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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Nifetolol 50 mg/20 mg Tablet is used to treat hypertension (high blood pressure). It contains Atenolol and Nifedipine, which works by reducing the heart rate and makes the heart pump blood efficiently throughout the body. Also, it relaxes the blood vessels and lowers the blood pressure. This reduces the risk stroke, heart attack, other heart problems, or kidney problems in the future. It may cause side effects such as blurred vision, sweating, tiredness, dehydration, constipation, dizziness, headache, nausea, cold hands or feet, and muscle cramps. Before using this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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3 Days Returnable

Expires on or after :

Jan-27

About Nifetolol 50 mg/20 mg Tablet

Nifetolol 50 mg/20 mg Tablet is used to treat hypertension (high blood pressure). Hypertension is a medical condition in which the blood exerts high pressure (force exerted by circulating blood) against blood vessels' walls. This condition makes the heart work harder to pump blood into the whole body. Hypertension can cause severe health complications, including stroke, heart failure, heart attack, and kidney failure.

Nifetolol 50 mg/20 mg Tablet contains Atenolol (beta-blocker) and Nifedipine (calcium channel blocker). Atenolol works by reducing the heart rate and making the heart pump blood efficiently throughout the body. Nifedipine works by relaxing the blood vessels; this lowers your blood pressure and reduces your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective and also for the best results.

Take Nifetolol 50 mg/20 mg Tablet as prescribed by your doctor. You are advised to take Nifetolol 50 mg/20 mg Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. In some cases, you may experience blurred vision, sweating, tiredness, dehydration, constipation, dizziness, headache, nausea, cold hands or feet, and muscle cramps. Most of these side effects of Nifetolol 50 mg/20 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not stop taking Nifetolol 50 mg/20 mg Tablet without consulting your doctor since it may worsen your condition and increase the risk of future heart problems. Inform your doctor if you are suffering from kidney, liver, heart diseases, diabetes, gout, and asthma. Please tell your doctor if you are taking any other medicines or have any allergic reactions to Nifetolol 50 mg/20 mg Tablet . Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling. Do not eat grapefruit or drink grapefruit juice while you're taking Nifetolol 50 mg/20 mg Tablet . It can make side effects worse.  If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Nifetolol 50 mg/20 mg Tablet can be prescribed accordingly.

Uses of Nifetolol 50 mg/20 mg Tablet

Treatment of Hypertension (high blood pressure)

Directions for Use

Take Nifetolol 50 mg/20 mg Tablet with or without food or as directed by your physician. Swallow it as a whole with a glass of water. Do not crush, chew, or break it.

Medicinal Benefits

Nifetolol 50 mg/20 mg Tablet treats hypertension (high blood pressure), consisting of Atenolol (beta-blocker) and Nifedipine (calcium channel blocker). Atenolol works by blocking the release of stress hormones (like adrenaline or non-adrenaline), thereby relieving angina (chest pain) and uneven heartbeats (arrhythmias).  Atenolol also protects the heart during the treatment of a heart attack.  Nifedipine works by relaxing the blood vessels; this lowers your blood pressure and reduces your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective and also for the best results. Thus, Nifetolol 50 mg/20 mg Tablet reduces raised blood pressure by minimizing fluid overload (oedema) and reducing the heart's blood-pumping activity.

How Nifetolol 50 mg/20 mg Tablet Works

Nifetolol 50 mg/20 mg Tablet contains Atenolol (beta-blocker) and Nifedipine (calcium channel blocker). Atenolol works by reducing the heart rate and making the heart pump blood efficiently throughout the body. Nifedipine works by relaxing the blood vessels; this lowers your blood pressure and reduces your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Nifetolol 50 mg/20 mg Tablet

  • Blurred Vision 
  • Sweating
  • Tiredness 
  • Dehydration 
  • Constipation 
  • Dizziness 
  • Headache 
  • Nausea 
  • Cold hands or feet 
  • Muscle cramps
  • Difficulty breathing
  • Tightness in the chest

What if I have taken an overdose of Nifetolol 50 mg/20 mg Tablet

Do not take more than the prescribed dose of Nifetolol 50 mg/20 mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not use Nifetolol 50 mg/20 mg Tablet if you are allergic to Nifetolol 50 mg/20 mg Tablet or any of its components. Let your doctor know if you have any history of severe kidney or liver diseases, low potassium levels (hypokalaemia), chest pain (angina), poor blood circulation or controlled heart failure, first-degree heart block, diabetes, thyrotoxicosis (a condition caused by an overactive thyroid gland), liver problems, and adrenal gland diseases. Let your doctor know if you have anuria (kidneys aren't producing urine), fluid or electrolyte imbalance, lupus erythematosus (an autoimmune inflammatory disease-causing scaly red patches on the skin), gout, abnormal heart rhythms, thyroid disorders, and asthma before starting Nifetolol 50 mg/20 mg Tablet . It is essential to let your doctor know if you are a breastfeeding mother before using Nifetolol 50 mg/20 mg Tablet since Indapamide may pass into the breast milk. Please ask your doctor if you plan to conceive or are pregnant before using Nifetolol 50 mg/20 mg Tablet . Nifetolol 50 mg/20 mg Tablet can increase the chances of light-headedness so rise slowly if you are sitting/lying and avoid operating any machine or doing any work that needs mental alertness. Nifetolol 50 mg/20 mg Tablet is not recommended in people less than 18 years of age.

Drug-Drug Interactions

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NifedipineCarbamazepine
Critical
AtenololClonidine
Severe

Drug-Drug Interactions

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NifedipineCarbamazepine
Critical
How does the drug interact with Nifetolol 50 mg/20 mg Tablet 10's:
Coadministration of Nifetolol 50 mg/20 mg Tablet 10's with Carbamazepine can reduce the blood levels of Nifetolol 50 mg/20 mg Tablet 10's, which may make the medication less effective.

How to manage the interaction:
Taking Nifetolol 50 mg/20 mg Tablet 10's with Carbamazepine together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
AtenololClonidine
Severe
How does the drug interact with Nifetolol 50 mg/20 mg Tablet 10's:
Co-administration of Clonidine and Nifetolol 50 mg/20 mg Tablet 10's may lower blood pressure and slower heart rate.

How to manage the interaction:
Although there is a possible interaction between Clonidine and Nifetolol 50 mg/20 mg Tablet 10's, you can take these medicines together if prescribed by a doctor. However, if you experience headaches, slow heartbeat, dizziness, contact a doctor. Do not discontinue the medication without consulting a doctor.
AtenololDolasetron
Severe
How does the drug interact with Nifetolol 50 mg/20 mg Tablet 10's:
Using dolasetron together with Nifetolol 50 mg/20 mg Tablet 10's can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction between Nifetolol 50 mg/20 mg Tablet 10's and Dolasetron, you can take these medicines together if prescribed by a doctor. If you have any of these symptoms, like feeling dizzy, lightheaded, or your heart beating irregularly, it's important to call a doctor right away. Do not stop using any medications without talking to a doctor.
AtenololAceclofenac
Severe
How does the drug interact with Nifetolol 50 mg/20 mg Tablet 10's:
Co-administration of Nifetolol 50 mg/20 mg Tablet 10's with Aceclofenac could increase the risk of low blood pressure.

How to manage the interaction:
Although there is a possible interaction between Nifetolol 50 mg/20 mg Tablet 10's and Aceclofenac, you can take these medicines together if prescribed by a doctor. Consult a doctor if you experience excessive sweating, shortness of breath, palpitations, or chest discomfort. Do not discontinue any medications without consulting a doctor.
AtenololAminophylline
Severe
How does the drug interact with Nifetolol 50 mg/20 mg Tablet 10's:
Coadministration of Nifetolol 50 mg/20 mg Tablet 10's with aminophylline could certainly reduce the efficacy of Nifetolol 50 mg/20 mg Tablet 10's and enhance the effects of aminophylline.

How to manage the interaction:
Taking Nifetolol 50 mg/20 mg Tablet 10's alongside aminophylline can result in an interaction, it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AtenololDisopyramide
Severe
How does the drug interact with Nifetolol 50 mg/20 mg Tablet 10's:
When disopyramide is used with Nifetolol 50 mg/20 mg Tablet 10's, it may increase the effects of disopyramide.

How to manage the interaction:
When Nifetolol 50 mg/20 mg Tablet 10's is used with disopyramide, it can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience dizziness, fainting, heart palpitations, slow or fast pulse, or irregular heartbeats, consult the doctor immediately. Do not stop using any medication without consulting a doctor.
AtenololFingolimod
Severe
How does the drug interact with Nifetolol 50 mg/20 mg Tablet 10's:
Using Nifetolol 50 mg/20 mg Tablet 10's with fingolimod can result in an abnormally slow heart rate, which can lead to significant heart issues.

How to manage the interaction:
Taking Nifetolol 50 mg/20 mg Tablet 10's and fingolimod together may result in an interaction, it can be taken if a doctor has recommended it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, chest pain, or heart palpitations during treatment, consult the doctor. Do not discontinue any medications without consulting a doctor.
AtenololPropranolol
Severe
How does the drug interact with Nifetolol 50 mg/20 mg Tablet 10's:
Taking Nifetolol 50 mg/20 mg Tablet 10's and propranolol together may lower your blood pressure excessively which may lead to side effects.

How to manage the interaction:
Combined use of Nifetolol 50 mg/20 mg Tablet 10's and propranolol may result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
AtenololAcebutolol
Severe
How does the drug interact with Nifetolol 50 mg/20 mg Tablet 10's:
Coadministration of Nifetolol 50 mg/20 mg Tablet 10's and Acebutolol they both may enhance blood pressure-lowering effect.

How to manage the interaction:
Taking Nifetolol 50 mg/20 mg Tablet 10's and acebutolol together can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AtenololDiltiazem
Severe
How does the drug interact with Nifetolol 50 mg/20 mg Tablet 10's:
Taking Nifetolol 50 mg/20 mg Tablet 10's and diltiazem together may lead to increased side effects.

How to manage the interaction:
Taking Nifetolol 50 mg/20 mg Tablet 10's and diltiazem together can result in an interaction, it can be taken if a doctor has recommended it. However, if you experience tiredness, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest discomfort, increased or reduced heartbeat, or irregular heartbeat, consult the doctor. Do not discontinue any medications without consulting doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Keep your weight under control with a body mass index (BMI) between 19.5 and 24.9.

  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.

  • Limit sodium chloride intake (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

  • If you are taking alcohol, use only one serving for women and two servings for men.

  • Quit smoking to lower the risk of heart diseases. 

  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress.

  • Monitor your blood pressure daily, and if you notice any fluctuations frequently, please contact your doctor immediately.

  • Try including heart-healthy omega 3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil that help in lowering your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Nifetolol 50 mg/20 mg Tablet Substitute

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Alcohol

Unsafe

Alcohol may lower your blood pressure. It would help if you avoided or limit consuming alcohol whilst taking this medicine.

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Pregnancy

Unsafe

Nifetolol 50 mg/20 mg Tablet contains atenolol, a category D pregnancy drug, and it may cause fetal defects in the baby.

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Breast Feeding

Unsafe

Do not take Nifetolol 50 mg/20 mg Tablet as it may pass through the breast milk.

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Driving

Unsafe

Nifetolol 50 mg/20 mg Tablet may cause side effects such as dizziness, drowsiness, which could affect your ability to drive.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before using Nifetolol 50 mg/20 mg Tablet .

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before using Nifetolol 50 mg/20 mg Tablet .

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Children

Caution

Nifetolol 50 mg/20 mg Tablet is not recommended for use in people below 18 years of age.

FAQs

Nifetolol 50 mg/20 mg Tablet is used to treat hypertension (high blood pressure).
Nifetolol 50 mg/20 mg Tablet consists of Atenolol and Nifedipine medicines. Atenolol is a 'beta-blocker and treats high blood pressure, angina (chest pain), and uneven heartbeats (arrhythmias) by reducing the heart rate and making the heart pump blood throughout the body. Nifedipine works by relaxing the blood vessels; this lowers your blood pressure and reduces your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future.
It is advised to consult your doctor before taking Nifetolol 50 mg/20 mg Tablet if you have a history of severe kidney or liver diseases, low potassium levels (hypokalaemia), diabetes, gout, abnormal heart rhythms, thyroid disorders and asthma.
Yes, Nifetolol 50 mg/20 mg Tablet contains nifedipine, which can cause a sudden drop in blood pressure, especially when you start taking Nifetolol 50 mg/20 mg Tablet , to avoid a sudden drop, please get up gently when sitting down to avoid dizziness.
Even though your blood pressure becomes normal after using Nifetolol 50 mg/20 mg Tablet , it may switch back to high ranges if you stop using it. Your doctor may change the dosing schedule based on your blood pressure range.
If you forget to take Nifetolol 50 mg/20 mg Tablet at any time, take it as soon as you remember, then continue to take it at the usual times. Do not take a double dose to make up for a forgotten dose.

Country of origin

India

Manufacturer/Marketer address

No. 41, 3rd Cross, 5th Block, Rajajinagar, Bengaluru ? 560 010, Karnataka , India.
Other Info - NIF0006

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