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Prescription drug
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Manufacturer/Marketer

Jenburkt Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-25

for this medicine

About Nervijen-NP Tablet

Nervijen-NP Tablet is a combination medicine indicated to manage neuropathic pain associated with diabetic peripheral neuropathy and postherpetic neuralgia. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, and evoked pain (pain caused by events usually not painful).

Nervijen-NP Tablet is a combination of three drugs: Methylcobalamin (vitamin), Nortriptyline (antidepressant), and Pregabalin (anti-convulsant). Methylcobalamin is a vitamin that aids in producing myelin, a substance that protects nerve fibres and regenerates damaged nerve cells. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Pregabalin reduces pain by interfering with pain messages travelling through the brain and down the spine. Together, Nervijen-NP Tablet helps to treat neuropathic pain.

Take Nervijen-NP Tablet as prescribed. Based on your medical condition, your doctor will decide the dose and duration. In some cases, Nervijen-NP Tablet may cause dizziness, sleepiness, nausea, blurred vision, peripheral oedema (swelling of the lower legs and hands), weight gain, and dry mouth. The majority of these side effects do not necessitate medical attention and will subside gradually over time. However, if you are experiencing these side effects regularly, you should consult your doctor.

Please do not take Nervijen-NP Tablet if you are allergic to any of its ingredients. Consult your doctor before taking Nervijen-NP Tablet if you are pregnant or breastfeeding. Nervijen-NP Tablet may cause drowsiness and dizziness, so drive only if you are alert. Nervijen-NP Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Nervijen-NP Tablet as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Nervijen-NP Tablet

Treatment of Neuropathic pain

Medicinal Benefits

Nervijen-NP Tablet is a combination of three drugs: Methylcobalamin (a form of vitamin B), Nortriptyline (antidepressant), and Pregabalin (anti-convulsant). Nervijen-NP Tablet is indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, etc. Methylcobalamin aids in producing myelin, a substance that protects nerve fibres and regenerates damaged nerve cells. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Pregabalin reduces pain by interfering with pain messages travelling through the brain and down the spine. Together, Nervijen-NP Tablet helps to treat neuropathic pain.

Side Effects of Nervijen-NP Tablet

  • Constipation
  • Dry mouth
  • Headache
  • Feeling sleepy, tired or dizzy
  • Diarrhoea

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to any of the ingredients in Nervijen-NP Tablet , do not consume it. Please do not stop taking Nervijen-NP Tablet without first consulting your doctor, as this may result in withdrawal symptoms. If you are pregnant or breastfeeding, do not take Nervijen-NP Tablet unless your doctor has prescribed it. Nervijen-NP Tablet may cause drowsiness and dizziness, therefore drive only if you are alert. Nervijen-NP Tablet is not recommended for children as safety and effectiveness have not been established. Avoid drinking alcohol while taking Nervijen-NP Tablet as it may cause drowsiness and sleepiness. If you have suicidal thoughts, consult your doctor right away.

Therapeutic Class

MISCELLANEOUS

Drug Interactions

Drug-Drug Interactions: Nervijen-NP Tablet may have interaction with antidepressant medications (e.g. duloxetine, sertraline, escitalopram), pain killer medications (e.g. codeine, hydrocodone, morphine, oxycodone, tramadol, acetaminophen), anti-convulsant medications (e.g. topiramate), anti-anxiety medications (e.g. alprazolam), sedative-hypnotics medications (e.g. zolpidem), antihistamine medications (e.g. diphenhydramine, cetirizine), muscle relaxant medications (e.g. cyclobenzaprine), antiemetic medications (e.g. ondansetron), and herbal medications to treat depression (e.g. St John's wort).

Drug-Food Interactions: Avoid alcohol consumption while taking Nervijen-NP Tablet as it might cause increased drowsiness and sleepiness.

Drug-Disease Interactions: Use Nervijen-NP Tablet with medical advice if you have had anticholinergic effects, cardiovascular disease, pheochromocytoma, acute myocardial infarction recovery, cardiovascular disease, depression, seizure disorders, drug dependence, suicidal tendency, angioedema, creatine kinase elevations, peripheral oedema, PR interval prolongation, bone marrow suppression, diabetes, renal/liver disease, schizophrenia/bipolar disorder, hyper/hypoglycemia, schizophrenia, thyroid disorders and urinary retention.

Drug-Drug Interactions Checker List

  • DULOXETINE
  • SERTRALINE
  • ESCITALOPRAM
  • CODEINE
  • HYDROCODONE
  • MORPHINE
  • OXYCODONE
  • TRAMADOL
  • ACETAMINOPHEN
  • TOPIRAMATE
  • ALPRAZOLAM
  • ZOLPIDEM
  • DIPHENHYDRAMINE
  • CETIRIZINE
  • CYCLOBENZAPRINE
  • ONDANSETRON
  • ST JOHN'S WORT

Diet & Lifestyle Advise

  • Include vitamin B and D-rich foods in your diet.

  • Cayenne pepper should be included in your diet because it can help with neuropathic pain.

  • Exercising regularly helps to improve overall health and combat pain.

  • Rest well and get plenty of rest.

  • Taking a warm bath can be very relaxing.

  • Avoid smoking and drinking alcohol.

  • Meditation and yoga can reduce stress, pain sensitivity and improve coping skills.

  • Acupuncture, by stimulating pressure points, can be beneficial.

  • Massages with essential oils can help increase circulation.

Habit Forming

No

What if I have taken an overdose of Nervijen-NP Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Nervijen-NP Tablet may include irregular heartbeats, severe drowsiness, vision problems, confusion, hallucinations, agitation, stiff muscles, overactive reflexes, vomiting, feeling hot or cold, feeling like you might pass out, seizures, or coma. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Special Advise

Nervijen-NP Tablet contains Nortriptyline (antidepressant), which can lead to suicidal thoughts. Suicidal thoughts or behaviour should be closely monitored in people taking Nervijen-NP Tablet . If you have suicidal thoughts, don't be afraid to talk to your doctor right away.

Disease/Condition Glossary

Neuropathic pain: Neuropathic pain is caused due to damaged sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, which is felt as prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also familiar with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury. The body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping and evoked pain (pain caused by events usually not painful).

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Nervijen-NP Tablet as it may increase drowsiness and sleepiness.

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Pregnancy

Caution

If you're pregnant, don't take Nervijen-NP Tablet unless your doctor tells you to. Please consult your doctor if you have any concerns about this; your doctor will only prescribe if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor as there is no substantial research yet on the use of Nervijen-NP Tablet in breastfeeding/nursing mothers.

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Driving

Unsafe

Nervijen-NP Tablet causes drowsiness, sleepiness and blurred vision. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Nervijen-NP Tablet should not be given to children as the safety and efficacy have not been established.

Country of origin

INDIA

Manufacturer/Marketer address

Nirmala Apartments,93, Jayprakash Road, Andheri (West),Mumbai - 400 058. India.
Other Info - NER0275

Author Details

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FAQs

Nervijen-NP Tablet is used to treat neuropathic pain associated with diabetic peripheral neuropathy and postherpetic neuralgia.
Nervijen-NP Tablet contains Methylcobalamin, Nortriptyline, and Pregabalin. Methylcobalamin aids in producing myelin, a substance that protects nerve fibres and regenerates damaged nerve cells. Nortriptyline alters the way nerves receive pain signals, thereby decreasing pain. Pregabalin reduces pain by interfering with pain messages travelling through the brain and down the spine. Together, Nervijen-NP Tablet helps to treat neuropathic pain.
Dry mouth could be a side-effect of Nervijen-NP Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Do not stop taking Nervijen-NP Tablet without consulting your doctor, as this could result in withdrawal symptoms. Continue taking Nervijen-NP Tablet for as long as prescribed to treat your condition effectively. If you experience any difficulty while taking Nervijen-NP Tablet , do not be afraid to speak with your doctor.
Nervijen-NP Tablet is used to treat diabetic neuropathy. Diabetic neuropathy is a condition that causes nerve damage due to high blood glucose levels. It primarily affects the nerves in the legs and feet.
Nervijen-NP Tablet may cause peripheral oedema. The swelling of the hands and lower legs are known as peripheral oedema. If you experience oedema, avoid sitting or standing for extended periods. Raise your legs by laying down and placing a pillow under them.

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