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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 30, 2024 | 3:21 PM IST
NAC PLUS TABLET is used to relieve pain associated with osteoarthritis, sprain, strain, rheumatoid arthritis and ankylosing spondylitis. It contains Diclofenac and Acetaminophen which work by inhibiting chemical messengers that cause pain and inflammation. This medicine may sometimes cause side effects such as stomach upset, dizziness, light-headedness, malaise, nausea, vomiting and rash. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer

Systopic Laboratories Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About NAC PLUS TABLET

NAC PLUS TABLET belongs to a class of medications known as a non-steroidal anti-inflammatory drug (NSAID) or pain killer. NAC PLUS TABLET is primarily indicated for relieving pain associated with bones and muscles like osteoarthritis (joints pain), sprains and strains of muscles, rheumatoid arthritis (pain, swelling, and stiffness of joints) and ankylosing spondylitis (inflammation of the spine). This medicine also provides relief in pain associated with back pain, toothache,  rheumatoid arthritis, painful menses, mild migraine, etc. Pain is an uncomfortable feeling in the body that can range from annoying to severe.

NAC PLUS TABLET contains Diclofenac (analgesic) and Acetaminophen (fever reducer/mild analgesic) effective against painful musculoskeletal pain, joint pain, and skeletal muscle spasms. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX) which causes pain and swelling at the injured or damaged tissue site. On the other hand, Acetaminophen acts as a mild analgesic (mild pain reducer) and antipyretic (fever reducer), which enhances the pain relief action of Diclofenac. Both medicines in combination work well to provide relief pain in different conditions.

Take NAC PLUS TABLET as prescribed by your doctor. You are advised to take NAC PLUS TABLET for as long as your doctor has prescribed it for you depending on your medical condition. Like all medicines, NAC PLUS TABLET may cause common side effects like stomach upset, dizziness, light-headedness, malaise, nausea, vomiting and liver dysfunction (hepatitis), pruritis (itchy skin), rash, although not everybody gets them. Stop taking this medicine if you experience symptoms like the tightness of the chest, breathing difficulties, fever, skin rashes, increased heart rate and or in case of any signs of hypersensitivity.

Do not take NAC PLUS TABLET if you are allergic to painkillers like aspirin, acetaminophen, naproxen or diclofenac. It is not recommended for use in children less than 14 years of age, people with liver disease, heart disease or gastric ulcers/bleeding problems. NAC PLUS TABLET may be associated with a small increase in the risk of heart attack (myocardial infarction). Pregnant women should not take this medicine during their last trimester of pregnancy. NAC PLUS TABLET is excreted in the breast milk so the nursing mother should contact the doctor before its usage. Avoid consumption of alcohol as it may damage your liver and cause even more side effects from taking this drug.

Uses of NAC PLUS TABLET

Treatment of Musculoskeletal pain, Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis, Rheumatoid arthritis, Painful menses, Mild migraine, etc.

Medicinal Benefits

NAC PLUS TABLET is a combination medicine used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, tooth pain, bone and joint pain, headache, swelling, period pain, ear pain, migraine, fever,  sore throat, nose pain, etc.  By reducing the pain, NAC PLUS TABLET helps you to do normal daily activities of the day. Diclofenac present in NAC PLUS TABLET works by reducing the chemical messenger that is responsible for pain and inflammation in the body. While Acetaminophen works by blocking chemical messenger that sends pain signals to the brain. This medicine also reduces fever by regulating body temperature. Both medicines in combination increase the pain threshold and blood flow across the skin and provide relief in various painful conditions.

Directions for Use

Swallow NAC PLUS TABLET as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of NAC PLUS TABLET

  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhoea
  • Indigestion
  • Headache

Drug Warnings

Do not take NAC PLUS TABLET if you have/had severe heart problems, stomach ulcer or perforation, bleeding problems such as bleeding from the stomach, intestine or brain, have undergone any heart bypass surgery, have had any heart attack, blood circulation problems or inflammation of intestines.  Patients with asthma, prolonged bleeding time, wheezing (whistling sound during breath) and blocked airways (bronchospasm) should avoid using NAC PLUS TABLET. Consult your doctor if your symptoms of pain, inflammation and fever do not disappear even after ten days. If you are using topical form NAC PLUS TABLET you should avoid direct exposure to the sunlight as sunburn or photosensitivity might occur. Keep your doctor informed about your health condition and medicines to rule out any side-effects. Avoid simultaneous consumption of other painkillers or cough and cold medicines with this NAC PLUS TABLET as it may lead to overdose.  Stop taking NAC PLUS TABLET and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach such as blood in stools. Do not take any other NSAID's for pain relief along with NAC PLUS TABLET unless prescribed. 

Drug Interactions

Drug-Drug Interactions: NAC PLUS TABLET may have interaction with pain killers (aspirin, ibuprofen), immunosuppressant (cyclosporine, tacrolimus), anti-psychotic (lithium), cardiac glycoside (digoxin), blood thinner (warfarin), anti-rheumatoid (methotrexate), antacid (magnesium hydroxide), anti-fungal (ketoconazole, miconazole, fluconazole, voriconazole), anti-arrhythmic (amiodarone), anti-gout (sulphinpyrazole), anti-emetic (metoclopramide, domperidone), bile acid sequestrant (cholestyramine), anti-cancer (imatinib), antibiotic (chloramphenicol), anti-progestational steroid (mifepristone), anti-diabetics, diuretics, anti-hypertensives medicines.

Drug-Food Interactions: Avoid consumption of alcohol while taking NAC PLUS TABLET as it might cause increased dizziness and risk of stomach bleeding.

Drug-Disease Interactions: NAC PLUS TABLET may worsen the symptoms in people with stomach ulcer or perforation, bleeding problems, bypass surgery, heart attack, blood circulation problems, inflammation of intestines, anemia, heart, kidney and liver problems.
 

Drug-Drug Interactions Checker List

  • TACROLIMUS
  • CYCLOSPORINE
  • CHLORAMPHENICOL
  • MIFEPRESTONE
  • CHOLESTYRAMINE
  • DOMPERIDONE
  • IMATINIB
  • MAGNESIUM HYDROXIDE
  • KETOCONAZOLE
  • VORICONAZOLE
  • METOCLOPRAMIDE
  • SULFINPYRAZONE
  • AMIDODARONE
  • FLUCONAZOLE
  • MICONAZOLE
  • METHOTREXATE
  • WARFARIN
  • DIGOXIN
  • IBUPROFEN
  • LITHIUM
  • ASPIRIN

Habit Forming

No

Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes, instead, wear loose garments.
  • Rest well, get plenty of sleep.
  • To avoid developing pressure sores, change your position at least every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20 minutes.
  • Stay hydrated, drink plenty of water.

Special Advise

  • Prolonged use of NAC PLUS TABLET may increase the risk of heart diseases. So if you have any heart problems or have undergone any planned heart bypass surgery, please do not take NAC PLUS TABLET and consult a doctor. 
  • If you have had a gastrointestinal ulcer or bleeding problem, do not take NAC PLUS TABLET. 
  • NAC PLUS TABLET should not be given to the children less than 10 years of age. 
  • Close monitoring of infections as NAC PLUS TABLET may mask the signs and symptoms of infection.

Disease/Condition Glossary

Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp, it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). Pain can be considered a good thing as it helps us know that something is wrong in the body and thereby helps diagnose the condition. The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, and arthritis.

Osteoarthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation, and tenderness.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities, and loss of joint function. 

Ankylosing spondylitis: It causes pain and stiffness in the spine. The pain generally starts in the lower back and can spread to the neck, damaged joints, or other body parts. Ankylosing spondylitis includes decreased flexibility which usually leads to hunched-forward posture, pain, and back, and joints.

Migraine: A headache of varying intensity, often accompanied by nausea and sensitivity to light and sound.

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Alcohol

Unsafe

Avoid consumption of alcohol while taking NAC PLUS TABLET as it may increase drowsiness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Avoid taking NAC PLUS TABLET if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking NAC PLUS TABLET, your doctor will decide whether NAC PLUS TABLET can be taken by breastfeeding mothers or not.

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Driving

Caution

NAC PLUS TABLET may affect driving ability as it causes headaches, blurred vision, dizziness or drowsiness so do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

NAC PLUS TABLET is not recommended for children below 12 years of age without the doctor's consent. For children above 12 years, the dose needs to be adjusted and recommended by a child specialist only.

Country of origin

India

Manufacturer/Marketer address

Systopic Laboratories Pvt. Ltd., 101, Pragati Chambers, Commercial Complex, Ranjit Nagar, New Delhi-110008
Other Info - NAC0003

Author Details

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FAQs

NAC PLUS TABLET is used to relieve pain in conditions like osteoarthritis, sprains and strains of muscles, rheumatoid arthritis, ankylosing spondylitis, back pain, toothache, painful menses, and mild migraine.
NAC PLUS TABLET should not be taken as a long term medication as it may lead to stomach ulcers/bleeding and kidney problems. For best results of NAC PLUS TABLET, take it in doses and duration mentioned by your doctor.
NAC PLUS TABLET is not indicated for stomach pain. Also, If you have stomach pain post-ingestion it may be a sign of stomach ulcer or gastric bleeding. Do not take NAC PLUS TABLET in this condition. It is better to inform your doctor in case of stomach pain.
It is advised not to take NAC PLUS TABLET until prescribed by your doctor.
Yes, NAC PLUS TABLET is a short term medication and if you feel better you can stop taking NAC PLUS TABLET, but only after consulting your doctor.
NAC PLUS TABLET is a combination of two drugs, namely: Diclofenac, and Acetaminophen. Diclofenac and Acetaminophen work by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandin (PG). By blocking the COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain, fever and inflammation at the injured or damaged site.
NAC PLUS TABLET is used to reduce and relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Arthritis is the tenderness and swelling in the joints.
NAC PLUS TABLET should not be taken for longer durations unless prescribed by the doctor. If NAC PLUS TABLET has been prescribed for longer durations, regular monitoring of kidney function, liver function and blood count is advised, particularly in elderly patients.
Diarrhea might be a side-effect of NAC PLUS TABLET. Drink enough fluids and eat fiber rich food if you experience diarrhea. If you find blood in stools (tarry stools) or if you experience excess diarrhea consult your doctor. Do not take anti-diarrheal medicine on your own.
No, NAC PLUS TABLET is not used to treat migraine, it is used to decrease pain caused by mild migraine.
Before taking NAC PLUS TABLET, consult your doctor and share your medical history. Follow the recommended dosage and be mindful of potential interactions with other medications or health conditions. Be cautious if you're pregnant, breastfeeding, or have specific health concerns. Always prioritize your safety and well-being.
NAC PLUS TABLET should only be used in children with a doctor's guidance. It is generally not recommended for children under 12 years of age due to potential risks, such as kidney damage, stomach pain, and bleeding. Always consult a healthcare provider before giving NAC PLUS TABLET to children (over 12 years old), as the dose may need to be tailored based on the child's specific needs.
NAC PLUS TABLET is composed of diclofenac (an anti-inflammatory) and acetaminophen (a fever reducer/mild analgesic), which are primarily used to relieve pain and inflammation associated with bones and muscles.
NAC PLUS TABLET is generally safe when used as directed by your doctor, especially for short-term relief of pain associated with bones and muscles. However, it should be used with caution, as prolonged use or high doses may lead to liver damage, stomach ulcers, and bleeding. Please consult your doctor if you have concerns about the safety of NAC PLUS TABLET or need personalized advice.
NAC PLUS TABLET may cause mild side effects, such as nausea and vomiting, in some individuals. It contains a nonsteroidal anti-inflammatory drug (Diclofenac), which can irritate the stomach lining, leading to nausea or vomiting. To manage these side effects, take NAC PLUS TABLET with food or a full glass of water. If the nausea or vomiting is severe, please consult a doctor.
NAC PLUS TABLET may cause dizziness as a potential side effect in some individuals. Avoid driving or operating machinery if you feel dizzy after taking NAC PLUS TABLET. Usually, these effects fade away with time. If the dizziness persists or becomes severe, please consult your doctor, as they may adjust the dosage or recommend alternative treatments.
NAC PLUS TABLET may damage the kidneys if taken in high doses or for a prolonged period, especially if you have pre-existing kidney problems. Acetaminophen can cause liver damage if overused, while diclofenac (a nonsteroidal anti-inflammatory drug) can impair kidney function. Please consult your doctor before using NAC PLUS TABLET; they may adjust the dosage if necessary.
NAC PLUS TABLET has specific contraindications, including allergies to any ingredients or other NSAIDs, active stomach ulcers or bleeding, severe liver or kidney disease, severe heart conditions (history of heart attack or stroke), asthma, and recent heart bypass surgery. However, this is not an exhaustive list. It's essential to consult your doctor for full information and determine if this medication suits you. Your doctor will assess your individual circumstances and advise whether this medication is appropriate for your needs, ensuring safe and effective treatment.
Yes, NAC PLUS TABLET and Vitamin B-complex can generally be taken together, as no known major interactions exist between them. However, it is essential to consult a healthcare provider before taking NAC PLUS TABLET with supplements or other medications to ensure safety and avoid potential interactions.
No, taking a dose higher than the recommended dose of NAC PLUS TABLET is not safe. High doses of NAC PLUS TABLET may lead to liver damage (due to acetaminophen) and increase the risk of stomach bleeding and kidney damage (due to diclofenac). Always follow the dosing instructions and consult a doctor if you are unsure.
NAC PLUS TABLET should be stored in a cool and dry place, away from direct sunlight and moisture. Keep it out of reach of children.
If you have a peptic ulcer, you should avoid taking NAC PLUS TABLET, as it may irritate the stomach lining and worsen the ulcer (especially because of diclofenac, a nonsteroidal anti-inflammatory drug [NSAID]). Please consult your healthcare provider before taking NAC PLUS TABLET to ensure it is appropriate for your condition.
NAC PLUS TABLET may cause common side effects such as stomach upset, dizziness, light-headedness, malaise, nausea, vomiting, liver dysfunction (hepatitis), pruritus (itchy skin), and rash. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Avoid taking NAC PLUS TABLET during pregnancy unless prescribed by a doctor. In particular, diclofenac (one of its ingredients) is not recommended during the last trimester, as it may harm the baby. Please consult your doctor if you have any concerns regarding this. Your doctor will prescribe it only if the benefits outweigh the risks.
It is generally not recommended to drink alcohol while taking NAC PLUS TABLET. Both alcohol and NAC PLUS TABLET can strain the liver and increase the risk of liver damage or stomach bleeding. Drinking alcohol may also increase drowsiness, so do not drive or operate machinery unless you are fully alert. Always consult your doctor for personalized advice.

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