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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Natclovir 250 Capsule is an antiviral drug used to treat viral infections. It plays a vital role in treating Cytomegalovirus infection in immunosuppressed people (having HIV/AIDS) or who underwent bone marrow or organ transplantation. It contains Ganciclovir, which prevents the multiplication of virus in human cells and decreases viral overload and stops the production of new viruses.

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Whats That

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Composition :

GANCICLOVIR-250MG

Manufacturer/Marketer :

Natco Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Natclovir 250 Capsule

Natclovir 250 Capsule belongs to a class of drugs known as 'antiviral,'  which is used to treat viral infections. It plays a vital role in treating Cytomegalovirus infection in immunosuppressed people (having HIV/AIDS) or who underwent bone marrow or organ transplantation. Cytomegalovirus infection is a common herpes virus infection with no symptoms or symptoms like fever and fatigue. Severe infection may affect the eyes, brain, or other internal organs.

Natclovir 250 Capsule contains Ganciclovir, an antiviral medication. It works by preventing the multiplication of viruses in human cells by acting on their DNA results in a decrease viral overload and the production of new viruses. Hence, this helps in clearing up the infection.

Take Natclovir 250 Capsule as prescribed by your doctor. It can be taken with or without food. You are advised to take Natclovir 250 Capsule for as long as your doctor has prescribed it for you, depending upon your medical condition. In some cases, you may experience nausea, headache, dizziness, fever, vomiting, diarrhoea, increased liver enzymes, and stomach pain. Most of these side effects of Natclovir 250 Capsule are temporary, do not require medical attention, and gradually subside over time. However, if the side effects are persistent, reach out to your doctor immediately.

Do not take Natclovir 250 Capsule if you are allergic to it, aciclovir or any of its ingredients. Never encourage self-medication or suggest your medicine to someone else, even if the symptoms occur similarly. Check with your doctor if you're pregnant, currently breastfeeding or taking any other prescribed or non-prescribed medicines. Use protection while having sexual intercourse to avoid the transfer of infection to your partner. If you have a weak immune system, please inform your doctor before taking Natclovir 250 Capsule , as a dose adjustment may be required.

Uses of Natclovir 250 Capsule

Treatment of cytomegalovirus infection

Directions for Use

Take Natclovir 250 Capsule with or without food or as directed by your physician. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Natclovir 250 Capsule contains Ganciclovir, which belongs to a class of drugs known as antiviral medicines. It is used to treat viral infections. It plays a vital role in treating Cytomegalovirus Infection in Immunosuppressed people who have undergone bone marrow or organ transplantation. In addition to this, it also reduces the risk of blindness in people with serious eye infections (CMV retinitis). It works by preventing the multiplication of viruses in human cells by acting on their DNA, resulting in decreased viral overload and new virus production. Hence, this helps in clearing up the infection.

How Natclovir 250 Capsule Works

Natclovir 250 Capsule contains Ganciclovir, an antiviral medication. It works by preventing the multiplication of viruses in human cells by acting on their DNA results in a decrease viral overload and the production of new viruses. Hence, this helps in clearing up the infection.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Natclovir 250 Capsule

  • Headache
  • Dizziness
  • Nausea
  • Fever
  • Vomiting
  • Diarrhea
  • Increased liver enzymes
  • Stomach pain

What if I have taken an overdose of Natclovir 250 Capsule

Do not take more than the prescribed dose of Natclovir 250 Capsule as it may cause overdose. The symptoms of overdose include fits or shaking, blood in urine, diarrhoea, stomach pain, nausea, liver or kidney problems and changes in blood cells counts. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Natclovir 250 Capsule if you are allergic to Natclovir 250 Capsule  or any of its ingredients. Inform your doctor if you have or have ever had anaemia (red blood cells do not bring enough oxygen to all parts of the body), neutropenia (less than a normal number of white blood cells), thrombocytopenia (less than a normal number of platelets) or other blood or bleeding problems as Natclovir 250 Capsule may lower the blood cell count or if you have received or are receiving radiation (X-ray) therapy. If you experience any of the following symptoms, call your doctor immediately: excessive tiredness, pale skin, headache, dizziness, confusion, fast heartbeat, difficulty falling asleep or staying asleep, weakness, shortness of breath, unusual bleeding or bruising or sore throat, fever, chills, cough or other signs of infection.

Drug-Drug Interactions

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GanciclovirCidofovir
Critical
GanciclovirDeferiprone
Severe

Drug-Drug Interactions

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GanciclovirCidofovir
Critical
How does the drug interact with Natclovir 250 Capsule:
Coadministration of cidofovir with Natclovir 250 Capsule can increase the risk of kidney problems.

How to manage the interaction:
Although there is a interaction between Natclovir 250 Capsule and Cidofovir hence it is not recommended to be taken together, but it can be taken only if advised by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
GanciclovirDeferiprone
Severe
How does the drug interact with Natclovir 250 Capsule:
Natclovir 250 Capsule can cause higher levels of Deferiprone in the blood by reducing its excretion rate. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Natclovir 250 Capsule and Deferiprone together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you're having any of these symptoms - like a sore throat, fever, or muscle aches - it's important to let a doctor know right away. Do not stop using any medications without a doctor's advice.
GanciclovirInfliximab
Severe
How does the drug interact with Natclovir 250 Capsule:
Combining Infliximab with Natclovir 250 Capsule can increase the risk or severity of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Natclovir 250 Capsule and Infliximab, but it can be taken if prescribed by a doctor. If you have any of these symptom's fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate contact your doctor immediately. Don't hesitate to reach out to a doctor if you experience any of these. Do not stop using any medications without a doctor's advice.
GanciclovirZidovudine
Severe
How does the drug interact with Natclovir 250 Capsule:
Using zidovudine together with Natclovir 250 Capsule may increase the risk of side effects affecting the blood leading to decreased levels of blood cells.

How to manage the interaction:
Taking Natclovir 250 Capsule with zidovudine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of fever, chills, sore throat, rashes, tiredness, headaches, irritation, confusion, edema, fatigue, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
GanciclovirAdalimumab
Severe
How does the drug interact with Natclovir 250 Capsule:
Using Natclovir 250 Capsule together with adalimumab may increase the risk of serious infections.

How to manage the interaction:
Taking Natclovir 250 Capsule with adalimumab together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GanciclovirCertolizumab
Severe
How does the drug interact with Natclovir 250 Capsule:
Using Natclovir 250 Capsule together with certolizumab may increase the risk of serious infections.

How to manage the interaction:
Taking Natclovir 250 Capsule with certolizumab together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GanciclovirGolimumab
Severe
How does the drug interact with Natclovir 250 Capsule:
Using Natclovir 250 Capsule together with golimumab may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Natclovir 250 Capsule and Golimumab, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms like fever, chills, diarrhea, a sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee contact a doctor immediately. Do not stop using any medications without a doctor's advice.
GanciclovirTenofovir disoproxil
Severe
How does the drug interact with Natclovir 250 Capsule:
coadministration of Tenofovir disoproxil with Natclovir 250 Capsule can increase the risk or severity of side effects like kidney damage.

How to manage the interaction:
Although taking Natclovir 250 Capsule and Tenofovir disoproxil together can cause an interaction, it can be taken if your doctor has suggested it. If you have symptoms like feeling sick, not wanting to eat, gaining or losing weight suddenly, holding onto fluids, swelling, trouble breathing, bone or muscle pain, feeling weak or dizzy, feeling confused, or having an irregular heartbeat -contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
GanciclovirMaribavir
Severe
How does the drug interact with Natclovir 250 Capsule:
Coadministration of Natclovir 250 Capsule with Maribavir may alter the effectiveness of both these medications. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Maribavir and Natclovir 250 Capsule together can possibly result in an interaction; it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
GanciclovirClozapine
Severe
How does the drug interact with Natclovir 250 Capsule:
Clozapine can cause higher levels of Natclovir 250 Capsule in the blood by reducing its excretion rate. This can increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Natclovir 250 Capsule and Clozapine, you can take these medicines together if prescribed by a doctor. If you're having any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, weight loss, or pain, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid alcoholic beverages with Natclovir 250 Capsule as it can make you dehydrated and may affect your sleep.
  • Try to include heart-healthy omega 3 fatty acid containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil and coconut oil.
  • Include turmeric or yellow mustard in your diet to avoid constipation caused by antiviral drugs and increase the intake of fluids to stay hydrated.
  • Try to reduce emotional and physical stress by spending time with family or whatever makes you happy.
  • Eat a healthy and balanced diet and make sure you sleep at least 8 hours a day for a speedy recovery.
  • If you are going in strong sunlight, please wear a lip balm SPF 15 or higher and Natclovir 250 Capsule makes you sensitive to UV and sunlight.

Habit Forming

No

Therapeutic Class

ANTIVIRALS

Natclovir 250 Capsule Substitute

Substitutes safety advice
  • Natclovir 250 Capsule 30's

    by Others

    84.43per tablet
  • Gavir 250 Capsule 8's

    by AYUR

    129.71per tablet
  • Vitravene 250mg Capsule

    by Others

    132.75per tablet
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Alcohol

Caution

Alcohol is not known to cause any unpleasant side effects if taken along with Natclovir 250 Capsule . But intake of alcohol with Natclovir 250 Capsule may damage your liver. So intake of alcohol should be avoided with Natclovir 250 Capsule .

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Pregnancy

Caution

Natclovir 250 Capsule is a pregnancy Category C medicine. It is not known whether Natclovir 250 Capsule will affect pregnant women or fetus or not. Hence, the intake of Natclovir 250 Capsule should be only if prescribed and under medical supervision.

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Breast Feeding

Caution

Natclovir 250 Capsule is a pregnancy Category C medicine. It is not known whether Natclovir 250 Capsule will pass through the milk in breastfeeding women or not. Hence, Natclovir 250 Capsule should only be taken if prescribed by a doctor and under medical supervision.

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Driving

Unsafe

Natclovir 250 Capsule can affect alertness and coordination. So, operating machinery which requires concentration should be avoided.

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Liver

Caution

Natclovir 250 Capsule to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Natclovir 250 Capsule to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Natclovir 250 Capsule is not recommended for children below 12 years as its safety and efficacy are not established.

FAQs

Natclovir 250 Capsule is used to treat viral infections. It plays a vital role in treating Cytomegalovirus infection in immunosuppressed people (having HIV/AIDS) or who underwent bone marrow or organ transplantation.

Natclovir 250 Capsule belongs to a class of drugs known as 'antiviral',  containing Ganciclovir which is used to treat viral infections. It works by preventing the multiplication of viruses in human cells by acting on its DNA results in decrease viral overload and production of new viruses. Hence, this helps in clearing up the infection.

The most common side effects of Natclovir 250 Capsule are headaches, dizziness, nausea, fever, vomiting, diarrhoea, and stomach pain. Most of these side effects of Natclovir 250 Capsule are temporary, do not require medical attention, and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

No, you should not stop taking Natclovir 250 Capsule without consulting the doctor even if you feel better. The symptoms may improve, but the infection may not be completely cured. Therefore, it is advised to continue the treatment in dose and duration prescribed for the best treatment.

Natclovir 250 Capsule may affect fertility. It may temporarily or permanently stop men from producing sperm and reduce fertility in women. So, if you are planning a baby, inform your doctor before taking Natclovir 250 Capsule . Also, wear a condom during sexual intercourse to avoid the transfer of infection to the female counterpart.

No, Natclovir 250 Capsule should be taken in the dose and duration as advised by the doctor. If you take it in more than the recommended dose, it might cause unpleasant side effects. If you think your symptoms are not improving, please consult your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Other Info - NAT0052

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