NEOPRATE INJECTION 5ML belongs to the group of medicines called anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. Additionally, NEOPRATE INJECTION 5ML is also used to treat bipolar disorder. Epilepsy is a central nervous system disorder characterized by a sudden rush of electrical activity in the brain leading to seizures, unusual behavior, and loss of awareness. Bipolar disorder is a mental health disorder associated with episodes of mood swings ranging from manic highs to depressive lows. 
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NEOPRATE INJECTION 5ML contains 'Sodium valproate', which decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. NEOPRATE INJECTION 5ML increases the amount of a chemical substance called GABA; this helps block the nerve transmission across the brain and provides a calming effect. Thereby helps treat bipolar disorder. 
 
NEOPRATE INJECTION 5ML will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side-effects such as sleepiness, dizziness, nausea, headache, and asthenia (weakness). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

If you are of childbearing age, use effective contraception while on treatment with NEOPRATE INJECTION 5ML. Inform your doctor before taking NEOPRATE INJECTION 5ML if you are pregnant or breastfeeding. Do not drive or operate machinery as NEOPRATE INJECTION 5ML may cause sleepiness and dizziness. Avoid consuming alcohol along with NEOPRATE INJECTION 5ML as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

NEOPRATE INJECTION 5ML belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy (fits). NEOPRATE INJECTION 5ML decreases the excessive and abnormal nerve activity in the brain, thereby controlling seizures. Additionally, NEOPRATE INJECTION 5ML is also used to treat bipolar disorder. NEOPRATE INJECTION 5ML increases the amount of a chemical substance called GABA; this helps block the nerve transmission across the brain and provides a calming effect. Thereby helps treat bipolar disorder. 

• Somnolence (sleepiness)
• Dizziness
• Nausea
• Headache
• Asthenia (weakness)
• Paresthesia (prickling or burning sensation)

Do not take NEOPRATE INJECTION 5ML if you are allergic to any of its contents, if you have urea cycle problems, mitochondrial disorders, or hepatic disease/dysfunction. Inform your doctor if you have/had liver problems, porphyria (blood disorder), diabetes, immune system disorder, bleeding problems, systemic lupus erythematosus (a rare skin condition), or kidney problems. NEOPRATE INJECTION 5ML may cause hepatotoxicity (liver damage); consult your doctor if you experience symptoms such as weakness, facial swelling, vomiting, malaise (general discomfort), lethargy (lack of energy or enthusiasm), and anorexia (eating disorder). NEOPRATE INJECTION 5ML may also cause pancreatitis (inflammation of the pancreas); consult your doctor if you experience symptoms such as abdominal pain, vomiting, nausea, and/or anorexia (eating disorder).

Drug-Drug Interactions: NEOPRATE INJECTION 5ML may interact with pain killers (aspirin), anti-epileptics (phenobarbital, primidone, phenytoin, carbamazepine, topiramate, lamotrigine, felbamate, ethosuximide), blood thinner (warfarin), anti-HIV (zidovudine), anti-depressant (diazepam, amitriptyline, nortriptyline), antimycobacterial (rifampin), 

Drug-Food Interactions: Avoid alcohol consumption while taking NEOPRATE INJECTION 5ML as it might cause increased dizziness and sleepiness. 

Drug-Disease Interactions: Inform your doctor if you have depression, liver disease, urea cycle disorders, suicidal tendency, HIV disease, hereditary mitochondrial disorders, or thrombocytopenia (low levels of platelets).

• ASPIRIN
• PHENOBARBITAL
• PHENYTOIN
• PRIMIDONE
• CARBAMAZEPINE
• TOPIRAMATE
• LAMOTRIGINE
• FELBAMATE
• ETHOSUXIMIDE
• WARFARIN
• ZIDOVUDINE
• DIAZEPAM
• AMITRIPTYLINE
• NORTRIPTYLINE
• RIFAMPICIN

• A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.
• Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
• Exercising regularly helps in maintaining weight and improving overall health. 
• Rest well; get plenty of sleep.
• Avoid smoking and alcohol consumption.
• Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
• Have a seizure response plan that helps those around you know what to do.
• Prepare your living area; small changes may help in reducing the risk of physical injury during a seizure.
• Understand what triggers seizures and try reducing or avoiding them.
• Please pay attention to overall health as it can help in reducing seizure activity.
• Install an alarm or emergency device to get assistance during a seizure attack.

• Contact your doctor immediately if you develop suicidal thoughts such as harming or killing yourself.
• Regular tests such as serum liver tests, platelet count, coagulation tests, and ammonia level tests are advised whilst on treatment with NEOPRATE INJECTION 5ML.
• If you are of childbearing age, use effective contraception during the entire treatment with NEOPRATE INJECTION 5ML.
• Consult your doctor immediately if you become pregnant while on treatment with NEOPRATE INJECTION 5ML.

Epilepsy/Seizures: Seizures, also known as fits or convulsions, is a single occurrence of abnormal electrical activity in the brain, whereas epilepsy is a chronic neurological disorder characterized by recurrent seizures. The possible causes of epilepsy include traumatic brain injury, scarring on the brain after a brain injury, high fever, stroke, vascular diseases, lack of oxygen to the brain, brain tumour, and genetic disorders. Symptoms include mood changes, anxiousness, nausea, dizziness, weakness, headache, muscle jerking, spasms, loss of balance, teeth clenching, rapid blinking or eye movements, biting the tongue, confusion, and loss of consciousness.

Bipolar disorder: Bipolar disorder, also known as manic depression or bipolar disease, is a mental health disorder associated with episodes of mood swings ranging from manic highs to depressive lows. Symptoms of manic episodes include high energy, loss of touch with reality, and reduced need for sleep. Symptoms of depressive episodes include low motivation, low energy, and loss of interest in daily life.