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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:19 PM IST

Nilitis 500 mg Tablet is used to relieve pain, swelling, tenderness, stiffness, and swelling caused by osteoarthritis and rheumatoid arthritis. It contains Nabumetone, which works by blocking the effect of chemical messengers that cause pain, fever, and inflammation. Thereby, it helps treat osteoarthritis and rheumatoid arthritis. In some cases, Nilitis 500 mg Tablet may cause side effects such as diarrhoea, nausea, constipation, stomachache, and wind.

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Prescription drug

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Composition

NABUMETONE-500MG

Manufacturer/Marketer

Ipca Laboratories Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-26

for this medicine

About Nilitis 500 mg Tablet

Nilitis 500 mg Tablet belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) indicated to relieve signs and symptoms of osteoarthritis and rheumatoid arthritis. Osteoarthritis is caused by the breakdown of the joint lining, whereas rheumatoid arthritis is caused by swelling of the joint linings.

Nilitis 500 mg Tablet contains Nabumetone, which works by blocking the effect of chemical messengers that cause pain, fever, and inflammation. Thereby, it helps treat osteoarthritis and rheumatoid arthritis.

In some cases, Nilitis 500 mg Tablet may cause side effects such as diarrhoea, nausea, constipation, stomach ache, and wind. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to the doctor if any of the side effects persist or worsen.

Avoid taking Nilitis 500 mg Tablet during the last three months of pregnancy or if you are breastfeeding. This medicine may cause dizziness; drive only if you are alert. Nilitis 500 mg Tablet is not recommended for children as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Nilitis 500 mg Tablet

Treatment of Osteoarthritis and rheumatoid arthritis

Medicinal Benefits

Nilitis 500 mg Tablet belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), used to relieve pain, swelling, tenderness, stiffness, and swelling caused by osteoarthritis and rheumatoid arthritis. Nilitis 500 mg Tablet contains Nabumetone, which works by blocking the effect of chemical messengers that cause pain, fever, and inflammation.  Thereby, it helps treat osteoarthritis and rheumatoid arthritis.

Directions for Use

Take Nilitis 500 mg Tablet with or after a meal. Swallow the medicine as a whole with a glass of water; do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Nilitis 500 mg Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Indigestion
  • Abdominal pain
  • Dizziness
  • Headache

Drug Warnings

Do not take Nilitis 500 mg Tablet if you are allergic to any of its components, aspirin or NSAIDS, or if you have/had stomach/peptic ulcer, perforation, or bleeding, peptic disease, severe heart failure, liver cirrhosis, kidney failure, or if you are in the last three months of pregnancy or breastfeeding. Inform the doctor if you have/had asthma, stomach problems (Crohn’s disease or ulcerative colitis), liver, kidney or heart problems, high blood pressure, stroke, oedema, autoimmune diseases, diabetes, high cholesterol, infections, are in the first six months of pregnancy, smoker, or if you are above 65 years of age. Nilitis 500 mg Tablet is not recommended for children. Stop taking Nilitis 500 mg Tablet and consult a doctor immediately if you experience difficulty breathing, face or throat swelling, severe rash that may blister, chest pain or sudden numbness and confusion, blood in stools (black/tarry stools), or blood in vomit (dark particles that look like coffee granules). Do not take Nilitis 500 mg Tablet if you have recently had a heart attack unless prescribed by your doctor. Seek emergency medical help immediately if you experience symptoms such as chest pain, weakness in one part or side of the body, shortness of breath, or slurred speech. Nilitis 500 mg Tablet may cause gastrointestinal events, including bleeding, ulceration, and perforation of the stomach or intestines. If you experience any of the following symptoms, stop taking Nilitis 500 mg Tablet and consult your doctor: stomach pain, vomit that is bloody or looks like coffee grounds,  heartburn, blood in the stool, or black and tarry stools.

Drug Interactions

Drug-Drug Interactions: Inform the doctor if you are taking antidepressants (duloxetine, escitalopram, fluoxetine, sertraline), diuretics (hydrochlorothiazide), anti-hypertensive (lisinopril), corticosteroid (prednisone), anti-diabetic (metformin)

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform the doctor if you have asthma, fluid retention, gastrointestinal toxicity, kidney problems, thrombosis, liver disease, anaemia, heart problems, high blood pressure, high potassium levels or platelet aggregation inhibition.

Drug-Drug Interactions Checker List

  • DULOXETINE
  • ESCITALOPRAM
  • FLUOXETINE
  • SERTRALINE
  • HYDROCHLOROTHIAZIDE
  • LISINOPRIL
  • PREDNISONE
  • METFORMIN

Habit Forming

No

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20 minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Special Advise

  • Your doctor may advise regular tests to monitor liver and kidney function.
  • If you are due to undergo CABG surgery (coronary artery bypass graft, a type of heart surgery), you should not take Nilitis 500 mg Tablet right before or right after the surgery.

Disease/Condition Glossary

Osteoarthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation and tenderness.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function. 

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Alcohol

Unsafe

Avoid alcohol consumption during treatment with Nilitis 500 mg Tablet .

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Pregnancy

Caution

Nabumetone belongs to pregnancy category C. Nilitis 500 mg Tablet is not recommended during the last three months of pregnancy. This medicine should be used during pregnancy only if the benefits outweigh the risks. The lowest dose for the shortest time possible should be used.

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Breast Feeding

Unsafe

Please consult the doctor if you are breastfeeding. Your doctor will decide whether to discontinue nursing or the medicine, taking into account the importance of the medicine to the mother.

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Driving

Caution

Nilitis 500 mg Tablet may cause dizziness, tiredness and drowsiness. Do not drive or operate machinery if you experience these symptoms.

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Liver

Caution

Please inform the doctor if you have liver problems before taking Nilitis 500 mg Tablet .

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Kidney

Caution

Please inform the doctor if you have kidney impairment before taking Nilitis 500 mg Tablet .

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Children

Unsafe

Nilitis 500 mg Tablet is not recommended for children as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra.
Other Info - NIL0003

Author Details

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FAQs

Nilitis 500 mg Tablet is used to treat Osteoarthritis and rheumatoid arthritis.
Nilitis 500 mg Tablet works by blocking the effect of chemical messengers that cause pain and inflammation.
Nilitis 500 mg Tablet may be associated with a small increased risk of heart attack or stroke. This risk is more likely with prolonged treatment and high doses. Therefore, avoid exceeding the dose and duration of treatment suggested by the doctor. Also, inform the doctor if you have/had a stroke or heart problems.
Nilitis 500 mg Tablet might make it harder for you to become pregnant. If you are planning for pregnancy, ask your doctor for advice.
Nilitis 500 mg Tablet is neither an antibiotic nor a steroid. It contains Nabumetone which belongs to the class of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs).
Yes, Nilitis 500 mg Tablet helps relieve pain by blocking the effects of COX enzymes which cause pain and inflammation.
Yes, Nilitis 500 mg Tablet is safe if taken in the dose and duration prescribed by the doctor.
If you miss a dose of Nilitis 500 mg Tablet , take it as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.
Yes, Nilitis 500 mg Tablet effectively relieves pain, tenderness, swelling, and stiffness associated with osteoarthritis and rheumatoid arthritis.
Nilitis 500 mg Tablet may cause side effects such as diarrhoea, nausea, constipation, stomach ache, and wind. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to the doctor if any of the side effects persist or worsen.

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