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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Olcure Amh 20/5/12.5 Tablet is used for lowering high blood pressure (hypertension) by removing extra fluid (electrolytes) from the body. It works by relaxing and widening the narrowed blood vessels. It reduces the heart's workload and makes it more efficient at pumping blood throughout the body. Also, it removes extra water/fluid and certain electrolyte overload from the body. Thus, it lowers fluid overload and high blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke. In some cases, it may cause common side effects such as nausea, upset stomach, dehydration, headache, diarrhoea, electrolyte imbalance, headache, feeling exhausted, swollen ankles, dizziness, and decreased blood pressure. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Hbc Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Olcure Amh 20/5/12.5 Tablet

Olcure Amh 20/5/12.5 Tablet belongs to a group of medications called 'anti-hypertensives' primarily used for lowering high blood pressure (hypertension) by removing extra fluid (electrolytes) from the body. High blood pressure is a chronic condition in which the blood's force against the artery wall is high. As a result, it increases the risk of heart-related diseases like heart attack, heart failure, stroke, irregular heartbeat, and other complications.

Olcure Amh 20/5/12.5 Tablet is a combination of three medicines: Olmesartan medoximil, Amlodipine, and Hydrochlorothiazide. Olmesartan medoximil is a prodrug and breaks down into active form, i.e., olmesartan once absorbed in the GIT (Gastrointestinal tract). An angiotensin receptor blocker (ARB) blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. Amlodipine is a calcium channel blocker; it reduces the heart's workload and makes it more efficient at pumping blood throughout the body. Hydrochlorothiazide is a diuretic or water pill that removes extra water/fluid and certain electrolyte overload from the body. Together, Olcure Amh 20/5/12.5 Tablet lowers fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.

Depending upon your medical condition, you are advised to take Olcure Amh 20/5/12.5 Tablet for as long as your doctor has prescribed it for you. The most common side effects of Olcure Amh 20/5/12.5 Tablet are nausea, upset stomach, dehydration, headache, diarrhoea, electrolyte imbalance, headache, feeling exhausted, swollen ankles, dizziness, and decreased blood pressure in some cases. Most of these side effects of Olcure Amh 20/5/12.5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not use potassium supplements or salt substitutes unless your doctor tells you. In rare cases, Olcure Amh 20/5/12.5 Tablet can cause a condition that results in a skeletal muscle problem, leading to further kidney failure. If you notice unexplained muscle pain, dark-coloured urine, tenderness, or weakness, especially if you also have a fever or unexplained tiredness, immediately contact the doctor. Try not to stop taking this medicine of your own. Let your doctor know about this, as it may cause a rise in blood pressure and increase heart disease and stroke risk. Inform your doctor if you are suffering from kidney, liver, heart disease, or diabetes. If you are pregnant or breastfeeding, do not take Olcure Amh 20/5/12.5 Tablet as it is a category D pregnancy drug and may harm the baby. Do not use the Olcure Amh 20/5/12.5 Tablet if you cannot urinate, are dehydrated, have low blood pressure (hypotension), or have had cardiogenic shock (sudden stopping blood flow to the heart). Please tell your doctor if you are taking any other medicines or are allergic to this medicine. Reducing table salt (sodium chloride) in your food often helps lower blood pressure.

Uses of Olcure Amh 20/5/12.5 Tablet

Treatment of Hypertension (high blood pressure)

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Olcure Amh 20/5/12.5 Tablet belongs to a group of medications called 'anti-hypertensives' primarily used for lowering high blood pressure (hypertension) by removing extra fluid (electrolytes) from the body. Olcure Amh 20/5/12.5 Tablet is a combination of three medicines: Olmesartan medoximil, Amlodipine, and Hydrochlorothiazide. Olmesartan medoximil is a prodrug and breaks down into active form, i.e., olmesartan once absorbed in the GIT (Gastrointestinal tract). An angiotensin receptor blocker (ARB) blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. Amlodipine is a calcium channel blocker; it reduces the heart's workload and makes it more efficient at pumping blood throughout the body. Hydrochlorothiazide is a diuretic or water pill that removes extra water/fluid and certain electrolyte overload from the body. Together, Olcure Amh 20/5/12.5 Tablet lowers fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.

How Olcure Amh 20/5/12.5 Tablet Works

Olcure Amh 20/5/12.5 Tablet is a combination of three medicines: Olmesartan medoximil, Amlodipine, and Hydrochlorothiazide. Olmesartan medoximil is a prodrug and breaks down into active form, i.e., olmesartan once absorbed in the GIT (Gastrointestinal tract). An angiotensin receptor blocker (ARB) blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. Amlodipine is a calcium channel blocker; it reduces the heart's workload and makes it more efficient at pumping blood throughout the body. Hydrochlorothiazide is a diuretic or water pill that removes extra water/fluid and certain electrolyte overload from the body. Together, Olcure Amh 20/5/12.5 Tablet lowers fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.<

Storage

Store in a cool and dry place away from sunlight

Side Effects of Olcure Amh 20/5/12.5 Tablet

  • Nausea

  • Upset stomach

  • Dehydration

  • Headache

  • Dry mouth

  • Muscle cramps/weakness

  • Fast/slow/irregular heartbeat

  • Diarrhoea

  • Electrolyte imbalance

  • Headache

  • Feeling exhausted

  • Swollen ankles

  • Dizziness

  • Decreased blood pressure

What if I have taken an overdose of Olcure Amh 20/5/12.5 Tablet

Do not take more than the prescribed dose of Olcure Amh 20/5/12.5 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not use Olcure Amh 20/5/12.5 Tablet if you are pregnant, planning for pregnancy, or unable to urinate (anuria). If you have diabetes and taking Olcure Amh 20/5/12.5 Tablet with other blood pressure-lowering pills like 'aliskiren,' immediately stop taking both together and consult a doctor. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem). Olcure Amh 20/5/12.5 Tablet may pass into breast milk, so before starting Olcure Amh 20/5/12.5 Tablet , either you need to stop nursing or you should not take Olcure Amh 20/5/12.5 Tablet while breastfeeding. Please inform your doctor before surgery if you are taking Olcure Amh 20/5/12.5 Tablet as it needs to be stopped because it might lower the blood pressure further if taken along with local anaesthesia. Avoid potassium salt or its substitute intake while using Olcure Amh 20/5/12.5 Tablet to avoid any electrolyte imbalance. Olcure Amh 20/5/12.5 Tablet can pass into breast milk, but its effect on the baby is unknown. So, it is better to tell your doctor if you take Olcure Amh 20/5/12.5 Tablet and breastfeeding.

Drug-Drug Interactions

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Olmesartan medoxomilAliskiren
Critical
AmlodipineDantrolene
Critical

Drug-Drug Interactions

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Olmesartan medoxomilAliskiren
Critical
How does the drug interact with Olcure Amh 20/5/12.5 Tablet 15's:
Using aliskiren together with olmesartan may increase the risk of serious side effects (kidney problems, low blood pressure, and high potassium levels in the blood).

How to manage the interaction:
Taking Olcure Amh 20/5/12.5 Tablet 15's with Aliskiren is not recommended as it can cause an interaction, they can be taken if advised by a doctor. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat.It is crucial that you continue to consume enough fluids while taking these medications. Do not stop using any medications without consulting a doctor.
AmlodipineDantrolene
Critical
How does the drug interact with Olcure Amh 20/5/12.5 Tablet 15's:
Using Olcure Amh 20/5/12.5 Tablet 15's together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Olcure Amh 20/5/12.5 Tablet 15's with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
HydrochlorothiazideDofetilide
Critical
How does the drug interact with Olcure Amh 20/5/12.5 Tablet 15's:
Taking Dofetilide and Olcure Amh 20/5/12.5 Tablet 15's can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Dofetilide and Olcure Amh 20/5/12.5 Tablet 15's together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
HydrochlorothiazideCisapride
Critical
How does the drug interact with Olcure Amh 20/5/12.5 Tablet 15's:
Taking Cisapride and Olcure Amh 20/5/12.5 Tablet 15's can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Cisapride and Olcure Amh 20/5/12.5 Tablet 15's together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Olmesartan medoxomilEnalapril
Severe
How does the drug interact with Olcure Amh 20/5/12.5 Tablet 15's:
Using enalapril together with Olcure Amh 20/5/12.5 Tablet 15's may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Co-administration of Enalapril with Olcure Amh 20/5/12.5 Tablet 15's may lead to interaction, but it can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, and feelings of heaviness in the legs. Do not discontinue any medications without consulting a doctor.
Olmesartan medoxomilLisinopril
Severe
How does the drug interact with Olcure Amh 20/5/12.5 Tablet 15's:
Coadministration of Olcure Amh 20/5/12.5 Tablet 15's with lisinopril may increase potassium levels in the blood.

How to manage the interaction:
Although taking Olcure Amh 20/5/12.5 Tablet 15's together with lisinopril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilTriamterene
Severe
How does the drug interact with Olcure Amh 20/5/12.5 Tablet 15's:
Taking Olcure Amh 20/5/12.5 Tablet 15's with triamterene may increase potassium levels in the blood. (High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).

How to manage the interaction:
Although taking Olcure Amh 20/5/12.5 Tablet 15's with triamterene may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilpotassium phosphate
Severe
How does the drug interact with Olcure Amh 20/5/12.5 Tablet 15's:
Using potassium phosphate together with olmesartan may significantly increase potassium levels in the blood.

How to manage the interaction:
Although taking Olcure Amh 20/5/12.5 Tablet 15's and potassium phosphate together can cause an interaction, it can be taken if a doctor has suggested it. However if you experience symptoms such as nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat, consult a doctor. It is crucial that you continue to consume enough fluids while taking these medications. Do not discontinue any medications without consulting a doctor.
Olmesartan medoxomilTrimethoprim
Severe
How does the drug interact with Olcure Amh 20/5/12.5 Tablet 15's:
Taking Olcure Amh 20/5/12.5 Tablet 15's with trimethoprim may increase potassium levels in the blood.

How to manage the interaction:
Although taking Olcure Amh 20/5/12.5 Tablet 15's with trimethoprim may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilPotassium iodide
Severe
How does the drug interact with Olcure Amh 20/5/12.5 Tablet 15's:
Coadministration of Olcure Amh 20/5/12.5 Tablet 15's with potassium iodide may increase potassium levels in the blood. (High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).

How to manage the interaction:
Although taking Olcure Amh 20/5/12.5 Tablet 15's together with potassium iodide may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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HYDROCHLOROTHIAZIDE-12.5MG+AMLODIPINE-5MG+OLMESARTAN MEDOXOMIL-20MGPotassium rich foods
Moderate

Drug-Food Interactions

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HYDROCHLOROTHIAZIDE-12.5MG+AMLODIPINE-5MG+OLMESARTAN MEDOXOMIL-20MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking Olcure Amh 20/5/12.5 Tablet 15's with potassium-containing salt substitutes or potassium supplements can cause high levels of potassium in the blood. Avoid taking potassium-containing salt substitutes or potassium supplements while being treated with Olcure Amh 20/5/12.5 Tablet 15's.

Diet & Lifestyle Advise

  • Create a well-balanced and healthy diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.

  • Keep your weight under control with a BMI of 19.5-24.9.

  • Avoid chronic stress, as it can raise your blood pressure.

  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.

  • Be mindful of salt; consume no more than 2,300 mg each day.

  • Limit or avoid alcohol consumption.

  • Quitting smoking is the best strategy to lower the risk of heart disease.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Olcure Amh 20/5/12.5 Tablet Substitute

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Alcohol

Unsafe

You are recommended not to consume alcohol and Olcure Amh 20/5/12.5 Tablet to avoid unpleasant side effects like drowsiness, dizziness, and liver damage.

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Pregnancy

Unsafe

Olcure Amh 20/5/12.5 Tablet is not recommended during pregnancy as it contains Olmesartan, which is a category D pregnancy drug. This medicine may cause fetal damage and can affect the unborn baby (fetus).

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Breast Feeding

Unsafe

Olcure Amh 20/5/12.5 Tablet is known to pass breast milk, but its effect on the baby is unknown. So, before breastfeeding, let your doctor know about this. Either you need to stop breastfeeding for using Olcure Amh 20/5/12.5 Tablet or stop taking Olcure Amh 20/5/12.5 Tablet .

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Driving

Caution

Drive with caution; Olcure Amh 20/5/12.5 Tablet usually causes drowsiness and affects driving ability.

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Liver

Caution

Olcure Amh 20/5/12.5 Tablet to be taken with caution, especially if you have or have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Kidney

Caution

Olcure Amh 20/5/12.5 Tablet to be taken with caution, especially if you have had a history of kidney disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Children

Caution

Efficacy and safety of Olcure Amh 20/5/12.5 Tablet have not been established in children. If prescribed, it should be strictly under medical supervision and only if the benefits outweigh the harm.

FAQs

Olcure Amh 20/5/12.5 Tablet is used for lowering high blood pressure (hypertension) by removing extra fluid (electrolytes) from the body.
Olcure Amh 20/5/12.5 Tablet is a combination of three medicines: Olmesartan medoximil, Amlodipine, and Hydrochlorothiazide. Olmesartan medoximil relaxes and widens the narrowed blood vessels. Amlodipine reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Hydrochlorothiazide is a diuretic or water pill that removes extra water/fluid and certain electrolyte overload from the body. Together, Olcure Amh 20/5/12.5 Tablet lowers fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.
Olcure Amh 20/5/12.5 Tablet can be safely taken as long as your doctor prescribes it. Conditions such as high blood pressure are life-long conditions, and one should not abruptly discontinue it without discussing it with a doctor. Discontinuing Olcure Amh 20/5/12.5 Tablet may lead to increased blood pressure and a high risk of heart attack and stroke.
It's unlikely that Olcure Amh 20/5/12.5 Tablet affects fertility in men or women. However, in some cases, some water pills like hydrochlorothiazide may lead to erectile dysfunction. For the best advice, please consult your doctor.
Please inform your doctor before surgery if you are taking Olcure Amh 20/5/12.5 Tablet as it needs to be stopped because it might lower the blood pressure further if taken along with local anaesthesia.
Do not use Olcure Amh 20/5/12.5 Tablet if you are pregnant, planning for pregnancy, or unable to urinate. If you have diabetes and taking Olcure Amh 20/5/12.5 Tablet with other blood pressure-lowering pills like 'aliskiren', immediately stop taking both together and consult a doctor.
High blood pressure during pregnancy is called 'Pregnancy-induced hypertension (PIH). It is harmful to both the baby and the mother. In the mother, very high blood pressure can cause seizures (fits), headache, swelling of feet, kidney damage, and a higher risk of bleeding during pregnancy and delivery. This can also affect the baby by causing abnormal fetal heart rate, risk of stillbirth, and a small baby. So, during pregnancy, you should have regular blood pressure monitoring. Visit your Obstetrician if you have any concerns about blood pressure during pregnancy.
Yes, Olcure Amh 20/5/12.5 Tablet is known to cause ankle swelling (oedema) upon long-term use as Olcure Amh 20/5/12.5 Tablet amlodipine. Please try to keep your feet up when sitting for long hours. If the problem persists still, consult your doctor and do as advised.
Olcure Amh 20/5/12.5 Tablet can be taken with or without food or as advised by the doctor.
You are not recommended to stop Olcure Amh 20/5/12.5 Tablet , as stopping it may raise blood pressure and increase the risk of heart disease and stroke. Therefore, inform your doctor if you intend to stop taking Olcure Amh 20/5/12.5 Tablet or if you experience any difficulty while taking Olcure Amh 20/5/12.5 Tablet .
To control high blood pressure, it’s important to follow a balanced diet that includes proteins, whole grains, and fiber-rich fruits and vegetables. Limit your intake of carbohydrates, salt, and sugar. Before making any changes to your diet or eating habits, consult your doctor. Regular exercise and weight loss are also recommended. Avoid smoking and drinking.
You may observe a decrease in your blood pressure within 2 weeks of starting Olcure Amh 20/5/12.5 Tablet . But to notice the full effects of Olcure Amh 20/5/12.5 Tablet , it may take up to 8 weeks.
You are recommended to take the first dose before bedtime, as Olcure Amh 20/5/12.5 Tablet can cause dizziness. After the first dose, you can take Olcure Amh 20/5/12.5 Tablet at any time of day, but it’s essential to take it at the same time each day for consistency and to help you remember.
You may feel dizzy after taking Olcure Amh 20/5/12.5 Tablet as it is one of its side effects. Avoid driving if you feel dizzy. This condition doesn’t require any medical treatment as it will gradually reduce over time. Consult your doctor, if the condition persists longer.
Olcure Amh 20/5/12.5 Tablet does not usually cause weight gain. Change your lifestyle and maintain a balanced diet if you observe any changes in your weight. However, in rare cases, chronic diarrhoea with weight loss may occur. If the patient experiences diarrhoea while taking Olcure Amh 20/5/12.5 Tablet and the cause is unknown, consult a doctor.
Olcure Amh 20/5/12.5 Tablet includes side effects such as painful joints, fast heartbeat, skin rash or itchiness, chest tightness, shortness of breath, weak muscles, swelling of feet, hands, or ankles. Please, consult your doctor if you experience any of these side effects.
Take the Olcure Amh 20/5/12.5 Tablet whole with a glass of water; do not crush or chew it. To help you remember, try to take it at the same time every day.
Before taking Olcure Amh 20/5/12.5 Tablet , inform your doctor if you have kidney, liver or heart disease, diabetes, or asthma. Also, let your doctor know about all the medications you might be taking.
You are recommended to be cautious while driving or operating machinery after taking Olcure Amh 20/5/12.5 Tablet as it may cause drowsiness which affects the driving ability.
Inform your doctor about all the medications you are currently taking, as Olcure Amh 20/5/12.5 Tablet may interact with other drugs, potentially causing harmful reactions. It may interact with medications such as antidepressants (lithium), heart rhythm drugs (digoxin), blood thinners (aspirin), antidiabetics (metformin, insulin), erectile dysfunction treatments (sildenafil), cholesterol-lowering drugs (simvastatin), immune-suppressants (cyclosporine), other anti-hypertensives (atenolol), pain relievers (ibuprofen), and ulcer medications (carbenoxolone).

Country of origin

India

Manufacturer/Marketer address

Office No: B,412-419, Atria-The Business Hub, Kh Road, Sargasan Cross Roads, S.G.Highway, Gandhinagar-382421., Gujarat, India.
Other Info - OLC0049

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