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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Novarapid Penfil 100 mg Injection is used for the treatment of diabetes mellitus in both children (above two years of age) and adults. It typically begins working after 10-20 minutes and will last for between 3 and 5 hours. Due to this short action, it should normally be taken in combination with intermediate-acting or long-acting insulin preparations. It contains Insulin aspart, which works by ensuring rapid and consistent sugar control. It is a fast-acting form of insulin that helps lower blood sugar levels after food intake. It prevents the risk of having severe complications of diabetes. It stimulates the recovery of sugar in muscle and fat cells and thus suppresses sugar production in the liver. It may cause common side effects such as hypokalaemia (low potassium), hypoglycaemia (low blood sugar level), local injection site reactions, lipodystrophy (fat deposition under the skin), rash, and itching at the injection site. Along with this medicine, you should take a healthy diet, exercise regularly, and maintain weight as advised by your doctor.

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Manufacturer/Marketer :

Novo Nordisk India Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Novarapid Penfil 100 mg Injection

Novarapid Penfil 100 mg Injection is a rapid-acting human insulin analogue for the treatment of diabetes mellitus in both children (above two years of age) and adults. The active ingredient in Novarapid Penfil 100 mg Injection is insulin aspart. Diabetes is a medical condition where your body does not produce enough insulin to control your blood sugar level. Treatment with Novarapid Penfil 100 mg Injection helps to prevent complications from your diabetes.

Novarapid Penfil 100 mg Injection contains Insulin Aspart, it is extremely fast-acting and works rapidly to normalise blood sugar levels. It typically begins working after 10-20 minutes and lasts between 3 and 5 hours. Due to this short action, Novarapid Penfil 100 mg Injection should usually be taken with intermediate-acting or long-acting insulin preparations. Novarapid Penfil 100 mg Injection works by ensuring rapid and consistent sugar control. Novarapid Penfil 100 mg Injection is a fast-acting form of insulin that helps lower blood sugar levels after food intake. It prevents the risk of having severe complications of diabetes. It stimulates the recovery of sugar in muscle and fat cells and thus suppresses sugar production in the liver.

Your doctor will advise you on how to use Novarapid Penfil 100 mg Injection. It should be administered at least 5-10 minutes before the meal or within 20 minutes after you start having a meal. The common side effects of Novarapid Penfil 100 mg Injection are hypokalaemia (low potassium), hypoglycaemia (low blood sugar level), local injection site reactions, lipodystrophy (fat deposition under the skin), rash, and pruritus (itch skin), which may occur at the injection site. Most of these side effects of Novarapid Penfil 100 mg Injection do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.

Try not to stop taking Novarapid Penfil 100 mg Injection of your own. Let your doctor know about this, as it may cause withdrawal symptoms. Do not take Novarapid Penfil 100 mg Injection if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs. Along with Novarapid Penfil 100 mg Injection, you should take a healthy diet, exercise regularly, and maintain weight as your doctor advises. Novarapid Penfil 100 mg Injection is a cold chain medicine, so it must be stored in the refrigerator between 2-8 degrees Celsius; otherwise, its efficiency might get lost. Do not store it in the fridge freezer.

Uses of Novarapid Penfil 100 mg Injection

Treatment of Diabetes (Type 1 diabetes mellitus, Type 2 diabetes mellitus).

Directions for Use

Novarapid Penfil 100 mg Injection is administered 5-10 minutes before taking meal subcutaneously (SC) in the abdomen or thigh region. It can also be given intravenously (IV) with 0.9% sodium chloride infusion. However, subcutaneous injection of Novarapid Penfil 100 mg Injection in the abdomen region ensures faster absorption than other injection sites. Novarapid Penfil 100 mg Injection is usually given once or twice daily when both rapid and prolonged insulin effects are desired. In the initial requirement, the dose requirement is generally between 0.3 and 1.0 IU/kg per day. An injection of Novarapid Penfil 100 mg Injection should be followed within 30 minutes by a meal or snack containing sugar/glucose (carbohydrates). If you are not well trained to self-administer Novarapid Penfil 100 mg Injection, ask a healthcare professional to administer it.

Procedure for self-injecting insulin:

• You should wash your hands first before injecting insulin.

• Then roll the insulin bottle and wipe the bottle top.

• Now pull the plunger of the syringe down to an appropriate number of units your doctor has prescribed.

• Push the needle into the bottle and push the syringe plunger down.

• Now, once again, pull the plunger down to an appropriate number of units as the doctor prescribes.

• Pick the injection site and wipe it with an alcohol swab. Now, pinch up the skin, push the needle into the skin and then push the plunger in.

• The needle should be kept under the skin for at least 6 seconds to make sure the entire dose is injected.

• After injecting the insulin, pull out the needle and dispose of the syringe safely. And then you can have a meal or snack.

Medicinal Benefits

Novarapid Penfil 100 mg Injection works by ensuring rapid and consistent sugar control. Novarapid Penfil 100 mg Injection is a fast-acting form of insulin that helps lower blood sugar levels after the intake of food. It prevents the risk of having severe complications of diabetes. It stimulates the recovery of sugar in muscle and fat cells and thus suppresses sugar production in the liver. Novarapid Penfil 100 mg Injection helps in improving the glycaemic control, which in turn decreases the risk of progression of complications of diabetes like damage to the retina (retinopathy), damage to the kidney (nephropathy), impairment of nerve cells (neuropathy), delayed wound healing, diabetic foot ulcer and others. Besides this, Novarapid Penfil 100 mg Injection can be safely prescribed to the diabetic mother during pregnancy and lactation.

How Novarapid Penfil 100 mg Injection Works

Novarapid Penfil 100 mg Injection works by ensuring rapid and consistent sugar control. Novarapid Penfil 100 mg Injection is a fast-acting form of insulin that helps lower blood sugar levels after food intake. It prevents the risk of having severe complications of diabetes. It stimulates the recovery of sugar in muscle and fat cells and thus suppresses sugar production in the liver.

Side Effects of Novarapid Penfil 100 mg Injection

  • Hypokalaemia (low potassium)
  • Hypoglycaemia (low blood sugar level)
  • Local injection site reactions
  • Lipodystrophy (fat deposition under the skin)
  • Rash
  • Pruritus (itchy skin)

What if I have taken an overdose of Novarapid Penfil 100 mg Injection

Do not take more than the prescribed dose of Novarapid Penfil 100 mg Injection as it may cause overdose and lead to low blood sugar. If you suspect you have taken overdose or have symptoms of low blood sugar or other symptoms such as seizures (fits) or loss of consciousness, please consult a doctor immediately.

Drug Warnings

Novarapid Penfil 100 mg Injection is for subcutaneous (under the skin) use only and should never be administered intravenously (IV) or in the veins. If you are changing the brand of insulin or if you need to inject your insulin by another method, it should be done under strict medical supervision. Cases of heart failure were reported when pioglitazone was used with insulin, especially in patients at high risk of cardiac heart failure. The first symptoms of hyperglycaemia (high blood sugar level) may include symptoms like excessive thirst, dry mouth, increased frequency of urination, nausea, vomiting, drowsiness, flushed dry skin, loss of appetite and acetone odour of the breath. You should closely monitor these symptoms. Symptoms like heart failure, weight gain and oedema (fluid deposition in tissue) should not be overruled. It is advisable not to consume alcohol as it may either increase or decrease your blood glucose level. Care should be taken while travelling across more than two time zones. Your doctor may adjust your insulin schedule. Novarapid Penfil 100 mg Injection may decrease the level of potassium, leading to a state of hypokalaemia that, if left untreated, may lead to respiratory paralysis, irregular heartbeat rhythm, coma and even death. Do not take Novarapid Penfil 100 mg Injection if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs.

Drug-Drug Interactions

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Insulin aspartCiprofloxacin
Severe
Insulin aspartGrepafloxacin
Severe

Drug-Drug Interactions

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Insulin aspartCiprofloxacin
Severe
How does the drug interact with Novarapid Penfil 100 mg Injection 1's:
Taking Novarapid Penfil 100 mg Injection 1's with ciprofloxacin affects blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia(low blood glucose).

How to manage the interaction:
Although taking ciprofloxacin and Novarapid Penfil 100 mg Injection 1's together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult a doctor if you experience headaches, dizziness, sleepiness, anxiety, disorientation, tremors, nausea, hunger, weakness, increased sweat, and a rapid heartbeat, increased hunger, thirst, and urine. It is recommended to maintain blood glucose levels.
Insulin aspartGrepafloxacin
Severe
How does the drug interact with Novarapid Penfil 100 mg Injection 1's:
Taking Novarapid Penfil 100 mg Injection 1's with Grepafloxacin affects blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia have been reported.

How to manage the interaction:
There could be a possible interaction between Novarapid Penfil 100 mg Injection 1's and grepafloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
Insulin aspartTrovafloxacin
Severe
How does the drug interact with Novarapid Penfil 100 mg Injection 1's:
Taking Novarapid Penfil 100 mg Injection 1's with Trovafloxacin affects blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia have been reported.

How to manage the interaction:
There could be a possible interaction between Novarapid Penfil 100 mg Injection 1's and Trovafloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms of hypoglycemia, which include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat, or symptoms of hyperglycemia which may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
Insulin aspartCarvedilol
Severe
How does the drug interact with Novarapid Penfil 100 mg Injection 1's:
Taking Novarapid Penfil 100 mg Injection 1's with carvedilol may increase the therapeutic efficacy of carvedilol.

How to manage the interaction:
There could be a possible interaction between Novarapid Penfil 100 mg Injection 1's and carvedilol but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience any unusual symptoms like shaking, palpitations, rapid heartbeat. Do not stop any medications without consulting a doctor.
Insulin aspartLevofloxacin
Severe
How does the drug interact with Novarapid Penfil 100 mg Injection 1's:
Taking Novarapid Penfil 100 mg Injection 1's with levofloxacin affects blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia(low blood glucose).

How to manage the interaction:
There could be a possible interaction between Novarapid Penfil 100 mg Injection 1's and Levofloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms of hypoglycemia, which include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat, or symptoms of hyperglycemia which may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.
Insulin aspartEnoxacin
Severe
How does the drug interact with Novarapid Penfil 100 mg Injection 1's:
Taking Novarapid Penfil 100 mg Injection 1's with Enoxacin affects blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia have been reported.

How to manage the interaction:
There could be a possible interaction between Novarapid Penfil 100 mg Injection 1's and enoxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms of hypoglycemia, which include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat, or symptoms of hyperglycemia which may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
Insulin aspartNorfloxacin
Severe
How does the drug interact with Novarapid Penfil 100 mg Injection 1's:
Taking Novarapid Penfil 100 mg Injection 1's with norfloxacin affects blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia have been reported.

How to manage the interaction:
There could be a possible interaction between Novarapid Penfil 100 mg Injection 1's and norfloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as headache, dizziness, drowsiness, nervousness, confusion, tremors, nausea, hunger, weakness, sweating, palpitation, rapid heartbeat, increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.
Insulin aspartCinoxacin
Severe
How does the drug interact with Novarapid Penfil 100 mg Injection 1's:
Taking Novarapid Penfil 100 mg Injection 1's with cinoxacin affects blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia(low blood glucose).

How to manage the interaction:
Although there is a interaction between Novarapid Penfil 100 mg Injection 1's and Cinoxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms of hypoglycemia, which include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat, symptoms of hyperglycemia, which include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
Insulin aspartGatifloxacin
Severe
How does the drug interact with Novarapid Penfil 100 mg Injection 1's:
Taking Novarapid Penfil 100 mg Injection 1's with Gatifloxacin affects blood glucose levels, hyperglycemia (high blood glucose) and, less frequently, hypoglycemia.

How to manage the interaction:
There could be a possible interaction between Novarapid Penfil 100 mg Injection 1's and gatifloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms of hypoglycemia which include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat, or symptoms of hyperglycemia which may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to a doctor.
Insulin aspartGemifloxacin
Severe
How does the drug interact with Novarapid Penfil 100 mg Injection 1's:
Taking Novarapid Penfil 100 mg Injection 1's with Gemifloxacin affects blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia have been reported.

How to manage the interaction:
There could be a possible interaction between Novarapid Penfil 100 mg Injection 1's and Gemifloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms of hypoglycemia, which include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat, or symptoms of hyperglycemia which may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercise may lower your body’s need for insulin during and sometimes after physical activity.
  • Exercise may also speed up the effect of an insulin dose, especially if the exercise involves the area of the injection site (for example, the leg should not be used for injection just before running).
  • Discuss with your doctor how to adjust your insulin regimen to accommodate exercise. 
  • Avoid eating sugar food and prefer food cooked food low in calories.
  • When travelling across more than two time zones, you should consult your doctor about making adjustments to your insulin schedule.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Novarapid Penfil 100 mg Injection Substitute

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Alcohol

Unsafe

You are recommended not to consume alcohol along with Novarapid Penfil 100 mg Injection to avoid unpleasant side-effects. Alcohol may either decrease or increase the blood sugar level which can be fatal.

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Pregnancy

Safe if prescribed

Novarapid Penfil 100 mg Injection can be used during pregnancy. Your insulin dose may need to be changed during pregnancy and after delivery.

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Breast Feeding

Safe if prescribed

Novarapid Penfil 100 mg Injection can be given safely to nursing mothers but only under the supervision of a physician.

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Driving

Unsafe

Drive with caution, Novarapid Penfil 100 mg Injection usually causes drowsiness and affects driving ability. Your ability to concentrate and react may be reduced if you have hypoglycaemia (low blood sugar).

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Liver

Caution

Novarapid Penfil 100 mg Injection to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Novarapid Penfil 100 mg Injection to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Novarapid Penfil 100 mg Injection can be given safely to children provided; dose has to be prescribed by a child specialist.

FAQs

Novarapid Penfil 100 mg Injection is used to treat diabetes mellitus. It works by ensuring rapid and consistent sugar control.
Novarapid Penfil 100 mg Injection works by replacing the insulin that is normally produced by the body. It helps move sugar from the blood into other body tissues where it is used for energy. Novarapid Penfil 100 mg Injection also prevents the liver from producing more sugar.
Novarapid Penfil 100 mg Injection typically begins working after 10-20 minutes, and will last for between 3 and 5 hours.
Cold sweat; cool pale skin; headache; rapid heartbeat; feeling sick; feeling very hungry; temporary vision changes; drowsiness; unusual tiredness and weakness; nervousness or tremor; feeling anxious; feeling confused; difficulty in concentrating are some of the common signs of the low blood sugar level in an individual.
If you experience low blood sugar, eat glucose tablets or another high sugar snack (e.g. sweets, biscuits, fruit juice). Measure your blood sugar if possible and rest. Always carry glucose tablets or high sugar snacks with you. You should give a call to any of your family members if you are feeling dizziness or drowsiness.
Local allergic reactions (pain, redness, hives, inflammation, bruising, swelling and itching) at the injection site may occur. These usually disappear after a few weeks of taking your insulin. If they do not disappear, or if they spread throughout your body, talk to your doctor immediately.
Novarapid Penfil 100 mg Injection can be given to treat both the condition of type 1 and type 2 diabetes mellitus. However, your doctor will decide whether Novarapid Penfil 100 mg Injection can be given to you or not depending on your present condition. Novarapid Penfil 100 mg Injection should be avoided in patients who are allergic to Novarapid Penfil 100 mg Injection or other forms of insulin, patients with kidney disease, liver disease, low blood sugar/glucose level (hypoglycaemia), and low potassium level (hypokalaemia).
Cut back on foods high in sodium, alcohol, fried foods, and high-carb food and drinks like sugary drinks, drinks with added sugar, white rice and starchy vegetables.
Novarapid Penfil 100 mg Injection should not be discontinued without a doctor's consultation as stopping Novarapid Penfil 100 mg Injection may cause severe hypoglycaemia (low blood sugar) and ketoacidosis (buildup of acid in the blood). Consult the doctor if you feel uncomfortable after taking Novarapid Penfil 100 mg Injection.
The injection site should be changed to prevent skin changes like lumps under the skin. Novarapid Penfil 100 mg Injection may not work well if injected into the lumpy area.
Maintain a healthy diet and exercise regularly. Limit sugar intake and avoid smoking & alcohol consumption. Manage stress by doing meditation or yoga.
Hypoglycaemia (low blood sugar) may occur because you inject too much insulin, miss or delay meals, do not eat enough, eat food containing less carbohydrate than normal, drink alcohol, lose carbohydrates due to vomiting or diarrhoea, do more exercise than usual or a different type of physical activity, are recovering from an injury, illness, operation or stress, or are taking/have stopped taking other medicines.
Check the label for directions and use Novarapid Penfil 100 mg Injection as advised by the doctor. Talk to the doctor if you have any concerns. Novarapid Penfil 100 mg Injection should be taken immediately before a meal. Eat a meal or snack within 10 minutes of the injection to avoid low blood sugar. When necessary, Novarapid Penfil 100 mg Injection can be given soon after a meal.
Novarapid Penfil 100 mg Injection belongs to the class of medicines called insulin analogues used to improve glycaemic control.
Novarapid Penfil 100 mg Injection contains Insulin aspart which is produced in a genetically modified strain of Saccharomyces cerevisiae (baker's yeast) using rDNA technology.
Novarapid Penfil 100 mg Injection may cause weight gain due to a decrease in glucosuria (excretion of glucose through urine). Consult the doctor if you have any concerns.
Novarapid Penfil 100 mg Injection may be needed for the rest of your life if you have type 1 diabetes as your body is not able to produce sufficient insulin. However, if you have type 2 diabetes your doctor might prescribe Novarapid Penfil 100 mg Injection for a short duration based on your condition.
Yes, Novarapid Penfil 100 mg Injection may cause hypoglycaemia (low blood glucose levels). Regularly monitor blood sugar levels and take a source of sugar such as glucose biscuits, candy or fruit juices if you experience symptoms of hypoglycaemia cold sweat, headache, rapid heartbeat, feeling sick, drowsiness, unusual tiredness, and weakness.
Yes, Novarapid Penfil 100 mg Injection is a fast-acting insulin. It helps control immediate post-meal high blood glucose levels. You should eat a meal within 5-10 minutes after taking a dose of Novarapid Penfil 100 mg Injection.
Novarapid Penfil 100 mg Injection is safe to be used in pregnancy if prescribed by the doctor. Careful monitoring of blood sugar levels is advised.

Country of origin

India

Manufacturer/Marketer address

16Th Floor, Godrej Bkc, Plot €“ C, €Œg” Block, Bandra-Kurla Complex, Bandra (East), Mumbai €“ 400 051, India
Other Info - NOV0066

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Keep Refrigerated. Do not freeze.

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