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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
NOBEL MR 2MG TABLET is used to relieve pain due to muscle spasms, headaches, migraine, rheumatic pain, backache, and period pain. It works by blocking the chemical messengers that cause pain and relieving muscle spasms. In some cases, this medicine may cause side effects such as nausea, vomiting, dizziness, dry mouth, and diarrhoea. Let the doctor know if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About NOBEL MR 2MG TABLET

NOBEL MR 2MG TABLET is a combination medicine used to relieve pain due to muscle spasms such as arthritis, muscle pain, tooth pain, bone and joint pain, headache, and period pain. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable.
 
NOBEL MR 2MG TABLET contains Nimesulide (analgesic), Paracetamol (mild analgesic and fever reducer), and Tizanidine (muscle relaxant). Nimesulide and Paracetamol work by blocking the effect of chemical messengers that cause pain and inflammation at the injured or damaged site. Tizanidine works on the centres of the spinal cord and brain, which helps relieve muscle stiffness, thereby improving muscle movements. Together, NOBEL MR 2MG TABLET helps in reducing pain due to muscle spasms.
 
You are advised to take NOBEL MR 2MG TABLET for as long as your doctor has prescribed it for you depending on your medical condition. You may experience certain common side-effects such as nausea, vomiting, dizziness, dry mouth, and diarrhoea in some cases. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. NOBEL MR 2MG TABLET may cause dizziness, so drive with caution. NOBEL MR 2MG TABLET should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol with NOBEL MR 2MG TABLET as it could lead to increased dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects. 

Uses of NOBEL MR 2MG TABLET

Treatment of Musculoskeletal pain, Muscle spasms, Arthritis.

Directions for Use

Swallow NOBEL MR 2MG TABLET as a whole with a glass of water, do not chew, or break it.

Medicinal Benefits

NOBEL MR 2MG TABLET is a combination of three drugs, namely: Tizanidine, Nimesulide, and Paracetamol. NOBEL MR 2MG TABLET is a combination medicine used to relieve pain and inflammation associated with osteoarthritis,  muscle pain, tooth pain, bone and joint pain, headache, and period pain. Tizanidine is a muscle relaxant that works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. Nimesulide and Paracetamol are analgesics that work by blocking the effect of chemical messengers that cause pain and inflammation at the injured or damaged site. Together, NOBEL MR 2MG TABLET helps in relieving pain due to muscle spasms. 

How NOBEL MR 2MG TABLET Works

NOBEL MR 2MG TABLET contains Nimesulide (analgesic), Paracetamol (mild analgesic and fever reducer), and Tizanidine (muscle relaxant). Nimesulide and Paracetamol work by blocking the effect of chemical messengers that cause pain and inflammation at the injured or damaged site. Tizanidine works on the centres of the spinal cord and brain, which helps relieve muscle stiffness, thereby improving muscle movements. Together, NOBEL MR 2MG TABLET helps in reducing pain due to muscle spasms.

Storage

Store in a cool and dry place away from sunlight

Side Effects of NOBEL MR 2MG TABLET

  • Nausea
  • Vomiting
  • Dizziness
  • Diarrhoea
  • Dry mouth
  • Loss of appetite
  • Indigestion

What if I have taken an overdose of NOBEL MR 2MG TABLET

Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take NOBEL MR 2MG TABLET if you are allergic to any of its contents, if you have/had severe heart problems, stomach ulcer or perforation, and bleeding problems such as bleeding from the stomach, intestine, or brain, bypass surgery, heart attack, blood circulation problems, or inflammation of intestines. Inform your doctor if you have high blood pressure, heart problems, high cholesterol, diabetes, asthma, inflammatory bowel disease, liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. NOBEL MR 2MG TABLET may cause dizziness, so drive only if you are alert. NOBEL MR 2MG TABLET is not recommended for children as safety and effectiveness have not been established. Stop taking NOBEL MR 2MG TABLET and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other analgesic for pain relief along with NOBEL MR 2MG TABLET unless prescribed.  

Drug-Drug Interactions

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TizanidineFluvoxamine
Critical
TizanidineZiprasidone
Critical

Drug-Drug Interactions

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TizanidineFluvoxamine
Critical
How does the drug interact with NOBEL MR 2MG TABLET:
Taking Fluvoxamine with NOBEL MR 2MG TABLET it can increases the risk of side effects.

How to manage the interaction:
Although Fluvoxamine with NOBEL MR 2MG TABLET is not recommended, but can be taken together if prescribed by a doctor. However, if you experience drowsiness, dizziness, low blood pressure, slurred speech, confusion, or severe weakness, contact your doctor immediately. Do not stop using any medications without consulting a doctor.
TizanidineZiprasidone
Critical
How does the drug interact with NOBEL MR 2MG TABLET:
Co-administration of NOBEL MR 2MG TABLET with Ziprasidone can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking NOBEL MR 2MG TABLET with Ziprasidone is not recommended, as it can result in an interaction, but it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting. Do not discontinue any medications without consulting a doctor.
TizanidineDronedarone
Critical
How does the drug interact with NOBEL MR 2MG TABLET:
Coadministration of NOBEL MR 2MG TABLET with Dronedarone can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking NOBEL MR 2MG TABLET with Dronedarone is generally avoided as it can result in an interaction, it can be taken when prescribed by a doctor. If you experience sudden dizziness, shortness of breath, palpitations, or chest pain, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
TizanidineCiprofloxacin
Critical
How does the drug interact with NOBEL MR 2MG TABLET:
Coadministration of Ciprofloxacin and NOBEL MR 2MG TABLET together can increase the risk of side effects.

How to manage the interaction:
Using Ciprofloxacin and NOBEL MR 2MG TABLET together is avoided, as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience drowsiness, weakness, sweating, or palpitations contact the doctor immediately. Do not discontinue any medications without consulting the doctor.
TizanidineCisapride
Critical
How does the drug interact with NOBEL MR 2MG TABLET:
Coadministration of NOBEL MR 2MG TABLET with Cisapride can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking NOBEL MR 2MG TABLET with Cisapride is avoided as it can result in an interaction, it can be taken if your doctor has advised it. Contact your doctor immediately if you experience sudden dizziness, shortness of breath, palpitations, or vomiting. Do not discontinue any medications without consulting your doctor.
TizanidineSaquinavir
Critical
How does the drug interact with NOBEL MR 2MG TABLET:
Combining NOBEL MR 2MG TABLET with Saquinavir can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking NOBEL MR 2MG TABLET with Saquinavir is not recommended, as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhoea or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
TizanidineIrbesartan
Severe
How does the drug interact with NOBEL MR 2MG TABLET:
Combining NOBEL MR 2MG TABLET with Irbesartan can increase the risk of low blood pressure.

How to manage the interaction:
Taking Irbesartan with NOBEL MR 2MG TABLET together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any of these signs - headache, dizziness, feeling lightheaded, or fainting, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
TizanidineMexiletine
Severe
How does the drug interact with NOBEL MR 2MG TABLET:
Co-administration of NOBEL MR 2MG TABLET with mexiletine can increase the effect of NOBEL MR 2MG TABLET. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking NOBEL MR 2MG TABLET with Mexiletine can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as nausea, vomiting, diarrhoea, loss of appetite, headache, tremors, confusion, restlessness, insomnia, seizures, heart palpitations, and/or irregular heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TizanidineMetoprolol
Severe
How does the drug interact with NOBEL MR 2MG TABLET:
Coadministration of Metoprolol and NOBEL MR 2MG TABLET may reduce the efficiency of metoprolol.

How to manage the interaction:
Taking Metoprolol and NOBEL MR 2MG TABLET together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact your doctor immediately. do not discontinue any medications without talking to your doctor.
TizanidineLeflunomide
Severe
How does the drug interact with NOBEL MR 2MG TABLET:
Coadministration of NOBEL MR 2MG TABLET and leflunomide can increase the risk of liver problems.

How to manage the interaction:
Taking NOBEL MR 2MG TABLET and Leflunomide together can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes, instead, wear loose garments.
  • Rest well, and get plenty of sleep.
  • To avoid developing pressure sores, change your position every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

ANALGESICS

NOBEL MR 2MG TABLET Substitute

Substitutes safety advice
  • Sulid-MR Tablet

    4.05per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking NOBEL MR 2MG TABLET as it may cause increased drowsiness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks. NOBEL MR 2MG TABLET should not be taken during the last three months of pregnancy.

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Breast Feeding

Caution

Consult your doctor before taking NOBEL MR 2MG TABLET, your doctor will decide whether NOBEL MR 2MG TABLET can be taken by breastfeeding mothers or not.

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Driving

Caution

NOBEL MR 2MG TABLET may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

NOBEL MR 2MG TABLET should not be given to children as safety and effectiveness were not established.

FAQs

NOBEL MR 2MG TABLET is used to relieve pain due to muscle spasms such as arthritis, muscle pain, tooth pain, bone and joint pain, headache, and period pain.
NOBEL MR 2MG TABLET contains Nimesulide, Paracetamol, and Tizanidine. Nimesulide and Paracetamol work by blocking the effect of chemical messengers that cause pain and inflammation at the injured or damaged site. Tizanidine works on the centres of the spinal cord and brain, which helps relieve muscle stiffness, thereby improving muscle movements. Together, NOBEL MR 2MG TABLET helps in reducing pain due to muscle spasms.
NOBEL MR 2MG TABLET is used to reduce and relieve pain and inflammation associated with osteoarthritis. Arthritis is tenderness and swelling in the joints.
Diarrhoea might be a side-effect of NOBEL MR 2MG TABLET. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if the condition persists or worsens.
NOBEL MR 2MG TABLET should not be taken for longer durations unless prescribed by the doctor. Use the minimum effective dose for the shortest duration.
Dry mouth could be a side-effect of NOBEL MR 2MG TABLET. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevents drying of the mouth.
Taking NOBEL MR 2MG TABLET can elevate symptoms of gastric ulcer and bleeding. So, talk to your doctor before taking NOBEL MR 2MG TABLET if you have gastrointestinal bleeding or other bleeding problems like haemophilia before using NOBEL MR 2MG TABLET.

Country of origin

India

Manufacturer/Marketer address

208, Okhla Industrial Estate, Phase III, New Delhi - 110020
Other Info - NOB0020

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