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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Norpace Capsule is used to treat irregular heartbeat. It contains disopyramide which helps correct irregular heartbeats by blocking certain electrical signals in the heart. In some cases, this medicine may cause side effects such as blurred or double vision, stomach pain, little or no urinating, and low blood sugar. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

DISOPYRAMIDE-100MG

Manufacturer/Marketer :

RPG Life Sciences Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Norpace Capsule

Norpace Capsule belongs to a group of medicines called anti-arrhythmic agents used to treat irregular heartbeats. An irregular heartbeat is a condition in which your heart beats irregularly, too fast, or too slow. Norpace Capsule helps slow the heart rate and prevent arrhythmias (abnormal heart rhythms).  

Norpace Capsule contains disopyramide, i.e., anti-arrhythmic agents. It helps to correct irregular heartbeats to a normal rhythm by blocking certain electrical signals in the heart. An irregular heartbeat treatment reduces the risk of blood clots, heart attack, or stroke.

Norpace Capsule should be taken as prescribed by the doctor. Your doctor might conduct ECGs and blood pressure monitoring during the treatment to monitor your dose. Some people may experience common side effects like blurred or double vision, stomach pain, little or no urinating, and low blood sugar. Most of these side effects of Norpace Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are known to be allergic to Norpace Capsule or any other medicines, please tell your doctor. Norpace Capsule is not recommended for use in children. Pregnant or breastfeeding women are advised to consult a doctor before taking Norpace Capsule . Inform your doctor before taking Norpace Capsule if you have kidney or liver disease, enlarged prostate, glaucoma (increased eye pressure), or low potassium levels in the blood (hypokalaemia). Do not take Norpace Capsule if you are already on other medications to regulate your heartbeat. Do not drive or operate machinery as Norpace Capsule might cause blurred vision, dizziness, and low blood pressure. Take Norpace Capsule with caution if you are elderly (age above 65), have low body weight, or have kidney or liver problems.

Uses of Norpace Capsule

Treatment of Irregular heartbeats (Arrhythmias)

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Norpace Capsule is an anti-arrhythmic agent that is used to treat irregular heartbeats. Norpace Capsule works by blocking certain electrical signals in the heart, which cause an irregular heartbeat. Thus, it slows down the rate at which the heart beats and makes the heart rate normal. Norpace Capsule improves heart failure symptoms such as exercise capacity and reduces the number of hospitalizations.

How Norpace Capsule Works

Norpace Capsule contains disopyramide, i.e., anti-arrhythmic agents. It helps to correct irregular heartbeats to a normal rhythm by blocking certain electrical signals in the heart. An irregular heartbeat treatment reduces the risk of blood clots, heart attack, or stroke.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Norpace Capsule

  • Low blood sugar
  • Dry mouth
  • Nausea
  • Headache
  • Constipation
  • Muscle weakness
  • Blurred vision
  • Muscle pain or weakness.
  • Difficult urination
  • Dry eyes, nose, and throat
  • Urinary retention
  • Frequent urination
  • Bloating and gas pains
  • Dizziness
  • Fatigue

What if I have taken an overdose of Norpace Capsule

Take Norpace Capsule only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include slow or irregular heartbeat, dry mouth, difficulty urinating, constipation, and loss of consciousness. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Pregnant women are advised to consult a doctor before taking Norpace Capsule . Do not take Norpace Capsule if you are a breast-feeding woman. If you are known to be allergic to Norpace Capsule or any other medicines, please tell your doctor. Avoid intake of alcohol with Norpace Capsule as it may increase the risk of drowsiness. Norpace Capsule may cause vision problems in some people. Make sure you are not affected before driving. Take Norpace Capsule with caution if you have kidney or liver disease, enlarged prostate, heart disease, or low blood sugar levels. Before taking Norpace Capsule , inform your doctor if you are already taking medicines such as antibiotics and antifungal medicines, an anti-malarial (halofantrine), laxatives to treat constipation, anticoagulants, e.g., warfarin, a medicine used to treat glaucoma (acetazolamide), antivirals, e.g., ritonavir, saquinavir. Speak to your doctor immediately if you have an allergic reaction, palpitations, or an uneven fast or slow heartbeat.

Drug-Drug Interactions

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DisopyramideDronedarone
Critical
DisopyramideKetoconazole
Critical

Drug-Drug Interactions

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DisopyramideDronedarone
Critical
How does the drug interact with Norpace Capsule 10's:
Taking Norpace Capsule 10's with Dronedarone can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Norpace Capsule 10's with Dronedarone is not recommended, as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, diarrhea or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DisopyramideKetoconazole
Critical
How does the drug interact with Norpace Capsule 10's:
Taking Ketoconazole and Norpace Capsule 10's together can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Ketoconazole with Norpace Capsule 10's is not recommended as it can cause an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms like dizziness, irritation, confusion, chest pain or tightness, swelling, fatigue, palpitations, shortness of breath, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
DisopyramideCisapride
Critical
How does the drug interact with Norpace Capsule 10's:
Combining Norpace Capsule 10's with Cisapride can increase the risk an irregular heart rhythm .

How to manage the interaction:
Taking Norpace Capsule 10's with Cisapride is not recommended, as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, diarrhea or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
DisopyramidePotassium chloride
Critical
How does the drug interact with Norpace Capsule 10's:
Taking Norpace Capsule 10's and Potassium chloride together can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Potassium chloride and Norpace Capsule 10's is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
DisopyramideGatifloxacin
Critical
How does the drug interact with Norpace Capsule 10's:
Taking Gatifloxacin and Norpace Capsule 10's can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Gatifloxacin and Norpace Capsule 10's together is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
DisopyramideMoxifloxacin
Critical
How does the drug interact with Norpace Capsule 10's:
Using Norpace Capsule 10's together with Moxifloxacin can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Moxifloxacin with Norpace Capsule 10's is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting your doctor.
DisopyramideZiprasidone
Critical
How does the drug interact with Norpace Capsule 10's:
Coadministration of Norpace Capsule 10's with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Norpace Capsule 10's with Ziprasidone is not recommended, as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, diarrhea or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
DisopyramideItraconazole
Critical
How does the drug interact with Norpace Capsule 10's:
Coadministration of Itraconazole with Norpace Capsule 10's can reduce the metabolism and increase the levels of Norpace Capsule 10's in the body. This may increase the risk or severity of side effects like irregular heart rhythms.

How to manage the interaction:
Taking Itraconazole with Norpace Capsule 10's together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of headaches, dizziness, irritation, confusion, chest pain or tightness, swelling, fatigue, palpitations, shortness of breath, or constipation, you should contact your doctor immediately. Do not stop using any medications without talking to your doctor.
DisopyramidePotassium citrate
Critical
How does the drug interact with Norpace Capsule 10's:
Taking Norpace Capsule 10's and Potassium citrate together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Although taking Norpace Capsule 10's and Potassium citrate together is not recommended as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
DisopyramideOfloxacin
Critical
How does the drug interact with Norpace Capsule 10's:
Coadministration of Ofloxacin with Norpace Capsule 10's can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Ofloxacin with Norpace Capsule 10's together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a low-salt diet and minimize eating processed foods as they contain more sodium.

  • Regular exercise lowers blood pressure and keeps blood vessels and the heart in good condition.

  • Quit smoking as smoking increases blood pressure and heart rate.

  • Eat a balanced and healthy diet with plenty of vegetables, fruits, and low-fat or fat-free products.

Habit Forming

No

Therapeutic Class

ANTIARRHYTHMICS

Norpace Capsule Substitute

Substitutes safety advice
  • Norpace New Capsule 10's

    29.93per tablet
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption with Norpace Capsule as it may increase drowsiness and reduce the amount of Norpace Capsule in the blood leading to abnormal heart function.

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Pregnancy

Caution

Norpace Capsule should not be taken until prescribed. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Caution

Norpace Capsule should not be taken until prescribed. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Driving

Unsafe

Norpace Capsule may cause dizziness and blurred vision in some people. So, make sure you are not affected before driving or operating machinery.

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Liver

Caution

Take Norpace Capsule with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Norpace Capsule with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Norpace Capsule is not recommended for use in children.

FAQs

Norpace Capsule is used to treat arrhythmia (irregular heartbeats). It helps slow the heart rate and prevent abnormal heart rhythms.
Norpace Capsule contains disopyramide that works by blocking abnormal electrical signals in the heart. Thus Norpace Capsule helps to treat uneven heartbeats and helps in normalizing the heart rhythm.
No, you are not recommended to take amiodarone with Norpace Capsule as co-administration of these two medicines may increase the levels of Norpace Capsule in the blood resulting in Norpace Capsule toxicity. However, please consult a doctor before taking other medicines with Norpace Capsule to adjust the dose appropriately.
Do not stop using Norpace Capsule even if you feel better. It should be strictly used as advised by your doctor to avoid recurring symptoms like irregular heartbeat and to worsen the disease.
Norpace Capsule should be used with caution in cases of any allergic reactions, heart problems like heart failure, slow heartbeat, QT prolongation (heart muscle takes longer than usual to recharge between beats) in the ECG (electrocardiogram), and electrolyte imbalance (low levels of potassium and magnesium).
Store Norpace Capsule away from direct sunlight and at a temperature not exceeding 30°C. Keep this medicine out of sight and reach of children.
If you missed a dose, take Norpace Capsule as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.
Yes, Norpace Capsule may cause dry mouth as a temporary side effect in some people. It is not necessary for everyone taking Norpace Capsule to experience this side effect. However, to avoid such side effects, drink plenty of water, regularly rinse your mouth, practice good oral hygiene and suck on sugarless candy. However, if the condition persists or worsens, please consult a doctor.

Country of origin

India

Manufacturer/Marketer address

463, 4 th Floor, RPG HOUSE, Dr. Annie Besant Road, Worli, Mumbai – 400 030. Maharashtra, INDIA
Other Info - NOR0078

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