ORIPRED-125 INJECTION belongs to the corticosteroid drug class. It is used to treat symptoms associated with allergic reactions or inflammatory conditions. ORIPRED-125 INJECTION is primarily used to treat arthritis, tennis elbow, and golfer's elbow, which cause swelling and pain in the joints and tendons. It is also useful in treating severe allergic reactions, asthma, ulcerative colitis, and Crohn's disease (inflammatory bowel disease).

ORIPRED-125 INJECTION contains methylprednisolone, a corticosteroid medicine. It works by suppressing the migration of certain chemical messengers in the body that cause inflammation and allergic conditions; thus, it effectively treats various medical conditions associated with allergies and inflammation.

ORIPRED-125 INJECTION is administered by a doctor in a hospital setting. Do not self-administer. It shows side effects like depression, suicidal thoughts, anxiety, sleeping disorders, difficulty in thinking or being confused, memory loss, hallucinations (seeing or hearing things that do not exist), and feeling high (mania) or mood swings. Most of these side effects do not require medical attention and gradually resolve over time. However, if any of these side effects are persistent, consult your doctor.

Inform your doctor before receiving ORIPRED-125 INJECTION if you are allergic to corticosteroids or methylprednisolone, if you just had a vaccination or have a vaccination planned, or if you have a viral infection such as measles or chickenpox, shingles, or any other medical condition. Stay away from people who have chickenpox or shingles. Consult your doctor immediately if you come into contact with chickenpox or shingles patients. If you are pregnant or breastfeeding and suspect pregnancy or planning pregnancy, inform your doctor before receiving this medicine. ORIPRED-125 INJECTION is generally not recommended for use in children as it may delay growth and development and cause severe headaches with blurred vision or temporary visual problems in children. Your paediatrician may weigh the benefits and risks before prescribing this medicine to your child.

ORIPRED-125 INJECTION plays a vital role in treating a wide range of allergic reactions and inflammation in the body by blocking certain chemical messengers known as 'histamine,' which is naturally involved in allergic reactions. ORIPRED-125 INJECTION is accepted to treat various medical conditions such as allergies, joint inflammation (arthritis, golfer's elbow), breathing problems (e.g., asthma), and intestinal problems (e.g., ulcerative colitis, inflammatory bowel disease). Take this medicine for the duration prescribed by your doctor for its maximum benefits.

• Feeling depressed

• Suicidal thoughts

• Feeling anxious

• Sleeping disorders

• Being confused or having difficulty in thinking

• Memory loss

• Hallucinations (feeling, seeing or hearing things which do not exist)

• Feeling high (mania) or mood swings

• Having strange and frightening thoughts

• Changing how you act behavioural changes

• Loneliness and isolation (having feelings of being alone)

Inform your doctor if you are allergic to steroids, methylprednisolone, or any components present in the ORIPRED-125 INJECTION. Inform your doctor if you are pregnant or breastfeeding before receiving ORIPRED-125 INJECTION. Your doctor will weigh the benefits and potential risks before prescribing ORIPRED-125 INJECTION for you. Let your doctor know if you have bipolar disorder or depression, tuberculosis, diabetes, epilepsy, glaucoma, osteoporosis, myasthenia gravis (muscle weakness), stomach ulcers, high blood pressure or heart failure, liver or kidney problems or any viral infections or if you are about to undergo an organ transplantation procedure. ORIPRED-125 INJECTION is generally not recommended for use in children because it can cause growth and development delays as well as severe headaches with blurred vision or temporary visual problems. Individuals with poor immune systems should not take any live vaccinations while taking this medicine. It is safe to take killed vaccinations or toxoids (inactivated toxins), as their effects may be limited.

Drug-Drug Interactions: ORIPRED-125 INJECTION may interact with HIV medications (e.g. ritonavir, cobicistat), antiepilepsy drugs (e.g. carbamazepine, phenobarbital, phenytoin), antibiotics (e.g. rifampicin, rifabutin), medicines used to terminate the pregnancy (e.g. mifepristone), drugs used to treat growth problems (e.g. somatropin), antidiabetic medications (e.g. insulin), diuretics (e.g. furosemide), blood thinners (e.g. warfarin), NSAIDs (e.g. aspirin), medicines used to treat asthma (e.g. theophylline), antifungals (amphotericin, ketoconazole), drugs used to treat glaucoma (e.g. acetazolamide), medications used to treat stomach ulcers (e.g. carbenoxolone), drugs used for rheumatoid arthritis, psoriasis and certain types of cancer (e.g. methotrexate), anticancer medications (e.g. etoposide), medicines used to stop the body rejecting bone marrow or organ transplants (e.g. ciclosporin), drugs used to treat breast cancers (e.g. aminoglutethimide).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: If you ever had severe depression or manic-depressive illness (bipolar disorder), infections (bacterial/fungal/protozoal/viral), TB (tuberculosis), diabetes, epilepsy, glaucoma, osteoporosis (thinning of the bones), muscle problems, stomach ulcers, high blood pressure or heart failure, liver or kidney problems, prematurity/underweight in infancy, hypothyroidism (an under-active thyroid), or scleroderma (autoimmune disorder) or have or had a recent vaccination inform your doctor before taking ORIPRED-125 INJECTION.

• RITONAVIR
• COBICISTAT
• CARBAMAZEPINE
• PHENOBARBITAL
• RIFABUTIN
• MIFEPRISTONE
• SOMATROPIN
• INSULIN HUMAN
• FUROSEMIDE
• WARFARIN
• ASPIRIN
• THEOPHYLLINE
• AMPHOTERICIN B
• KETOCONAZOLE
• CARBENOXOLONE
• METHOTREXATE
• CICLOSPORIN
• AMINOGLUTETHIMIDE
• PHENYTOIN
• RIFAMPICIN
• ACETAZOLAMIDE
• ETOPOSIDE

• Consume antioxidant-rich food. Blueberries, tomatoes, cherries, squash, and bell peppers are high in antioxidants.
• Consuming probiotic-rich foods aids in the development of the immune system's resistance to allergies.
• Consume foods that are rich in quercetin (a flavonoid), such as apples, cherries, spinach, broccoli, and blueberries.
• Include seasonal fruits, vegetables, whole grains, healthy fats, and fish in your daily diet.
• Limit your intake of foods that may cause allergies, such as dairy products, soy, eggs, and nuts.
• Limit the consumption of foods high in sugar that may aggravate inflammation.
• Reducing stress and having a regular sleep schedule might be beneficial.
• Avoid processed meats, refined carbohydrates, sugar, trans fats, and alcohol, as they may aggravate inflammation.

Allergy: Allergy is an immune system response to foreign elements typically not harmful to your body. These foreign elements are known as 'allergens'. Allergic condition varies from person to person. Some might be allergic to certain foods and seasonal allergies like hay fever. While others might be allergic to pollen or pet dander. One of the symptoms of allergy is cough. Coughing occurs as a reflex action in the throat when mucus or any other foreign irritant is in it.

Inflammation: It is a response generated by damage to living tissues. This response is a defence mechanism to protect the body from injury, infection, or disease. The symptoms of inflammation include redness, pain, swelling, heat, or loss of function. Inflammation can be caused due to certain medications, acute and chronic conditions, exposure to foreign materials or irritants your body can’t eliminate easily.