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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 10, 2024 | 7:18 PM IST
Normatone Syrup is used to stimulate the appetite and treat alimentary tract and metabolism problems. It helps treat lack of appetite, weight loss, and anorexia nervosa (an eating disorder with low body weight). It enhances food consumption and hence helps in fulfilling nutritional needs. It may cause side effects such as dryness in the mouth, constipation, sleepiness, drowsiness, and blurred vision. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Mankind Pharma Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Normatone Syrup

Normatone Syrup belongs to a group of combination medicines called 'appetite enhancers' used to stimulate the appetite and treat alimentary tract and metabolism problems. Normatone Syrup helps treat lack of appetite, weight loss, and anorexia nervosa (an eating disorder with low body weight). Lack of appetite results in missing meals. This, in turn, may cause a lack of some essential and nonessential nutrients. Taking Normatone Syrup enhances food consumption and hence helps in fulfilling nutritional needs.

Normatone Syrup combines three medicines: cyproheptadine, sorbitol, and tricholine. Cyproheptadine is an appetite enhancer. It works by decreasing the effect of a chemical messenger (serotonin) in the hypothalamus, a portion of the brain which controls appetite. Sorbitol behaves as a syrup base and an osmotic laxative to reduce constipation. On the other hand, Tricholine is a bile acid-binding agent that eliminates bile acids from the body. The liver then generates more bile acids using cholesterol, due to which cholesterol level is reduced.

Take Normatone Syrup as prescribed by your doctor. Depending on your medical conditions, you are advised to take Normatone Syrup for as long as your doctor has prescribed it for you. You may experience dryness in the mouth, constipation, sleepiness, drowsiness, and blurred vision. Most of these side effects of Normatone Syrup do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Inform your doctor before taking Normatone Syrup if you have asthma, hyperthyroidism, high blood pressure, intraocular (eye) pressure, or heart problems. Consult your doctor before taking Normatone Syrup if you are pregnant. It is not recommended to take Normatone Syrup if you are breastfeeding. Normatone Syrup may cause drowsiness, so drive with caution. Avoid consumption of alcohol while taking Normatone Syrup as it may cause increased drowsiness. Keep your doctor informed about all the medicines and your health condition to rule out any side effects.

Uses of Normatone Syrup

Treatment of Loss of appetite (anorexia).

Medicinal Benefits

Normatone Syrup belongs to a group of medicines called Appetite enhancers used to stimulate the appetite and increase body metabolism. Normatone Syrup is indicated for loss of appetite, weight loss, and anorexia nervosa (an eating disorder with low body weight). Normatone Syrup is also prescribed for underweight children with inadequate dietary intake, loss of appetite, anaemia, liver, or digestive disorder. Additionally, Normatone Syrup is used as an adjunct to anti-tubercular (anti-TB) and antiretroviral treatment (anti-HIV) for weight gain. Normatone Syrup helps stimulate appetite, ensures weight gain, provides effective hepatoprotective action, and enhances protein synthesis. It is also indicated in hepatobiliary disorder (liver disease) associated with anorexia (lack/loss of appetite).

Directions for Use

Oral Suspension/syrup: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Normatone Syrup

  • Vomiting

  • Nausea

  • Weakness

  • Dryness in mouth

  • Constipation

  • Black or Tarry stools

  • Sleepiness

  • Drowsiness

  • Blurred vision

Drug Warnings

Do not take Normatone Syrup if you are allergic to any of its contents; you have nausea, vomiting, stomach pain, glaucoma, peptic ulcers, prostatic hypertrophy, bladder neck obstruction, or pyloroduodenal obstruction. Inform your doctor before taking Normatone Syrup if you have asthma, hyperthyroidism, high blood pressure, intraocular (eye) pressure or heart problems. Normatone Syrup may show additive effects if taken along with alcohol, CNS depressants, and anti-anxiety drugs. Consult your doctor before taking Normatone Syrup if you are pregnant. It is not recommended to take Normatone Syrup if you are breastfeeding. Normatone Syrup may cause drowsiness, so drive with caution. Avoid consumption of alcohol while taking Normatone Syrup as it may cause increased drowsiness.

Drug Interactions

Drug-Drug Interactions: Normatone Syrup may have interaction with an antihistamine (diphenhydramine, cetirizine), an antidepressant (duloxetine, fluoxetine, sertraline), anti-convulsant (pregabalin, topiramate), and anti-psychotic (quetiapine), medicine for hepatitis B infection (lamivudine).

Food-Drug Interactions: No interactions found/established.

Drug-Disease Interactions: Normatone Syrup may have interactions with asthma, intestine problems, diabetes, heart, kidney, and liver problems.

Drug-Drug Interactions Checker List

  • DIPHENHYDRAMINE
  • CETIRIZINE
  • DULOXETINE
  • FLUOXETINE
  • SERTRALINE
  • PREGABALIN
  • TOPIRAMATE
  • QUETIAPINE
  • LAMIVUDINE

Habit Forming

No

Diet & Lifestyle Advise

  • Exercise regularly as it helps increase your energy expenditure, thereby helping in increasing hunger.

  • You may eat more if you are having a good time during your meal. So, try to make mealtimes enjoyable by eating with friends and family or watching a favourite show.

  • Change your menu and eat food that you enjoy.

  • Try not to skip meals. Make time for eating. 

  • If you feel eating three times as overwhelming, eat six smaller meals.

  • Include calorie-containing beverages in your diet, such as protein shakes, fruit juices, milk, etc.

  • Proper management of basic hygiene and bowel regularity can positively affect appetite in adults.

  • Setting the alarm for mealtime or posting a meal schedule on the wall could help adults remind them to eat.

  • Limit excessive snacking in between mealtimes.

  • If you have trouble obtaining or preparing food or having difficulty with limited food choices, try delivery services that deliver fully equipped healthy meals.

Special Advise

  • Tricholine present in Normatone Syrup is a Pregnancy category risk D medicine, so its use in pregnant women is not recommended. 

  • Cyproheptadine present in Normatone Syrup may cause dizziness and blur your vision, so do not drive a vehicle, operate heavy machinery, or perform hazardous tasks.

Disease/Condition Glossary

Appetite loss: Appetite loss is a condition in which an individual has no desire to eat food. Lack of appetite causes missing meals or less urge of hungriness, resulting in a deficiency of essential and non-essential nutrients required for the proper metabolism and growth of our body. The most common reasons for the decrease in appetite include psychological conditions like stress, anxiety, depression, gastrointestinal disorders (such as acidity, peptic ulcers, and ulcerative colitis), slow metabolism, age, lowered activity levels, other disease conditions (like AIDS, HIV, cancer) and some medication side effects. Some drugs, like digoxin, fluoxetine, quinidine, and hydralazine, can cause loss of appetite (anorexia).

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Normatone Syrup as it may cause increased drowsiness.

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Pregnancy

Unsafe

Tricholine present in Normatone Syrup is a pregnancy category risk D medicine, so its use in pregnant women is not recommended.

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Breast Feeding

Unsafe

Taking Normatone Syrup if you are breastfeeding is not recommended because Normatone Syrup contains cyproheptadine, which may cause less breast milk production.

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Driving

Caution

Normatone Syrup may cause drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor before taking Normatone Syrup if you have a liver impairment or any concerns.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Normatone Syrup if you have kidney impairment or any concerns.

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Children

Safe if prescribed

Normatone Syrup is safe for children above 1year if prescribed by the doctor.

Country of origin

INDIA

Manufacturer/Marketer address

Sarkhej-Dholka Road, Bhat, Ahmedabad-382 210, INDIA.
Other Info - NOR0145

Author Details

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FAQs

Normatone Syrup is used for the treatment of Loss of appetite (anorexia).
Yes, using Normatone Syrup can cause dizziness (feeling faint, weak, shaky, or lightheaded) in some patients. If you feel dizzy or faint, it is better to rest and continue once you feel better. Do not drive or use any machines that require alertness.
Normatone Syrup can be given to children if prescribed by the doctor. The dose may vary depending on the child’s age. Normatone Syrup is prescribed for underweight children with inadequate dietary intake, loss of appetite, anaemia, liver, or digestive disorder.
Antidepressants, along with Normatone Syrup , especially monoamine oxidase inhibitors (MAOIs), may prolong and increase the effects of Normatone Syrup . Consult your doctor before taking Normatone Syrup with other medicines to avoid unpleasant side effects.
Normatone Syrup causes weight gain by stimulating the appetite. Normatone Syrup helps in weight gain and growth.
Dry mouth could be a side-effect of Normatone Syrup . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent mouth drying.
You may experience dryness in the mouth, constipation, sleepiness, drowsiness, and blurred vision. Most of these side effects of Normatone Syrup do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
No, Normatone Syrup is not a blood tonic. It is primarily used as an appetite stimulant and treat alimentary tract and metabolism problems.
No, Normatone Syrup is not habit-forming. However, use it as prescribed by your doctor to avoid any potential side effects.
Normatone Syrup is not recommended for children under 1 year of age. Please consult your doctor before giving Normatone Syrup to your child to ensure safety and proper dosage.
Normatone Syrup should be used with caution in elderly people as they are at increased risk of getting side effects. Normatone Syrup should be used only if is prescribed by a doctor.
Normatone Syrup is a combination of three medications, cyproheptadine, sorbitol, and tricholine. Cyproheptadine enhances appetite by decreasing the effect of serotonin in the hypothalamus, a portion of the brain which controls appetite. Sorbitol reduces constipation, and tricholine eliminates bile acids from the body, reducing cholesterol levels.
Take Normatone Syrup as prescribed by your doctor. It is usually taken before meals to help stimulate appetite. It's important to follow your doctor's instructions regarding the dosage and timing to ensure the best results.
Normatone Syrup should be stored in a dry place at room temperature. Protect from light. Keep it out of reach and sight of children and pets.
No, it is not recommended for children below 1 year, individuals who are allergic to Normatone Syrup and pregnant or breastfeeding women. Also, inform your doctor if you are taking any other medicines.
If you suspect you have taken an overdose of Normatone Syrup , consult your doctor immediately as it may cause severe symptoms.

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