ONOFF INJECTION

ONOFF INJECTION is used in the treatment of bacterial infections of the urinary tract, genital tract, chest, lungs, skin, and soft tissue. Bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly. ONOFF INJECTION does not work against infections caused by a virus.

ONOFF INJECTION contains Ofloxacin, which works by interfering with bacterial enzymes and DNA gyrase involved in repairing and replicating the DNA (genetic material) of bacteria. Thus, ONOFF INJECTION kills bacteria and clears the infection. 

ONOFF INJECTION will be administered by a healthcare professional. Do not self-administer. In some cases, you may experience redness, swelling or pain at the injection site, headache, nausea, and diarrhoea. Most of these side effects of ONOFF INJECTION do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Ofloxacin or other antibiotics or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, please inform your doctor before taking ONOFF INJECTION. Avoid taking ONOFF INJECTION and consult a doctor if you are breastfeeding as ONOFF INJECTION may be excreted in human milk and cause adverse effects in the baby. ONOFF INJECTION is not recommended for children below 18 years as the safety and effectiveness were not established. Drive only if you are alert, as ONOFF INJECTION may cause drowsiness, dizziness, or changes in vision. Avoid alcohol consumption with ONOFF INJECTION as it may cause sleepiness or dizziness.

ONOFF INJECTION contains Ofloxacin, a broad-spectrum antibiotic that acts against both gram-negative and gram-positive bacteria. ONOFF INJECTION is used to treat several bacterial infections. It interferes with the bacterial enzyme involved in repairing and replicating the DNA (genetic material) of bacteria. Thus, ONOFF INJECTION kills bacteria and clears the infection. 

• Redness, swelling or pain at the injection site

• Headache

• Nausea

• Diarrhoea 

If you are allergic to Ofloxacin or other antibiotics or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, please inform your doctor before taking ONOFF INJECTION. Avoid taking ONOFF INJECTION and consult a doctor if you are breastfeeding as ONOFF INJECTION may be excreted in human milk and cause adverse effects in the baby. ONOFF INJECTION is not recommended for children below 18 years as the safety and effectiveness were not established. Drive only if you are alert as ONOFF INJECTION may cause drowsiness, dizziness, or changes in vision. Avoid alcohol consumption with ONOFF INJECTION as it may cause sleepiness or dizziness. If you have low levels of magnesium or potassium in your blood, inform your doctor before taking ONOFF INJECTION. If you have received transplantation or are about to undergo an operation under general anaesthesia, inform your doctor before taking ONOFF INJECTION.

Drug-Drug Interaction: ONOFF INJECTION may interact with an anticancer drug (methotrexate), antiarrhythmics (hydroquinone, disopyramide, quinidine, sotalol, amiodarone, ibutilide, dofetilide, digoxin, procainamide), some antimicrobials, tricyclic antidepressants, some antipsychotics, blood thinner (warfarin), water pills (furosemide), anesthetics, medicines used to lower blood pressure, antidiabetic drug (glibenclamide), gout medicine (probenecid), stomach acid reducer (cimetidine), other antibiotics (clarithromycin, erythromycin, azithromycin), corticosteroids, antidepressants (imipramine, amitriptyline, clomipramine), anti-asthma drug(theophylline) and non-steroidal anti-inflammatory drugs (fenbufen, indomethacin, diclofenac, ibuprofen).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have tendinitis (swelling of tendons), epilepsy (fits), glucose-6-phosphate dehydrogenase deficiency, porphyria (illness affecting metabolism), low levels of magnesium or potassium in the blood, peripheral neuropathy (nerve problem), myasthenia gravis (muscle weakness), kidney, liver or heart problems and if you have or ever had mental health problems, inform your doctor before taking ONOFF INJECTION.

• METHOTREXATE
• HYDROQUINIDINE
• DISOPYRAMIDE
• QUINIDINE
• SOTALOL
• AMIODARONE
• IBUTILIDE
• DOFETILIDE
• DIGOXIN
• PROCAINAMIDE
• WARFARIN
• FUROSEMIDE
• GLIBENCLAMIDE
• PROBENECID
• CIMETIDINE
• CLARITHROMYCIN
• ERYTHROMYCIN
• AZITHROMYCIN
• IMIPRAMINE
• AMITRIPTYLINE
• CLOMIPRAMINE
• THEOPHYLLINE
• FENBUFEN
• INDOMETHACIN
• DICLOFENAC
• IBUPROFEN

• Take probiotics after completing the full course of ONOFF INJECTION to restore healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like cheese, yoghurt, kombucha, sauerkraut, and kimchi can help to restore the good bacteria in the intestine. 

• Include fibre-rich foods, as they can be easily digested by gut bacteria, which helps stimulate their growth. Whole grains such as whole grain bread and, brown rice should be included in your diet. 

• Make sure you drink plenty of water or other fluids every day while you are taking ONOFF INJECTION.

• Avoid alcohol consumption as it may increase adverse effects.

If you are about to undergo any blood or urine tests, inform your doctor that you are taking ONOFF INJECTION as it may interfere with certain tests.  

Bacterial infection: It is a condition in which harmful bacteria grow in the body and cause infection. It can target any part of the body and multiply very quickly. Bacteria come in three basic shapes: spherical, rod, or spiral-shaped. Bacteria may be gram-positive (have thick cell walls) or gram-negative (do not have cell walls). Appropriate tests are done to identify bacterial strains, and based on the results, proper medication is prescribed. Some common symptoms of bacterial infection include cough, fever, and tiredness.