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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Nozen Plus Tablet is used to relieve pain. It contains Aceclofenac and Serratiopeptidase which work by blocking the release of chemical messengers that cause pain and preventing swelling. In some cases, this medicine may cause side effects such as nausea, vomiting, loss of appetite, heartburn, stomach pain, indigestion, and diarrhoea. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Consume Type :

ORAL

Return Policy :

Not Returnable

About Nozen Plus Tablet

Nozen Plus Tablet belongs to a group of medicines called 'Non-Steroidal Anti-Inflammatory Drugs' (NSAIDs) used to provide pain relief in various conditions including post-traumatic pain, low back pain, cervical pain, spondylitis, osteoarthritis, rheumatoid arthritis. Pain can be temporary (acute) or prolonged period (chronic) in nature. Acute pain is for a short time caused by damage to the tissues of the muscle, bone or organs. Chronic pain lasts for life long caused due to nerve damage, osteoarthritis and dental pain due to damage to the tooth nerve, infection, extraction or injury. 

Nozen Plus Tablet contains two medicines, namely Aceclofenac and Serratiopeptidase. Aceclofenac works by blocking the release of a chemical messenger called prostaglandin, produced by COX-2, responsible for pain, swelling and inflammation. On the other hand, Serratiopeptidase is a proteolytic enzyme that helps break the insoluble protein (fibrin) by-product of blood clot into smaller units. It also causes thinning of the fluids in the body due to injury, thereby making fluid drainage smoother in the swollen tissue. Together Nozen Plus Tablet is effective for relieving pain, especially in joint condition. 

You are advised to take Nozen Plus Tablet for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience nausea, vomiting, loss of appetite (feeling not hungry), heartburn, stomach pain, indigestion, diarrhoea. Most of these side effects of Nozen Plus Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not take Nozen Plus Tablet if you are pregnant or breastfeeding unless prescribed by the doctor. Nozen Plus Tablet may cause drowsiness and dizziness, so drive with caution. Nozen Plus Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol, and Nozen Plus Tablet as it could lead to increased drowsiness and dizziness; it might also increase stomach bleeding risk. Nozen Plus Tablet should not be given to children as the safety and effectiveness were not established. 

Uses of Nozen Plus Tablet

Treatment of Musculoskeletal pain, Gout, Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Nozen Plus Tablet is used to provide pain relief in various conditions including post-traumatic pain, low back pain, cervical pain, spondylitis (inflammation in spinal bones), osteoarthritis (lifelong joint pain and stiffness), rheumatoid arthritis (joint pain and damage throughout the body), and migraine. Nozen Plus Tablet plays a vital role in reducing pain and inflammation by blocking the release of chemical messengers that cause pain and inflammation. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site. Serratiopeptidase is a proteolytic enzyme that helps break the insoluble protein (fibrin) by-product of blood clots into smaller units. It also causes thinning of the fluids in the body due to injury, thereby making fluid drainage smoother in the swollen tissue.

How Nozen Plus Tablet Works

Nozen Plus Tablet contains two medicines, namely Aceclofenac and Serratiopeptidase. Aceclofenac works by blocking the release of a chemical messenger called prostaglandin, produced by COX-2, responsible for pain, swelling and inflammation. On the other hand, Serratiopeptidase is a proteolytic enzyme that helps break the insoluble protein (fibrin) by-product of blood clot into smaller units. It also causes thinning of the fluids in the body due to injury, thereby making fluid drainage smoother in the swollen tissue. Together Nozen Plus Tablet is effective for relieving pain, especially in joint condition.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Nozen Plus Tablet

  • Nausea
  • Vomiting
  • Loss of appetite
  • Heartburn
  • Stomach pain
  • Indigestion
  • Diarrhoea

What if I have taken an overdose of Nozen Plus Tablet

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Do not take Nozen Plus Tablet if you are allergic to Nozen Plus Tablet or other painkillers. Nozen Plus Tablet should not be taken in the conditions like stomach ulcers, bleeding problems, clotting problems, or severe heart, liver, or kidney problems. Inform your doctor before taking Nozen Plus Tablet if you have or had disorders of the stomach, blood circulation problems to the brain, asthma, angioedema (swelling under the skin), skin rashes, diabetes, high blood pressure, auto-immune diseases, and connective tissue diseases. Stop taking Nozen Plus Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Inform your doctor if you are recovering from major surgery or if you are more than 65 years of age. Do not take Nozen Plus Tablet if you are pregnant or breastfeeding unless prescribed. Nozen Plus Tablet may cause drowsiness and dizziness, so drive only if you are alert. Nozen Plus Tablet should not be given to children as safety has not been established. Avoid consuming alcohol along with Nozen Plus Tablet as it could lead to increased drowsiness and can increase the risk of stomach bleeding.

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listen to soothing music.
  • Acupuncture, massage, and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANALGESICS

Nozen Plus Tablet Substitute

Substitutes safety advice
  • Anclof S 100mg/10mg Tablet

    5.40per tablet
  • Afesan S 100mg/10mg Tablet

    11.34per tablet
  • Mezer 100mg/10mg Tablet

    11.25per tablet
  • Cuflam SP 100mg/10mg Tablet

    8.01per tablet
  • Sun S 100mg/10mg Tablet

    5.94per tablet
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Nozen Plus Tablet to avoid unpleasant side-effects like increased risk of stomach bleeding.

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Pregnancy

Unsafe

The use of Nozen Plus Tablet may impair female fertility and is not recommended in pregnant women or those planning for pregnancy.

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Breast Feeding

Unsafe

Nozen Plus Tablet contains serratiopeptidase, which may pass into the breast milk. So, it is not recommended for nursing mothers.

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Driving

Unsafe

Nozen Plus Tablet may affect driving as it causes dizziness. So do not drive a motor vehicle or operate heavy machinery after taking Nozen Plus Tablet.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Nozen Plus Tablet should not be given to children as the safety and effectiveness were not established.

FAQs

Nozen Plus Tablet is used to relieve post-traumatic pain, low back pain, cervical pain, and pain associated with spondylitis, osteoarthritis, and rheumatoid arthritis.
Nozen Plus Tablet is a combination of two medicines that include aceclofenac and serratiopeptidase. Nozen Plus Tablet contains ‘aceclofenac’ which works by blocking the release of a chemical messenger called prostaglandin, produced by COX-2 in the brain, responsible for pain, swelling, and inflammation. On the other hand, Nozen Plus Tablet contains serratiopeptidase, which reduces swelling and inflammation through proteins' breakdown. Thus Nozen Plus Tablet helps to relieve musculoskeletal pain and in various joints conditions.
Do not take Nozen Plus Tablet for longer durations as it might increase the risk of heart problems and stomach bleeding. Do not exceed the dose and duration of treatment as prescribed by the doctor.
Diarrhea might be a side-effect of Nozen Plus Tablet. Drink enough fluids and eat fiber-rich food if you experience diarrhea. If you find blood in stools (tarry stools) or if you experience excess diarrhea consult your doctor. Do not take anti-diarrheal medicine on your own.
Ankylosing spondylitis is arthritis of the spine that can lead to the vertebrae's fusion, leading to pain and inflammation in the spine (vertebrae).
Avoid or limit consumption of alcohol with Nozen Plus Tablet as it increases the chances of stomach ulcers and bleeding. It may also lead to increased dizziness and drowsiness.
The most common side effects of Nozen Plus Tablet are nausea, vomiting, loss of appetite (feeling not hungry), heartburn, stomach pain, indigestion, diarrhea. Most of these side effects of Nozen Plus Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Serrapeptase is a proteolytic enzyme (protein breaking) derived from silkworms used to treat inflammation and pain following surgery, joint pain, dental surgery and other medical purposes.
No, Nozen Plus Tablet is not addictive. It is not a habit-forming medication.
Yes, Nozen Plus Tablet may provide relief from toothache due to infection, damage to the tooth nerve, extraction or injury. Nozen Plus Tablet reduces pain and inflammation by inhibiting the production of substances in the body that cause pain and inflammation.

Country of origin

India
Other Info - NO77394

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