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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Ondem-8 Tablet is used in the prevention of vomiting and nausea that usually occur after cancer chemotherapy, radiation treatment or surgery. It contains Ondanestron, which works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. It may cause side effects such as feeling of warmth, constipation, headache, diarrhoea, headache, drowsiness, feeling of tiredness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

ONDANSETRON-8MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Ondem-8 Tablet

Ondem-8 Tablet belongs to a group of medications called ' anti-emetics' primarily used in the prevention of vomiting (being sick) and nausea (feeling sick) that usually occur after cancer chemotherapy, radiation treatment or surgery. Nausea is an uneasy feeling in which a person feels an urge to vomit while vomiting is the natural response to the body to forcefully discharge the stomach contents.

Ondem-8 Tablet contains 'Ondanestron' that works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. As a result, Ondem-8 Tablet prevents the sensation of nausea and vomiting caused due to conditions like surgery, cancer chemotherapy, pregnancy or motion sickness.

Take Ondem-8 Tablet as prescribed. Your doctor will advise you on how often you take Ondem-8 Tablet based on your medical condition. A person taking Ondem-8 Tablet often experience side effects that include a feeling of warmth, constipation, headache, diarrhoea, headache, drowsiness, feeling of tiredness. Although, not every person faces the side effects of Ondem-8 Tablet , and even some of the unpleasant effects of Ondem-8 Tablet do not require medical attention.

The use of Ondem-8 Tablet is restricted in persons who are allergic to any of the ingredients present in this medicine. Tell your doctor if you are facing liver, kidney, or heart disorders. Ondem-8 Tablet should be used during pregnancy or breastfeeding after consulting a doctor. Ondem-8 Tablet contains lactose so tell your doctor if you have an intolerance to some sugars.

Uses of Ondem-8 Tablet

Treatment of Nausea, Vomiting.

Directions for Use

Tablet: It can be taken with or without a meal as advised by the doctor. Swallow the tablet as a whole with a glass of water. Do not break, crush or chew it. Oral disintegrating tablet/Mouth dissolving tablet (tablet MD): Check the label for directions before use. Do not handle the tablet with wet hands. Place the tablet in the mouth and allow it to dissolve. Do not swallow it as a whole.

Medicinal Benefits

Ondem-8 Tablet belongs to a group of medications called anti-emetics used to prevent nausea and vomiting associated with conditions like cancer chemotherapy, radiotherapy, surgery, pregnancy and motion sickness in adults and children above 4 years of age. When serotonin level increases in the blood, it stimulates the CTZ receptor (chemoreceptor trigger zone) located in the brain responsible for controlling nausea and vomiting. Ondem-8 Tablet acts by inhibiting the release of this serotonin, thereby preventing nausea and vomiting. 

How Ondem-8 Tablet Works

Ondem-8 Tablet contains 'Ondanestron' that works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. As a result, Ondem-8 Tablet prevents the sensation of nausea and vomiting caused due to conditions like surgery, cancer chemotherapy, pregnancy or motion sickness.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ondem-8 Tablet

  • Sensations of flushing
  • Constipation
  • Headache
  • Confusion
  • Dizziness
  • Fast heartbeat
  • Fever
  • Headache
  • Shortness of breath
  • Weakness

What if I have taken an overdose of Ondem-8 Tablet

Do not take more than the prescribed dose of Ondem-8 Tablet as it may cause overdose. The symptoms of overdose include sudden loss of vision for a short time, irregular heartbeat, constipation, fainting, dizziness or lightheadedness. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Tell your doctor if you are dealing with an uneven heart, liver problems, or any other problem. Tell your doctor if you are taking medicine for epilepsy, cancer medicines, and abnormal heartbeats. Ondem-8 Tablet may affect a person's ability to drive. Therefore, should avoid driving or operating any machine. People with an irregular heartbeat (arrhythmia), and phenylketonuria (too much of protein phenylalanine in the blood) should not take Ondem-8 Tablet as it may cause serious conditions. The liver patient should not take more than 8 mg of Ondem-8 Tablet daily. Ondem-8 Tablet should be used during pregnancy or breastfeeding after consultation with a doctor. Taking Ondem-8 Tablet with apomorphine can cause a sharp dip in blood pressure, even leading to death, so avoid its intake together.

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
OndansetronDoxepin
Severe

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
How does the drug interact with Ondem-8 Tablet 10's:
Taking Ondem-8 Tablet 10's with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Ondem-8 Tablet 10's with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
OndansetronDoxepin
Severe
How does the drug interact with Ondem-8 Tablet 10's:
When Ondem-8 Tablet 10's is taken with doxepin, it can increase the risk of serotonin syndrome (Serotonin syndrome is a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Although taking Ondem-8 Tablet 10's along with doxepin can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not stop using any medications without talking to a doctor.
OndansetronDuloxetine
Severe
How does the drug interact with Ondem-8 Tablet 10's:
Taking Ondem-8 Tablet 10's with duloxetine can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in body).

How to manage the interaction:
Although taking Ondem-8 Tablet 10's with duloxetine can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, blurred vision, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting a doctor.
OndansetronClomipramine
Severe
How does the drug interact with Ondem-8 Tablet 10's:
The combined use of Ondem-8 Tablet 10's with clomipramine can cause serotonin syndrome. (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Although taking clomipramine and Ondem-8 Tablet 10's together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not stop using any medications without talking to a doctor.
OndansetronFluoxetine
Severe
How does the drug interact with Ondem-8 Tablet 10's:
Co-administration of Ondem-8 Tablet 10's with Fluoxetine can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Although taking Ondem-8 Tablet 10's along with fluoxetine can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not stop using any medications without talking to a doctor.
OndansetronHydroxychloroquine
Severe
How does the drug interact with Ondem-8 Tablet 10's:
Taking Ondem-8 Tablet 10's with hydroxychloroquine increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Ondem-8 Tablet 10's along with hydroxychloroquine can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronOlanzapine
Severe
How does the drug interact with Ondem-8 Tablet 10's:
The combined use of Ondem-8 Tablet 10's and Olanzapine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Ondem-8 Tablet 10's and Olanzapine can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OndansetronVortioxetine
Severe
How does the drug interact with Ondem-8 Tablet 10's:
When Ondem-8 Tablet 10's, is taken with Vortioxetine it can cause serotonin syndrome (A condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Ondem-8 Tablet 10's along with Vortioxetine can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronTramadol
Severe
How does the drug interact with Ondem-8 Tablet 10's:
Co-administration of tramadol with Ondem-8 Tablet 10's can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Taking Ondem-8 Tablet 10's with tramadol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as confusion, hallucination, seizure, increased heart rate, blurred vision, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OndansetronCabozantinib
Severe
How does the drug interact with Ondem-8 Tablet 10's:
Taking Ondem-8 Tablet 10's with cabozantinib increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Ondem-8 Tablet 10's along with cabozantinib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A person should take a healthy diet that includes lots of fruits and vegetables, lean meats, skinless poultry, nuts, fish, whole grains, plant-based oils, and low-fat dairy products will help to keep a person in good health and avoid chances of nausea and vomiting. 

  • One should avoid taking greasy or oily foods as this food triggers nausea and vomit.

  • Eat cool foods instead of hot and spicy foods.

  • Include clear broths, non-fat yoghurt, fruit juice, sherbet, and sports drinks for fluid make up which has got lost due to vomiting. 

 

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Ondem-8 Tablet Substitute

Substitutes safety advice
  • Emeset 8 Tablet 10's

    9.09per tablet
  • Ondem-MD 8 Tablet 10's

    9.09per tablet
  • Zofer 8 Tablet 10's

    9.09per tablet
  • Zofer MD 8 Tablet 10's

    9.09per tablet
  • Periset-8 Tablet 10's

    8.37per tablet
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Alcohol

Unsafe

One should avoid consuming alcohol while taking Ondem-8 Tablet as this medicine can interact with alcohol and may worsen the side effects.

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Pregnancy

Safe if prescribed

Ondem-8 Tablet could be used during pregnancy after consulting a doctor.

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Breast Feeding

Safe if prescribed

Ondem-8 Tablet could be used during breastfeeding after consulting a doctor.

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Driving

Caution

Ondem-8 Tablet may cause lightheadedness in the body, so a person taking Ondem-8 Tablet should avoid driving or operating any heavy machinery or tasks that require mental alertness.

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Liver

Safe if prescribed

In persons dealing with liver problems, the use of Ondem-8 Tablet is allowed if prescribed by the doctor. However, in patients with severe liver problems should take a low dose of Ondem-8 Tablet as much as possible. Do not take more than 8 mg of Ondem-8 Tablet per day in case of liver disease.

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Kidney

Safe if prescribed

The use of Ondem-8 Tablet is safe in patients dealing with kidney disorders. No dose adjustment is required.

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Children

Safe if prescribed

Ondem-8 Tablet should not be given to the children below 4 years of age. The use of Ondem-8 Tablet is safe in children above 4 years of age if prescribed by the doctor.

FAQs

Ondem-8 Tablet is indicated in the treatment of nausea and vomiting.
Ondem-8 Tablet works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting.
Ondem-8 Tablet may cause changes in the vision, so one should avoid driving or operating any machine that required mental alertness.
People with an irregular heartbeat (arrhythmia), and phenylketonuria (too much of protein phenylalanine in the blood) should not take Ondem-8 Tablet as it may cause serious conditions. The liver patient should not take more than 8 mg of Ondem-8 Tablet daily. Taking Ondem-8 Tablet with apomorphine can cause a sharp dip in blood pressure, even leading to death, so avoid its intake together.
Ondem-8 Tablet is an anti-sickness medicine that takes about 1-2 hours to show its action.
Ondem-8 Tablet contains Ondansetron, an antiemetic drug.
Ondem-8 Tablet is ineffective in preventing nausea associated with motion sickness.
Before taking the Ondem-8 Tablet , let your doctor know about all your medical conditions, sensitivities, and medications you are using. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
Yes, Ondem-8 Tablet might make you feel sleepy or tired.
Ondem-8 Tablet usually works quickly, usually within 30 minutes, but it can take up to two hours for the full effect.
Common side effects of Ondem-8 Tablet may include warmth, constipation, headache, diarrhoea, drowsiness, and tiredness. However, not every person faces these side effects, and even some of the unpleasant effects of Ondem-8 Tablet do not require medical attention.
Ondem-8 Tablet was not found to be beneficial in the treatment of seasickness.
Ondem-8 Tablet works by blocking the action of a chemical in the body (serotonin) that is responsible for causing nausea and vomiting. As a result, Ondem-8 Tablet prevents the sensation of nausea and vomiting caused by conditions like surgery, cancer chemotherapy, pregnancy or motion sickness.
Yes, you can take Ondem-8 Tablet half an hour to 1 hour before meals.
If you forget to take a dose of Ondem-8 Tablet , take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for a forgotten dose.
Ondem-8 Tablet may cause changes in the vision, so one should avoid driving or operating any machine that requires mental alertness.
Suppose you took more than the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Ondem-8 Tablet may include constipation, dizziness or lightheadedness, fainting, irregular heartbeat, and sudden loss of vision for a short time. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.
No, Ondem-8 Tablet is not a steroid. Ondem-8 Tablet belongs to a class of drugs known as anti-emetics.
While specific dosing instructions will vary depending on your individual needs and medical history. Always follow your doctor's prescribed dosage and timing for taking these medications.
Take Ondem-8 Tablet exactly as prescribed by the doctor. Take it at the same time daily as it will help you to remember taking the medication.
Yes, Ondem-8 Tablet has also been prescribed during pregnancy to help with symptoms of nausea and vomiting in pregnancy.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - OND0002

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