Nestacort Suspension

Nestacort Suspension is used to treat Duchene muscular dystrophy in adults and children above 2 years of age. Autoimmune disease is a health disorder in which the immune system doesn't work normally & is unable to distinguish between a foreign cell & a native cell. This condition results in an immune system that starts to attack native cells & organs, leading to medical problems like Duchenne muscular dystrophy.

Nestacort Suspension is an immunosuppressive drug that works by binding to immune system cells and turns off the receptors that lead to their abnormal functioning or damaging effects. Nestacort Suspension binds to immune cells, resulting in the inhibition of inflammation & autoimmune diseases that occur due to the production of chemicals called cytokines responsible for inflammation. Thus, a Nestacort Suspension class of drugs is beneficial in autoimmune diseases and inflammation that causes harm in various organs, especially in joints in arthritis & skin psoriasis. Nestacort Suspension makes organ transplantation possible & treats muscle disorders like Duchenne muscular dystrophy.

Nestacort Suspension is available in both oral tablet and suspension dosage forms. The tablet form of Nestacort Suspension can be taken with or without food and swallowed whole with a water glass. Do not crush, chew or break it. The liquid form of Nestacort Suspension can be taken as advised by your doctor with a measuring cup. Your doctor will recommend how often you take Nestacort Suspension based on your medical condition. Some people may experience nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremors, nervousness, diarrhoea and fast heartbeats. Most of these side effects of Nestacort Suspension do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Do not quit taking deflazacort without consulting your physician. Symptoms such as loss of appetite, a disturbed stomach, vomiting, drowsiness, confusion, headache, fever, joint and muscle pain, peeling skin, and weight loss may be caused by stopping the medication suddenly.

Before starting Nestacort Suspension, please inform your doctor that you are allergic (hypersensitive) to Nestacort Suspension. Extra care is to be taken when a patient has an already existing infection being treated (systemic infection) or has recently had some live virus vaccines. Doctors' consultation is required as Nestacort Suspension is not safe to use during pregnancy.

Nestacort Suspension is beneficial in inflammatory diseases, including asthma, arthritis, and allergies. It is used in the treatment of Duchenne muscular dystrophy (DMD). It raises the amount of glucocorticoid in the body. It works by reducing the formation of inflammatory substances and suppressing immunity to prevent self-damage caused by the immune system (auto-immune reactions occurring in organ transplants, autoimmune diseases, or cancer). Nestacort Suspension is a steroid that interacts with overactive immune cells, slows their activity, and decreases the damaging effects they cause in the body. 

Most of the side effects of Nestacort Suspension do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Common side effects include upper respiratory tract infection, excessive abdominal fat, runny or stuffy nose, skin redness, irritability, abdominal discomfort or pain, irregular behaviour, fever, back pain, acne, nausea, restlessness, nosebleeds and stretch marks.

Patients with a history of tuberculosis (TB), heart disease or heart failure stomach disorders (gastritis, peptic ulcer), diabetes (including family history), osteoporosis (bone disease), myasthenia gravis (muscle weakness), depression, mental distress, history of muscular problems caused by corticosteroids, kidney & liver dysfunction (including hepatic insufficiency and cirrhosis), should consult a doctor before using Nestacort Suspension.  This medicine is not recommended for children less than 5 years of age, lactating mothers and pregnant women. Avoid going near people who are sick or infected while using Nestacort Suspension. Before taking Nestacort Suspension for at least, 4-6 weeks do not take any live vaccine as it may cause severe allergic reactions. 

Drug-Drug interaction: Nestacort Suspension interact with anti-tuberculosis (anti TB) drugs like rifampicin, rifabutin, pain-relieving drugs like carbamazepine, Anti-seizure drugs like phenobarbitone, phenytoin & pyrimidine & antifungal like ketoconazole.

Drug-Food interaction: Not advised to be taken with grapefruit or its juice.

Drug-Disease interaction:  Care should be exercised when Nestacort Suspension is administered in patients with diabetes, cataracts, Thyroidism, blood pressure, kidney diseases, glaucoma & herpes.

• RIFAMPICIN
• RIFABUTIN
• CARBAMAZEPINE
• PHENOBARBITONE
• PHENYTOIN
• PRIMIDONE

• While taking Nestacort Suspension and for at least 4-6 weeks before you start taking it. If you are taking Nestacort Suspension, so do not receive a 'live' vaccine or you could develop a serious infection.  
• Do not eat grapefruit or drink grapefruit juice while taking this medication as grapefruit has interaction with Nestacort Suspension.
• Regular eye check-ups, bone mineral test and liver function test is suggested while using Nestacort Suspension. 

Autoimmune disease: This is a group of disorders in which the immune system doesn't work properly due to various genetic & environmental reasons that start attacking normal cells, producing various chemicals resulting in unwanted and hazardous effects in patients. The overactive immune system leads to various symptoms that affect day-to-day life and promote diseases like arthritis and muscular weakness. The immune system can also damage the organ which has been transplanted to the patient from another person due to having different blood groups/antigens of the donor patient's organ. The immune system considers it a foreign, harmful body, leading to complications after transplanting an organ like a kidney, liver, or heart.