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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Nimozen Infusion is used to prevent brain damage due to subarachnoid haemorrhage. It contains Nimodipine, which relaxes the smooth muscles of the small blood vessels in the brain, thereby allowing narrowed blood vessels to open up. This helps increase blood flow and circulation, reduce blood pressure, and lower the risk of damage caused by insufficient blood flow to the brain after bleeding.
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Composition :

NIMODIPINE-50MG

Manufacturer/Marketer :

Wohltat Life Sciences

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Nimozen Infusion

Nimozen Infusion belongs to a group of medicines called calcium channel blockers indicated as prophylaxis and treatment of ischaemic neurological deficits caused by narrowing of blood vessels following subarachnoid haemorrhage of aneurysmal origin. Subarachnoid haemorrhage is the bleeding around the brain which is usually the result of bleeding from an aneurysm (a weakened area in a blood vessel).
 
Nimozen Infusion contains ‘Nimodipine’ that relaxes the smooth muscles of the small blood vessels in the brain, thereby allowing narrowed blood vessels to open up. This helps in increasing blood flow & circulation, reduces blood pressure, and lowers the risk of damage caused by insufficient blood flow to the brain after bleeding.
 
In some cases, Nimozen Infusion may cause side effects such as low blood pressure, vasodilation, nausea, constipation, flatulence, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
 
Consult your doctor if you are pregnant. Avoid breastfeeding while on treatment with Nimozen Infusion. Drive or operate machinery only if you are alert as Nimozen Infusion may cause dizziness. Nimozen Infusion is not recommended for children below 18 years as safety and effectiveness have not been established. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects/interactions.

Uses of Nimozen Infusion

Prevention of brain damage due to subarachnoid haemorrhage

Directions for Use

Nimozen Infusion will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Nimozen Infusion belongs to the group of medicines called calcium channel blockers indicated as prophylaxis and treatment of ischaemic neurological deficits caused by cerebral vasospasm (narrowing of blood vessels) following aneurysmal subarachnoid haemorrhage. Nimozen Infusion contains ‘Nimodipine’ that relaxes the smooth muscles of the small blood vessels in the brain, thereby allowing narrowed blood vessels to open up. This helps in increasing blood flow & circulation, reduces blood pressure, and lowers the risk of damage caused by insufficient blood flow to the brain after bleeding.

How Nimozen Infusion Works

Nimozen Infusion contains ‘Nimodipine’ that relaxes the smooth muscles of the small blood vessels in the brain, thereby allowing narrowed blood vessels to open up. This helps in increasing blood flow & circulation, reduces blood pressure, and lowers the risk of damage caused by insufficient blood flow to the brain after bleeding.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Nimozen Infusion

  • Low blood pressure
  • Vasodilation
  • Nausea
  • Constipation
  • Flatulence
  • Diarrhoea

What if I have taken an overdose of Nimozen Infusion

As Nimozen Infusion is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Do not take Nimozen Infusion if you are allergic to any of its components. Inform your doctor if you have low blood pressure, fluid retention in the brain, bowel obstruction, epilepsy, alcoholism, heart kidney, or liver problems. Consult your doctor if you are pregnant. Avoid breastfeeding while on treatment with Nimozen Infusion. Drive or operate machinery only if you are alert as Nimozen Infusion may cause dizziness. Nimozen Infusion is not recommended for children below 18 years as safety and effectiveness have not been established.

Drug-Drug Interactions

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NimodipineIndinavir
Critical
NimodipineCobicistat
Critical

Drug-Drug Interactions

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NimodipineIndinavir
Critical
How does the drug interact with Nimozen Infusion 50 ml:
When Nimozen Infusion 50 ml is taken with Indinavir, it can increase the risk of side effects.

How to manage the interaction:
Taking Nimozen Infusion 50 ml with Indinavir is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor if you experience irregular heart rhythm, swelling. Do not discontinue any medications without a doctor's advice.
NimodipineCobicistat
Critical
How does the drug interact with Nimozen Infusion 50 ml:
When Nimozen Infusion 50 ml is taken with Cobicistat, it can increase the risk of side effects.

How to manage the interaction:
Taking Nimozen Infusion 50 ml with Cobicistat is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor if you experience irregular heart rhythm, swelling, and low blood pressure. Do not discontinue any medications without consulting the doctor.
NimodipineMibefradil
Critical
How does the drug interact with Nimozen Infusion 50 ml:
When Mibefradil is taken with Nimozen Infusion 50 ml, it can increase the risk of side effects.

How to manage the interaction:
Taking Nimozen Infusion 50 ml with Mibefradil is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor if you experience any symptoms such as irregular heart rhythm, swelling, and low blood pressure. Do not discontinue any medications without consulting the doctor.
NimodipineTelaprevir
Critical
How does the drug interact with Nimozen Infusion 50 ml:
When Telaprevir is taken with Nimozen Infusion 50 ml, it can increase the risk of side effects.

How to manage the interaction:
Taking Nimozen Infusion 50 ml with Telaprevir is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor if you experience any symptoms such as irregular heart rhythm, swelling, and low blood pressure. Do not discontinue any medications without a doctor's advice.
NimodipineTelithromycin
Critical
How does the drug interact with Nimozen Infusion 50 ml:
When Nimozen Infusion 50 ml is taken with Telithromycin, it can increase the risk of side effects.

How to manage the interaction:
Taking Nimozen Infusion 50 ml with Telithromycin is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor if you experience any symptoms such as irregular heart rhythm, swelling, and low blood pressure.
NimodipineAtazanavir
Critical
How does the drug interact with Nimozen Infusion 50 ml:
When Atazanavir is taken with Nimozen Infusion 50 ml, it can increase the risk of side effects.

How to manage the interaction:
Taking Nimozen Infusion 50 ml with Atazanavir is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience irregular heart rhythm, swelling, and low blood pressure, consult the doctor. Do not discontinue any medications without a doctor's advice.
NimodipineVoriconazole
Critical
How does the drug interact with Nimozen Infusion 50 ml:
Using Nimozen Infusion 50 ml together with Voriconazole may significantly increase the risk of serous side effects.

How to manage the interaction:
Taking Nimozen Infusion 50 ml with Voriconazole is not recommended, as it may lead to an interaction, but it can be taken if prescribed by the doctor. However, if you experience symptoms such as irregular heart rhythm, swelling, and low blood pressure, consult the doctor. Do not discontinue any medication without consulting a doctor.
NimodipineKetoconazole
Critical
How does the drug interact with Nimozen Infusion 50 ml:
When Nimozen Infusion 50 ml is taken with Ketoconazole, it can increase the blood levels of Nimozen Infusion 50 ml which may lead to serious side effects .

How to manage the interaction:
Taking Ketoconazole with Nimozen Infusion 50 ml is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience -irregular heart rhythm, swelling, and low blood pressure, consult the doctor. Do not discontinue any medications without consulting the doctor.
NimodipineBoceprevir
Critical
How does the drug interact with Nimozen Infusion 50 ml:
When Boceprevir is taken with Nimozen Infusion 50 ml, it can increase the risk of side effects.

How to manage the interaction:
Taking Nimozen Infusion 50 ml with Boceprevir is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor if you experience- irregular heart rhythm, swelling, and low blood pressure. Do not discontinue any medications without a doctor's advice.
NimodipineClarithromycin
Critical
How does the drug interact with Nimozen Infusion 50 ml:
When Nimozen Infusion 50 ml is taken with Clarithromycin, it can increase the risk of side effects.

How to manage the interaction:
Co-administration of Clarithromycin and Nimozen Infusion 50 ml is not recommended as it can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like irregular heart rhythm, swelling, and low blood pressure, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Include foods such as whole-grain bread, low-fat dairy products, lean meat, beans, and fish.
  • Exercise as directed by the physician. It helps in lowering blood pressure, cholesterol, blood sugar and weight.
  • Manage stress with meditation, music, or deep breathing.

Habit Forming

No

Therapeutic Class

CALCIUM CHANNEL BLOCKERS
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Alcohol

Consult your doctor

It is not known whether alcohol affects Nimozen Infusion. Please consult your doctor.

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Pregnancy

Caution

Please inform your doctor if you are pregnant. Your doctor will weigh the benefits and the risks before prescribing Nimozen Infusion in pregnancy.

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Breast Feeding

Unsafe

Nimozen Infusion is not recommended during breastfeeding. However, if it is prescribed by your doctor, avoid breastfeeding while on treatment with Nimozen Infusion.

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Driving

Caution

Nimozen Infusion may cause dizziness. Drive and operate machinery only if you are alert.

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Liver

Caution

If you have liver disease, please inform your doctor before receiving Nimozen Infusion. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have kidney disease, please inform your doctor before receiving Nimozen Infusion. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Nimozen Infusion is not recommended for children below 18 years as safety and effectiveness have not been established.

FAQs

Nimozen Infusion is used to prevent brain damage due to subarachnoid haemorrhage.
Nimozen Infusion relaxes the smooth muscles of the small blood vessels in the brain, thereby allowing narrowed blood vessels to open up. This helps in increasing blood flow & circulation, reduces blood pressure, and lowers the risk of damage caused by insufficient blood flow to the brain after bleeding.
Nimozen Infusion might impair sperm function. So, talk to your doctor if you are trying to father a child or if you have any concerns regarding this.
Diarrhoea could be a side effect of Nimozen Infusion. Drink plenty of fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if the condition persists or worsens.
Consult your doctor before taking anti-hypertensive medicines whilst on treatment with Nimozen Infusion as it may increase the blood pressure lowering effect of concomitantly used anti-hypertensive medicines. Regular monitoring of blood pressure levels is advised.
Nimozen Infusion may cause constipation in some cases. However, it is not necessary for everyone taking Nimozen Infusion to experience this side effect. If the condition persists or worsens, consult a doctor.
Nimozen Infusion contains Nimodipine which belongs to the group of medicines called calcium channel blockers used to prevent brain damage due to subarachnoid haemorrhage.
Avoid grapefruit and its juice during treatment with Nimozen Infusion as it might increase the blood levels of the medicine. Do not drive or operate machinery as it may cause dizziness.
Nimozen Infusion is administered as a continuous IV infusion by a healthcare professional; do not self-administer.
Nimozen Infusion should not be taken along with the tablet form of nimodipine. However, if needed your doctor may ask you to switch to the tablet form of nimodipine after completion of treatment with Nimozen Infusion.
Nimozen Infusion may cause side effects such as low blood pressure, vasodilation, nausea, constipation, flatulence, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Sco308, First Floor, Sec 38 d Chandigarh, Chandigarh - 160001
Other Info - NIM0427

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