Nevir-ER Tablet is an antiretroviral medicine used in the treatment of HIV. Human Immunodeficiency Virus (HIV) is a retroviral infection that attacks and damages the cells of the immune system. This weakens the ability to fight against infections and diseases. If this condition is left untreated, it can lead to Acquired Immuno Deficiency Syndrome (AIDS). Nevir-ER Tablet is combined with other antiretroviral medicines to treat HIV infection.

Nevir-ER Tablet contains Neviparine, which belongs to the class of non-nucleoside reverse transcriptase inhibitor (NNRTI). It works by inhibiting the HIV reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of DNA replication and thereby prevents further spread of infection.

Nevir-ER Tablet may cause side effects such as nausea, headache, abdominal pain, loss of appetite, vomiting, fatigue, diarrhoea, myalgia (muscle pain), skin rash and other allergic reactions. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. Nevir-ER Tablet should be taken as advised by your doctor. Your doctor will decide the dose of the medicine based on your health condition. Do not take more than the recommended dose.

Nevir-ER Tablet should be avoided if you are allergic to it. This medicine is contraindicated in patients with moderate to severe hepatic impairment or used as an occupational or non-occupational post-exposure prophylaxis. Nevir-ER Tablet is known you cause fatal or non-fatal hepatotoxicity and skin disorders. Hence, careful monitoring should be done during the first 18 weeks of the treatment initiation. Before taking this medicine, inform your doctor if you have liver/kidney disease, hypersensitivity reactions, Stevens-Johnson syndrome, toxic epidermal necrolysis, cirrhosis, or hepatic fibrosis. If you are pregnant and breastfeeding, let your doctor know before taking Nevir-ER Tablet . Nevir-ER Tablet should be used in children only if recommended by the doctor. 

Nevir-ER Tablet contains Neviparine, which belongs to the class of non-nucleoside reverse transcriptase inhibitor (NNRTI). It works by inhibiting the HIV reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of DNA replication and thereby prevents further spread of infection. Nevir-ER Tablet is used in combination with other antiretroviral medicines to help reduce the symptoms, control the infection, and prevent opportunistic infections effectively. It also helps in improving the quality of life of a patient with HIV. 

• Nausea
• Abdominal pain
• Vomiting
• Joint ache
• Fatigue
• Loss of appetite
• Myalgia
• Skin rash
• Diarrhoea
• Headache

Nevir-ER Tablet should be avoided if you are allergic to it. This medicine is contraindicated in patients with moderate to severe hepatic impairment or used as an occupational or non-occupational post-exposure prophylaxis. This medicine should only be prescribed in patients with CD4+ greater than 250 cells/mm3 (females) and 400 cells/mm3 (males). Inform your doctor about your medical history and the medicines you take to prevent possible interactions. Nevir-ER Tablet is known you cause fatal or non-fatal hepatotoxicity and skin disorders. Hence, careful monitoring should be done during the first 18 weeks of the treatment initiation. If the patient develops any signs or symptoms of hepatitis, increased transaminase, rash, or hypersensitivity reactions, Nevir-ER Tablet should be discontinued immediately. This medicine may cause dizziness; hence, avoid driving or operating machines while taking Nevir-ER Tablet . Before taking this medicine, inform your doctor if you have liver/kidney diseases, hypersensitivity reactions, Stevens-Johnson syndrome, toxic epidermal necrolysis, cirrhosis, or hepatic fibrosis. If pregnant and breastfeeding, inform your doctor before taking Nevir-ER Tablet . Nevir-ER Tablet should be used in children only if recommended by the doctor. If prescribed, the child should be carefully monitored for any changes. Nevir-ER Tablet treats the infection but does not cure or prevent it.

Drug-Drug Interactions: Nevir-ER Tablet may interact with contraceptives (ethyl estradiol, norethindrone), immunosuppressants (cyclosporin, sirolimus, tacrolimus), anti-cancer medicine (cyclophosphamide), Antiarrhythmic drugs (Amiodarone, disopyramide), anticonvulsants (carbamazepine, clonazepam), antifungals (itraconazole), antiviral medicine (ritonavir, indinavir, lopinavir).

Drug-Food Interactions: Avoid smoking and alcohol consumption.

Drug-Disease Interactions: Inform your doctor if you have moderate to severe hepatic impairment, Stevens-Johnson syndrome, toxic epidermal necrolysis, cirrhosis, hepatic fibrosis, and other skin disorders before starting treatment with Nevir-ER Tablet .

• CYCLOSERINE
• TACROLIMUS
• SIROLIMUS
• AMIODARONE
• CARBAMAZEPINE
• CLONAZEPAM
• RITONAVIR
• ITRACONAZOLE
• LOPINAVIR

• Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as vegetables and fruit as it helps to boost your immune system. Try to take lean protein and whole grains.
• Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
• Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
• Get tested for other sexually transmitted infections, such as gonorrhoea or syphilis.
• Try to reduce emotional and physical stress by spending time with your family or doing whatever makes you happy.
• Drink more fluids and avoid alcoholic beverages to prevent dehydration.  
• Never share personal items with body fluids or blood on them, such as razor blades or toothbrushes.
• Avoid sharing used needles, other injection or drug equipment.

• Get an HIV test done at least every three months.
• Nevir-ER Tablet may still develop infections or other illnesses associated with HIV infection or AIDS. So, people taking Nevir-ER Tablet should be carefully monitored throughout the treatment.
• Regular liver function and CBC tests while taking Nevir-ER Tablet are advised.

HIV Infection: Human Immunodeficiency Virus (HIV) is a retroviral infection that attacks and damages the cells of the immune system. This weakens the ability to fight against infections and diseases. If this condition is left untreated, it can lead to Acquired Immuno Deficiency Virus (AIDS). Symptoms of HIV include headache, fever, chills, joint pain, fatigue, swollen lymph nodes, sore throat, mouth nodes, muscle aches, etc. Nevir-ER Tablet helps reduce the symptoms, control the infection, and also helps improve the HIV patient’s quality of life.