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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Nebigold-AM Tablet is used to treat high blood pressure. It contains Amlodipine and Nebivolol, which relaxes and widens the blood vessels making it easier for the heart to pump blood to all parts of the body. This lowers blood pressure and helps in reducing the risk of stroke, heart attack, other heart problems, or kidney problems in the future. It may cause side effects such as headaches, feeling exhausted, cold extremities, ankle swelling, slow heart rate, constipation, tiredness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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About Nebigold-AM Tablet

Nebigold-AM Tablet is a combination of blood pressure-lowering medicine, primarily used to treat high blood pressure. Nebigold-AM Tablet contains Amlodipine (calcium channel blocker) and Nebivolol (beta-blocker) which collectively lower blood pressure. Hypertension or high blood pressure is a chronic condition in which the force exerted by the blood against the artery wall is high. As a result, it leads to heart diseases, irregular heartbeat, and other complications.

Nebigold-AM Tablet contains Amlodipine (calcium channel blocker) and Nebivolol (beta-blocker),  primarily used to treat high blood pressure. Amlodipine works by relaxing the blood vessels. Nebivolol acts by relaxing and widening the blood vessels making it easier for the heart to pump blood to all parts of the body. This lowers your blood pressure and helps in reducing your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective.

Take Nebigold-AM Tablet as prescribed by your doctor. You are advised to take Nebigold-AM Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. Preferably take it after a meal to avoid an upset stomach. In some cases, you may experience headaches, feeling exhausted, cold extremities, ankle swelling, slow heart rate, constipation, tiredness. Most of these side effects of Nebigold-AM Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.  

It is advisable to drink plenty of fluids while taking this medicine to overcome muscle weakness, dry mouth, and extreme thirst. Do not take grapefruit or grapefruit juices with Nebigold-AM Tablet as it can increase the concentration of Nebigold-AM Tablet and worsen its side effects. Please inform your doctor if you have had an allergic reaction to Nebigold-AM Tablet, are pregnant or planning to get pregnant, are breastfeeding, have liver disease or kidney disease, heart failure, diabetes, a heart valve problem, or heart attack. Reducing the amount of table salt (sodium chloride) in your food often relieves the swelling of the body. Nebigold-AM Tablet is prescribed to adults and children more than six years of age.

Uses of Nebigold-AM Tablet

Treatment of Hypertension (high blood pressure).

Directions for Use

Swallow Nebigold-AM Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Nebigold-AM Tablet is a combination of blood pressure-lowering medicine, contains Amlodipine (calcium channel blocker) and Nebivolol (beta-blocker), primarily used to treat high blood pressure. Amlodipine works by relaxing the blood vessels. Nebivolol acts by relaxing and widening the blood vessels, making it easier for the heart to pump blood to all parts of the body. This lowers your blood pressure and reduces your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective.

How Nebigold-AM Tablet Works

Nebigold-AM Tablet contains Amlodipine (calcium channel blocker) and Nebivolol (beta-blocker),  primarily used to treat high blood pressure. Amlodipine works by relaxing the blood vessels. Nebivolol acts by relaxing and widening the blood vessels making it easier for the heart to pump blood to all parts of the body. This lowers your blood pressure and helps in reducing your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Nebigold-AM Tablet

  • Headaches
  • Feeling exhausted 
  • Cold extremities
  • Ankle swelling
  • Slow heart rate
  • Constipation
  • Tiredness

What if I have taken an overdose of Nebigold-AM Tablet

Do not take more than the prescribed dose of Nebigold-AM Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Don't stop taking Nebigold-AM Tablet without talking to your doctor first. Stopping Nebigold-AM Tablet abruptly may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will lower your dose gradually over a period of time to help prevent these symptoms. You should not use Nebigold-AM Tablet if you have a very slow heartbeat, asthma, serious heart condition (sick sinus syndrome), or any heart blockage. It should not be given to children less than 12 years of age. Before taking Nebigold-AM Tablet you should tell the doctor if you have any muscle disorder (myasthenia gravis, rhabdomyolysis), breathing problem (COPD, bronchitis, emphysema), low blood sugar level (hypoglycemia), low blood pressure (hypotension), depression, previous heart failure, liver/kidney disease, thyroid hormone disorder, adrenal gland cancer, or problems with circulation (Raynaud’s syndrome).

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
AmlodipineMitotane
Severe

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Nebigold-AM Tablet:
Using Nebigold-AM Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Nebigold-AM Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
AmlodipineMitotane
Severe
How does the drug interact with Nebigold-AM Tablet:
Using Nebigold-AM Tablet and mitotane together may drastically lower Nebigold-AM Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Nebigold-AM Tablet with mitotane can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineLemborexant
Severe
How does the drug interact with Nebigold-AM Tablet:
Coadministration of lemborexant and Nebigold-AM Tablet may increase the blood levels of lemborexant.

How to manage the interaction:
Although co-administration of Nebigold-AM Tablet with Lemborexant can result in an interaction, it can be taken if a doctor has advised it. However, consult your doctor if you experience abnormal sleep patterns, worsening of depression, changes in heartbeat, or headache. Do not discontinue any medications without consulting a doctor.
AmlodipinePrimidone
Severe
How does the drug interact with Nebigold-AM Tablet:
Using Nebigold-AM Tablet and primidone together may lower Nebigold-AM Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Nebigold-AM Tablet with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineRifampicin
Severe
How does the drug interact with Nebigold-AM Tablet:
Coadministration of Nebigold-AM Tablet and rifampicin together may lower Nebigold-AM Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Nebigold-AM Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AmlodipineTizanidine
Severe
How does the drug interact with Nebigold-AM Tablet:
Co-administration of Tizanidine and Nebigold-AM Tablet can increase the risk or severity of developing side effects like low blood pressure.

How to manage the interaction:
Although co-administration of Nebigold-AM Tablet with tizanidine can result in an interaction, it can be taken when a doctor has advised it. However, if you experience headache, dizziness, palpitations, or irregular heart rate while taking these drugs, contact the doctor immediately. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not discontinue any medications without consulting the doctor.
AmlodipineIdelalisib
Severe
How does the drug interact with Nebigold-AM Tablet:
Coadministration of Nebigold-AM Tablet and Idelalisib may raise Nebigold-AM Tablet levels in the blood this may lead to serious side effects (irregular heart rhythm, fluid retention, swelling, heart failure, and abnormally low blood pressure).

How to manage the interaction:
Although taking Nebigold-AM Tablet with idelalisib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness or fainting, sudden, unexplained weight gain, swelling of the hands, ankles, or feet, chest discomfort, or trouble breathing while taking these drugs, consult the doctor. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not stop using any medications without a doctor's advice.
AmlodipineRifabutin
Severe
How does the drug interact with Nebigold-AM Tablet:
Using Nebigold-AM Tablet and rifabutin together may lower Nebigold-AM Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Nebigold-AM Tablet with rifabutin, but it can be taken if a doctor has advised it. Consult the doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
AmlodipineSirolimus
Severe
How does the drug interact with Nebigold-AM Tablet:
Co-administration of Nebigold-AM Tablet can make Sirolimus may increase the risk of angioedema (a condition associated with swelling of the face, eyes, lips, tongue, throat, and occasionally also the hands and feet).

How to manage the interaction:
There may be a possibility of interaction between Nebigold-AM Tablet and Sirolimus, but it can be taken if prescribed by a doctor. However, consult the doctor if you notice any swelling of the face, eyes, lips, tongue, throat, hands and feet or have trouble breathing or swallowing. Do not stop using any medications without a doctor's advice.
AmlodipineItraconazole
Severe
How does the drug interact with Nebigold-AM Tablet:
Coadministration of Nebigold-AM Tablet with itraconazole may significantly raise the blood levels and effects of Nebigold-AM Tablet.

How to manage the interaction:
Nebigold-AM Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing, dizziness or fainting, swelling of the hands, ankles, or feet, or any other of these symptoms. Without consulting a doctor, never stop taking any medication.

Drug-Food Interactions

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NEBIVOLOL-5MG+AMLODIPINE-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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NEBIVOLOL-5MG+AMLODIPINE-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice

How to manage the interaction:
Consumption of grapefruit and grapefruit juice with Nebigold-AM Tablet the levels of Nebigold-AM Tablet in your bloodstream may drop. Avoid consuming a lot of grapefruit juice and grapefruit when using Nebigold-AM Tablet, instead, take it with water. As a result, your body will absorb the drug more easily.

Diet & Lifestyle Advise

  • Keep your weight under control with BMI (Body Mass Index) 19.5-24.9.

  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • If you are taking alcohol, then only one serving for women and two servings is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
  • Try to include heart-healthy omega-3 fatty acids containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil can help in lowering your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Nebigold-AM Tablet Substitute

Substitutes safety advice
  • Nebi-AM Tablet 10's

    13.05per tablet
  • Nodon AM Tablet 15's

    18.72per tablet
  • Nebilong-AM Tablet 15's

    12.24per tablet
  • Nebula AM Tablet 10's

    22.55per tablet
  • Nebiqol-AM-5 Tablet 10's

    11.34per tablet
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Alcohol

Caution

You are recommended not to consume alcohol along with Nebigold-AM Tablet to avoid unpleasant side-effects.

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Pregnancy

Caution

It is advised to consult your doctor if you plan to conceive or are already pregnant before starting Nebigold-AM Tablet.

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Breast Feeding

Caution

Please consult your doctor before taking Nebigold-AM Tablet if you are breastfeeding; your doctor will prescribe you Nebigold-AM Tablet only if the benefits outweigh the risks.

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Driving

Caution

Nebigold-AM Tablet may cause dizziness and weakness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Nebigold-AM Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Nebigold-AM Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Nebigold-AM Tablet should not be used by children, as the efficacy and safety have not been established.

FAQs

Nebigold-AM Tablet is used to treat hypertension (high blood pressure).
Nebigold-AM Tablet contains Amlodipine (calcium channel blocker) and Nebivolol (beta-blocker); primarily used to treat high blood pressure. Amlodipine works by relaxing the blood vessels. Nebivolol acts by relaxing and widening the blood vessels making it easier for the heart to pump blood to all parts of the body. This lowers your blood pressure and helps in reducing your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future.
Your doctor may probably tell you to stop taking Nebigold-AM Tablet as it lowers blood pressure (hypotension) when combined with general anaesthesia before surgery. So, please inform your doctor before surgery if you are taking Nebigold-AM Tablet.
Yes, Nebigold-AM Tablet is known to cause ankle swelling. Please try to keep your feet up when sitting for long hours. If the problem persists still, consult your doctor and do as advised.
If you have diabetes, you should monitor your blood glucose levels often as Nebigold-AM Tablet might mask hypoglycemia symptoms (low glucose levels). However, please consult your doctor before taking Nebigold-AM Tablet if you have diabetes.
If you have hyperthyroidism (overactive thyroid), you should monitor your condition regularly as Nebigold-AM Tablet might mask hyperthyroidism symptoms such as abnormally fast heart rate. However, please consult your doctor before taking Nebigold-AM Tablet if you have hyperthyroidism.
Do not overdose on Nebigold-AM Tablet or any medicine, which could lead to very unpleasant side effects. Take Nebigold-AM Tablet only as prescribed by your doctor. An overdose of Nebigold-AM Tablet can cause a very slow heartbeat, low blood pressure, breathlessness, and acute heart failure. Rush to your nearest doctor as early as possible if you have overdosed on Nebigold-AM Tablet.
You should take Nebigold-AM Tablet as advised by your doctor. But take it at the same time every day for consistency. Swallow it as whole with a glass of water. Do not break, crush or chew it.
If you miss a dose of Nebigold-AM Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the risk of side effects.
Nebigold-AM Tablet may cause side effects such as headache, ankle swelling, slow heart rate, tiredness, constipation or cold extremities (cold hands and feet). If these side effects persist or worsen, please consult your doctor.
You are recommended to take your doctor’s advice before taking Nebigold-AM Tablet if you are pregnant or breastfeeding.
No, do not stop taking Nebigold-AM Tablet even if you feel better as discontinuing Nebigold-AM Tablet suddenly may raise your blood pressure. Therefore, please consult your doctor before making any changes to your dosage schedule.

Country of origin

India

Manufacturer/Marketer address

Kh No - 223, Plot No - 16, Mohanpura-Mohammadpur, South Civil Lines, Distt-Haridwar, Roorkee, Uttarakhand - 247667, India
Other Info - NE26831

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