Nixiclin-XL 0.25% Cream 50 gm belongs to a class of drugs called 'antifungal' primarily used to treat fungal nail infections. Fungal infection occurs when a fungus invades and affects the tissue on the skin.  Symptoms of a fungal infection include skin rash, irritation, redness, and scaling of the skin.  

Nixiclin-XL 0.25% Cream 50 gm contains 'Amorolfine' that works by stopping producing a chemical called 'ergosterol' in fungi that causes nail infection. Without ergosterol, the fungus cannot survive. As a result, infection-causing fungi die. 

Use Nixiclin-XL 0.25% Cream 50 gm as suggested by your doctor. Common side effects of Nixiclin-XL 0.25% Cream 50 gm may include dry skin, itching, redness, or burning sensation of the skin. Most of these side effects of Nixiclin-XL 0.25% Cream 50 gm do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are pregnant or a nursing mother, it is advised to consult a doctor before using Nixiclin-XL 0.25% Cream 50 gm. If you use Nixiclin-XL 0.25% Cream 50 gm in topical form, avoid smoking or going near naked flames as Nixiclin-XL 0.25% Cream 50 gm catches fire and burns easily. If you are using any steroidal cream, lotion or ointment, inform your doctor before taking Nixiclin-XL 0.25% Cream 50 gm to adjust the dose.

Nixiclin-XL 0.25% Cream 50 gm is an antifungal that is primarily used to treat fungal infections of nails and skin such as ringworm, jock itch and athlete’s foot, seborrheic dermatitis (dry, flaky skin on face, scalp, chest, upper back, or ears) and pityriasis (a type of skin rash that causes scaly, discoloured patches on chest, back, legs and arms). The fungal cell membranes are essential for their survival as they prevent unwanted substances into the cells and stop the leakage of cell contents. Nixiclin-XL 0.25% Cream 50 gm causes holes in the fungal cell membranes and kills fungi. Thereby, clears fungal infection and provides relief from cracking, burning, scaling and itching of the skin caused due to infections. 

• Itching

• Dry skin

• Redness

• Burning sensation of the skin

Before using Nixiclin-XL 0.25% Cream 50 gm, let your doctor know if you have a history of liver diseases, adrenal gland problems, cataract, glaucoma, diabetes or allergic reactions to any medicine ingredient. Let your doctor know if you plan to become pregnant or already pregnant and a lactating mother. Studies show that there may be harmful effects on the baby; hence Nixiclin-XL 0.25% Cream 50 gm should be used with caution in pregnancy under your doctor's supervision. If you apply Nixiclin-XL 0.25% Cream 50 gm to breasts or nipple for treatment, wash it off while nursing your baby. Nixiclin-XL 0.25% Cream 50 gm is for external use only, so avoid contact with the eyes, the mouth, or intravaginally. Notify the doctor if there is no improvement after one week of treatment for tinea cruris or tinea corporis or two weeks for tinea pedis. When using Nixiclin-XL 0.25% Cream 50 gm in the groin area, patients should use the medication for two weeks only. Prolonged use of Nixiclin-XL 0.25% Cream 50 gm may cause hormonal suppression, Cushing's syndrome, hyperglycemia (increased blood sugar level), and glucosuria (high sugar in urine) in some patients. Apply sunscreen (SPF 30 or higher) whenever you go outdoor in the sunlight. 

Drug-Drug Interaction: Nixiclin-XL 0.25% Cream 50 gm may interact with respiratory-related medicines (budesonide, formoterol), drugs treating HIV/AIDS (ritonavir, cobicistat) and corticosteroids.

Drug-Food Interaction: No drug-food interactions found/established.

Drug-Disease Interaction: Nixiclin-XL 0.25% Cream 50 gm should not be given in patients with a history of allergic reactions to clotrimazole and betamethasone, have diabetes, liver diseases, cataract, glaucoma, adrenal gland problems, and hormonal problems.

• BUDESONIDE
• FORMOTEROL
• COBICISTAT
• RITONAVIR

• Always wear loose-fitting clothes to avoid further sweat and spread of the fungal infection.

• In wet places such as changing rooms and gym showers, don’t walk on barefoot to prevent fungal infections.

• Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.

• Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.

• Do not walk barefoot at places like gym showers to prevent fungal infections.

• Do not scratch the affected area of skin as it can spread the infection to other body parts.

• Avoid sharing towels, combs, bedsheets, shoes or socks with others.

• Wash your bedsheets and towels regularly.

• Follow a candida diet if you suffer from vaginal yeast infection. Candida diet excludes high sugary foods, some dairy products and foods with artificial preservatives.

• Avoid or limit the intake of alcohol and caffeine.

It is advised to reach out to your doctor if the fungal infection symptoms persist or worsen after two treatment weeks. Before applying Nixiclin-XL 0.25% Cream 50 gm, clean and dry the affected area. Avoid contact of Nixiclin-XL 0.25% Cream 50 gm with nose, mouth or eyes. If Nixiclin-XL 0.25% Cream 50 gm comes in contact with these areas accidentally, rinse with water thoroughly. Do not wash the treated areas for a minimum of 3 hours after you apply Nixiclin-XL 0.25% Cream 50 gm. 

Fungal infection is a skin disease in which a fungus attacks the tissue and cause infection. Fungal infections may be contagious (spread from one person to another). Ringworm is a common fungal infection of skin or scalp contagious and causes a rash resembling a worm in a ring shape. Jock itch (also known as tinea cruris) is a fungal infection of the skin that causes an itchy, red rash in warm and moist areas of the body such as the groin, buttocks, and inner thighs. Athlete’s foot (also known as tinea pedis) is a fungal infection that usually starts between the toes, especially in people who have extremely sweaty feet and wear tight-fitting shoes. It occurs most commonly in athletes. It causes itching, burning, or stinging sensation due to a scaly rash. Seborrheic dermatitis is a skin condition that causes an itchy rash with dry, flaky scales on the skin that contains oil glands such as the scalp, face, back, and upper chest.  Fungal infection in nails happens when there is an overgrowth of fungi in, under, or on the nail. Fungal infections usually occur in toenails than fingernails, likely because toes remain under shoes, in a warm, moist environment.