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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Nov 10, 2024 | 7:19 PM IST
Odoxil Premix 250 Suspension is used to treat bacterial infections of upper respiratory tract, skin and soft tissue, and the urinary system. It contains Cefadroxil, which kills the bacteria and treats bacterial infections. It may cause common side effects such as diarrhoea, nausea, vomiting, sore tongue, abdominal pain, dyspepsia (indigestion), skin rash, and itching. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition

CEFADROXIL-250MG

Manufacturer/Marketer

Lupin Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-26

for this medicine

About Odoxil Premix 250 Suspension

Odoxil Premix 250 Suspension belongs to the class of cephalosporin antibiotics. It is used to treat upper respiratory tract bacterial infections, the skin and soft tissue, and the urinary system. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick.

Odoxil Premix 250 Suspension contains cefadroxil, which is a new semisynthetic cephalosporin with a broad antibacterial spectrum and a high chemotherapeutic potential when administered orally. It kills the bacteria by inhibiting cell wall synthesis, leading to cell death. Thereby it treats bacterial infections.

Use Odoxil Premix 250 Suspension as suggested by the doctor. Your doctor will advise the dose and duration based on the severity of your infection. Like all medicines, Odoxil Premix 250 Suspension also causes side effects, although not everybody gets them. Common side effects of Odoxil Premix 250 Suspension include diarrhoea, nausea, vomiting, sore tongue, abdominal pain, dyspepsia (indigestion), skin rash, and itching. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently. 

Before starting Odoxil Premix 250 Suspension, please inform your doctor if you have any allergy to any antibiotic or kidney or liver problems. Do not take the Odoxil Premix 250 Suspension on your own, as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections. Consult your doctor before taking the Odoxil Premix 250 Suspension if you are pregnant or breastfeeding. Avoid alcohol consumption while taking Odoxil Premix 250 Suspension as it may cause increased dizziness.

Uses of Odoxil Premix 250 Suspension

Treatment of Bacterial infections

Medicinal Benefits

Odoxil Premix 250 Suspension belongs to the class of cephalosporin antibiotics. It reduces the infection by inhibiting bacterial growth. It kills the bacteria by disrupting the formation of the cell wall. It irreversibly binds to the proteins in the bacteria that are essential for the formation of the cell membrane. Thereby it treats bacterial infections. Odoxil Premix 250 Suspension is a broad-spectrum antibiotic that is effective against both gram-positive and gram-negative bacteria.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole.Oral Suspension/syrup: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.Dry syrup: Check the label for directions before use. Mix the content in the prescribed amount of water, mix well and drink as directed by the physician.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Odoxil Premix 250 Suspension

  • Nausea
  • Vomiting
  • Diarrhoea
  • Indigestion
  • Abdominal pain
  • Severe itching
  • Rash
  • Allergic skin eruptions
  • Hives
  • A swollen, sore tongue

Drug Warnings

Before taking Odoxil Premix 250 Suspension, tell your doctor if you are allergic to cefadroxil, cephalosporin antibiotics, or penicillin. People allergic to penicillin may also experience an allergy to cefadroxil due to cross-sensitivity (sensitivity to one drug may cause sensitivity to another drug if they have a similar chemical structure). You may experience ‘Clostridium difficile associated diarrhoea (CDAD)’ after using Odoxil Premix 250 Suspension. So, tell your doctor if you are previously diagnosed with gastrointestinal disease (affecting the stomach or intestine), especially colitis (inflammation of the inner lining of the colon (large intestine)). In addition, tell your doctor if you have a history of kidney disease, as dosage adjustments are necessary.

Drug Interactions

Drug-Drug interactions: Odoxil Premix 250 Suspension may interact with vaccinations (e.g. typhoid vaccine live, cholera vaccine live, BCG)

Drug-Food interactions: Alcohol may alter the efficacy of Odoxil Premix 250 Suspension.

Drug-Disease interactions: Odoxil Premix 250 Suspension interacted with disease conditions, including colitis (inflammation of the inner wall of the intestine), seizures (sudden, uncontrolled electrical disturbance in the brain) and renal impairment.

Drug-Drug Interactions Checker List

  • TYPHOID VACCINE LIVE
  • CHOLERA VACCINE LIVE
  • BCG VACCINE

Habit Forming

No

Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Odoxil Premix 250 Suspension to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains, like whole-grain bread, and brown rice, should be included in your diet.
  • Avoid taking too much calcium-enriched foods and drinks as it might affect the working of Odoxil Premix 250 Suspension.
  • Avoid intake of alcoholic beverages with Odoxil Premix 250 Suspension as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Odoxil Premix 250 Suspension in fighting off infections.

Special Advise

  • Your doctor may take blood samples to monitor electrolyte levels in the body. This helps determine the renal (kidney) function as Odoxil Premix 250 Suspension may cause renal toxicity. 

Disease/Condition Glossary

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms, like fevers, chills, and fatigue. Bacteria are of various forms comprising commonly spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine are more prone to bacterial infection.

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Alcohol

Caution

Intake of alcohol while taking Odoxil Premix 250 Suspension may increase the risk of side effects.

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Pregnancy

Caution

Odoxil Premix 250 Suspension is a category B medicine. It should be used in pregnant women only when required and prescribed by your doctor.

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Breast Feeding

Caution

Odoxil Premix 250 Suspension may be excreted in breast milk in low amounts. So, it should be used with caution in breastfeeding mothers.

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Driving

Safe if prescribed

Odoxil Premix 250 Suspension should not affect your ability to drive or use machines.

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Liver

Caution

Odoxil Premix 250 Suspension to be taken with caution, especially if you have a history of liver diseases/conditions. Odoxil Premix 250 Suspension dose may have to be adjusted by your doctor.

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Kidney

Caution

Odoxil Premix 250 Suspension should be used in patients with kidney diseases with extreme caution as Odoxil Premix 250 Suspension may cause renal toxicity. Dose adjustments are necessary.

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Children

Caution

Odoxil Premix 250 Suspension should be given to children only if prescribed by a doctor. The dose and duration may vary depending upon the age and severity of the infection.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India.
Other Info - ODO0007

Author Details

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FAQs

Odoxil Premix 250 Suspension is used to treat bacterial infections of upper respiratory tract, skin and soft tissue, and the urinary system.
Odoxil Premix 250 Suspension reduces the infection by inhibiting bacterial growth. It disrupts the formation of the cell membrane by interfering with protein synthesis, leading to cell death.
Odoxil Premix 250 Suspension may disrupt the natural flora present in the intestine leading to ‘Clostridium difficile associated diarrhea'. Take probiotics to restore the gut bacteria after completing the course of antibiotics. Consult a doctor if you have watery or bloody stools.
People allergic to penicillin should not take Odoxil Premix 250 Suspension as they may develop cross-sensitivity (sensitivity to drugs that has similar structures). Odoxil Premix 250 Suspension contains cefadroxil which has a similar structure to that of penicillin.
Complete the course of therapy as prescribed by your doctor. Do not discontinue or abruptly stop the medication as it may lead to antibiotic resistance, a condition in which bacteria become resistant to antibiotics.
Overdose of Odoxil Premix 250 Suspension may lead to nausea, hallucinations (seeing or hearing things that are unreal), hyperreflexia (overactive reflexes), extrapyramidal symptoms (involuntary muscle movements), confusion, and a decrease in renal function. Consult a doctor immediately if you accidentally overdose on medicine.
Odoxil Premix 250 Suspension does not treat a viral infection like the flu or a common cold. So if you are feeling under the weather, it is best to consult the doctor to know if you need Odoxil Premix 250 Suspension for your condition.
Common side effects of Odoxil Premix 250 Suspension include diarrhoea, nausea, vomiting, sore tongue, abdominal pain, dyspepsia (indigestion), skin rash, and itching. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Yes, Odoxil Premix 250 Suspension is an antibiotic. It contains cefadroxil, which is a new semisynthetic cephalosporin antibiotic with a broad antibacterial spectrum.
In some cases, Odoxil Premix 250 Suspension may cause serious side effects like severe stomach pain, watery/bloody diarrhoea, flu symptoms, seizures, confusion, yellowing of skin/eyes, dark colour urine, and kidney problems. Consult the doctor if you notice any of these symptoms.
To prevent any unpleasant side effects/interactions, it is advised to consult the doctor before taking other medications with Odoxil Premix 250 Suspension.

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