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  3. O-Tab 20 Tablet 10's

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O-Tab 20 Tablet 10's, Pack of 10 TABLETS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

O-Tab 20 Tablet is used to treat gastroesophageal reflux disease (GERD), peptic ulcer (stomach or duodenal ulcer), and Zollinger-Ellison syndrome (overproduction of acid due to a pancreatic tumor). It contains Omeprazole, which helps reduce stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), acid reflux, or heartburn. It may cause common side effects such as stomach pain, gas formation (flatulence), nausea, vomiting, diarrhea, and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and any pre-existing medical conditions.

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Composition :

OMEPRAZOLE-20MG

Manufacturer/Marketer :

Xemex Life Sciences

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About O-Tab 20 Tablet

O-Tab 20 Tablet is used to treat gastroesophageal reflux disease (GERD), peptic ulcer (stomach or duodenal ulcer), and Zollinger-Ellison syndrome (overproduction of acid due to a pancreatic tumour). Normally, a thick layer of mucus protects the stomach against its own acid secretion. But, in the long run, it gets eroded by excessive stomach acid production, leading to complications like GERD, peptic ulcer, and Zollinger-Ellison syndrome.

O-Tab 20 Tablet contains omeprazole, which prevents the release of stomach acid and relieves symptoms such as food pipe lining inflammation (esophagitis), acid reflux, or heartburn.

O-Tab 20 Tablet may cause common side effects like stomach pain, gas formation (flatulence), nausea, vomiting, diarrhoea, and headache. These side effects are temporary and may resolve on their own. However, if the side effects persist or worsen, consult your doctor.

Before taking O-Tab 20 Tablet , inform your doctor if you are allergic to any of its components or to other proton pump inhibitors. Also, tell your doctor if you have stomach or intestinal cancer, severe liver problems, difficulty swallowing, bloody or black stools, unexplained weight loss, or if you will have an endoscopy in the future. Consult your doctor before taking O-Tab 20 Tablet if you are pregnant or breastfeeding.

Uses of O-Tab 20 Tablet

O-Tab 20 Tablet is used in the treatment of gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. The detailed uses of O-Tab 20 Tablet are as follows:

  • Gastroesophageal Reflux Disease (GERD) Treatment: O-Tab 20 Tablet is commonly used to treat GERD. It is a proton pump inhibitor (PPI) that reduces stomach acid production, thus providing relief from acid reflux symptoms.
  • Peptic Ulcer Treatment: O-Tab 20 Tablet is also used to treat ulcers in the stomach and intestine (duodenum). It is effective against ulcers associated with Helicobacter pylori infection and those caused by non-steroidal anti-inflammatory drugs (NSAIDs).
  • Zollinger-Ellison Syndrome Treatment: O-Tab 20 Tablet is also prescribed for Zollinger-Ellison syndrome to help control acid production and manage symptoms.
  • Hyperacidity Relief: O-Tab 20 Tablet helps to relieve hyperacidity by reducing the production of stomach acid.
  • Dyspepsia relief: O-Tab 20 Tablet provides relief from dyspepsia symptoms like bloating, heartburn, and stomach pain by reducing stomach acid secretion.
  • Preventive Therapy: O-Tab 20 Tablet is also used to prevent stomach ulcers, stress-related ulcers, and aspiration syndrome during anaesthesia (a condition where stomach contents accidentally enter the lungs).

Have a query?

Directions for Use

  • O-Tab 20 Tablet can be taken with or without food. However, it is recommended to take it 30-60 minutes before a meal, preferably in the morning, for optimal effectiveness.
  • It is typically administered once daily, but your doctor will determine the exact dose and timing based on your specific medical condition.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, break, or open it.

Medicinal Benefits

  • O-Tab 20 Tablet is effective in relieving symptoms of gastroesophageal reflux disease (heartburn), Zollinger-Ellison syndrome, and peptic ulcers (stomach or duodenal ulcers), as well as healing erosive esophagitis (inflammation of the food pipe).
  • O-Tab 20 Tablet contains omeprazole, which works by irreversibly blocking the proton pump gate (which secretes stomach acid).

How O-Tab 20 Tablet Works

O-Tab 20 Tablet contains omeprazole (a proton pump inhibitor), which helps reduce stomach acid by blocking the actions of an enzyme called H+/K+ ATPase (gastric proton pump). This proton pump lies in the stomach wall cells and is responsible for releasing gastric acid. O-Tab 20 Tablet prevents the release of stomach acid and relieves symptoms such as food pipe lining inflammation (esophagitis), acid reflux, or heartburn.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of O-Tab 20 Tablet

Do not take more than the prescribed dose of O-Tab 20 Tablet , as it may cause an overdose. The symptoms of an overdose include blurred vision, confusion, drowsiness, vomiting, nausea, sweating, fast or pounding heartbeat, flushing (feeling of warmth), headache, and dry mouth. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take O-Tab 20 Tablet if you are allergic to any of its components, other proton pump inhibitors, or if you are taking medications for HIV such as nelfinavir.
  • Inform your doctor if you have stomach or intestinal cancer, severe liver problems, difficulty swallowing, bloody or black stools, unexplained weight loss, hypomagnesemia (low blood magnesium levels), stomach problems (such as pain or indigestion), or will have an endoscopy in the future.
  • O-Tab 20 Tablet should not be given to patients suffering from Clostridium difficile-associated diarrhea.
  • Avoid prolonged use of O-Tab 20 Tablet , as it may increase the risk of osteoporosis-related fractures of the hip, wrist, or spine due to loss of magnesium.
  • Consult your doctor before taking O-Tab 20 Tablet if you are pregnant or breastfeeding.
  • O-Tab 20 Tablet should not be given to children under 1 year of age.

Drug-Drug Interactions

verifiedApollotooltip
OmeprazoleRilpivirine
Critical
OmeprazoleErlotinib
Critical

Drug-Drug Interactions

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OmeprazoleRilpivirine
Critical
How does the drug interact with O-Tab 20 Tablet:
Using rilpivirine together with O-Tab 20 Tablet can decrease the absorption and blood levels of rilpivirine.

How to manage the interaction:
Taking O-Tab 20 Tablet with Rilpivirine can cause an interaction, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
OmeprazoleErlotinib
Critical
How does the drug interact with O-Tab 20 Tablet:
O-Tab 20 Tablet can make Erlotinib less effective by reducing its absorption in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Taking O-Tab 20 Tablet and Erlotinib together is not recommended as it can result in an interaction; it should be taken only if a doctor has advised it. Do not stop using any medications without talking to a doctor.
OmeprazoleMesalazine
Severe
How does the drug interact with O-Tab 20 Tablet:
Co-administration of O-Tab 20 Tablet with mesalazine can decrease the effects of mesalazine.

How to manage the interaction:
There could be a possible interaction between Mesalazine and O-Tab 20 Tablet, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
OmeprazoleAcalabrutinib
Severe
How does the drug interact with O-Tab 20 Tablet:
O-Tab 20 Tablet, through decreasing stomach acidity, may interfere with the absorption of acalabrutinib capsules and reduce their effectiveness.

How to manage the interaction:
Although taking O-Tab 20 Tablet with acalabrutinib can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
OmeprazolePazopanib
Severe
How does the drug interact with O-Tab 20 Tablet:
O-Tab 20 Tablet may interfere with pazopanib absorption and reduces its effectiveness.

How to manage the interaction:
Although taking O-Tab 20 Tablet with pazopanib can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
OmeprazoleIsoniazid
Severe
How does the drug interact with O-Tab 20 Tablet:
When O-Tab 20 Tablet is taken with Isoniazid, it can increase the risk of side effects.

How to manage the interaction:
Co-administration of O-Tab 20 Tablet with Isoniazid can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without talking to a doctor.
OmeprazoleTacrolimus
Severe
How does the drug interact with O-Tab 20 Tablet:
Taking tacrolimus with O-Tab 20 Tablet may significantly increase the blood levels of tacrolimus, which may increase the risk of serious side effects (high sugars, infections, kidney problems, hyperkalemia - high blood levels of potassium).

How to manage the interaction:
Although taking O-Tab 20 Tablet with tacrolimus can lead to interaction, they can be taken if recommended by a doctor. However, consult the doctor if you experience irregular heart rhythm, palpitations (fast heartbeat), muscle spasm, tremor (shaking of hands & legs), and seizures(fits). Do not stop using any medications without talking to a doctor.
OmeprazoleCarbamazepine
Severe
How does the drug interact with O-Tab 20 Tablet:
Taking O-Tab 20 Tablet and carbamazepine may possibly reduce the effects of O-Tab 20 Tablet, which could reduce its capacity to treat the condition.

How to manage the interaction:
Although taking O-Tab 20 Tablet and carbamazepine together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without consulting a doctor.
OmeprazoleClopidogrel
Severe
How does the drug interact with O-Tab 20 Tablet:
When taken together O-Tab 20 Tablet can lower the levels of Clopidogrel in the blood, which can result in a decreased effectiveness of clopidogrel.

How to manage the interaction:
Taking O-Tab 20 Tablet and clopidogrel together has an interaction, but you can take these medications together if a doctor has advised it. Do not stop using any medications without talking to a doctor.
OmeprazoleItraconazole
Severe
How does the drug interact with O-Tab 20 Tablet:
Co-administration of O-Tab 20 Tablet with itraconazole can lessen the amount or effects of itraconazole.

How to manage the interaction:
Although taking Itraconazole along with O-Tab 20 Tablet can cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid intake of acid or heartburn-triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes, and high-fat and spicy foods.
  • Before going to sleep, try to raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows; instead, one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.
  • Avoid taking alcohol and smoking cigarettes. Alcohol can raise the level of production of stomach acid, leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter) which prevents backflow of the stomach acid back into the food pipe.
  • Include high-fibre containing foods, berries, cherries, leafy green veggies (kale, spinach), and black pepper in your meal. These foods are rich in antioxidants, calcium, and vitamin B12, which can help mitigate the long-term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics, which help in the prevention of excess stomach acid production. Cranberry juice can be beneficial in peptic ulcer and H. pylori infection.
  • Avoid sitting continuously, as it can increase stomach acid production. Try to take a break of 5 minutes in 1 hour by brisk walking or stretching.

Habit Forming

No

Therapeutic Class

ANTACIDS

All Substitutes & Brand Comparisons

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Alcohol

Caution

Drinking alcohol with O-Tab 20 Tablet may cause dehydration and elevate the level of stomach acid, thereby decreasing its efficiency. So, try to avoid or limit alcohol and contact the doctor before intake of O-Tab 20 Tablet .

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Pregnancy

Consult your doctor

It is unknown whether O-Tab 20 Tablet affects the baby or not. Please consult your doctor before taking O-Tab 20 Tablet if you are pregnant or planning to become pregnant.

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Breast Feeding

Consult your doctor

It is unknown whether O-Tab 20 Tablet passes into the breast milk. Please consult your doctor before taking O-Tab 20 Tablet if you are breastfeeding.

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Driving

Caution

O-Tab 20 Tablet may cause dizziness, sleepiness, or blurred vision. If you experience these symptoms, refrain from driving or operating heavy machinery until you have fully recovered.

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Liver

Caution

O-Tab 20 Tablet should be taken with caution, especially if you have a history of liver diseases/conditions.

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Kidney

Caution

O-Tab 20 Tablet should be taken with caution, especially if you have a history of kidney diseases/conditions.

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Children

Caution

O-Tab 20 Tablet should not be given to children under 1 year of age. O-Tab 20 Tablet is generally safe to use in children over 1 year when prescribed by a doctor.

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Heart

O-Tab 20 Tablet can generally be used even if you have heart problems, but only under your doctor’s guidance. Consult your doctor if you have any concerns regarding it.

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Geriatrics

Safe if prescribed

O-Tab 20 Tablet can be safely used in elderly patients with proper monitoring and individualised care. Long-term use should be reassessed regularly by a healthcare provider.

FAQs

O-Tab 20 Tablet is used to treat gastroesophageal reflux disease (GERD), peptic ulcer (stomach or duodenal ulcer), and Zollinger-Ellison syndrome (overproduction of acid due to a pancreatic tumor).

O-Tab 20 Tablet contains omeprazole (a proton pump inhibitor), which helps reduce stomach acid by blocking the action of an enzyme called H+/K+ ATPase (the gastric proton pump). This proton pump lies in the stomach wall cells and is responsible for releasing gastric acid. O-Tab 20 Tablet prevents the release of stomach acid and relieves symptoms such as food pipe lining inflammation (esophagitis), acid reflux, or heartburn.

Prolonged intake of O-Tab 20 Tablet may lead to atrophic gastritis (inflammation of stomach cells), vitamin B12 deficiency, and weakening of bones or osteoporosis (loss of calcium, magnesium, and vitamin D). Your doctor may prescribe calcium, vitamin D, or haemoglobin-enhancing medications to cope with long-term side effects.

No. O-Tab 20 Tablet is not prescribed for stomach cancer. O-Tab 20 Tablet is only indicated for the treatment of hyperacidity, acid reflux symptoms (GERD), heartburn and Zollinger-Ellison syndrome.

No. Gas and acidity are two different common discomforts. Acidity is caused when the improper functioning of the valve (sphincter) is located at the junction of the stomach and the food pipe. As a result, stomach acid backflows and enters the upper part of the food pipe, causing heartburn. On the other hand, gas is the result of the digestion of food and drinks, eliminating gases like carbon dioxide, hydrogen, nitrogen, methane, etc., from the body.

Country of origin

India

Manufacturer/Marketer address

Dash Sahi Sankar Pur Cuttack Or 753021 In
Other Info - OTA0011

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Nov 18, 2025 | 7:34 AM IST

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Reference

  1. https://www.drugs.com/omeprazole.html
  2. https://medlineplus.gov/druginfo/meds/a693050.html
  3. https://assets.hpra.ie/products/Human/19006/Leaflet-2191137-11072017125746-636353746684687500.pdf
  4. https://rwandafda.gov.rw/wp-content/uploads/2023/03/OMLINK-20-Capsules-Omeprazole-USP-20mg-Omeprazole-Pellets-7.15-PIL.pdf
  5. https://www.nps.org.au/assets/medicines/928c8260-b5d1-4989-838e-a53300ff645e.pdf
  6. https://www.drreddys.com/media/109870/omeprazole-20mg-pil.pdf
  7. https://www.nhs.uk/medicines/omeprazole/
  8. https://www.medicines.org.uk/emc/product/663/pil

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