Nexmet 25mg Tablet is used to relieve symptoms caused by osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis, such as stiffness, swelling and joint pain. Nexmet 25mg Tablet is also used to treat acute gouty arthritis, musculoskeletal pain, lower back pain, period pain, and pain following joint and bone surgery.

Nexmet 25mg Tablet works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

You are advised to take Nexmet 25mg Tablet as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as headache, dizziness, diarrhoea, vomiting, and constipation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Nexmet 25mg Tablet can increase your risk of fatal heart attack or stroke. So, if you have had any recent heart surgery, do not use Nexmet 25mg Tablet. Nexmet 25mg Tablet increases the chances of stomach ulcers and bleeding. To treat your condition effectually, continue taking Nexmet 25mg Tablet for as long as your doctor has prescribed. To avoid recurring symptoms, do not stop it midway. Do not take Nexmet 25mg Tablet if you are pregnant or breastfeeding unless prescribed. Nexmet 25mg Tablet causes drowsiness and dizziness, so drive with caution. Nexmet 25mg Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Nexmet 25mg Tablet as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Nexmet 25mg Tablet belongs to the group of painkillers known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs). Nexmet 25mg Tablet is used to relieve symptoms caused by osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis, such as stiffness, swelling and joint pain. Nexmet 25mg Tablet is also used to treat acute gouty arthritis, musculoskeletal pain, lower back pain, period pain, and pain following joint and bone surgery. Nexmet 25mg Tablet works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

• Headache,
• Dizziness
• Diarrhoea
• Vomiting
• Constipation

Nexmet 25mg Tablet can increase your risk of having a fatal heart attack, chest pain (angina) or stroke. So, tell your doctor that you are using Nexmet 25mg Tablet before undergoing heart bypass surgery (CABG) or graft surgery. Do not take Nexmet 25mg Tablet if you are allergic to Nexmet 25mg Tablet, have severe heart failure, have suffered bleeding problems such as bleeding from stomach or bowels while taking any pain killers or you have liver or kidney problems. Do not take Nexmet 25mg Tablet if you are pregnant or breastfeeding unless prescribed. Nexmet 25mg Tablet causes drowsiness and dizziness, so drive only if you are alert. Nexmet 25mg Tablet should not be given to children as the safety have not been established. Avoid consuming alcohol along with Nexmet 25mg Tablet as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Stop taking Nexmet 25mg Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in intestine or stomach like blood in stools.

Drug-Drug Interactions: Nexmet 25mg Tablet may have interaction with ibuprofen, naproxen, and aspirin (used to relieve pain), duloxetine (used to treat depression), metoprolol (used to treat high blood pressure), celecoxib, and prednisone (used to treat arthritis).

Drug-Food Interactions: Avoid consuming alcohol along with Nexmet 25mg Tablet as it could lead to increased drowsiness and dizziness. It could also elevate the risk of stomach bleeding.

Drug-Disease Interactions: Nexmet 25mg Tablet should not be given in patients with heart failure, fluid retention (oedema), asthma, gastrointestinal toxicity, high blood pressure, hyperkalemia (high levels of potassium), thrombosis (formation of clots), anaemia (low red blood cells), rash, platelet aggregation inhibition, CNS problems, kidney and liver toxicity.

• IBUPROFEN
• NAPROXEN
• ASPIRIN
• DULOXETINE
• METOPROLOL
• CELECOXIB
• PREDNISONE

• Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.

• Performing yoga may also help in improving joint flexibility and pain management.

• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

• Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.

• Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.

• De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.

• Acupuncture, massage and physical therapy may also be helpful.

• Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

• Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.

• Avoid smoking and alcohol consumption.

• Your doctor may advise you to undergo tests for monitoring liver and kidney functioning, blood cell levels, effect on stomach and intestine.

• Regular monitoring of eye-sight via eye tests is advised if you have rheumatoid arthritis.

• Monitoring of blood pressure levels and heart functioning is recommended.

Osteoarthritis: It is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms of osteoarthritis include pain, inflammation, stiffness, and tenderness. The main reason for osteoarthritis is age, the older you are, the more likely you could get osteoarthritis, thus known as degenerative disease, meaning that the joints wear-out as a person ages. Other reasons include a past injury such as torn cartilage, dislocated joints and ligament injuries.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Symptoms of rheumatoid arthritis include stiffness, pain, swelling, deformities and loss of joint function.

Ankylosing spondylitis: It causes pain and stiffness in the spine, which starts in the lower back and can spread to the neck, damaged joints or other parts of the body. Symptoms of ankylosing spondylitis include decreased flexibility, which usually leads to a hunched-forward posture and pain in the back and joints.