Numlo-TM Tablet belongs to the class of medicines called ‘anti-hypertensive’ primarily used to treat hypertension (high blood pressure). Hypertension or high blood pressure is a chronic condition in which the blood's force against the artery wall is high. As a result, it leads to heart disease, irregular heartbeat and other complications.

Numlo-TM Tablet is a combination of two medicines include: S-Amlodipine and Telmisartan, which are antihypertensive medicines. S-amlodipine is a calcium channel blocker and works by relaxing and widening the blood vessels.  It is equally efficacious at a half dose with better tolerability and fewer side effects, including peripheral oedema, than amlodipine. Telmisartan is an angiotensin II receptor antagonist that lowers blood pressure and increases blood flow by preventing blood vessel narrowing. It is used to lower the chances of stroke, heart attack and death. Altogether, Numlo-TM Tablet helps to lower high blood pressure, chest pain (angina) and other conditions caused by coronary artery disease.

Take Numlo-TM Tablet as prescribed by your doctor. You are advised to take Numlo-TM Tablet as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain side effects, dizziness, stomach pain, nausea, constipation, double vision, muscle cramps, swollen ankles, oedema (fluid retention), and hypotension (low blood pressure). Most of these side effects of Numlo-TM Tablet do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

If you are known to be allergic to Numlo-TM Tablet or any other medicines, please inform your doctor. Pregnant or breastfeeding women should discontinue this Numlo-TM Tablet because it can cause injury and death to the developing fetus. Please do not stop taking Numlo-TM Tablet on your own, which may lead to the recurrence of symptoms or worsen the condition. Rise slowly if you have been sitting or lying down, as it may cause you to feel lightheaded or weak, especially when you stand up. Avoid potassium supplements with Numlo-TM Tablet as it may lead to high potassium levels in the blood. It is advised to drive with caution after taking Numlo-TM Tablet as it usually causes drowsiness and affects the driving ability.

Numlo-TM Tablet is a combination of two medicines, namely, S-amlodipine and Telmisartan, primarily taken to prevent hypertension (high blood pressure). S-amlodipine belongs to a group of drugs called calcium channel blocker that dilates (widen) blood vessels and increase blood flow. S-amlodipine is equally effective at a half dose with better tolerability, and lesser side effects, including peripheral oedema, than amlodipine. Telmisartan is an angiotensin receptor blocker (ARB) that lowers increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). It allows these constricted blood vessels to relax and, therefore, helps lower high blood pressure. It is used to lower the chances of stroke, heart attack and death. Collectively, Numlo-TM Tablet helps to lower high blood pressure, chest pain (angina), and other conditions caused by coronary artery disease.

• Dizziness
• Sleepiness
• Stomach pain
• Nausea
• Constipation
• Double vision
• Muscle cramps
• Swollen ankles
• Oedema (fluid retention)
• Hypotension (low blood pressure)

Don't stop taking Numlo-TM Tablet without talking to your doctor first. Stopping Numlo-TM Tablet abruptly may cause changes in your blood pressure and heart rhythm, cause chest pain or a heart attack. Your doctor will lower your dose gradually over a period of time to help prevent these symptoms. Numlo-TM Tablet should not be given to the people allergic to Numlo-TM Tablet or any of its ingredients, have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease. Do not take Numlo-TM Tablet if you are pregnant, planning to conceive, or breastfeeding. Numlo-TM Tablet is not recommended to children below 18 years. Numlo-TM Tablet can cause ankle or foot swelling, raise your legs while you are sitting down and talk to your doctor if it does not go away. Avoid potassium supplements with Numlo-TM Tablet as it may lead to high potassium levels in the blood. Do not consume alcohol with Numlo-TM Tablet as it may increase the risk of low blood pressure.

Drug-Drug Interaction: Numlo-TM Tablet may interact with other blood pressure treating medicines (ramipril, aliskiren, simvastatin, verapamil, diltiazem), antifungal (ketoconazole, itraconazole), medicines used to treat HIV infections (ritonavir¸ indinavir, nelfinavir, nevirapine), pain killers (ibuprofen, naproxen, aspirin), antibiotics (clarithromycin, erythromycin, telithromycin, rifampicin, rifabutin) a medicine used to treat heart failure and abnormal heart rhythms (digoxin), antiepileptics (phenobarbital, phenytoin, carbamazepine), bipolar disorder medication (lithium), and immunosuppressants (cyclosporine, tacrolimus).

Drug-Food Interaction: Numlo-TM Tablet severely interacts with grapefruit, grapefruit juices, and St. John’s wort (a plant used to treat depression). Hence it should not be taken with Numlo-TM Tablet . Minimize high potassium foods intake.

Drug-Disease Interaction: People with diabetes, hyperkalemia (high potassium levels in the blood), hypotension (low blood pressure), kidney and liver problems should consult the doctor before taking Numlo-TM Tablet .

• RAMIPRIL
• ALISKIREN
• SIMVASTATIN
• VERAMAPIL
• DILITAZEM
• KETOCONAZOLE
• ITRACONAZOLE
• RITONAVIR
• INDINAVIR
• NELFINAVIR
• NEVIRAPINE
• IBUPROFEN
• NAPROXEN
• ASPIRIN
• CLARITHROMYCIN
• ERYTHROMYCIN
• TELITHROMYCIN
• RIFAMPICIN
• RIFABUTIN
• DIGOXIN
• PHENOBARBITAL
• PHENYTOIN
• CARBAMAZEPINE
• LITHIUM
• CYCLOSPORINE
• TACROLIMUS

• ​​Keep your weight under control with BMI 19.5-24.9.

• Do regular physical activity or exercise for at least 150 minutes per week or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
• Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
• If you are taking alcohol, then only one serving for women and two servings for men is advisable.
• Quitting smoking is the best strategy to lower the risk of heart disease.
• Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
• Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
• Try to include heart-healthy omega 3 fatty acids containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil and coconut oil to lower your elevated blood pressure.

• Keep a check on your daily blood pressure, and if you notice any fluctuations, please consult a doctor. 
• Do not use potassium supplements or salt substitutes while using Numlo-TM Tablet unless your doctor has told you to do so.
• Numlo-TM Tablet may cause swelling in the ankles and feet, try to avoid sitting for long times or maintain limb elevation while sitting.

Blood pressure is the measurement of the force that our heart uses to pump blood to all parts of the body. Hypertension is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.