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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Oct 9, 2024 | 12:36 PM IST
Ofloxacin Injection is an antibiotic used in treating bacterial infections. This medicine stops the growth of bacteria by inhibiting the gyrase enzyme and thereby helps reduce various bacterial infections of urinary tract, genital tract, chest, lungs, skin, and soft tissue. This medicine is not effective for treating viral infections. Common side effects include constipation, nausea, diarrhoea, headache, dizziness, light-headedness, pain, redness, and injection site reactions.
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Composition

OFLOXACIN-100MG

Manufacturer/Marketer

Keimed Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Ofloxacin Injection

Ofloxacin Injection is used in the treatment of bacterial infections of the urinary tract, genital tract, chest, lungs, skin, and soft tissue. Bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly. Ofloxacin Injection does not work against infections caused by a virus.

Ofloxacin Injection contains Ofloxacin, which works by interfering with bacterial enzymes and DNA gyrase involved in repairing and replicating the DNA (genetic material) of bacteria. Thus, Ofloxacin Injection kills bacteria and clears the infection. 

Ofloxacin Injection will be administered by a healthcare professional. Do not self-administer. In some cases, you may experience redness, swelling or pain at the injection site, headache, nausea, and diarrhoea. Most of these side effects of Ofloxacin Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Ofloxacin or other antibiotics or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, please inform your doctor before taking Ofloxacin Injection . Avoid taking Ofloxacin Injection and consult a doctor if you are breastfeeding as Ofloxacin Injection may be excreted in human milk and cause adverse effects in the baby. Ofloxacin Injection is not recommended for children below 18 years as the safety and effectiveness were not established. Drive only if you are alert, as Ofloxacin Injection may cause drowsiness, dizziness, or changes in vision. Avoid alcohol consumption with Ofloxacin Injection as it may cause sleepiness or dizziness.

Uses of Ofloxacin Injection

Treatment of Bacterial infections

Medicinal Benefits

Ofloxacin Injection contains Ofloxacin, a broad-spectrum antibiotic that acts against both gram-negative and gram-positive bacteria. Ofloxacin Injection is used to treat several bacterial infections. It interferes with the bacterial enzyme involved in repairing and replicating the DNA (genetic material) of bacteria. Thus, Ofloxacin Injection kills bacteria and clears the infection. 

Directions for Use

Ofloxacin Injection will be administered by a healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ofloxacin Injection

  • Redness, swelling or pain at the injection site

  • Headache

  • Nausea

  • Diarrhoea 

Drug Warnings

If you are allergic to Ofloxacin or other antibiotics or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, please inform your doctor before taking Ofloxacin Injection . Avoid taking Ofloxacin Injection and consult a doctor if you are breastfeeding as Ofloxacin Injection may be excreted in human milk and cause adverse effects in the baby. Ofloxacin Injection is not recommended for children below 18 years as the safety and effectiveness were not established. Drive only if you are alert as Ofloxacin Injection may cause drowsiness, dizziness, or changes in vision. Avoid alcohol consumption with Ofloxacin Injection as it may cause sleepiness or dizziness. If you have low levels of magnesium or potassium in your blood, inform your doctor before taking Ofloxacin Injection . If you have received transplantation or are about to undergo an operation under general anaesthesia, inform your doctor before taking Ofloxacin Injection .

Drug Interactions

Drug-Drug Interaction: Ofloxacin Injection may interact with an anticancer drug (methotrexate), antiarrhythmics (hydroquinone, disopyramide, quinidine, sotalol, amiodarone, ibutilide, dofetilide, digoxin, procainamide), some antimicrobials, tricyclic antidepressants, some antipsychotics, blood thinner (warfarin), water pills (furosemide), anesthetics, medicines used to lower blood pressure, antidiabetic drug (glibenclamide), gout medicine (probenecid), stomach acid reducer (cimetidine), other antibiotics (clarithromycin, erythromycin, azithromycin), corticosteroids, antidepressants (imipramine, amitriptyline, clomipramine), anti-asthma drug(theophylline) and non-steroidal anti-inflammatory drugs (fenbufen, indomethacin, diclofenac, ibuprofen).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have tendinitis (swelling of tendons), epilepsy (fits), glucose-6-phosphate dehydrogenase deficiency, porphyria (illness affecting metabolism), low levels of magnesium or potassium in the blood, peripheral neuropathy (nerve problem), myasthenia gravis (muscle weakness), kidney, liver or heart problems and if you have or ever had mental health problems, inform your doctor before taking Ofloxacin Injection .

Drug-Drug Interactions Checker List

  • METHOTREXATE
  • HYDROQUINIDINE
  • DISOPYRAMIDE
  • QUINIDINE
  • SOTALOL
  • AMIODARONE
  • IBUTILIDE
  • DOFETILIDE
  • DIGOXIN
  • PROCAINAMIDE
  • WARFARIN
  • FUROSEMIDE
  • GLIBENCLAMIDE
  • PROBENECID
  • CIMETIDINE
  • CLARITHROMYCIN
  • ERYTHROMYCIN
  • AZITHROMYCIN
  • IMIPRAMINE
  • AMITRIPTYLINE
  • CLOMIPRAMINE
  • THEOPHYLLINE
  • FENBUFEN
  • INDOMETHACIN
  • DICLOFENAC
  • IBUPROFEN

Habit Forming

No

Diet & Lifestyle Advise

  • Take probiotics after completing the full course of Ofloxacin Injection to restore healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like cheese, yoghurt, kombucha, sauerkraut, and kimchi can help to restore the good bacteria in the intestine. 

  • Include fibre-rich foods, as they can be easily digested by gut bacteria, which helps stimulate their growth. Whole grains such as whole grain bread and, brown rice should be included in your diet. 

  • Make sure you drink plenty of water or other fluids every day while you are taking Ofloxacin Injection .

  • Avoid alcohol consumption as it may increase adverse effects.

Special Advise

If you are about to undergo any blood or urine tests, inform your doctor that you are taking Ofloxacin Injection as it may interfere with certain tests.  

Disease/Condition Glossary

Bacterial infection: It is a condition in which harmful bacteria grow in the body and cause infection. It can target any part of the body and multiply very quickly. Bacteria come in three basic shapes: spherical, rod, or spiral-shaped. Bacteria may be gram-positive (have thick cell walls) or gram-negative (do not have cell walls). Appropriate tests are done to identify bacterial strains, and based on the results, proper medication is prescribed. Some common symptoms of bacterial infection include cough, fever, and tiredness. 

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Alcohol

Unsafe

Avoid alcohol consumption with Ofloxacin Injection as it may cause dizziness or sleepiness. Please consult a doctor before consuming alcohol while using Ofloxacin Injection .

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Pregnancy

Caution

Please consult a doctor if you are pregnant or planning for pregnancy. Ofloxacin Injection is given to pregnant women only if doctor thinks benefits outweigh risks.

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Breast Feeding

Unsafe

Ofloxacin Injection may be excreted in human milk. Therefore, Ofloxacin Injection is not recommended for breastfeeding mothers. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Ofloxacin Injection may cause dizziness, drowsiness or changes in vision. Therefore, drive only if you are alert after taking Ofloxacin Injection .

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Liver

Caution

Take Ofloxacin Injection with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Ofloxacin Injection with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Ofloxacin Injection is not recommended for children below 18 years of age as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

B19&20, Medak - Hyderabad Road, Sanath Nagar IE, Sanath Nagar, Hyderabad, Telangana 500018, India
Other Info - OFL0032

Author Details

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FAQs

Ofloxacin Injection is used in the treatment of bacterial infections of the urinary tract, genital tract, chest, lungs, skin, and soft tissue.
Ofloxacin Injection works by interfering with bacterial enzyme, DNA gyrase involved in repairing and replicating the DNA (genetic material) of bacteria. Thus, Ofloxacin Injection kills bacteria and clears the infection.
Ofloxacin Injection may be used to treat lung infections caused by bacteria. Ofloxacin Injection is an antibiotic that kills bacteria and prevents the spread of infection.
You are not recommended to take Ofloxacin Injection with warfarin as co-administration of these two medicines may increase the risk of bleeding more easily. However, please consult your doctor before taking Ofloxacin Injection with other medicines.
Ofloxacin Injection may cause diarrhoea as a common side effect. However, if the condition persists, worsens or if you notice blood or mucus in stools, consult a doctor immediately.
Ofloxacin Injection is not used to treat viral infections. Ofloxacin Injection is an antibiotic which is used to treat only bacterial infections.

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