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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Nefrosave Keto-DS Tablet is used as a balanced calcium-phosphorus supplement for growing children. It contains Calcium, phosphorus, magnesium, and zinc. It provides Calcium and phosphorous in the correct ratio (i.e. 2:1). Maximum calcium absorption occurs when the proper ratio of Calcium and phosphorus is 2:1. Vitamin D3, Magnesium, and zinc enhance the absorption and utilization of Calcium. It helps to treat or prevent various medical conditions associated with a lack of calcium and phosphorus deficiencies.

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About Nefrosave Keto-DS Tablet

Nefrosave Keto-DS Tablet is used as a balanced calcium-phosphorus supplement for growing children. Unfortunately, many children do not get enough calcium and phosphorus due to less milk consumption or an incomplete diet. Calcium and phosphorus deficiency during the critical growth years leads to poor skeleton formation. Phosphorous deficiency may lead to rickets, muscle weakness, Gum disorders, dental caries, etc.

Nefrosave Keto-DS Tablet contains Calcium, phosphorus, magnesium, and zinc. It provides calcium and phosphorous in the correct ratio. Maximum calcium absorption occurs when the proper ratio of calcium and phosphorus is 2:1. Vitamin D3, Magnesium, and zinc enhance the absorption and utilization of calcium. 

Nefrosave Keto-DS Tablet is for paediatric use only. Give Nefrosave Keto-DS Tablet to children as advised by the doctor. Sometimes, your child may experience certain common side effects, such as bloating, heartburn, dizziness, diarrhoea and constipation. Most of these side effects resolve on their own. If these side effects persist, stop using this medicine and contact your doctor immediately.

Before using Nefrosave Keto-DS Tablet , please inform the doctor of your children's medical conditions, sensitivities, and all drugs they are taking. Continue using Nefrosave Keto-DS Tablet for as long as the doctor has suggested to treat your child's illness effectively. Do not use any other medications or supplements while using Nefrosave Keto-DS Tablet unless recommended by the doctor.

Description

Nefrosave Keto-DS Tablet is a nutraceutical supplement used to manage or control chronic kidney disease (CKD). Combined with a very low-protein or low-protein diet, it aids in delaying the progression of kidney disease during the pre-dialysis period. Alpha-ketoanalogues, L-lysine acetate, L-threonine, L-histidine, L-tyrosine, and L-tryptophan are present in Nefrosave Keto-DS Tablet.

Uses of Nefrosave Keto-DS Tablet

Nefrosave Keto-DS Tablet is used in the treatment of nutritional deficiencies. The detailed uses of Nefrosave Keto-DS Tablet are as follows:
• Avoiding Vitamin D Insufficiency: Nefrosave Keto-DS Tablet is frequently used to avoid vitamin D insufficiency in people whose vitamin D levels are affected by dietary limitations or inadequate sun exposure.
• Support for Bone Health: Calcium absorption, which is necessary to keep bones strong, is greatly aided by vitamin D. Nefrosave Keto-DS Tablet may lessen the chance of fractures by strengthening bones.
• Immune System Support: Having enough vitamin D may improve the immune system's reaction. The immune system can be strengthened by Nefrosave Keto-DS Tablet , particularly during flu season or when there is heightened vulnerability to infections.
• Nutritional Supplement: For people with higher iron needs, such as pregnant women and those following dietary restrictions, Nefrosave Keto-DS Tablet can be used as a nutritional supplement.
• Vitamin C and Phosphorus deficiency: Nefrosave Keto-DS Tablet is frequently used to avoid vitamin C and phosphorus insufficiency in people whose vitamin C levels are affected by dietary limitations.

Directions for Use

• Nefrosave Keto-DS Tablet can be given to your child with meals to help reduce stomach upset. • Follow your doctor's instructions on the dosage and timing of this medication, or use it as per the labelled instructions. • Shake the bottle well before each use. • Give the suggested dose to your child by mouth using the measuring cup provided with the pack. • Avoid using regular household spoons, as they may not measure the dose correctly.

Medicinal Benefits

Nefrosave Keto-DS Tablet is primarily used as a balanced calcium-phosphorus supplement for growing children. It contains Calcium, phosphorus, magnesium, and zinc. Nefrosave Keto-DS Tablet provides calcium and phosphorous in the correct ratio (i.e. 2:1). Maximum calcium absorption occurs when the proper ratio of calcium and phosphorus is 2:1. Vitamin D3, Magnesium, and zinc enhance the absorption and utilization of calcium. Thus, Nefrosave Keto-DS Tablet helps to treat or prevent various medical conditions associated with a lack of calcium and phosphorus deficiencies.

How Nefrosave Keto-DS Tablet Works

Nefrosave Keto-DS Tablet contains Calcium, phosphorus, magnesium, and zinc. It provides calcium and phosphorous in the correct ratio. Maximum calcium absorption occurs when the proper ratio of calcium and phosphorus is 2:1. Vitamin D3, Magnesium, and zinc enhance the absorption and utilization of calcium.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Nefrosave Keto-DS Tablet

Do not give more than the suggested dose. Administering more medication will not improve your symptoms; instead, they may cause poisoning or serious side effects. If you suspect that you may have overdosed Nefrosave Keto-DS Tablet or if your child have experienced any adverse symptoms, please go to the emergency department of the closest hospital or nursing home.

Drug Warnings

The presence of other medical problems or using other medications may affect the use of this medicine. Nefrosave Keto-DS Tablet is not recommended for those who are hypersensitive to any substance in Nefrosave Keto-DS Tablet . So, before using Nefrosave Keto-DS Tablet , let the doctor know about your child's medical conditions, sensitivities, and all medications of your child. Pay attention to how your child reacts to Nefrosave Keto-DS Tablet . If they experience any side effects, discontinue use and contact your paediatrician.

Drug-Drug Interactions

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TryptophanSafinamide
Critical
TryptophanTranylcypromine
Critical

Drug-Drug Interactions

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TryptophanSafinamide
Critical
How does the drug interact with Nefrosave Keto-DS Tablet:
Taking Safinamide with Nefrosave Keto-DS Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Safinamide with Nefrosave Keto-DS Tablet is not recommended as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
TryptophanTranylcypromine
Critical
How does the drug interact with Nefrosave Keto-DS Tablet:
Taking tranylcypromine with Nefrosave Keto-DS Tablet can increase the risk of serotonin syndrome ( high levels of serotonin in body which result in shivering, high fever, diarrhea & muscle stiffness) .

How to manage the interaction:
Taking Tranylcypromine with Nefrosave Keto-DS Tablet is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
TryptophanVenlafaxine
Severe
How does the drug interact with Nefrosave Keto-DS Tablet:
When venlafaxine is taken with Nefrosave Keto-DS Tablet, the risk of serotonin syndrome increases (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
There may be a possibility of interaction between Venlafaxine and Nefrosave Keto-DS Tablet, but it can be taken if prescribed by a doctor. However, if you experience any of the following symptoms: confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, seek immediate medical attention. Do not discontinue any medications without consulting a doctor.
TryptophanClomipramine
Severe
How does the drug interact with Nefrosave Keto-DS Tablet:
The combined use of Nefrosave Keto-DS Tablet with clomipramine can cause serotonin syndrome. Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body, causing signs and symptoms ranging from mild (shivering and diarrhea) to severe (muscle rigidity, fever, and seizures).

How to manage the interaction:
Although taking clomipramine and Nefrosave Keto-DS Tablet together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience symptoms such as confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach pain, nausea, vomiting, and diarrhoea, consult the doctor. Do not discontinue any medications without consulting a doctor.
TryptophanPentazocine
Severe
How does the drug interact with Nefrosave Keto-DS Tablet:
Coadministration of Pentazocine with Nefrosave Keto-DS Tablet may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a interaction between Pentazocine and Nefrosave Keto-DS Tablet, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
TryptophanTrazodone
Severe
How does the drug interact with Nefrosave Keto-DS Tablet:
Using trazodone together with Nefrosave Keto-DS Tablet can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although taking Trazodone and Nefrosave Keto-DS Tablet together can evidently cause an interaction, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
TryptophanVilazodone
Severe
How does the drug interact with Nefrosave Keto-DS Tablet:
When Vilazodone is taken with Nefrosave Keto-DS Tablet, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Vilazodone and Nefrosave Keto-DS Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea-call a doctor right away. Do not stop using any medications without a doctor's advice.
TryptophanDoxepin
Severe
How does the drug interact with Nefrosave Keto-DS Tablet:
The combined use of Nefrosave Keto-DS Tablet and Doxepin can increase the risk of serotonin syndrome(A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Nefrosave Keto-DS Tablet and Doxepin can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, diarrhoea, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
TryptophanRizatriptan
Severe
How does the drug interact with Nefrosave Keto-DS Tablet:
Taking Rizatriptan with Nefrosave Keto-DS Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a possible interaction between Nefrosave Keto-DS Tablet and Rizatriptan, it can be taken if your doctor has advised it. If you notice any of these symptoms like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking of hands and legs, incoordination, stomach cramps, nausea, vomiting, and loose stools, contact a doctor. Do not discontinue any medications without consulting a doctor.
TryptophanAmitriptyline
Severe
How does the drug interact with Nefrosave Keto-DS Tablet:
Combining Nefrosave Keto-DS Tablet with Amitriptyline can increase the risk of serotonin syndrome.(A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Although using Nefrosave Keto-DS Tablet and Amitriptyline together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken amitriptyline. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

If your child has been diagnosed with a calcium and phosphorus deficiency, following the below dietary and lifestyle recommendations is crucial. Additionally:

Monitor Progress: Regular check-ups with your paediatrician are essential to monitor your child's progress and adjust treatment plans if necessary.

Maintain a Balanced Diet: A consistently healthy diet rich in calcium and phosphorus sources are vital for long-term management.

Diet:

A healthy diet rich in calcium and phosphorus is the primary way to prevent and manage deficiencies in children. Here are some key dietary components:

Calcium-Rich Foods:

Milk and dairy products (yoghurt, cheese) - Fortified options can be a good choice.

Leafy green vegetables (broccoli, spinach, kale)

Calcium-fortified foods (cereals, plant-based milk)

Small, soft-boned fish (sardines with bones)

Tofu and tempeh (soy products)

Phosphorus-Rich Foods:

Meat, poultry, and fish

Eggs

Dairy products (milk, cheese, yoghurt)

Whole grains (oats, brown rice)

Nuts and seeds (almonds, sunflower seeds)

Beans and lentils

Lifestyle:

Vitamin D: Ensure adequate vitamin D intake, as it helps the body absorb calcium. Sunlight exposure (with sun protection) or supplements can be helpful.

Physical Activity: Regular weight-bearing exercises like walking, running, or jumping can promote bone development.

Limit sugary drinks and processed foods: These can hinder calcium absorption and contribute to unhealthy eating habits.

Additional Considerations:

Age-Appropriate Portions: Children have different dietary needs based on their age. Consult a paediatrician or registered dietitian for guidance on portion sizes specific to your child's needs.

Food Allergies/Intolerances: If your child has allergies or intolerances to certain foods (e.g., lactose intolerance), discuss alternative calcium and phosphorus sources with your paediatrician.

Supplements: In some cases, a paediatrician might recommend calcium-phosphorus supplements such as Nefrosave Keto-DS Tablet to address deficiencies, especially if dietary changes alone are insufficient.

Habit Forming

No

Therapeutic Class

NUTRITIONAL SUPPLEMENT
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Alcohol

Not applicable

It is intended for Children.

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Pregnancy

Not applicable

It is intended for Children.

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Breast Feeding

Not applicable

It is intended for Children.

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Driving

Not applicable

It is intended for Children.

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Liver

Safe if suggested

Please inform your doctor if your child has liver disease or impairment. Your doctor will weigh the benefits and potential risks before prescribing Nefrosave Keto-DS Tablet .

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Kidney

Safe if suggested

Please inform your doctor if your child has kidney disease or impairment. Your doctor will weigh the benefits and potential risks before prescribing Nefrosave Keto-DS Tablet .

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Children

Safe

Nefrosave Keto-DS Tablet can be used safely. The doctor will decide the dose of this medicine based on your child's age, body weight, and condition.

Have a query?

FAQs

Nefrosave Keto-DS Tablet is a nutritional supplement specifically designed for growing children. It provides a balanced combination of calcium and phosphorus, essential minerals for strong bones and teeth development.

1. Supports healthy bone and teeth development: The right ratio of calcium and phosphorus (2:1) in Nefrosave Keto-DS Tablet promotes optimal calcium absorption for building strong bones and teeth in children. 2. Prevents deficiencies: Nefrosave Keto-DS Tablet helps address deficiencies in calcium and phosphorus that can occur due to a lack of milk, leafy green vegetables, or an unbalanced diet. 3. May prevent rickets: Phosphorus deficiency can lead to rickets, a condition causing soft bones. Nefrosave Keto-DS Tablet helps prevent this by providing adequate phosphorus. 4. Enhanced absorption: Vitamin D3, magnesium, and zinc in Nefrosave Keto-DS Tablet further enhance the absorption and utilization of calcium for better bone health.

Nefrosave Keto-DS Tablet is generally well-tolerated. However, some mild digestive issues like constipation or stomach upset might occur. Taking the supplement with food can help minimize these.

Nefrosave Keto-DS is a dietary supplement used to manage chronic kidney disease (CKD) when combined with a low-protein diet.

It contains alpha-ketoanalogues, which are modified amino acids that provide essential nutrients without increasing the workload on the kidneys.

The time it takes to see results varies from person to person. Regular monitoring of kidney function is essential.

No, Nefrosave Keto-DS Tablet may not be suitable for all patients with kidney problems. The appropriateness of Nefrosave Keto-DS depends on the stage of CKD, overall health, and other medical conditions.

High blood pressure, diabetes, high cholesterol, kidney infections, kidney inflammation, recurring kidney stones, an enlarged prostate, and long-term, frequent use of certain medicines such as lithium and nonsteroidal anti-inflammatory drugs (NSAIDs) are common causes of CKD.

There are usually no symptoms of kidney disease in the early stages. However, in the advanced stage, symptoms may include tiredness, swollen ankles, feet or hands, shortness of breath, feeling sick, and blood in the urine at a more advanced stage.

Country of origin

India

Manufacturer/Marketer address

#1, Fourrts Avenue, Annai Indira Nagar, Okkiyam Thoraipakkam, Chennai, India.
Other Info - NEF0129

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