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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 11, 2024 | 2:34 PM IST
Onandes 2mg/5ml Syrup is used in the prevention of vomiting and nausea that usually occur after cancer chemotherapy, radiation treatment or surgery. It contains Ondanestron, which works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. It may cause side effects such as feeling of warmth, constipation, headache, diarrhoea, headache, drowsiness, feeling of tiredness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Athens Labs Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Onandes 2mg/5ml Syrup

Onandes 2mg/5ml Syrup belongs to a group of medications called ' anti-emetics' primarily used in the prevention of vomiting (being sick) and nausea (feeling sick) that usually occur after cancer chemotherapy, radiation treatment or surgery. Nausea is an uneasy feeling in which a person feels an urge to vomit while vomiting is the natural response to the body to forcefully discharge the stomach contents.

Onandes 2mg/5ml Syrup contains 'Ondanestron' that works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. As a result, Onandes 2mg/5ml Syrup prevents the sensation of nausea and vomiting caused due to conditions like surgery, cancer chemotherapy, pregnancy or motion sickness.

Take Onandes 2mg/5ml Syrup as prescribed. Your doctor will advise you on how often you take Onandes 2mg/5ml Syrup based on your medical condition. A person taking Onandes 2mg/5ml Syrup often experience side effects that include a feeling of warmth, constipation, headache, diarrhoea, headache, drowsiness, feeling of tiredness. Although, not every person faces the side effects of Onandes 2mg/5ml Syrup, and even some of the unpleasant effects of Onandes 2mg/5ml Syrup do not require medical attention.

The use of Onandes 2mg/5ml Syrup is restricted in persons who are allergic to any of the ingredients present in this medicine. Tell your doctor if you are facing liver, kidney, or heart disorders. Onandes 2mg/5ml Syrup should be used during pregnancy or breastfeeding after consulting a doctor. Onandes 2mg/5ml Syrup contains lactose so tell your doctor if you have an intolerance to some sugars.

Uses of Onandes 2mg/5ml Syrup

Treatment of Nausea, Vomiting.

Medicinal Benefits

Onandes 2mg/5ml Syrup belongs to a group of medications called anti-emetics used to prevent nausea and vomiting associated with conditions like cancer chemotherapy, radiotherapy, surgery, pregnancy and motion sickness in adults and children above 4 years of age. When serotonin level increases in the blood, it stimulates the CTZ receptor (chemoreceptor trigger zone) located in the brain responsible for controlling nausea and vomiting. Onandes 2mg/5ml Syrup acts by inhibiting the release of this serotonin, thereby preventing nausea and vomiting. 

Directions for Use

Tablet: It can be taken with or without a meal as advised by the doctor. Swallow the tablet as a whole with a glass of water. Do not break, crush or chew it. Oral disintegrating tablet/Mouth dissolving tablet (tablet MD): Check the label for directions before use. Do not handle the tablet with wet hands. Place the tablet in the mouth and allow it to dissolve. Do not swallow it as a whole.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Onandes 2mg/5ml Syrup

  • Sensations of flushing
  • Constipation
  • Headache
  • Confusion
  • Dizziness
  • Fast heartbeat
  • Fever
  • Headache
  • Shortness of breath
  • Weakness

Drug Warnings

Tell your doctor if you are dealing with an uneven heart, liver problems, or any other problem. Tell your doctor if you are taking medicine for epilepsy, cancer medicines, and abnormal heartbeats. Onandes 2mg/5ml Syrup may affect a person's ability to drive. Therefore, should avoid driving or operating any machine. People with an irregular heartbeat (arrhythmia), and phenylketonuria (too much of protein phenylalanine in the blood) should not take Onandes 2mg/5ml Syrup as it may cause serious conditions. The liver patient should not take more than 8 mg of Onandes 2mg/5ml Syrup daily. Onandes 2mg/5ml Syrup should be used during pregnancy or breastfeeding after consultation with a doctor. Taking Onandes 2mg/5ml Syrup with apomorphine can cause a sharp dip in blood pressure, even leading to death, so avoid its intake together.

Drug Interactions

Drug-Drug Interaction: Onandes 2mg/5ml Syrup may cause a serious reaction when used with certain medicines like pain killers (acetaminophen, tramadol, ibuprofen), anti-anxiety (pregabalin, lorazepam), and antiparkinson medicine (apomorphine). 

Drug-Food Interaction: No interaction found.

Drug-Disease Interaction: The use of Onandes 2mg/5ml Syrup is restricted in people with hypokalemia (low potassium) and severe liver disease. 

Drug-Drug Interactions Checker List

  • ACETAMINOPHEN
  • TRAMADOL
  • IBUPROFEN
  • PREGABALIN
  • LORAZEPAM

Habit Forming

No

Diet & Lifestyle Advise

  • A person should take a healthy diet that includes lots of fruits and vegetables, lean meats, skinless poultry, nuts, fish, whole grains, plant-based oils, and low-fat dairy products will help to keep a person in good health and avoid chances of nausea and vomiting. 

  • One should avoid taking greasy or oily foods as this food triggers nausea and vomit.

  • Eat cool foods instead of hot and spicy foods.

  • Include clear broths, non-fat yoghurt, fruit juice, sherbet, and sports drinks for fluid make up which has got lost due to vomiting. 

 

Special Advise

  • Do not use Onandes 2mg/5ml Syrup with Apomorphine as it can cause a sudden fall of blood pressure leading to death or coma.

  • Onandes 2mg/5ml Syrup contains 'phenylalanine' so if you have Phenylketonuria (PKU) avoid its intake. 

Disease/Condition Glossary

Nausea/Vomiting: Nausea is an uneasy feeling in the stomach that may come and go in waves in which a person feels with a strong urge to vomit. It happens before vomiting. While vomiting is a natural response of the body in which a person wants to expel stomach contents from the mouth forcefully. It can be triggered by taste, anxiety, smell, pain, or irritation to the stomach. Usually, a person faces nausea and vomiting as the unpleasant effects of cancer therapy after chemotherapy and radiation therapy. It is essential to control vomiting and nausea in cancer patients for performing everyday activities of the day. If not controlled, it can lead to mental changes, loss of appetite, malnutrition, and dehydration.

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Alcohol

Unsafe

One should avoid consuming alcohol while taking Onandes 2mg/5ml Syrup as this medicine can interact with alcohol and may worsen the side effects.

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Pregnancy

Safe if prescribed

Onandes 2mg/5ml Syrup could be used during pregnancy after consulting a doctor.

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Breast Feeding

Safe if prescribed

Onandes 2mg/5ml Syrup could be used during breastfeeding after consulting a doctor.

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Driving

Caution

Onandes 2mg/5ml Syrup may cause lightheadedness in the body, so a person taking Onandes 2mg/5ml Syrup should avoid driving or operating any heavy machinery or tasks that require mental alertness.

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Liver

Safe if prescribed

In persons dealing with liver problems, the use of Onandes 2mg/5ml Syrup is allowed if prescribed by the doctor. However, in patients with severe liver problems should take a low dose of Onandes 2mg/5ml Syrup as much as possible. Do not take more than 8 mg of Onandes 2mg/5ml Syrup per day in case of liver disease.

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Kidney

Safe if prescribed

The use of Onandes 2mg/5ml Syrup is safe in patients dealing with kidney disorders. No dose adjustment is required.

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Children

Safe if prescribed

Onandes 2mg/5ml Syrup should not be given to the children below 4 years of age. The use of Onandes 2mg/5ml Syrup is safe in children above 4 years of age if prescribed by the doctor.

Country of origin

India
Other Info - ON85774

Author Details

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FAQs

Onandes 2mg/5ml Syrup is indicated in the treatment of nausea and vomiting.
Onandes 2mg/5ml Syrup works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting.
Onandes 2mg/5ml Syrup may cause changes in the vision, so one should avoid driving or operating any machine that required mental alertness.
People with an irregular heartbeat (arrhythmia), and phenylketonuria (too much of protein phenylalanine in the blood) should not take Onandes 2mg/5ml Syrup as it may cause serious conditions. The liver patient should not take more than 8 mg of Onandes 2mg/5ml Syrup daily. Taking Onandes 2mg/5ml Syrup with apomorphine can cause a sharp dip in blood pressure, even leading to death, so avoid its intake together.
Onandes 2mg/5ml Syrup is an anti-sickness medicine that takes about 1-2 hours to show its action.
Onandes 2mg/5ml Syrup contains Ondansetron, an antiemetic drug.
Onandes 2mg/5ml Syrup is ineffective in preventing nausea associated with motion sickness.
Before taking the Onandes 2mg/5ml Syrup, let your doctor know about all your medical conditions, sensitivities, and medications you are using. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
Yes, Onandes 2mg/5ml Syrup might make you feel sleepy or tired.
Onandes 2mg/5ml Syrup usually works quickly, usually within 30 minutes, but it can take up to two hours for the full effect.
Common side effects of Onandes 2mg/5ml Syrup may include warmth, constipation, headache, diarrhoea, drowsiness, and tiredness. However, not every person faces these side effects, and even some of the unpleasant effects of Onandes 2mg/5ml Syrup do not require medical attention.
Onandes 2mg/5ml Syrup was not found to be beneficial in the treatment of seasickness.
Onandes 2mg/5ml Syrup works by blocking the action of a chemical in the body (serotonin) that is responsible for causing nausea and vomiting. As a result, Onandes 2mg/5ml Syrup prevents the sensation of nausea and vomiting caused by conditions like surgery, cancer chemotherapy, pregnancy or motion sickness.
Yes, you can take Onandes 2mg/5ml Syrup half an hour to 1 hour before meals.
If you forget to take a dose of Onandes 2mg/5ml Syrup, take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for a forgotten dose.
Onandes 2mg/5ml Syrup may cause changes in the vision, so one should avoid driving or operating any machine that requires mental alertness.
Suppose you took more than the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Onandes 2mg/5ml Syrup may include constipation, dizziness or lightheadedness, fainting, irregular heartbeat, and sudden loss of vision for a short time. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.
No, Onandes 2mg/5ml Syrup is not a steroid. Onandes 2mg/5ml Syrup belongs to a class of drugs known as anti-emetics.
While specific dosing instructions will vary depending on your individual needs and medical history. Always follow your doctor's prescribed dosage and timing for taking these medications.
Take Onandes 2mg/5ml Syrup exactly as prescribed by the doctor. Take it at the same time daily as it will help you to remember taking the medication.
Yes, Onandes 2mg/5ml Syrup has also been prescribed during pregnancy to help with symptoms of nausea and vomiting in pregnancy.

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