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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Nuparp 300 Tablet is indicated in the treatment of ovarian, fallopian tube, and primary peritoneal cancer. It contains Rucaparib, which works by blocking an enzyme that repairs damaged DNA in cancer cells, resulting in their death. Thus, it kills cancer cells and helps treat cancer. In some cases, it may cause side effects such as fatigue, nausea, vomiting, diarrhoea, and decreased or loss of appetite.

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Composition :

RUCAPARIB-300MG

Manufacturer/Marketer :

Zydus Cadila

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Nuparp 300 Tablet

Nuparp 300 Tablet belongs to the group of anti-cancer medicines called PARP (poly adenosine diphosphate-ribose polymerase) indicated in the treatment of ovarian cancer, fallopian tube, and primary peritoneal cancer. It is also indicated in the treatment of prostate cancer that has spread to other areas in the body in people with a specific gene who have received other treatments.

Nuparp 300 Tablet contains Rucaparib, which works by blocking an enzyme that repairs damaged DNA in cancer cells, resulting in their death. Thereby, it kills cancer cells and helps treat cancer.

In some cases, Nuparp 300 Tablet may cause side effects such as fatigue, nausea, vomiting, diarrhoea, decreased or loss of appetite. Most of these side effects may not require medical attention and resolve gradually over time. However, if any of the side effects persist or worsen, inform your doctor.

Let the doctor know if you are allergic to any of the components in Nuparp 300 Tablet . Nuparp 300 Tablet is not recommended for use in children as the safety and effectiveness have not been established. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Nuparp 300 Tablet

Treatment of Ovarian cancer, Fallopian tube cancer, Primary peritoneal cancer and Prostate cancer

Directions for Use

Swallow the medicine as a whole with water; do not crush or chew it.

Medicinal Benefits

Nuparp 300 Tablet belongs to the group of anti-cancer medicines called PARP (poly adenosine diphosphate-ribose polymerase) indicated in the treatment of prostate cancer. It is also used to help maintain the response to other treatments for certain types of ovarian cancer, fallopian tube, and primary peritoneal cancer that have returned in adults who have partially or completely responded to other chemotherapy treatments and in people with a specific gene who have received treatment with at least two other chemotherapy treatments. Nuparp 300 Tablet contains Rucaparib, which works by blocking an enzyme that repairs damaged DNA in the cancer cells, resulting in their death. Thereby, it kills cancer cells and helps treat cancer. 

How Nuparp 300 Tablet Works

Nuparp 300 Tablet contains Rucaparib, which works by blocking an enzyme that repairs damaged DNA in cancer cells, resulting in their death. Thereby, it kills cancer cells and helps treat cancer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Nuparp 300 Tablet

Ovarian cancer:

  • Nausea
  • Vomiting
  • Tiredness
  • Stomach pain
  • Loss of appetite
  • Diarrhoea
  • Dizziness
  • Sunburn
  • Heartburn
  • Difficulty breathing

Prostate cancer:

  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Fatigue
  • Anaemia
  • Decreased appetite

What if I have taken an overdose of Nuparp 300 Tablet

Do not take more than prescribed dose. Using more medication will not improve your symptoms; rather they may cause poisoning or serious side-effects. If you suspect that you may have overdosed of Nuparp 300 Tablet , please go to the emergency department of the closest hospital or nursing home.

Drug Warnings

Do not take Nuparp 300 Tablet if you are allergic to any of its components or if you are pregnant or breastfeeding. Nuparp 300 Tablet may cause serious side effects like bone marrow problems called Myelodysplastic Syndrome (MDS) or a type of cancer of the blood called Acute Myeloid Leukemia (AML). Seek immediate medical attention if you experience weakness, weight loss, fever, frequent infections, blood in urine or stools, feeling very tired, shortness of breath, and bleeding or bruising more easily. Consult your doctor immediately if you become pregnant during treatment with Nuparp 300 Tablet . Let your doctor know if you are taking any other medicines, including supplements and herbal products.

Drug-Drug Interactions

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RucaparibZiprasidone
Critical
RucaparibGatifloxacin
Severe

Drug-Drug Interactions

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RucaparibZiprasidone
Critical
How does the drug interact with Nuparp 300 Tablet 60's:
Coadministration of Nuparp 300 Tablet 60's and Ziprasidone may increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Nuparp 300 Tablet 60's with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
RucaparibGatifloxacin
Severe
How does the drug interact with Nuparp 300 Tablet 60's:
Taking Gatifloxacin with Nuparp 300 Tablet 60's can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Gatifloxacin with Nuparp 300 Tablet 60's together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RucaparibPirfenidone
Severe
How does the drug interact with Nuparp 300 Tablet 60's:
Taking Pirfenidone with Nuparp 300 Tablet 60's can increase the risk or severity of its side effects such as liver disease or gastric problems.

How to manage the interaction:
Co-administration of Pirfenidone with Nuparp 300 Tablet 60's can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately.
RucaparibCladribine
Severe
How does the drug interact with Nuparp 300 Tablet 60's:
Taking Nuparp 300 Tablet 60's with Cladribine can increase the risk of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Cladribine and Nuparp 300 Tablet 60's, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate. Do not stop using any medications without a doctor's advice.
RucaparibMoxifloxacin
Severe
How does the drug interact with Nuparp 300 Tablet 60's:
Using moxifloxacin together with Nuparp 300 Tablet 60's can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Moxifloxacin and Nuparp 300 Tablet 60's, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - like a fast or irregular heartbeat, severe or long-lasting diarrhea, vomiting, complications, sudden feeling dizzy or lightheaded, fainting, difficulty breathing, or feeling your heart beating fast - make sure to call your doctor right away. Do not stop using any medications without a doctor's advice.
RucaparibInfliximab
Severe
How does the drug interact with Nuparp 300 Tablet 60's:
When Nuparp 300 Tablet 60's is taken with Infliximab, can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Infliximab with Nuparp 300 Tablet 60's can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RucaparibSotalol
Severe
How does the drug interact with Nuparp 300 Tablet 60's:
Using sotalol together with Nuparp 300 Tablet 60's can increase the risk or severity of irregular heart rhythms which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Nuparp 300 Tablet 60's, you can take these medicines together if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations consult a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain a proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables, fruits, herbs, and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Nuparp 300 Tablet Substitute

Substitutes safety advice
  • Ruparib 300 Tablet 60's

    698.32per tablet
  • Lucaparib 300 Tablet 60's

    756.45per tablet
  • Rucaza 300 Tablet 60's

    646.45per tablet
  • Rucaven 300 mg Tablet 60's

    900.00per tablet
  • Bdparib 300 Tablet 60's

    900.00per tablet
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Alcohol

Consult your doctor

It is not known whether Nuparp 300 Tablet interacts with alcohol. Please consult your doctor.

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Pregnancy

Unsafe

Nuparp 300 Tablet should not be used during pregnancy as it may harm your unborn baby.

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Breast Feeding

Unsafe

Avoid breastfeeding whilst on treatment with Nuparp 300 Tablet and for at least two weeks after the last dose.

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Driving

Caution

In some cases, Nuparp 300 Tablet may cause tiredness. So, drive or operate machinery only if you are alert.

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Liver

Consult your doctor

If you have a history of liver disease, please inform your doctor before taking Nuparp 300 Tablet .

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Kidney

Consult your doctor

If you have a history of kidney disease, please inform your doctor before taking Nuparp 300 Tablet .

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Children

Unsafe

Nuparp 300 Tablet is not recommended for children as the safety and effectiveness have not been established.

FAQs

Nuparp 300 Tablet is used treat Ovarian cancer, Fallopian tube cancer, Primary peritoneal cancer and Prostate cancer.
Nuparp 300 Tablet works by blocking an enzyme that repairs damaged DNA in the cancer cells, resulting in their death. Thereby, it helps treat cancer.
Nuparp 300 Tablet may make your skin sensitive to sunlight. Therefore, avoid unnecessary or prolonged exposure to sunlight. Also, wear protective clothing and apply sunscreen.
If you experience nausea, vomiting, diarrhoea, or abdominal pain, consult your doctor, as these may be signs that Nuparp 300 Tablet is affecting your stomach or bowels.

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad €“ 380015 Gujarat, India.
Other Info - NUP0077

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