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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

One Rab-L Capsule is used to treat gastro-oesophageal reflux disease (GERD), acidity, heartburn, Zollinger-Ellison syndrome, Helicobacter pylori infection, irritable bowel syndrome, indigestion, and duodenal and gastric ulcers. It contains Rabeprazole and Levosulpiride, which work by blocking acid production and preventing the backflow of food and acid into the mouth. In some cases, this medicine may cause side effects such as headache, nausea, vomiting, gas, abdominal pain, dizziness, and diarrhoea. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Manufacturer/Marketer :

Hiilsen Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About One Rab-L Capsule

One Rab-L Capsule is used to treat gastro-oesophageal reflux disease (GERD), acidity, heartburn, Zollinger-Ellison syndrome, Helicobacter pylori infection, irritable bowel syndrome, indigestion, and duodenal and gastric ulcers.

One Rab-L Capsule is a combination of two drugs: Rabeprazole and Levosulpiride. Rabeprazole reduces stomach acid by blocking its production. Levosulpiride prevents acid and food from coming up by increasing the pressure of the inferior oesophageal (food pipe) sphincter.

In some cases, you may experience certain common side effects, such as headache, nausea, vomiting, gas, abdominal pain, dizziness, and diarrhoea. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

Inform your doctor if you have a history of gastrointestinal bleeding or intestinal obstruction. One Rab-L Capsule may cause osteoporosis (weak and brittle bones) and hypomagnesemia (low magnesium levels) with prolonged use. Consult a doctor if you are pregnant or breastfeeding.

Uses of One Rab-L Capsule

One Rab-L Capsule is used in the treatment of Gastro-oesophageal reflux disease, acidity, indigestion, heartburn, and peptic ulcers. The detailed uses of One Rab-L Capsule are as follows:

  • Gastroesophageal Reflux Disease (GERD): One Rab-L Capsule reduces acid reflux and heartburn by improving stomach emptying and lowering acid production.
  • Peptic & Duodenal Ulcers: One Rab-L Capsule promotes healing of ulcers by protecting the stomach lining.
  • Irritable Bowel Syndrome (IBS): One Rab-L Capsule is especially effective in cases with bloating and delayed gastric emptying.
  • Zollinger-Ellison Syndrome: One Rab-L Capsule manages excessive acid production due to gastrin-secreting tumours.
  • Functional Dyspepsia: One Rab-L Capsule relieves symptoms like early satiety, nausea, and abdominal discomfort.

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Directions for Use

  • One Rab-L Capsule should be taken 1 hour prior to food, or as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow One Rab-L Capsule as a whole with a glass of water.
  • Do not chew, crush or break it.

Medicinal Benefits

  • One Rab-L Capsule is a combination of two drugs: Rabeprazole and Levosulpiride, used to treat acidity-related conditions.
  • It helps treat gastro-oesophageal reflux disease (GERD), acidity, heartburn, Zollinger-Ellison syndrome, Helicobacter pylori infection, irritable bowel syndrome, indigestion, and duodenal and gastric ulcers.
  • Rabeprazole is a proton pump inhibitor that works by blocking the enzyme responsible for producing acid, known as the gastric proton pump.
  • Levosulpiride is a prokinetic agent that increases the pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth.
  • One Rab-L Capsule helps in preventing acid reflux, thereby providing relief from acidity and heartburn.

How One Rab-L Capsule Works

One Rab-L Capsule is a combination of two drugs: Rabeprazole (proton pump inhibitor) and Levosulpiride (prokinetic agent). Rabeprazole works by blocking an enzyme called the gastric proton pump, which is responsible for acid production. Levosulpiride works by increasing the pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, One Rab-L Capsule helps in preventing acid reflux, thereby providing relief from acidity and heartburn.

Storage

• Store in a cool and dry place away from sunlight.• Keep One Rab-L Capsule out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of One Rab-L Capsule
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

What if I have taken an overdose of One Rab-L Capsule

Take One Rab-L Capsule only as prescribed by the physician. Do not exceed the recommended dose, as it might cause serious side effects. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take One Rab-L Capsule if you are allergic to any of its components.
  • Inform your doctor if you have a history of pheochromocytoma (tumour of the adrenal gland), epilepsy, mania, gastrointestinal bleeding, intestinal obstruction, or severe kidney or liver impairment.
  • One Rab-L Capsule may cause osteoporosis (weak and brittle bones) and hypomagnesemia (low magnesium levels) with prolonged use.
  • Consult a doctor if you are pregnant or breastfeeding.
  • One Rab-L Capsule may cause dizziness and drowsiness, so drive only if you are alert.
  • One Rab-L Capsule is not recommended for children as safety and effectiveness have not been established.

Drug-Drug Interactions

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RabeprazoleRilpivirine
Critical

Drug-Drug Interactions

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RabeprazoleRilpivirine
Critical
How does the drug interact with One Rab-L Capsule:
Co-administration of One Rab-L Capsule can make Rilpivirine less effective by reducing its absorption in the body.

How to manage the interaction:
Taking One Rab-L Capsule with Rilpivirine is not recommended, but can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
How does the drug interact with One Rab-L Capsule:
When used in combination with erlotinib, One Rab-L Capsule may prevent the absorption of erlotinib into the circulation, which might make erlotinib less effective in treating cancer.

How to manage the interaction:
Taking One Rab-L Capsule with Erlotinib is not recommended as it can result in an interaction, it should be taken only if a doctor has advised it. Do not stop using any medications without consulting a doctor.
How does the drug interact with One Rab-L Capsule:
Co-administration of Methotrexate with One Rab-L Capsule can increase the blood levels and side effects of Methotrexate.

How to manage the interaction:
Although there is a possible interaction between One Rab-L Capsule and Methotrexate, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
RabeprazoleIdelalisib
Severe
How does the drug interact with One Rab-L Capsule:
When One Rab-L Capsule and Idelalisib are taken in combination, Idelalisib may increase the level or impact of One Rab-L Capsule.

How to manage the interaction:
Although taking One Rab-L Capsule and Idelalisib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with One Rab-L Capsule:
Co-administration of Atazanavir's blood levels and absorption can both be affected by One Rab-L Capsule, which decreases the atazanavir's ability to treat HIV.

How to manage the interaction:
Although taking One Rab-L Capsule and atazanavir together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with One Rab-L Capsule:
Taking One Rab-L Capsule together with Dasatinib results in decreased levels of Dasatinib and its effectiveness.

How to manage the interaction:
Although taking One Rab-L Capsule and Dasatinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with One Rab-L Capsule:
Taking Clopidogrel with One Rab-L Capsule can reduce the effectiveness of Clopidogrel.

How to manage the interaction:
Taking Clopidogrel and One Rab-L Capsule together possibly has an interaction, but you can take these medications together if a doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with One Rab-L Capsule:
When Phenytoin and One Rab-L Capsule are taken in combination, Phenytoin will reduce the concentration or impact of One Rab-L Capsule.

How to manage the interaction:
Although taking Phenytoin and One Rab-L Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with One Rab-L Capsule:
Taking One Rab-L Capsule together with Gefitinib results in decreased levels of gefitinib in your blood. This can result in a decreased effectiveness of gefitinib in treating the disease.

How to manage the interaction:
Although taking One Rab-L Capsule and Gefitinib together can possibly result in an interaction, it can be taken if your doctor has prescribed it. To lessen the effects of the interaction, it is advised that you take gefitinib 12 hours before or 12 hours after One Rab-L Capsule. Do not discontinue any medications without a doctor's advice.
How does the drug interact with One Rab-L Capsule:
Taking One Rab-L Capsule together with Acalabrutinib results in a decreased effectiveness of Acalabrutinib.

How to manage the interaction:
Although taking One Rab-L Capsule and Acalabrutinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight through regular exercise.
  • Avoid lying down after eating to prevent acid reflux.
  • Avoid tight-fitting clothes as they might increase the pressure on the abdomen, leading to acid reflux.
  • Practice relaxation techniques and reduce stress by incorporating yoga or meditation into your daily routine.
  • Avoid foods such as high-fat meals, spicy foods, chocolate, citrus fruits, pineapple, tomatoes, onions, garlic, tea, and soda.
  • Avoid sitting continuously, as it may trigger acidity. Take a 5-minute break every hour by doing brisk walking or stretching.

Habit Forming

No

Therapeutic Class

ANTACIDS, ANTIULCERANTS

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Alcohol

Unsafe

Avoid consumption of alcohol while taking One Rab-L Capsule . Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

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Pregnancy

Consult your doctor

Consult your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

One Rab-L Capsule may pass into breast milk. Consult your doctor if you are breastfeeding; your doctor will decide whether One Rab-L Capsule can be taken by breastfeeding mothers or not.

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Driving

Caution

One Rab-L Capsule may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Consult your doctor

Dose adjustment may be needed. Consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed. Consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

One Rab-L Capsule should not be given to children as the safety and effectiveness have not been established.

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Heart

One Rab-L Capsule should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using One Rab-L Capsule .

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Geriatrics

Caution

One Rab-L Capsule should be given with caution in elderly patients due to an increased risk of side effects. It is important to inform a healthcare professional before use.

FAQs

One Rab-L Capsule is used to treat gastro-oesophageal reflux disease (GERD), acidity, heartburn, Zollinger-Ellison syndrome, Helicobacter pylori infection, irritable bowel syndrome, indigestion, duodenal and gastric ulcers.

One Rab-L Capsule contains Rabeprazole and Levosulpiride. Rabeprazole works by blocking an enzyme called the gastric proton pump, which is responsible for producing acid. Levosulpiride works by increasing the pressure of the inferior oesophageal sphincter (food pipe), thereby preventing the backflow of food and acid into the mouth. Together, One Rab-L Capsule helps in providing relief from acidity.

Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting on a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.

One Rab-L Capsule contains rabeprazole, which might increase the risk of osteoporosis (weak and brittle bones). This mainly occurs in people taking higher doses of One Rab-L Capsule for longer durations. Inform your doctor if you are at risk of osteoporosis. Your doctor may prescribe calcium and vitamin D supplements.

Dry mouth could be a side-effect of One Rab-L Capsule . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevent drying of the mouth.

Country of origin

India

Manufacturer/Marketer address

3/1, Technical School Lane Subramaniyapuram Madurai – 625011
Other Info - ONE0228

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