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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:36 PM IST
Nupenzo 40 mg Injection 2 ml belongs to a class of medications called antipsychotics. It contains flupentixol which is used to treat schizophrenia (a mental illness) and other psychotic disorders. This medicine works by inhibiting the dopamine (chemical messenger) receptors in the brain and thereby helps improve feelings, disturbing thoughts, and behaviour.
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Composition

FLUPENTIXOL-40MG

Manufacturer/Marketer

Erikson Pharma

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Nupenzo 40 mg Injection 2 ml

Nupenzo 40 mg Injection 2 ml belongs to a class of medications called antipsychotics used to treat schizophrenia (a mental illness) and other psychotic disorders. Schizophrenia is a mental disorder that affects the ability of a person to feel, think and behave clearly.

Nupenzo 40 mg Injection 2 ml contains Flupentixol which works by inhibiting the dopamine (chemical messenger) receptors in the brain. Dopamine is involved in regulating mood, behaviour, and emotions. Thereby, Nupenzo 40 mg Injection 2 ml helps in controlling psychotic illness by preventing the overactivity of dopamine in the brain. Thus, it helps in improving feelings, disturbing thoughts, and behaviour.

Nupenzo 40 mg Injection 2 ml will be administered by a healthcare professional; do not self-administer. Some people may experience dry mouth, drowsiness, rigidity of the whole body, muscle spasms, headache, changes in weight, dizziness, insomnia (difficulty in sleeping), nervousness, or depression. Most of these side effects of Nupenzo 40 mg Injection 2 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

Please tell your doctor if you are allergic to Flupentixol or other medicines. Nupenzo 40 mg Injection 2 ml is not recommended for children and adolescents. Nupenzo 40 mg Injection 2 ml should be used with caution in elderly patients above 65 years as there is an increased risk of adverse reactions. Using Nupenzo 40 mg Injection 2 ml in the third trimester may cause adverse effects in the baby, such as breathing problems, muscle stiffness or weakness, shaking, etc. Nupenzo 40 mg Injection 2 ml may be excreted in human milk. Therefore, if you are pregnant or breastfeeding, inform your doctor before taking Nupenzo 40 mg Injection 2 ml. Do not consume alcohol with Nupenzo 40 mg Injection 2 ml as it may increase drowsiness. Drive only if you are alert, as Nupenzo 40 mg Injection 2 ml may cause dizziness, blurred vision, or drowsiness. 

Uses of Nupenzo 40 mg Injection 2 ml

Treatment of Schizophrenia

Medicinal Benefits

Nupenzo 40 mg Injection 2 ml contains Flupentixol used to treat schizophrenia (a mental illness) and other psychotic disorders. Nupenzo 40 mg Injection 2 ml inhibits the dopamine (chemical messenger) receptors in the brain. Dopamine is involved in regulating mood, behaviour, and emotions. Thereby, Nupenzo 40 mg Injection 2 ml helps in controlling psychotic illness by preventing the overactivity of dopamine in the brain. Thus, it helps in improving feelings, disturbing thoughts, and behaviour.

Directions for Use

Nupenzo 40 mg Injection 2 ml will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Nupenzo 40 mg Injection 2 ml

  • Dry mouth
  • Drowsiness
  • Rigidity of the whole body
  • Muscle spasm
  • Headache
  • Changes in weight
  • Dizziness
  • Insomnia (difficulty in sleeping)
  • Nervousness
  • Depression

Drug Warnings

Please tell your doctor if you are allergic to Flupentixol or other medicines. If you have low potassium or magnesium in your blood, inform your doctor before taking Nupenzo 40 mg Injection 2 ml. Nupenzo 40 mg Injection 2 ml is not recommended for children and adolescents. Nupenzo 40 mg Injection 2 ml should be used with caution in elderly patients above 65 years as there is an increased risk of adverse reactions. Using Nupenzo 40 mg Injection 2 ml in the third trimester may cause adverse effects in the baby, such as breathing problems, muscle stiffness or weakness, shaking, etc. Nupenzo 40 mg Injection 2 ml may be excreted in human milk. Therefore, if you are pregnant or breastfeeding, inform your doctor before taking Nupenzo 40 mg Injection 2 ml. Inform your surgeon, anesthetist, or dentist before any surgery that you are on treatment with Nupenzo 40 mg Injection 2 ml. Do not consume alcohol with Nupenzo 40 mg Injection 2 ml as it may increase drowsiness. Drive only if you are alert, as Nupenzo 40 mg Injection 2 ml may cause dizziness, blurred vision, or drowsiness.

Drug Interactions

Drug-Drug Interaction: Nupenzo 40 mg Injection 2 ml may interact with heart-related medicines (quinidine, amiodarone, sotalol, dofetilide, digoxin), gastroprokinetic agent (cisapride), antimanic drug (lithium), antibiotics (erythromycin, moxifloxacin), tricyclic antidepressants, other antipsychotics, blood thinner (warfarin), medicines that make you feel drowsy, antiemetic (metoclopramide), antiparkinson drug (levodopa), appetite suppressant (sibutramine), antidiabetics, anticonvulsants, steroid (prednisolone), high blood pressure lowering medicines (hydralazine, doxazosin, guanethidine, methyldopa, clonidine) and hormone (epinephrine).

Drug-Food Interaction: Nupenzo 40 mg Injection 2 ml may interact with alcohol. Therefore, avoid intake of alcohol while taking Nupenzo 40 mg Injection 2 ml as it may increase drowsiness.

Drug-Disease Interaction: If you have fits, asthma, bronchitis, serious blood circulation problems, potassium or magnesium in the blood, enlarged prostate, phaeochromocytoma (tumor in the adrenal gland), glaucoma (increased pressure in the eye), high blood pressure, Parkinson’s disease, diabetes, blood clots, cancer, myasthenia gravis (muscle weakness), have a family history of irregular heartbeats or blood clots, liver, kidney, heart or thyroid problems, inform your doctor before taking Nupenzo 40 mg Injection 2 ml. 

Drug-Drug Interactions Checker List

  • QUINIDINE
  • AMIODARONE
  • SOTALOL
  • DOFETILIDE
  • DIGOXIN
  • CISAPRIDE
  • LITHIUM
  • ERYTHROMYCIN
  • MOXIFLOXACIN
  • WARFARIN
  • METOCLOPRAMIDE
  • LEVODOPA
  • SIBUTRAMINE
  • PREDNISOLONE
  • HYDRALAZINE
  • DOXAZOCIN
  • GUANETHIDINE
  • METHYLDOPA
  • CLONIDINE
  • EPINEPHRINE

Habit Forming

No

Diet & Lifestyle Advise

  • Do regular exercise and maintain a healthy body weight.
  • Maintain a diet rich in fruits, vegetables and whole grains. 
  • Follow a regular sleep pattern. Do not take a nap during day time. 
  • Avoid watching tv, using mobiles or laptops just before bedtime.
  • Avoid consumption of alcohol as it may increase drowsiness.

Special Advise

Certain blood tests are recommended while taking Nupenzo 40 mg Injection 2 ml to monitor the level of Nupenzo 40 mg Injection 2 ml in blood if you have liver problems.

Disease/Condition Glossary

Schizophrenia: It is a mental disorder that impairs a person's ability to feel, think, and behave clearly. Hallucinations thought or movement disorders, delusions (misbelief), lack of emotion, sleep problems, isolating oneself from family and friends, and difficulty performing daily activities are some of the symptoms.

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Alcohol

Unsafe

Avoid consumption of alcohol with Nupenzo 40 mg Injection 2 ml as it may increase drowsiness and other adverse effects.

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Pregnancy

Caution

Nupenzo 40 mg Injection 2 ml is not recommended during pregnancy, especially in the first and third trimesters, unless it is clearly necessary. It may cause adverse effects in the baby, such as muscle stiffness, shaking, sleepiness, weakness, breathing problems and difficulty in the foetus. Therefore, if you are pregnant or planning pregnancy, please inform your doctor before taking Nupenzo 40 mg Injection 2 ml.

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Breast Feeding

Caution

If you are breastfeeding, please inform your doctor before receiving Nupenzo 40 mg Injection 2 ml.

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Driving

Caution

Nupenzo 40 mg Injection 2 ml may cause dizziness, drowsiness or blurred vision in some people. Therefore, avoid driving if you feel dizzy, drowsy, or experience any vision problems after taking Nupenzo 40 mg Injection 2 ml.

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Liver

Caution

Take Nupenzo 40 mg Injection 2 ml with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required. If you have liver problems, your doctor may monitor levels of Flupentixol in your blood.

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Kidney

Caution

If you have kidney problems, inform your doctor before taking Nupenzo 40 mg Injection 2 ml. Your doctor may adjust the dose of this medicine as necessary.

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Children

Unsafe

Nupenzo 40 mg Injection 2 ml is not recommended for children and adolescents as safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

B-81,Nehru Nagar,Jaipur,Rajasthan,India
Other Info - NUP0058

Author Details

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FAQs

Nupenzo 40 mg Injection 2 ml is an antipsychotic medicine used in the treatment of schizophrenia (a mental illness) and other psychotic disorders.
Nupenzo 40 mg Injection 2 ml contains Flupentixol which works by inhibiting the dopamine (chemical messenger) receptors in the brain. Dopamine is involved in regulating mood, behaviour and emotions. Thereby, Nupenzo 40 mg Injection 2 ml helps in controlling psychotic illness by preventing the overactivity of dopamine in the brain. Thus, it helps in improving feelings, disturbed thoughts and behaviour.
Nupenzo 40 mg Injection 2 ml should be used with caution in asthma patients as it may increase the risk of severe adverse effects. Therefore, inform your doctor if you have asthma or other breathing problems before taking Nupenzo 40 mg Injection 2 ml.
Nupenzo 40 mg Injection 2 ml may not be recommended to take before surgery. However, inform your surgeon, anaesthetist or dentist before any surgery that you are on treatment with Nupenzo 40 mg Injection 2 ml as it may increase the effects of muscle relaxing drugs, general anaesthesia and drugs used to prevent blood clots.
Nupenzo 40 mg Injection 2 ml may affect fertility as it reduces sexual activity. However, it is a temporary effect. Please consult a doctor if you are planning for pregnancy before taking Nupenzo 40 mg Injection 2 ml.
Nupenzo 40 mg Injection 2 ml should be used with caution in patients suffering from fits as it may worsen the condition. Therefore, inform your doctor if you have a history of fits before taking Nupenzo 40 mg Injection 2 ml.
You are not recommended to take Nupenzo 40 mg Injection 2 ml with levodopa (antiparkinson drug) as it may decrease the effectiveness of levodopa and increase the risk of adverse effects such as low blood pressure, drowsiness, light-headedness and dizziness. However, please consult your doctor before using Nupenzo 40 mg Injection 2 ml with any other medicines.

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