Nebicard-V Tablet belongs to the group of medications called ‘antihypertensives’ primarily used in the treatment of hypertension. Hypertension or high blood pressure is a chronic (long-term) condition in which blood pressure is elevated persistently at higher than normal levels. If left untreated, this condition can increase the risk of heart-related diseases like heart attack, heart failure, stroke, irregular heartbeat and other complications.

Nebicard-V Tablet contains Nebivolol and Valsartan. Nebivolol is a beta-blocker. It works specifically on the heart to reduce heart rate and lower blood pressure making it easier for the heart to pump blood to all parts of the body. Valsartan is an angiotensin-II receptor blocker (ARB). Angiotensin narrows the blood vessels increasing the blood pressure, therefore, blocking angiotensin can result in widening of the narrowed blood vessels. Together, Nebicard-V Tablet can effectively treat hypertension or high blood pressure. 

You should take this medicine exactly as prescribed by the doctor. The common side-effects of Nebicard-V Tablet are nausea, vomiting, bradycardia (slow heartbeats), dizziness, hypotension (low blood pressure), hyperkalemia (increased potassium levels in the blood) and elevated liver enzymes. Inform your doctor immediately if any of these side-effects persist or get worse.

It is not recommended to take Nebicard-V Tablet if you are allergic to any contents of it. It is also not recommended for patients with ‘sick sinus syndrome’ (unless you have a pacemaker), heart block, severe heart failure, severe liver disease and history of bradycardia (slow heartbeat) that have resulted in fainting. Nebicard-V Tablet should not be used in children and adolescents below 18 years of age, pregnant women and breastfeeding mothers. It should be used with caution in elderly people. Avoid alcohol consumption as it may increase the risk of side-effects. Nebicard-V Tablet may cause dizziness, so avoid driving or operating heavy machinery if you feel dizzy.

Nebicard-V Tablet contains ‘Nebivolol’ and ‘Valsartan’ which is a fixed-dose combination used to treat hypertension in adults. It works by lowering the body’s production of substances that could increase heart rate and also widens narrowed blood vessels. It allows the blood to flow more smoothly in the blood vessels. It shows greater efficacy and tolerability when compared to monotherapies. It helps to reduce serious complications of hypertension such as heart attack, stroke and end-stage kidney disease.

• Nausea
• Vomiting
• Bradycardia (slow heartbeat)
• Dizziness
• Hypotension (low blood pressure)
• Hyperkalemia (increase in potassium levels in the blood)
• Elevated liver enzymes
• Constipation
• Altered sensation of extremities

Before taking Nebicard-V Tablet , inform your doctor if you have decreased potassium levels in the blood, kidney disease or on dialysis, liver disease, heart disease, hyperthyroidism (overactive thyroid), are on a low-salt diet, and dehydration (due to vomiting or diarrhea).  If you notice dizziness, confusion, weakness and fainting while using Nebicard-V Tablet , inform your doctor immediately. Do not exercise heavily or avoid hot weather as excess sweating may lead to dehydration, thereby resulting in low blood pressure and electrolyte imbalances. Severe nausea, vomiting and diarrhea may also lead to dehydration resulting in low blood pressure. Inform your doctor immediately if you experience chest pain, extreme tiredness, irregular heartbeat or difficulty breathing, as Nebicard-V Tablet may worsen symptoms of heart failure in some patients. If you notice stomach pain, difficulty breathing, numbness in the hands, feet or lips, weakness in the legs and irregular heartbeat, inform your doctor immediately. These symptoms can be a sign of hyperkalemia (high potassium levels in the blood).

Drug-Drug Interactions: Nebicard-V Tablet may interact with blood pressure-lowering medication (aliskiren), water pills, other blood pressure-lowering medications, medicine that suppresses the immune system (cyclosporine),  antidepressants (fluoxetine and lithium), antitubercular agent (rifampin), a medicine used to treat HIV (ritonavir), potassium supplements, pain killers (aspirin, ibuprofen, naproxen, celecoxib, diclofenac, etc.).

Drug-Food Interactions: Do not take alcohol as it can further lower blood pressure and may increase the risk of side effects.

Drug-Disease Interactions: Nebicard-V Tablet should not be used in patients with severe heart problems such as ‘sick sinus syndrome’ (unless you have a pacemaker) or heart block, severe heart failure, severe liver disease and history of bradycardia (slow heartbeat) that have resulted in fainting.

• ALISKIREN
• CYCLOSPORINE
• FLUOXETINE
• LITHIUM
• RIFAMPIN
• RITONAVIR
• ASPIRIN
• IBUPROFEN
• NAPROXEN
• CELECOXIB
• DICLOFENAC

• Keep your weight under control with a BMI of 19.5-24.9.
• Do regular physical activity or exercise for at least 150 minutes per week or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
• Option for a diet rich in whole grains, fruits, veggies and low-fat dairy products.
• Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
• If you are taking alcohol then only one serving for women and two servings for men is advisable.
• Quitting smoking is the best strategy to lower the risk of heart disease.
• Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
• Monitor your blood pressure daily and if there is too much fluctuation then immediately contact your doctor.
• Try to include heart-healthy omega 3 fatty acid containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil and coconut oil can help in lowering your elevated blood pressure.

• Do not take potassium supplements, a potassium-rich diet, or salt substitutes while using this medicine as it may increase potassium levels in the blood.
• Your doctor may also monitor blood pressure, kidney function and potassium levels while taking this medicine.
• Nebicard-V Tablet may cause orthostatic hypotension, so do not stand up too fast when rising from a sitting or lying position.
• Do not stop taking this medication suddenly, as the abrupt stopping of this medicine may lead to chest pain or heart attack.

Hypertension: It is a chronic (long-term) condition in which blood pressure is elevated persistently at higher than normal levels. It occurs when the blood’s force against the wall of blood vessels is too high. This condition can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes damage to the brain, kidneys and eyes. The risk of high blood pressure complications increases with the following: obesity, smoking, diabetes, alcohol intake, lack of physical inactivity, stress and kidney diseases.