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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Onitraz-Forte Capsule is an antifungal medicine used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. It contains Itraconazole, which works by killing fungi. Some people may experience side effects such as nausea, headache, diarrhoea, tiredness, cough, cold, throat pain, back pain and stomach pain. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

ITRACONAZOLE-200MG

Manufacturer/Marketer :

Klm Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Onitraz-Forte Capsule

Onitraz-Forte Capsule is an antifungal medicine used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. Fungal infection is a disease in which a fungus attacks the tissue and causes infection. Fungal infections may be contagious (spread from one person to another).

Onitraz-Forte Capsule contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, it causes the main components of fungal cells to leak out, kill fungi, and clear the fungal infection.

Take Onitraz-Forte Capsule as prescribed. Your doctor will advise you on how often you take Onitraz-Forte Capsule based on your medical condition. Some people may experience nausea, headache, diarrhoea, tiredness, cough, cold, throat pain, back pain and stomach pain. Most of these side effects of Onitraz-Forte Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Onitraz-Forte Capsule or any other medicines, please tell your doctor. Onitraz-Forte Capsule is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy or a nursing mother, it is advised to consult a doctor before using Onitraz-Forte Capsule . Do not take Onitraz-Forte Capsule if you have or have heart failure, as it may cause severe life-threatening adverse effects. If you have kidney, liver, heart or lung problems, inform your doctor before taking Onitraz-Forte Capsule . Avoid taking fentanyl (a strong opioid narcotic medicine) with Onitraz-Forte Capsule as it may cause severe breathing problems and can even lead to death. If you experience numbness or tingling in your hands or feet, stop taking Onitraz-Forte Capsule and consult your doctor immediately as they might be symptoms of nerve damage.

Uses of Onitraz-Forte Capsule

Treatment of Fungal infections

Directions for Use

Tablet: Take it with food to avoid stomach upset or as advised by the doctor. Swallow the whole tablet with a glass of water. Do not break, crush or chew it. If you are taking any stomach acid suppressor or have achlorhydria (stomach does not produce hydrochloric acid), take Onitraz-Forte Capsule with cola.

Medicinal Benefits

Onitraz-Forte Capsule is an antifungal used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Onitraz-Forte Capsule inhibits the production of ergosterol (a main component of cell membranes of fungi). Thereby weakening and damaging the fungal cell membranes, causing the main components of fungal cells to leak out. Thus, it kills fungi and clears the fungal infection.

How Onitraz-Forte Capsule Works

Onitraz-Forte Capsule contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, it causes the main components of fungal cells to leak out, kill fungi, and clear the fungal infection.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Onitraz-Forte Capsule

  • Nausea
  • Headache
  • Diarrhoea
  • Tiredness
  • Cough
  • Cold
  • Throat pain
  • Back pain
  • Stomach pain

What if I have taken an overdose of Onitraz-Forte Capsule

Do not take more than the prescribed dose of Onitraz-Forte Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

If you are known to be allergic to Onitraz-Forte Capsule or any other medicines, please tell your doctor. Onitraz-Forte Capsule is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy, or are a nursing mother, it is advised to consult a doctor before using Onitraz-Forte Capsule . Avoid taking fentanyl (a strong opioid pain killer narcotic medicine) with Onitraz-Forte Capsule , as it may cause severe breathing problems and can even lead to death. Do not take Onitraz-Forte Capsule if you had heart failure as it may cause severe life-threatening adverse effects. If you experience a yellow colour change of your eyes or skin, dark coloured urine, stomach pain, pale stools, loss of appetite, unusual tiredness, vomiting or nausea, stop taking Onitraz-Forte Capsule and consult a doctor immediately as they might be symptoms of liver failure. If you have kidney, liver, heart, or lung problems, inform your doctor before taking Onitraz-Forte Capsule .

Drug-Drug Interactions

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ItraconazoleSimvastatin
Critical
ItraconazoleTicagrelor
Critical

Drug-Drug Interactions

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ItraconazoleSimvastatin
Critical
How does the drug interact with Onitraz-Forte Capsule 10's:
Simvastatin's blood levels and effects may be greatly increased when combined with Onitraz-Forte Capsule 10's.

How to manage the interaction:
Simvastatin and Onitraz-Forte Capsule 10's may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you have side effects such unexplained pain in the muscles or tenderness, muscle weakness, fever or flu-like symptoms, or dark urine. Without consulting a doctor, never stop taking any medication.
ItraconazoleTicagrelor
Critical
How does the drug interact with Onitraz-Forte Capsule 10's:
The blood levels and effects of ticagrelor may be greatly increased when combined with Onitraz-Forte Capsule 10's.

How to manage the interaction:
Onitraz-Forte Capsule 10's and ticagrelor may interact, however if prescribed by a physician, they can be used together. While receiving therapy, you should consult a doctor if you develop any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Without consulting a doctor, never stop taking any medication.
ItraconazoleRanolazine
Critical
How does the drug interact with Onitraz-Forte Capsule 10's:
The blood levels and effects of Ranolazine may be greatly increased when it is used with Onitraz-Forte Capsule 10's.

How to manage the interaction:
Although Ranolazine and Onitraz-Forte Capsule 10's may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop any negative symptoms, including fainting, lightheadedness, dizziness, or rapid heartbeat. Without consulting a doctor, never stop taking any medication.
ItraconazoleIsavuconazole
Critical
How does the drug interact with Onitraz-Forte Capsule 10's:
The blood levels and effects of Isavuconazole may be significantly enhanced by taking Onitraz-Forte Capsule 10's along with it.

How to manage the interaction:
Co-administration of Isavuconazole and Onitraz-Forte Capsule 10's can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like nausea, vomiting, or diarrhoea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ItraconazoleColchicine
Critical
How does the drug interact with Onitraz-Forte Capsule 10's:
Coadministration of colchicine with Onitraz-Forte Capsule 10's may increase the blood levels of colchicine, increasing the risk of serious side effects.

How to manage the interaction:
Colchicine with Onitraz-Forte Capsule 10's can be taken if prescribed by a doctor, despite the possibility of an interaction. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop using any medications without first talking to your doctor.
ItraconazoleDisopyramide
Critical
How does the drug interact with Onitraz-Forte Capsule 10's:
Coadministration of Onitraz-Forte Capsule 10's with Disopyramide can reduce the metabolism and increase the levels of Disopyramide in the body. This may increase the risk or severity of side effects like irregular heart rhythms.

How to manage the interaction:
Taking Onitraz-Forte Capsule 10's with Disopyramide together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of headaches, dizziness, irritation, confusion, chest pain or tightness, swelling, fatigue, palpitations, shortness of breath, or constipation, you should contact your doctor immediately. Do not stop using any medications without talking to your doctor.
ItraconazoleSolifenacin
Critical
How does the drug interact with Onitraz-Forte Capsule 10's:
The blood levels and effects of solifenacin may be greatly increased when combined with Onitraz-Forte Capsule 10's.

How to manage the interaction:
Solifenacin and Onitraz-Forte Capsule 10's may interact, however, if recommended by a physician, they are safe to consume. Consult a doctor if you feel sleepy, or uneasy, have an irregular heartbeat, have blurry vision, have trouble urinating, have a dry mouth, a headache, have digestive problems, or have constipation. Without consulting a doctor, never stop taking any medication.
ItraconazoleEplerenone
Critical
How does the drug interact with Onitraz-Forte Capsule 10's:
The blood levels and effects of eplerenone may be greatly increased when combined with Onitraz-Forte Capsule 10's.

How to manage the interaction:
Although there is a possible interaction between Eplerenone and Onitraz-Forte Capsule 10's, it is not recommended; they can be taken if prescribed by a doctor. Consult a doctor if you have complications such as hyperkalemia (high blood potassium), which in extreme circumstances can result in kidney problems, muscle paralysis, and an irregular heartbeat. Without first consulting your doctor, never stop taking medicines.
ItraconazoleErgotamine
Critical
How does the drug interact with Onitraz-Forte Capsule 10's:
The blood levels and effects of ergotamine may be greatly increased when combined with Onitraz-Forte Capsule 10's.

How to manage the interaction:
Ergotamine and Onitraz-Forte Capsule 10's may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you experience a severe headache, shortness of breath, blurred vision, confusion, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of the fingers or toes, pale or cold skin, or chest pain or tightness. Without first consulting your doctor, never stop taking medicines.
ItraconazoleMethylergometrine
Critical
How does the drug interact with Onitraz-Forte Capsule 10's:
Co-administration of Methylergometrine and Onitraz-Forte Capsule 10's may increase the blood levels of Methylergometrine.

How to manage the interaction:
Methylergometrine and Onitraz-Forte Capsule 10's may interact, but if prescribed by a doctor, they can be used together. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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ITRACONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ITRACONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming Grapefruit, Grapefruit juice with Onitraz-Forte Capsule 10's may impair the absorption of Onitraz-Forte Capsule 10's, resulting in decreased antifungal effects. Avoid consuming Grapefruit and grapefruit juice with Onitraz-Forte Capsule 10's.

Diet & Lifestyle Advise

  • Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
  • In wet places such as changing rooms and gym showers, don’t walk on barefoot to prevent fungal infections.
  • Do not scratch the affected area of skin as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bed sheets and towels regularly.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Onitraz-Forte Capsule Substitute

Substitutes safety advice
  • Itracip 200 mg Capsule 10's

    24.75per tablet
  • Candiforce-200 Capsule 10's

    22.28per tablet
  • Canditral 200 Capsule 10's

    22.28per tablet
  • Syntran 200 Capsule 10's

    22.28per tablet
  • Itralase 200 Capsules 10's

    by AYUR

    22.28per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol with Onitraz-Forte Capsule as it may increase the risk of liver problems and other adverse effects.

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Pregnancy

Unsafe

Onitraz-Forte Capsule is category C pregnancy drug and is unsafe for pregnant women as it may cause harm to the unborn baby. Therefore, inform your doctor if you are pregnant or planning for pregnancy before taking Onitraz-Forte Capsule .

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Breast Feeding

Caution

Onitraz-Forte Capsule is excreted in human milk and may harm the baby. Therefore, Onitraz-Forte Capsule is given to breastfeeding mothers only if doctor thinks benefits are greater than risks.

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Driving

Caution

Onitraz-Forte Capsule may cause dizziness, hearing loss, double or blurred vision in some people. Therefore, drive only if you alert after taking Onitraz-Forte Capsule .

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Liver

Caution

Take Onitraz-Forte Capsule with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Onitraz-Forte Capsule with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Onitraz-Forte Capsule is not recommended for children below 12 years as the safety and effectiveness were not established.

FAQs

Onitraz-Forte Capsule is used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. It works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby killing fungi and clearing the fungal infection.
You are not recommended to take Onitraz-Forte Capsule with simvastatin as co-administration of these two medicines may cause muscle weakness, unexplained muscle pain or tenderness, dark coloured urine, fever or flu symptoms. However, please consult a doctor before using Onitraz-Forte Capsule with other medicines.
No, Onitraz-Forte Capsule is not recommended for use during pregnancy as it may cause harm to the fetus. Also, it is advised to use effective contraceptive measures while taking Onitraz-Forte Capsule and after 2 months of stopping treatment with Onitraz-Forte Capsule . However, please inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before taking Onitraz-Forte Capsule .
Onitraz-Forte Capsule may cause temporary or permanent hearing loss in some people. It is not necessary for everyone taking Onitraz-Forte Capsule to experience this adverse effect. However, if you notice any changes in hearing, stop taking Onitraz-Forte Capsule and consult a doctor immediately.
You are advised to take antacids (drugs used to reduce acid in the stomach) such as omeprazole, pantoprazole and esomeprazole at least 1 hour before or 2 hours after taking Onitraz-Forte Capsule as co-administration of these medicines at the same time may reduce the effectiveness of Onitraz-Forte Capsule because antacids decrease the absorption and blood levels of Onitraz-Forte Capsule . However, please consult a doctor before taking other medicines with Onitraz-Forte Capsule .
Yes, fungal infection is a contagious skin condition which spreads from one person to another through direct skin to skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person as it can also spread the infection.
You are not recommended to stop taking Onitraz-Forte Capsule without consulting your doctor as it may cause recurring infection. Therefore, take Onitraz-Forte Capsule for as long as your doctor has prescribed it, and if you experience any difficulty while taking Onitraz-Forte Capsule , please consult your doctor.
Inform your doctor if you are sexually active and discuss effective contraception methods. Onitraz-Forte Capsule may reduce the effectiveness of oral contraceptive pills. Thus, you are advised to use barrier methods of contraception like condoms, if you are taking Onitraz-Forte Capsule .
Inform the doctor about your detailed medical and surgical history, if you have liver, kidney or heart disease or fits and if you are pregnant, breastfeeding or planning pregnancy. Inform your doctor if you are taking any other medicines including supplements or herbal products as Onitraz-Forte Capsule may interact with other medicines. Also, let your doctor know if you are stopping any medicine.
Onitraz-Forte Capsule contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, it causes the main components of fungal cells to leak out, kill fungi, and clear the fungal infection.
Yes, you should swallow the capsule whole with a glass of water. Do not crush, chew or break it.
The side effects of Onitraz-Forte Capsule include nausea, headache, diarrhoea, stomach pain, fatigue (overtiredness), back pain, cough, and sore throat. If these side effects persist or worsen, please consult your doctor.
If you have taken overdose of Onitraz-Forte Capsule , please consult your doctor immediately.
Store Onitraz-Forte Capsule at room temperature. Protect from light and moisture. Keep out of reach and sight of children.

Country of origin

INDIA

Manufacturer/Marketer address

KLM LABORATORIES PVT LTD, 1004, Hubtown Viva, Jogeshwari (E), Mumbai-400060, Maharashtra, India.
Other Info - ONI0036

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