST
Orni-O Tablet is used to treat bacterial infections of the urinary tract, bacterial infections by inflammation of the peritoneum, eye and ear infections, skin and soft tissue infections, sexually transmitted infections, respiratory infections, vaginal infections, protozoan infections, intra-abdominal infections, and infections during surgical procedures. It is also indicated in the treatment of diarrhoea of mixed infections in adults. It contains Ofloxacin and Ornidazole, which stops the growth of infection causing organisms. In some cases, it may cause side effects such as nausea, vomiting, abdominal pain, headache, and dizziness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Zydus Healthcare Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Orni-O Tablet

Orni-O Tablet belongs to the group of medicines called antibiotics used to treat bacterial infections of the urinary tract, bacterial infections by inflammation of the peritoneum, eye and ear infections, skin and soft tissue infections, sexually transmitted infections, respiratory infections, vaginal infections, protozoan infections, intra-abdominal infections, and infections during surgical procedures. It is also indicated in the treatment of diarrhoea of mixed infections in adults.

Orni-O Tablet is a combination of two antibiotic drugs, namely: Ofloxacin and Ornidazole. Ofloxacin inhibits DNA gyrase, which is required for the replication, transcription, and repair of the DNA. Ornidazole inhibits protein synthesis and leads to cell death, thereby killing the bacteria. Together, Orni-O Tablet helps in treating bacterial infections.

Take Orni-O Tablet as prescribed. In some cases, Orni-O Tablet may cause side effects such as nausea, vomiting, abdominal pain, headache, and dizziness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Talk to your doctor if you experience pain in tendons, swelling, and inflammation as Orni-O Tablet is associated with an increased risk of tendon rupture and tendonitis. Consult your doctor before taking Orni-O Tablet if you are pregnant or breastfeeding. Orni-O Tablet may cause dizziness and drowsiness, so drive only if you are alert. Avoid alcohol consumption while taking Orni-O Tablet as it may cause increased dizziness. Orni-O Tablet is not recommended for use in children.

Uses of Orni-O Tablet

Treatment of Bacterial infections, Diarrhoea.

Medicinal Benefits

Orni-O Tablet belongs to the group of medicines called antibiotics used to treat urinary tract infections, bacterial infections by inflammation of the peritoneum, eye and ear infections, skin and soft tissue infections, sexually transmitted infections, respiratory infections, vaginal infections, protozoan infections, intra-abdominal infections, and infections during surgical procedures. It is also indicated in the treatment of diarrhoea of mixed infections in adults. Orni-O Tablet is a combination of two antibiotic drugs, namely: Ofloxacin and Ornidazole. Ofloxacin inhibits DNA gyrase, which is required for the replication, transcription, and repair of the DNA. Ornidazole inhibits protein synthesis and leads to cell death, thereby killing the bacteria. Together, Orni-O Tablet helps in treating bacterial infections. Orni-O Tablet is a broad-spectrum antibiotic effective against a wide range of gram-positive and gram-negative bacteria.

Directions for Use

Swallow the medicine as a whole with water; do not chew, break or crush the tablet/capsule.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Orni-O Tablet

  • Nausea
  • Vomiting
  • Abdominal pain
  • Headache
  • Dizziness

Drug Warnings

Do not take Orni-O Tablet if you are allergic to any of its contents; if you had swelling or tearing of tendons while taking quinolone antibiotics; or if you have myasthenia gravis, as it may cause increased muscle weakness. Talk to your doctor before taking Orni-O Tablet if you have epilepsy, low levels of potassium, nervous or muscle problems, head injury or brain tumour, diabetes, rheumatoid arthritis, multiple sclerosis, heart, kidney or liver problems. Consult your doctor before taking Orni-O Tablet if you are pregnant or breastfeeding. Orni-O Tablet may cause dizziness and drowsiness, so drive only if you are alert. Avoid alcohol consumption while taking Orni-O Tablet as it may cause increased dizziness.

Drug Interactions

Drug-Drug Interactions: Orni-O Tablet may interact with pain killers (aspirin, ibuprofen), antibiotics (azithromycin, sulfamethoxazole, trimethoprim, metronidazole, erythromycin), corticosteroids (dexamethasone), anti-diabetic (metformin), bronchodilator (albuterol), and diuretics (furosemide).

Drug-Food Interactions: Avoid consuming milk and dairy products.

Drug-Disease Interactions: Inform your doctor if you have colitis (inflammation in the lining of the colon), tendonitis (inflammation in tendons), CNS disorders, myasthenia gravis (neuromuscular disease), peripheral neuropathy (nerve pain), crystalluria (cloudy urine), diabetes, kidney, liver and heart problems.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • IBUPROFEN
  • AZITHROMYCIN
  • TRIMETHOPRIM+SULFAMETHOXAZOLE
  • METRONIDAZOLE
  • ERYTHROMYCIN
  • DEXAMETHASONE
  • METFORMIN
  • ALBUTEROL
  • FUROSEMIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.

  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.

  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.

  • Avoid consumption of alcohol and usage of tobacco.

Special Advise

  • Orni-O Tablet may affect coagulation test or prothrombin time (time is taken for blood clotting), liver function tests, and serum tests. Orni-O Tablet contains ofloxacin which might produce false-positive urine screening results for opiates. Inform the person doing the tests that you are taking Orni-O Tablet .

  • Orni-O Tablet is associated with an increased risk of tendon rupture and tendonitis. Consult your doctor immediately if you experience tendon pain, swelling or inflammation while taking Orni-O Tablet .

Disease/Condition Glossary

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. Harmful bacteria produce chemicals known as toxins, which can damage tissue and cause sickness. It can target any body part and multiply very quickly. Symptoms include fever, chills, and fatigue. Anyone can become infected with a bacterial infection. But, people with a weak immune system or taking immunosuppressive medicine are more prone to bacterial infection.

Diarrhoea: Diarrhoea is the condition in which there is a frequent need to empty the bowels. It is characterized by loose and watery stools. The causes of diarrhoea include food intolerance, food allergy, adverse reaction to any medicine, viral infection, bacterial infection, intestinal disease, parasitic infection, and stomach or gallbladder surgery. The symptoms of diarrhoea include nausea, abdominal pain/cramps, dehydration, bloating, frequent urge to empty the bowels, and a large volume of stools or watery stools.

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Alcohol

Unsafe

Avoid consuming alcohol while taking Orni-O Tablet as it may cause increased dizziness.

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Pregnancy

Caution

Please consult your doctor if you are pregnant; your doctor will prescribe Orni-O Tablet only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Orni-O Tablet if you are breastfeeding. Your doctor will decide if Orni-O Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Orni-O Tablet may cause dizziness and drowsiness. So, drive only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor before taking Orni-O Tablet if you have liver impairment/liver disease.

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Kidney

Caution

Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking Orni-O Tablet .

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Children

Unsafe

Orni-O Tablet is not recommended for children as safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads, Ahmedabad – 380015, Gujarat, India.
Other Info - ORN0001

Author Details

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FAQs

Orni-O Tablet is used to treat bacterial infections of the urinary tract, bacterial infections by inflammation of the peritoneum, eye and ear infections, skin and soft tissue infections, sexually transmitted infections, respiratory infections, vaginal infections, protozoan infections, intra-abdominal infections, and infections during surgical procedures. It is also indicated in the treatment of diarrhoea of mixed infections in adults.
Orni-O Tablet contains Ofloxacin and Ornidazole. Ofloxacin inhibits DNA gyrase which is required for the production of DNA replication, transcription, and repair. Ornidazole inhibits protein synthesis and leads to cell death, thereby kills the bacteria. Together, Orni-O Tablet helps in treating bacterial infections.
Orni-O Tablet may cause photosensitivity (sensitivity to sunlight) and can make you sunburn easily. Avoid prolonged exposure to sunlight or tanning beds. Always wear protective clothing and sunscreen with SPF 30 or higher before going out.
It is recommended to complete the course of Orni-O Tablet even if you feel better as it is an antibiotic, and leaving it in between may lead to even severe infection. To treat your condition effectually, continue taking Orni-O Tablet for as long as your doctor has prescribed it.
Co-administration of magnesium and aluminium-containing antacids, sucralfate, and iron-containing preparations with Orni-O Tablet may reduce the absorption. Therefore, you are advised to take Orni-O Tablet two hours before such preparations.
Do not take Orni-O Tablet on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections.
Consult your doctor before taking Orni-O Tablet if you have diabetes, as Orni-O Tablet may cause hypoglycaemia (low blood sugar levels). Regularly monitor blood sugar levels while taking Orni-O Tablet to avoid unpleasant events.
It depending on the medical problem being treated. To treat your condition effectually, continue taking Orni-O Tablet for as long as your doctor has prescribed it.
No, Orni-O Tablet is not a habit-forming drug.
It is recommended to complete the course of Orni-O Tablet even if you feel better as it is an antibiotic and leaving it in between may lead to even severe infection. To treat your condition effectually, continue taking Orni-O Tablet for as long as your doctor has prescribed it.
If you miss the dose of Orni-O Tablet . Take it as soon as you remember, but if it is almost time for the next dose, skip the forgotten dose and go back to your regular schedule. Do not take double to compensate for the forgotten dose.
Please consult the doctor if you are not feeling better even after completing the recommended dose. Your doctor may prolong the duration or prescribe other medications to treat your condition.
You may take this medicine with or without food.
It is recommended not to use Orni-O Tablet if you are allergic to any component present in it.
Orni-O Tablet may cause side effects such as nausea, vomiting, abdominal pain, headache, and dizziness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
Yes, you can take it, but it should be taken only if recommended by the doctor. If you use multiple medications, your doctor will check their interactions and advise how to take them.
Store in a cool and dry place away from sunlight. Keep Orni-O Tablet out of reach and sight of children.

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