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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Olkem-40 Tablet is used to treat high blood pressure (hypertension). It contains Olmesartan medoxomil, which widens the narrowed blood vessels. Thus, it allows the blood to flow more smoothly in the blood vessels. It may cause common side effects such as dizziness, headache, nausea, indigestion, diarrhea, stomach pain, and sore throat. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Olkem-40 Tablet

Olkem-40 Tablet belongs to a group of medications called 'anti-hypertensives' primarily used to treat high blood pressure (hypertension). High blood pressure is a chronic (long-term) condition in which blood pressure is elevated persistently at higher-than-normal levels. If left untreated, this condition can increase the risk of heart-related diseases like heart attack, heart failure, stroke, irregular heartbeat, and other complications.

Olkem-40 Tablet contains ‘Olmesartan medoxomil’, which is a prodrug hydrolyzed to olmesartan during absorption from the gastrointestinal tract. It is an angiotensin-II receptor blocker (ARB) that narrows the blood vessels, increasing the blood pressure; therefore, blocking angiotensin can result in the widening of the narrowed blood vessels. This effect allows the blood to flow more smoothly in the blood vessels.

Take Olkem-40 Tablet as prescribed. Your doctor will advise you on how often you take Olkem-40 Tablet based on your medical condition. The common side effects of Olkem-40 Tablet are dizziness, headache, nausea, indigestion, diarrhoea, stomach pain, and sore throat. Most of these side effects of Olkem-40 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

Do not take Olkem-40 Tablet if you are allergic to ‘olmesartan medoxomil’ or any ingredients present in it. Olkem-40 Tablet should not be used in pregnant women, patients suffering from jaundice (yellowing of the skin and eyes) or gallbladder blockage, patients having diabetes or kidney failure, and using blood pressure-lowering medicine containing aliskiren. Inform your doctor if you are taking potassium supplements or any other prescription or non-prescription drugs.

Uses of Olkem-40 Tablet

Treatment of Hypertension (high blood pressure)

Directions for Use

Take Olkem-40 Tablet as advised by the doctor. Swallow it whole with a glass of water. Do not crush, break, or chew it.

Medicinal Benefits

Olkem-40 Tablet contains ‘Olmesartan medoxomil’, which belongs to the class of ‘antihypertensives’. It is primarily used to reduce high blood pressure. It is an angiotensin-II receptor blocker (ARB) that blocks the hormone angiotensin. Angiotensin narrows the blood vessels, increasing the blood pressure; therefore, blocking angiotensin can result in the widening of the narrowed blood vessels. This effect allows the blood to flow more smoothly in the blood vessels, thus lowering blood pressure.

How Olkem-40 Tablet Works

Olkem-40 Tablet contains ‘Olmesartan medoxomil’, which is a prodrug hydrolyzed to olmesartan during absorption from the gastrointestinal tract. It is an angiotensin-II receptor blocker (ARB) that narrows the blood vessels, increasing the blood pressure; therefore, blocking angiotensin can result in the widening of the narrowed blood vessels. This effect allows the blood to flow more smoothly in the blood vessels.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Olkem-40 Tablet

  • Dizziness
  • Headache
  • Nausea
  • Indigestion
  • Diarrhea
  • stomach pain
  • Sore throat

What if I have taken an overdose of Olkem-40 Tablet

Do not take more than the prescribed dose of Olkem-40 Tablet as it may cause overdose and make you feel dizzy due to low blood pressure. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Olkem-40 Tablet if you are allergic to ‘olmesartan medoxomil’ or any other ingredients present in it. Inform your doctor if you have kidney problems, liver disease, heart problems, diabetes or kidney problems and take blood pressure-lowering medication containing aliskiren. Also, inform your doctor if you are taking any prescription or non-prescription drugs and nutritional supplements. During treatment, seek medical attention if you experience severe, persistent diarrhoea and substantial weight loss. It is not used in children below 2 years of age or pregnant women and should be used with caution in breastfeeding mothers.

Drug-Drug Interactions

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Olmesartan medoxomilAliskiren
Critical
Olmesartan medoxomilFosinopril
Severe

Drug-Drug Interactions

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Olmesartan medoxomilAliskiren
Critical
How does the drug interact with Olkem-40 Tablet 15's:
Using aliskiren together with olmesartan may increase the risk of serious side effects (kidney problems, low blood pressure, and high potassium levels in the blood).

How to manage the interaction:
Taking Olkem-40 Tablet 15's with Aliskiren is not recommended as it can cause an interaction, they can be taken if advised by a doctor. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat.It is crucial that you continue to consume enough fluids while taking these medications. Do not stop using any medications without consulting a doctor.
Olmesartan medoxomilFosinopril
Severe
How does the drug interact with Olkem-40 Tablet 15's:
Coadministration of Olkem-40 Tablet 15's with fosinopril may cause low blood pressure, kidney problems, and may increase potassium levels in the blood.

How to manage the interaction:
Although taking Olkem-40 Tablet 15's together with fosinopril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilPotassium chloride
Severe
How does the drug interact with Olkem-40 Tablet 15's:
Using Olkem-40 Tablet 15's with Potassium chloride may increase Potassium levels in the blood.

How to manage the interaction:
Although taking Olkem-40 Tablet 15's together with Potassium chloride may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilCaptopril
Severe
How does the drug interact with Olkem-40 Tablet 15's:
When Olkem-40 Tablet 15's is taken with captopril, it may cause low blood pressure, kidney problems, and may increase potassium levels in the blood.

How to manage the interaction:
Although taking Olkem-40 Tablet 15's with captopril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilLisinopril
Severe
How does the drug interact with Olkem-40 Tablet 15's:
Coadministration of Olkem-40 Tablet 15's with lisinopril may increase potassium levels in the blood.

How to manage the interaction:
Although taking Olkem-40 Tablet 15's together with lisinopril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilTriamterene
Severe
How does the drug interact with Olkem-40 Tablet 15's:
Taking Olkem-40 Tablet 15's with triamterene may increase potassium levels in the blood. (High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).

How to manage the interaction:
Although taking Olkem-40 Tablet 15's with triamterene may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilEnalapril
Severe
How does the drug interact with Olkem-40 Tablet 15's:
Using enalapril together with Olkem-40 Tablet 15's may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Co-administration of Enalapril with Olkem-40 Tablet 15's may lead to interaction, but it can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, and feelings of heaviness in the legs. Do not discontinue any medications without consulting a doctor.
Olmesartan medoxomilPerindopril
Severe
How does the drug interact with Olkem-40 Tablet 15's:
Coadministration of Olkem-40 Tablet 15's with perindopril may cause low blood pressure, kidney problems, and may increase potassium levels in the blood.

How to manage the interaction:
Although taking Olkem-40 Tablet 15's together with perindopril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilLithium
Severe
How does the drug interact with Olkem-40 Tablet 15's:
Taking lithium with Olkem-40 Tablet 15's may significantly increase the blood levels of lithium .

How to manage the interaction:
Although taking Olkem-40 Tablet 15's alongside lithium can lead to interaction, they can be taken if prescribed by a doctor. However, if you develop sleepiness, dizziness, confusion, loose stools, vomiting, muscular weakness, muscle incoordination, a shaking sensation, blurred vision, ringing in the ears, excessive thirst, and/or increased urination, consult a doctor. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilpotassium phosphate
Severe
How does the drug interact with Olkem-40 Tablet 15's:
Using potassium phosphate together with olmesartan may significantly increase potassium levels in the blood.

How to manage the interaction:
Although taking Olkem-40 Tablet 15's and potassium phosphate together can cause an interaction, it can be taken if a doctor has suggested it. However if you experience symptoms such as nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat, consult a doctor. It is crucial that you continue to consume enough fluids while taking these medications. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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OLMESARTAN MEDOXOMIL-40MGPotassium rich foods
Moderate

Drug-Food Interactions

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OLMESARTAN MEDOXOMIL-40MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking Olkem-40 Tablet 15's along with potassium-containing salt alternatives and over-the-counter potassium supplements might result in elevated potassium levels in your blood. High potassium levels might result in fatigue, irregular heartbeat, disorientation, tingling in the limbs, or feelings of heaviness in the legs. Avoid potassium-rich foods like tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes, and potassium-containing salt substitutes. However, if you experience symptoms such as fatigue, irregular heartbeat, disorientation, tingling in the limbs, or feelings of heaviness in the legs consult a doctor.

Diet & Lifestyle Advise

  • Keep your weight under control with a body mass index (BMI) of 19.5-24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
  • Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • Limit alcohol intake. One serving for women and two serving for men is advisable.
  • Quit smoking as it is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
  • Try to include heart-healthy omega-3 fatty acids containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Olkem-40 Tablet Substitute

Substitutes safety advice
  • Olmesar 40 Tablet 15's

    by AYUR

    21.30per tablet
  • Olmat 40 mg Tablet 15's

    19.32per tablet
  • Olmy 40 Tablet 10's

    27.77per tablet
  • Olmin 40 Tablet 10's

    21.15per tablet
  • Olsar 40 Tablet 10's

    24.57per tablet
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Alcohol

Caution

Alcohol should not be taken while using Olkem-40 Tablet . It may worsen the health condition.

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Pregnancy

Unsafe

Olkem-40 Tablet is a category C medicine and causes harmful effects to the fetus. So, it is not recommended to use in pregnant women.

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Breast Feeding

Caution

Olkem-40 Tablet should be used with caution in breastfeeding mothers. Consult your doctor before use.

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Driving

Caution

Olkem-40 Tablet may cause dizziness and affect your ability to drive.

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Liver

Caution

Olkem-40 Tablet should be used with caution in patients with liver diseases.

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Kidney

Caution

Olkem-40 Tablet should be used with extreme caution in patients with kidney diseases. Dose adjustments are necessary.

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Children

Caution

Olkem-40 Tablet is not recommended for use in children under 2 years of age. In children over 2, it should be used with caution and may require dose adjustments.

FAQs

Olkem-40 Tablet is used to treat Hypertension (high blood pressure), a chronic (long-term) condition in which blood pressure is elevated persistently at higher-than-normal levels.
Olkem-40 Tablet reduces elevated blood pressure. It is an angiotensin-II receptor blocker (ARB). It widens the narrowed blood vessels by blocking angiotensin (a hormone that narrows the blood vessels, increasing the blood pressure), therefore blocking angiotensin can result in widening of the narrowed blood vessels. This effect allows the blood to flow more smoothly in the blood vessels, thus lowering blood pressure.
You should not discontinue using Olkem-40 Tablet without consulting your doctor. The doctor may monitor your blood pressure for at least two weeks before reducing the dose and gradually stopping the medicine.
Please inform your doctor before surgery if you are taking Olkem-40 Tablet as it needs to be stopped because it might lower the blood pressure further if taken along with general anaesthesia.
Olkem-40 Tablet is a category C medicine which may cause harmful effects on the fetus. So, it is not recommended to use in pregnant women.
If it is less than 2 hours since the missed dose, take the medicine. However, if it is almost time for the next dose, do not double the dose. Take the next dose as usual at a fixed time.
Olkem-40 Tablet can be safely taken as long as your doctor has prescribed it to you. High blood pressure is a life-long condition, and you should not abruptly stop taking the medicine. Discontinuing Olkem-40 Tablet may lead to increased blood pressure with a high risk of heart attack and stroke in the future.
Eat a well-balanced diet and get regular exercise. Cut down on salt and unhealthy foods. Avoid smoking and alcohol consumption. Manage stress by doing meditation.
Olkem-40 Tablet contains Olmesartan medoxomil, an angiotensin II receptor antagonist which belongs to the class of antihypertensives medicines.
Olkem-40 Tablet can be taken with or without food.
No, Olkem-40 Tablet is an angiotensin receptor blocker (ARB) that helps treat high blood pressure.
The common side effects of Olkem-40 Tablet are dizziness, headache, nausea, indigestion, diarrhoea, stomach pain, and sore throat. If the side effects persist or worsen, please consult your doctor.
Olkem-40 Tablet may cause dizziness as a side effect. Drive or operate machinery only if you are alert.
It usually takes about a week for Olkem-40 Tablet to start lowering high blood pressure. It may take 2-8 weeks to notice full benefits of Olkem-40 Tablet .
No, Olkem-40 Tablet does not have a diuretic. It contains Olmesartan medoxomil, an angiotensin II receptor antagonist.
Take Olkem-40 Tablet as prescribed by the doctor. It is usually taken in the morning.
Olkem-40 Tablet should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.
Yes, it is safe to take Olkem-40 Tablet for the long term if prescribed by the doctor.
No, Olkem-40 Tablet does not cause weight gain. Maintain proper weight by eating healthy food and exercising regularly.
Olkem-40 Tablet should be used with caution in breastfeeding mothers. Please consult the doctor before starting Olkem-40 Tablet if you are breastfeeding.
Olkem-40 Tablet should be used with other blood pressure medicines only if prescribed by the doctor. Taking Olkem-40 Tablet with aliskiren or ACE inhibitors, such as enalapril, captopril, lisinopril or ramipril may cause interactions. Therefore, consult the doctor if you are taking these medicines.
Stopping Olkem-40 Tablet may lead to increased blood pressure with a risk of heart attack and stroke in the future. Therefore, do not discontinue Olkem-40 Tablet without consulting your doctor.
Seek immediate medical attention if you suspect an overdose of Olkem-40 Tablet . Symptoms of overdose are dizziness, fainting and fast heartbeat.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - OLK0006

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